HRP20070510T3 - Benzimidazole derivative and its use as a ii receptor antagonist - Google Patents
Benzimidazole derivative and its use as a ii receptor antagonistInfo
- Publication number
- HRP20070510T3 HRP20070510T3 HR20070510T HRP20070510T HRP20070510T3 HR P20070510 T3 HRP20070510 T3 HR P20070510T3 HR 20070510 T HR20070510 T HR 20070510T HR P20070510 T HRP20070510 T HR P20070510T HR P20070510 T3 HRP20070510 T3 HR P20070510T3
- Authority
- HR
- Croatia
- Prior art keywords
- receptor antagonist
- benzimidazole derivative
- formula
- benzimidazole
- derivative
- Prior art date
Links
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004048928 | 2004-02-25 | ||
US11/031,057 US7157584B2 (en) | 2004-02-25 | 2005-01-07 | Benzimidazole derivative and use thereof |
PCT/JP2005/003422 WO2005080384A2 (en) | 2004-02-25 | 2005-02-23 | Benzimidazole derivative and use as aii receptor antagonist |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20070510T3 true HRP20070510T3 (en) | 2007-12-31 |
Family
ID=34858222
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20070510T HRP20070510T3 (en) | 2004-02-25 | 2007-11-05 | Benzimidazole derivative and its use as a ii receptor antagonist |
HR20090593T HRP20090593T1 (hr) | 2004-02-25 | 2009-11-04 | Derivati benzimidazola i njihova uporaba kao antagonista aii receptora |
HRP20120667TT HRP20120667T2 (hr) | 2004-02-25 | 2012-08-17 | Derivat benzimidazola i njegova uporaba kao antagonista aii receptora |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20090593T HRP20090593T1 (hr) | 2004-02-25 | 2009-11-04 | Derivati benzimidazola i njihova uporaba kao antagonista aii receptora |
HRP20120667TT HRP20120667T2 (hr) | 2004-02-25 | 2012-08-17 | Derivat benzimidazola i njegova uporaba kao antagonista aii receptora |
Country Status (33)
Country | Link |
---|---|
US (3) | US7157584B2 (sl) |
EP (3) | EP1857457B1 (sl) |
JP (2) | JP4256852B2 (sl) |
KR (1) | KR101080029B1 (sl) |
CN (2) | CN101381366B (sl) |
AR (2) | AR047972A1 (sl) |
AT (2) | ATE440095T1 (sl) |
AU (1) | AU2005214271B8 (sl) |
BR (2) | BR122012009489B8 (sl) |
CA (1) | CA2557538C (sl) |
CY (5) | CY1107008T1 (sl) |
DE (3) | DE602005016162D1 (sl) |
DK (3) | DK1718641T3 (sl) |
ES (3) | ES2388945T3 (sl) |
HK (2) | HK1098472A1 (sl) |
HR (3) | HRP20070510T3 (sl) |
HU (1) | HUS1200008I1 (sl) |
IL (1) | IL177533A (sl) |
LU (1) | LU91962I2 (sl) |
MA (1) | MA28478B1 (sl) |
ME (2) | ME01643B (sl) |
MY (1) | MY142807A (sl) |
NL (1) | NL300802I2 (sl) |
NO (2) | NO332344B1 (sl) |
NZ (1) | NZ549755A (sl) |
PL (3) | PL1857457T3 (sl) |
PT (3) | PT2119715E (sl) |
RS (3) | RS50537B (sl) |
RU (2) | RU2369608C2 (sl) |
SI (3) | SI1718641T1 (sl) |
TW (1) | TWI336702B (sl) |
WO (1) | WO2005080384A2 (sl) |
ZA (1) | ZA200607241B (sl) |
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
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US7157584B2 (en) * | 2004-02-25 | 2007-01-02 | Takeda Pharmaceutical Company Limited | Benzimidazole derivative and use thereof |
US7795275B2 (en) | 2004-12-24 | 2010-09-14 | Uniquest Pty Limited | Method of treatment or prophylaxis |
JP4465469B2 (ja) * | 2005-02-21 | 2010-05-19 | 国立大学法人佐賀大学 | 循環器病マーカーとしてのインターロイキン13 |
JP4795362B2 (ja) * | 2005-03-30 | 2011-10-19 | 武田薬品工業株式会社 | ベンズイミダゾール誘導体およびその用途 |
WO2007097452A1 (ja) * | 2006-02-27 | 2007-08-30 | Takeda Pharmaceutical Company Limited | 医薬用ブリスターパッケージ |
CA2642988C (en) * | 2006-02-27 | 2015-10-27 | Takeda Pharmaceutical Company Limited | Pharmaceutical product comprising a benzimidazole in combination with a desiccant |
CN101443001B (zh) * | 2006-03-20 | 2013-11-13 | 西芬克斯医药有限公司 | 治疗或预防炎性痛的方法 |
ATE552818T1 (de) * | 2006-09-25 | 2012-04-15 | Takeda Pharmaceutical | Medizinische verpackung |
PE20130210A1 (es) * | 2007-03-28 | 2013-03-11 | Takeda Pharmaceutical | Composicion farmaceutica solida que comprende un derivado de bencimidazol y un agente de control de ph |
JP2009062296A (ja) * | 2007-09-05 | 2009-03-26 | Fujifilm Corp | カルボン酸エステル化合物の製造方法 |
WO2009113420A1 (ja) * | 2008-03-13 | 2009-09-17 | 第一三共株式会社 | オルメサルタンメドキソミルを含む製剤の溶出性の改善 |
TW201008915A (en) | 2008-07-31 | 2010-03-01 | Takeda Pharmaceutical | Solid pharmaceutical composition |
TW201014850A (en) * | 2008-09-25 | 2010-04-16 | Takeda Pharmaceutical | Solid pharmaceutical composition |
WO2010047982A1 (en) * | 2008-10-22 | 2010-04-29 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
US9387249B2 (en) | 2008-12-23 | 2016-07-12 | Takeda Pharmaceutical Company Limited | Methods of treating hypertension with at least one angiotensin II receptor blocker and chlorthalidone |
US20110009347A1 (en) * | 2009-07-08 | 2011-01-13 | Yin Liang | Combination therapy for the treatment of diabetes |
KR101931209B1 (ko) | 2010-05-11 | 2018-12-20 | 얀센 파마슈티카 엔.브이. | Sglt의 억제제로서 1-(베타-d-글루코피라노실)-2-티에닐-메틸벤젠 유도체를 포함하는 약학 제형 |
WO2012090043A1 (en) * | 2010-12-29 | 2012-07-05 | Jubilant Life Sciences Limited | Novel solid state forms of azilsartan medoxomil and preparation thereof |
US9233954B2 (en) | 2011-01-20 | 2016-01-12 | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Organic amine salts of Azilsartan, preparation method and use thereof |
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WO2013042066A1 (en) * | 2011-09-20 | 2013-03-28 | Ranbaxy Laboratories Limited | Process for the preparation of azilsartan medoxomil |
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WO2014049512A2 (en) | 2012-09-26 | 2014-04-03 | Lupin Limited | Novel process for preparation of azilsartan medoxomil |
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