HRP20090527T1 - Nogo-a neutralising immunoglobulins for treatment of neurological diseases - Google Patents
Nogo-a neutralising immunoglobulins for treatment of neurological diseasesInfo
- Publication number
- HRP20090527T1 HRP20090527T1 HR20090527T HRP20090527T HRP20090527T1 HR P20090527 T1 HRP20090527 T1 HR P20090527T1 HR 20090527 T HR20090527 T HR 20090527T HR P20090527 T HRP20090527 T HR P20090527T HR P20090527 T1 HRP20090527 T1 HR P20090527T1
- Authority
- HR
- Croatia
- Prior art keywords
- nogo
- neutralising
- immunoglobulins
- treatment
- neurological diseases
- Prior art date
Links
- 108060003951 Immunoglobulin Proteins 0.000 title 1
- 208000012902 Nervous system disease Diseases 0.000 title 1
- 208000025966 Neurological disease Diseases 0.000 title 1
- 102000018358 immunoglobulin Human genes 0.000 title 1
- 229940072221 immunoglobulins Drugs 0.000 title 1
- 230000003472 neutralizing effect Effects 0.000 title 1
- 108010047041 Complementarity Determining Regions Proteins 0.000 abstract 4
- 239000012634 fragment Substances 0.000 abstract 2
- 102000010410 Nogo Proteins Human genes 0.000 abstract 1
- 108010077641 Nogo Proteins Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0329684A GB0329684D0 (en) | 2003-12-22 | 2003-12-22 | Method |
| GB0329711A GB0329711D0 (en) | 2003-12-22 | 2003-12-22 | Antibodies |
| PCT/GB2004/005325 WO2005061544A2 (en) | 2003-12-22 | 2004-12-20 | Nogo-a neutralising immunoglobulins for treatment of neurological diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090527T1 true HRP20090527T1 (en) | 2009-11-30 |
Family
ID=34712703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090527T HRP20090527T1 (en) | 2003-12-22 | 2009-10-01 | Nogo-a neutralising immunoglobulins for treatment of neurological diseases |
Country Status (28)
| Country | Link |
|---|---|
| US (4) | US7988964B2 (pt) |
| EP (3) | EP2213684A3 (pt) |
| JP (2) | JP2007537145A (pt) |
| KR (1) | KR101150548B1 (pt) |
| AR (1) | AR048912A1 (pt) |
| AT (1) | ATE440866T1 (pt) |
| AU (1) | AU2004303585B2 (pt) |
| BR (1) | BRPI0417959A (pt) |
| CA (1) | CA2549956C (pt) |
| CY (1) | CY1110530T1 (pt) |
| DE (1) | DE602004022871D1 (pt) |
| DK (1) | DK1711530T3 (pt) |
| ES (1) | ES2330444T3 (pt) |
| HK (1) | HK1100144A1 (pt) |
| HR (1) | HRP20090527T1 (pt) |
| IL (1) | IL176206A (pt) |
| IS (1) | IS2739B (pt) |
| MA (1) | MA28289A1 (pt) |
| MX (1) | MXPA06007190A (pt) |
| MY (1) | MY144612A (pt) |
| NO (1) | NO20062767L (pt) |
| NZ (1) | NZ548013A (pt) |
| PL (1) | PL1711530T3 (pt) |
| PT (1) | PT1711530E (pt) |
| RU (1) | RU2362780C2 (pt) |
| SI (1) | SI1711530T1 (pt) |
| TW (1) | TWI329649B (pt) |
| WO (2) | WO2005061545A2 (pt) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1355666B1 (en) | 2000-12-22 | 2012-06-13 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Use of repulsive guidance molecule (RGM) and its modulators |
| GB0228832D0 (en) * | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| GB0321997D0 (en) * | 2003-09-19 | 2003-10-22 | Novartis Ag | Organic compound |
| DK1711530T3 (da) * | 2003-12-22 | 2009-12-14 | Glaxo Group Ltd | Nogo-A-neutraliserende immunoglobuliner til behandling af neurologiske sygdomme |
| BRPI0612734A2 (pt) * | 2005-07-05 | 2010-11-30 | Glaxo Group Ltd | anticorpo monoclonal, composição farmacêutica, métodos de promoção de brotamento axonal, e de produção de um anticorpo anti-nogo, e, uso de um anticorpo anti-nogo |
| CN101277974A (zh) | 2005-09-30 | 2008-10-01 | 阿伯特有限及两合公司 | 排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途 |
| PL2289909T3 (pl) | 2005-11-30 | 2015-04-30 | Abbvie Inc | Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał |
| US8497072B2 (en) | 2005-11-30 | 2013-07-30 | Abbott Laboratories | Amyloid-beta globulomer antibodies |
| GB0525662D0 (en) | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Immunoglobulins |
| US8663635B2 (en) | 2006-03-21 | 2014-03-04 | The Regents Of The University Of California | N-cadherin: target for cancer diagnosis and therapy |
| WO2008002594A2 (en) * | 2006-06-27 | 2008-01-03 | Neuroprotection For Life Corp. | Neuronal circuit-dependent neuroprotection by interaction between nicotinic receptors |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| AU2007329307B2 (en) * | 2006-12-07 | 2012-08-02 | Novartis Ag | Antagonist antibodies against EphB3 |
| WO2008104386A2 (en) * | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
| US20110105724A1 (en) * | 2007-08-16 | 2011-05-05 | Stephanie Jane Clegg | Novel compounds |
| SI2207808T1 (sl) * | 2007-11-02 | 2013-09-30 | Novartis Ag | Izboljšane Nogo-A vezavne molekule in njihova farmacevtska uporaba |
| US8962803B2 (en) | 2008-02-29 | 2015-02-24 | AbbVie Deutschland GmbH & Co. KG | Antibodies against the RGM A protein and uses thereof |
| JP2011521619A (ja) * | 2008-04-04 | 2011-07-28 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 腫瘍成長、血管新生および転移を妨害する癌標的に対する新規抗体 |
| JP2011527317A (ja) * | 2008-07-11 | 2011-10-27 | グラクソ グループ リミテッド | Ｎｏｇｏ−ａアンタゴニストによる筋萎縮性側索硬化症の治療 |
| US10266585B2 (en) | 2009-08-28 | 2019-04-23 | The Board Of Regents Of The Univerity Of Texas System | Methods of treating brain injury |
| PL2510001T3 (pl) | 2009-12-08 | 2016-06-30 | Abbvie Deutschland | Monoklonalne przeciwciało przeciwko białku RGM A do zastosowania w leczeniu zwyrodnienia warstwy włókien nerwowych siatkówki (RNFL) |
| US8987419B2 (en) | 2010-04-15 | 2015-03-24 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| WO2012004773A1 (en) | 2010-07-09 | 2012-01-12 | Universite De Geneve | New uses of nogo-a inhibitors and related methods |
| CA2808187A1 (en) | 2010-08-14 | 2012-02-23 | Abbvie Inc. | Amyloid-beta binding proteins |
| EP2627357B1 (en) | 2010-10-15 | 2017-05-03 | The Board of Regents of The University of Texas System | Antibodies that bind amyloid oligomers |
| EA201390575A1 (ru) | 2010-10-29 | 2014-01-30 | Иммьюноджен, Инк. | Неантагонистические egfr-связывающие молекулы и их иммуноконъюгаты |
| EP2632490A4 (en) | 2010-10-29 | 2014-10-22 | Immunogen Inc | NOVEL MOLECULES BINDING TO THE EGF RECEPTOR AND IMMUNOCONJUGATES THEREOF |
| RU2014121820A (ru) | 2011-11-21 | 2015-12-27 | Иммьюноджен, Инк. | Способ лечения опухолей, устойчивых к анти-egfr терапиям, с помощью конъюгата антитела egfr с цитотоксическим средством |
| EP2802603A4 (en) | 2012-01-09 | 2015-11-04 | Scripps Research Inst | REGIONS DETERMINING ULTRALONGUAL COMPLEMENTARYITY AND USES THEREOF |
| WO2013112922A1 (en) | 2012-01-27 | 2013-08-01 | AbbVie Deutschland GmbH & Co. KG | Composition and method for diagnosis and treatment of diseases associated with neurite degeneration |
| AU2013285493A1 (en) | 2012-07-05 | 2015-01-22 | Glaxo Group Limited | Optimum dose regime of an anti-Nogo-A antibody in the treatment of amyotrophic lateral sclerosis |
| MX2017014136A (es) | 2015-05-04 | 2018-07-06 | Cytomx Therapeutics Inc | Anticuerpos anti-cd166, anticuerpos anti-cd166 activables, y metodos de uso de los mismos. |
| US20180362660A1 (en) * | 2016-05-09 | 2018-12-20 | Schickwann Tsai | Anti-penumbra monoclonal antibodies for detection and therapy of normal and abnormal B lymphocytes |
| EP3652210A1 (en) * | 2017-07-14 | 2020-05-20 | CytomX Therapeutics, Inc. | Anti-cd166 antibodies and uses thereof |
| WO2020068058A1 (en) * | 2018-09-25 | 2020-04-02 | Academia Sinica | Anti-siglec antibody, pharmaceutical composition comprising the same, and uses thereof |
| WO2021079002A2 (en) | 2019-10-24 | 2021-04-29 | Novago Therapeutics Ag | Novel anti-nogo-a antibodies |
| WO2022119932A1 (en) * | 2020-12-02 | 2022-06-09 | Agilent Technologies, Inc. | Anti-human cd10 antibodies for use in immunohistochemistry (ihc) protocols to diagnose cancer |
| WO2024041450A1 (zh) * | 2022-08-22 | 2024-02-29 | 舒泰神（北京）生物制药股份有限公司 | 特异性识别Nogo-A的抗体及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3935074A (en) * | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| KR100316571B1 (ko) | 1994-05-27 | 2002-05-30 | 파올로 비지, 엔리꼬 카쭐라니 | 타키키닌nk3수용체길항제로서퀴놀린유도체 |
| PT1124846E (pt) * | 1998-11-06 | 2009-10-08 | Univ Zuerich | Sequências nucleotídicas e proteicas dos genes nogo e métodos baseados nestas sequências |
| FR2792199B3 (fr) | 1999-04-13 | 2001-05-18 | Sanofi Sa | Utilisation de l'osanetant pour la preparation de medicaments utiles dans le traitement des troubles de l'humeur |
| US20030113891A1 (en) * | 2000-02-11 | 2003-06-19 | Lawrence Blatt | Method and reagent for the inhibition of NOGO and NOGO receptor genes |
| GB0101313D0 (en) * | 2001-01-18 | 2001-02-28 | Glaxo Group Ltd | Assay |
| BR0309110A (pt) * | 2002-04-17 | 2007-05-08 | Upjohn Co | composições e processo de tratamento da doença de alzheimer |
| GB0228832D0 (en) * | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
| BRPI0409562A (pt) * | 2003-04-16 | 2006-04-18 | Univ Yale | tratamento de condições envolvendo placas amilóides |
| GB0318727D0 (en) | 2003-08-08 | 2003-09-10 | Smithkline Beecham Corp | Novel compounds |
| GB0321997D0 (en) * | 2003-09-19 | 2003-10-22 | Novartis Ag | Organic compound |
| DK1711530T3 (da) | 2003-12-22 | 2009-12-14 | Glaxo Group Ltd | Nogo-A-neutraliserende immunoglobuliner til behandling af neurologiske sygdomme |
-
2004
- 2004-12-20 DK DK04806128T patent/DK1711530T3/da active
- 2004-12-20 AT AT04806128T patent/ATE440866T1/de active
- 2004-12-20 MX MXPA06007190A patent/MXPA06007190A/es active IP Right Grant
- 2004-12-20 WO PCT/GB2004/005343 patent/WO2005061545A2/en not_active Application Discontinuation
- 2004-12-20 BR BRPI0417959-5A patent/BRPI0417959A/pt not_active IP Right Cessation
- 2004-12-20 EP EP09168234A patent/EP2213684A3/en not_active Withdrawn
- 2004-12-20 EP EP04806145A patent/EP1706426A2/en not_active Withdrawn
- 2004-12-20 WO PCT/GB2004/005325 patent/WO2005061544A2/en active Application Filing
- 2004-12-20 RU RU2006123481/13A patent/RU2362780C2/ru not_active IP Right Cessation
- 2004-12-20 CA CA2549956A patent/CA2549956C/en not_active Expired - Fee Related
- 2004-12-20 PT PT04806128T patent/PT1711530E/pt unknown
- 2004-12-20 MY MYPI20045254A patent/MY144612A/en unknown
- 2004-12-20 KR KR1020067014806A patent/KR101150548B1/ko not_active IP Right Cessation
- 2004-12-20 US US10/583,877 patent/US7988964B2/en not_active Expired - Fee Related
- 2004-12-20 PL PL04806128T patent/PL1711530T3/pl unknown
- 2004-12-20 JP JP2006546307A patent/JP2007537145A/ja active Pending
- 2004-12-20 SI SI200431272T patent/SI1711530T1/sl unknown
- 2004-12-20 DE DE602004022871T patent/DE602004022871D1/de active Active
- 2004-12-20 TW TW093139709A patent/TWI329649B/zh not_active IP Right Cessation
- 2004-12-20 EP EP04806128A patent/EP1711530B1/en active Active
- 2004-12-20 AU AU2004303585A patent/AU2004303585B2/en not_active Ceased
- 2004-12-20 JP JP2006544554A patent/JP4901480B2/ja not_active Expired - Fee Related
- 2004-12-20 AR ARP040104811A patent/AR048912A1/es not_active Application Discontinuation
- 2004-12-20 NZ NZ548013A patent/NZ548013A/en unknown
- 2004-12-20 ES ES04806128T patent/ES2330444T3/es active Active
-
2005
- 2005-07-06 US US11/177,648 patent/US7780964B2/en not_active Expired - Fee Related
-
2006
- 2006-06-08 IL IL176206A patent/IL176206A/en not_active IP Right Cessation
- 2006-06-12 IS IS8506A patent/IS2739B/is unknown
- 2006-06-13 NO NO20062767A patent/NO20062767L/no not_active Application Discontinuation
- 2006-07-10 MA MA29178A patent/MA28289A1/fr unknown
-
2007
- 2007-04-18 HK HK07104094.0A patent/HK1100144A1/xx not_active IP Right Cessation
-
2009
- 2009-10-01 HR HR20090527T patent/HRP20090527T1/xx unknown
- 2009-11-11 CY CY20091101175T patent/CY1110530T1/el unknown
-
2010
- 2010-08-23 US US12/861,205 patent/US20110054149A1/en not_active Abandoned
-
2013
- 2013-05-07 US US13/888,764 patent/US20140147435A1/en not_active Abandoned
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