HRP20090103T3 - Method for preparing 4 -amino-4'-demethyl-4-desoxypodophyllotoxin - Google Patents
Method for preparing 4 -amino-4'-demethyl-4-desoxypodophyllotoxinInfo
- Publication number
- HRP20090103T3 HRP20090103T3 HR20090103T HRP20090103T HRP20090103T3 HR P20090103 T3 HRP20090103 T3 HR P20090103T3 HR 20090103 T HR20090103 T HR 20090103T HR P20090103 T HRP20090103 T HR P20090103T HR P20090103 T3 HRP20090103 T3 HR P20090103T3
- Authority
- HR
- Croatia
- Prior art keywords
- desoxypodophyllotoxin
- demethyl
- amino
- preparing
- acid
- Prior art date
Links
- 239000002253 acid Substances 0.000 abstract 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Telephone Set Structure (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0507642A FR2888849B1 (fr) | 2005-07-19 | 2005-07-19 | Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine |
| PCT/EP2006/064420 WO2007010007A1 (fr) | 2005-07-19 | 2006-07-19 | PROCEDE DE PREPARATION DE LA 4β-AMINO-4'-DEMETHYL-4-DESOXYPODOPHYLLOTOXINE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090103T3 true HRP20090103T3 (en) | 2009-03-31 |
Family
ID=36035759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090103T HRP20090103T3 (en) | 2005-07-19 | 2009-02-18 | Method for preparing 4 -amino-4'-demethyl-4-desoxypodophyllotoxin |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US7932406B2 (xx) |
| EP (1) | EP1907396B1 (xx) |
| JP (1) | JP5140583B2 (xx) |
| KR (1) | KR101357664B1 (xx) |
| CN (1) | CN101223176B (xx) |
| AT (1) | ATE414707T1 (xx) |
| AU (1) | AU2006271645B2 (xx) |
| BR (1) | BRPI0613418A2 (xx) |
| CA (1) | CA2616064C (xx) |
| CY (1) | CY1108804T1 (xx) |
| DE (1) | DE602006003769D1 (xx) |
| DK (1) | DK1907396T3 (xx) |
| ES (1) | ES2317561T3 (xx) |
| FR (1) | FR2888849B1 (xx) |
| HK (1) | HK1114101A1 (xx) |
| HR (1) | HRP20090103T3 (xx) |
| IL (1) | IL188716A0 (xx) |
| MA (1) | MA29690B1 (xx) |
| MX (1) | MX2008000961A (xx) |
| NO (1) | NO20080812L (xx) |
| NZ (1) | NZ565923A (xx) |
| PL (1) | PL1907396T3 (xx) |
| PT (1) | PT1907396E (xx) |
| RS (1) | RS50782B (xx) |
| RU (1) | RU2405787C2 (xx) |
| SI (1) | SI1907396T1 (xx) |
| TN (1) | TNSN08030A1 (xx) |
| UA (1) | UA90530C2 (xx) |
| WO (1) | WO2007010007A1 (xx) |
| ZA (1) | ZA200801577B (xx) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2637886A (en) * | 1950-04-06 | 1953-05-12 | Walther Trautwein | Slide fastener |
| FR2888849B1 (fr) * | 2005-07-19 | 2007-10-05 | Pierre Fabre Medicament Sa | Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine |
| FR2921368B1 (fr) * | 2007-09-25 | 2012-10-12 | Pf Medicament | Nouveau procede de synthese de derives anticancereux de (poly) aminoalkylaminoacetamide d'epipodophyllotoxine. |
| FR2935143B1 (fr) * | 2008-08-19 | 2010-12-03 | Pf Medicament | Nouveaus derives (poly)aminoalkylaminoalkylamides, alkyl-urees, ou alkyl-sulfonamides d'epipodophyllotoxine, leur procede de preparation et leur application en therapeuthique comme agent cancereux |
| EP2448911A1 (en) | 2009-06-29 | 2012-05-09 | Merz Pharma GmbH & Co. KGaA | Method of preparing 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane |
| EP2448909B1 (en) * | 2009-06-29 | 2013-05-01 | Merz Pharma GmbH & Co. KGaA | Method of preparing 1-amino-1,3,3,5,5-pentamethylcyclohexane |
| CA2765609A1 (en) * | 2009-06-29 | 2011-01-06 | Merz Pharma Gmbh & Co. Kgaa | Method of preparing neramexane |
| CN110294764B (zh) * | 2019-07-15 | 2021-04-20 | 中国科学院兰州化学物理研究所 | 一种偶氮键连接的鬼臼毒素衍生物及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61126095A (ja) * | 1984-11-26 | 1986-06-13 | Fuji Yakuhin Kogyo Kk | 新規グルコサミン誘導体 |
| JPS62215583A (ja) * | 1986-03-14 | 1987-09-22 | Takeda Chem Ind Ltd | ピラゾリジノン誘導体およびその製造法 |
| US5332811A (en) * | 1989-09-12 | 1994-07-26 | The University Of North Carolina At Chapel Hill | Etopside analogs |
| WO2004073375A2 (en) | 2003-02-18 | 2004-09-02 | Ranbaxy Laboratories Limited | Podophyllotoxin derivatives as antitumor agents |
| FR2869035B1 (fr) * | 2004-04-16 | 2006-07-14 | Pierre Fabre Medicament Sa | Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux |
| FR2888849B1 (fr) * | 2005-07-19 | 2007-10-05 | Pierre Fabre Medicament Sa | Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine |
-
2005
- 2005-07-19 FR FR0507642A patent/FR2888849B1/fr not_active Expired - Fee Related
-
2006
- 2006-07-19 NZ NZ565923A patent/NZ565923A/en not_active IP Right Cessation
- 2006-07-19 MX MX2008000961A patent/MX2008000961A/es active IP Right Grant
- 2006-07-19 SI SI200630166T patent/SI1907396T1/sl unknown
- 2006-07-19 US US11/988,942 patent/US7932406B2/en not_active Expired - Fee Related
- 2006-07-19 AU AU2006271645A patent/AU2006271645B2/en not_active Ceased
- 2006-07-19 DK DK06764221T patent/DK1907396T3/da active
- 2006-07-19 EP EP06764221A patent/EP1907396B1/fr active Active
- 2006-07-19 BR BRPI0613418-1A patent/BRPI0613418A2/pt not_active IP Right Cessation
- 2006-07-19 JP JP2008521967A patent/JP5140583B2/ja not_active Expired - Fee Related
- 2006-07-19 AT AT06764221T patent/ATE414707T1/de active
- 2006-07-19 KR KR1020087002443A patent/KR101357664B1/ko not_active IP Right Cessation
- 2006-07-19 DE DE602006003769T patent/DE602006003769D1/de active Active
- 2006-07-19 RU RU2008106100/04A patent/RU2405787C2/ru not_active IP Right Cessation
- 2006-07-19 PL PL06764221T patent/PL1907396T3/pl unknown
- 2006-07-19 ES ES06764221T patent/ES2317561T3/es active Active
- 2006-07-19 PT PT06764221T patent/PT1907396E/pt unknown
- 2006-07-19 WO PCT/EP2006/064420 patent/WO2007010007A1/fr active Application Filing
- 2006-07-19 UA UAA200801997A patent/UA90530C2/uk unknown
- 2006-07-19 CN CN2006800262703A patent/CN101223176B/zh not_active Expired - Fee Related
- 2006-07-19 RS RSP-2009/0079A patent/RS50782B/sr unknown
- 2006-07-19 CA CA2616064A patent/CA2616064C/fr not_active Expired - Fee Related
-
2008
- 2008-01-10 IL IL188716A patent/IL188716A0/en unknown
- 2008-01-18 TN TNP2008000030A patent/TNSN08030A1/fr unknown
- 2008-02-01 MA MA30614A patent/MA29690B1/fr unknown
- 2008-02-14 NO NO20080812A patent/NO20080812L/no not_active Application Discontinuation
- 2008-02-18 ZA ZA200801577A patent/ZA200801577B/xx unknown
- 2008-08-28 HK HK08109605.0A patent/HK1114101A1/xx not_active IP Right Cessation
-
2009
- 2009-02-18 HR HR20090103T patent/HRP20090103T3/xx unknown
- 2009-02-18 CY CY20091100177T patent/CY1108804T1/el unknown
-
2010
- 2010-09-30 US US12/894,684 patent/US8193379B2/en not_active Expired - Fee Related
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