DE602006003769D1 - Verfahren zur herstellung von 4-amino-4'-demethyl-4-desoxypodophylotoxin - Google Patents

Verfahren zur herstellung von 4-amino-4'-demethyl-4-desoxypodophylotoxin

Info

Publication number
DE602006003769D1
DE602006003769D1 DE602006003769T DE602006003769T DE602006003769D1 DE 602006003769 D1 DE602006003769 D1 DE 602006003769D1 DE 602006003769 T DE602006003769 T DE 602006003769T DE 602006003769 T DE602006003769 T DE 602006003769T DE 602006003769 D1 DE602006003769 D1 DE 602006003769D1
Authority
DE
Germany
Prior art keywords
demethyl
amino
desoxypodophyllotoxin
desoxypodophylotoxine
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006003769T
Other languages
English (en)
Inventor
Yves Guminski
Martial Grousseaud
Thierry Imbert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of DE602006003769D1 publication Critical patent/DE602006003769D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Telephone Set Structure (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE602006003769T 2005-07-19 2006-07-19 Verfahren zur herstellung von 4-amino-4'-demethyl-4-desoxypodophylotoxin Active DE602006003769D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0507642A FR2888849B1 (fr) 2005-07-19 2005-07-19 Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine
PCT/EP2006/064420 WO2007010007A1 (fr) 2005-07-19 2006-07-19 PROCEDE DE PREPARATION DE LA 4β-AMINO-4'-DEMETHYL-4-DESOXYPODOPHYLLOTOXINE

Publications (1)

Publication Number Publication Date
DE602006003769D1 true DE602006003769D1 (de) 2009-01-02

Family

ID=36035759

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006003769T Active DE602006003769D1 (de) 2005-07-19 2006-07-19 Verfahren zur herstellung von 4-amino-4'-demethyl-4-desoxypodophylotoxin

Country Status (30)

Country Link
US (2) US7932406B2 (de)
EP (1) EP1907396B1 (de)
JP (1) JP5140583B2 (de)
KR (1) KR101357664B1 (de)
CN (1) CN101223176B (de)
AT (1) ATE414707T1 (de)
AU (1) AU2006271645B2 (de)
BR (1) BRPI0613418A2 (de)
CA (1) CA2616064C (de)
CY (1) CY1108804T1 (de)
DE (1) DE602006003769D1 (de)
DK (1) DK1907396T3 (de)
ES (1) ES2317561T3 (de)
FR (1) FR2888849B1 (de)
HK (1) HK1114101A1 (de)
HR (1) HRP20090103T3 (de)
IL (1) IL188716A0 (de)
MA (1) MA29690B1 (de)
MX (1) MX2008000961A (de)
NO (1) NO20080812L (de)
NZ (1) NZ565923A (de)
PL (1) PL1907396T3 (de)
PT (1) PT1907396E (de)
RS (1) RS50782B (de)
RU (1) RU2405787C2 (de)
SI (1) SI1907396T1 (de)
TN (1) TNSN08030A1 (de)
UA (1) UA90530C2 (de)
WO (1) WO2007010007A1 (de)
ZA (1) ZA200801577B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2637886A (en) * 1950-04-06 1953-05-12 Walther Trautwein Slide fastener
FR2888849B1 (fr) * 2005-07-19 2007-10-05 Pierre Fabre Medicament Sa Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine
FR2921368B1 (fr) * 2007-09-25 2012-10-12 Pf Medicament Nouveau procede de synthese de derives anticancereux de (poly) aminoalkylaminoacetamide d'epipodophyllotoxine.
FR2935143B1 (fr) 2008-08-19 2010-12-03 Pf Medicament Nouveaus derives (poly)aminoalkylaminoalkylamides, alkyl-urees, ou alkyl-sulfonamides d'epipodophyllotoxine, leur procede de preparation et leur application en therapeuthique comme agent cancereux
CA2765609A1 (en) * 2009-06-29 2011-01-06 Merz Pharma Gmbh & Co. Kgaa Method of preparing neramexane
US20120130131A1 (en) * 2009-06-29 2012-05-24 Herbert Koller Method of preparing 1-amino-1,3,3,5,5-pentamethylcyclohexane
WO2011000537A1 (en) 2009-06-29 2011-01-06 Merz Pharma Gmbh & Co. Kgaa Method of preparing 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane
CN110294764B (zh) * 2019-07-15 2021-04-20 中国科学院兰州化学物理研究所 一种偶氮键连接的鬼臼毒素衍生物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61126095A (ja) * 1984-11-26 1986-06-13 Fuji Yakuhin Kogyo Kk 新規グルコサミン誘導体
JPS62215583A (ja) * 1986-03-14 1987-09-22 Takeda Chem Ind Ltd ピラゾリジノン誘導体およびその製造法
US5332811A (en) * 1989-09-12 1994-07-26 The University Of North Carolina At Chapel Hill Etopside analogs
US20070066837A1 (en) * 2003-02-18 2007-03-22 Ahmed Kamal Podophyllotoxin derivatives as antitumor agents
FR2869035B1 (fr) * 2004-04-16 2006-07-14 Pierre Fabre Medicament Sa Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux
FR2888849B1 (fr) * 2005-07-19 2007-10-05 Pierre Fabre Medicament Sa Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine

Also Published As

Publication number Publication date
UA90530C2 (uk) 2010-05-11
RU2405787C2 (ru) 2010-12-10
ZA200801577B (en) 2009-01-28
HRP20090103T3 (en) 2009-03-31
MX2008000961A (es) 2008-03-27
TNSN08030A1 (fr) 2009-07-14
WO2007010007A1 (fr) 2007-01-25
HK1114101A1 (de) 2008-10-24
DK1907396T3 (da) 2009-03-02
AU2006271645A1 (en) 2007-01-25
MA29690B1 (fr) 2008-08-01
ES2317561T3 (es) 2009-04-16
FR2888849A1 (fr) 2007-01-26
CN101223176B (zh) 2011-06-15
US7932406B2 (en) 2011-04-26
CY1108804T1 (el) 2014-04-09
PL1907396T3 (pl) 2009-04-30
ATE414707T1 (de) 2008-12-15
RS50782B (sr) 2010-08-31
SI1907396T1 (sl) 2009-04-30
US20090137826A1 (en) 2009-05-28
US20110021791A1 (en) 2011-01-27
BRPI0613418A2 (pt) 2011-01-11
CA2616064A1 (fr) 2007-01-25
NZ565923A (en) 2010-01-29
NO20080812L (no) 2008-02-14
KR20080036058A (ko) 2008-04-24
EP1907396B1 (de) 2008-11-19
JP5140583B2 (ja) 2013-02-06
FR2888849B1 (fr) 2007-10-05
CN101223176A (zh) 2008-07-16
KR101357664B1 (ko) 2014-02-03
IL188716A0 (en) 2008-08-07
CA2616064C (fr) 2013-11-05
US8193379B2 (en) 2012-06-05
EP1907396A1 (de) 2008-04-09
JP2009501764A (ja) 2009-01-22
RU2008106100A (ru) 2009-08-27
AU2006271645B2 (en) 2012-02-02
PT1907396E (pt) 2009-02-13

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