HRP20040932B1 - Formulacija aerosola za inhalaciju koja sadrži tiotropijevu sol - Google Patents

Formulacija aerosola za inhalaciju koja sadrži tiotropijevu sol

Info

Publication number
HRP20040932B1
HRP20040932B1 HRP20040932AA HRP20040932A HRP20040932B1 HR P20040932 B1 HRP20040932 B1 HR P20040932B1 HR P20040932A A HRP20040932A A HR P20040932AA HR P20040932 A HRP20040932 A HR P20040932A HR P20040932 B1 HRP20040932 B1 HR P20040932B1
Authority
HR
Croatia
Prior art keywords
inhalation
aerosol formulation
tiotropium salt
formulation
copd
Prior art date
Application number
HRP20040932AA
Other languages
English (en)
Croatian (hr)
Inventor
Karin Drechsel
Barbara Niklaus-Humke
Christel Schmelzer
Petra Barth
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co.Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28458728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20040932(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma Gmbh & Co.Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co.Kg
Publication of HRP20040932A2 publication Critical patent/HRP20040932A2/hr
Publication of HRP20040932B1 publication Critical patent/HRP20040932B1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53861,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Nozzles (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HRP20040932AA 2002-04-11 2003-04-02 Formulacija aerosola za inhalaciju koja sadrži tiotropijevu sol HRP20040932B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10216036A DE10216036A1 (de) 2002-04-11 2002-04-11 Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz
PCT/EP2003/003438 WO2003084519A2 (de) 2002-04-11 2003-04-02 Aerosolformulierung für die inhalation enthaltend ein tiotropiumsalz

Publications (2)

Publication Number Publication Date
HRP20040932A2 HRP20040932A2 (en) 2005-02-28
HRP20040932B1 true HRP20040932B1 (hr) 2013-04-30

Family

ID=28458728

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20040932AA HRP20040932B1 (hr) 2002-04-11 2003-04-02 Formulacija aerosola za inhalaciju koja sadrži tiotropijevu sol

Country Status (32)

Country Link
EP (2) EP1496876B1 (enExample)
JP (1) JP2005531528A (enExample)
KR (1) KR100997219B1 (enExample)
CN (1) CN1309378C (enExample)
AR (1) AR039286A1 (enExample)
AT (1) ATE389391T1 (enExample)
AU (1) AU2003222791B2 (enExample)
BR (1) BR0309080A (enExample)
CA (1) CA2473815C (enExample)
CO (1) CO5611150A2 (enExample)
CY (1) CY1108133T1 (enExample)
DE (2) DE10216036A1 (enExample)
DK (1) DK1496876T3 (enExample)
EA (1) EA007228B1 (enExample)
EC (1) ECSP045358A (enExample)
ES (1) ES2303897T3 (enExample)
HR (1) HRP20040932B1 (enExample)
ME (1) ME00359B (enExample)
MX (1) MXPA04009818A (enExample)
MY (1) MY137249A (enExample)
NO (1) NO334915B1 (enExample)
PE (1) PE20030970A1 (enExample)
PL (1) PL371204A1 (enExample)
PT (1) PT1496876E (enExample)
RS (1) RS50923B (enExample)
SA (1) SA03240192B1 (enExample)
SI (1) SI1496876T1 (enExample)
TW (1) TWI344851B (enExample)
UA (1) UA78994C2 (enExample)
UY (1) UY27754A1 (enExample)
WO (1) WO2003084519A2 (enExample)
ZA (1) ZA200405721B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20100149T1 (hr) 2003-11-03 2010-04-30 Boehringer Ingelheim International Gmbh Postupak priprave tiotropijevih soli
AU2006277968A1 (en) * 2005-08-06 2007-02-15 Boehringer Ingelheim International Gmbh Use of tiotropium salts in the treatment of severe persistant asthma
US20070088030A1 (en) 2005-10-10 2007-04-19 Barbara Niklaus-Humke Aerosol formulations for the inhalation of beta-agonists
EP1905440A1 (de) * 2006-09-06 2008-04-02 Boehringer Ingelheim Pharma GmbH & Co. KG Verwendung einer pharmazeutischen Zusammensetzung enthaltend ein Anticholinergikum zur Abtötung von Mikroorganismen und zur Behandlung von Atemwegsinfektionen
EP2044967A1 (de) * 2007-10-01 2009-04-08 Boehringer Ingelheim Pharma GmbH & Co. KG Zerstäuber
WO2013127738A1 (de) 2012-02-28 2013-09-06 Boehringer Ingelheim International Gmbh Neue treibgashaltige tiotropium-formulierung
RU2493827C1 (ru) * 2012-10-03 2013-09-27 Шолекс Девелопмент Гмбх Стабильный комбинированный раствор фенотерола гидробромида и ипратропия бромида
WO2015065223A1 (ru) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Стабильный раствор фенотерола гидробромида
WO2015065219A1 (ru) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Раствор ипратропия бромида
GB201507686D0 (en) * 2015-05-05 2015-06-17 Norton Healthcare Ltd A stable tiotropium nebuliser solution
BR112019009278A2 (pt) * 2016-11-16 2019-10-01 Glenmark Specialty S.A. método para administrar brometo de tiotrópio e método para tratar uma doença inflamatória ou obstrutiva de via aérea
WO2021188809A1 (en) * 2020-03-19 2021-09-23 Cai Gu Huang Inhalable formulation of a solution containing levalbuterol tartrate
CN114259481A (zh) * 2021-11-26 2022-04-01 南京华盖制药有限公司 一种奥达特罗复方吸入溶液

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027959A2 (de) * 1996-12-20 1998-07-02 Boehringer Ingelheim Pharma Kg Neue wässerige arzneimittelzubereitungen zur erzeugung treibgasfreier aerosole
WO2000023037A1 (de) * 1998-10-17 2000-04-27 Boehringer Ingelheim Pharma Kg Zweikammer-kartusche für vernebler
WO2002036104A2 (de) * 2000-10-31 2002-05-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative lösungsformulierung mit einem tiotropiumsalz

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (de) 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SG45171A1 (en) 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
IL107120A (en) 1992-09-29 1997-09-30 Boehringer Ingelheim Int Atomising nozzle and filter and spray generating device
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
DE19536903C2 (de) 1995-10-04 1998-09-10 Boehringer Ingelheim Int Vorrichtung zum Haltern eines fluidischen Bauteils
DE19545226C1 (de) 1995-12-05 1997-06-19 Boehringer Ingelheim Int Sperrspannwerk für einen federbetätigten Abtrieb
DE19742439C1 (de) 1997-09-26 1998-10-22 Boehringer Ingelheim Int Mikrostrukturiertes Filter

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027959A2 (de) * 1996-12-20 1998-07-02 Boehringer Ingelheim Pharma Kg Neue wässerige arzneimittelzubereitungen zur erzeugung treibgasfreier aerosole
WO2000023037A1 (de) * 1998-10-17 2000-04-27 Boehringer Ingelheim Pharma Kg Zweikammer-kartusche für vernebler
WO2002036104A2 (de) * 2000-10-31 2002-05-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative lösungsformulierung mit einem tiotropiumsalz

Also Published As

Publication number Publication date
ES2303897T3 (es) 2008-09-01
BR0309080A (pt) 2005-02-22
WO2003084519A2 (de) 2003-10-16
ATE389391T1 (de) 2008-04-15
RS87904A (sr) 2006-12-15
AR039286A1 (es) 2005-02-16
KR20040097322A (ko) 2004-11-17
MEP54308A (en) 2011-05-10
DE10216036A1 (de) 2003-10-23
CA2473815A1 (en) 2003-10-16
PT1496876E (pt) 2008-04-15
EP1496876B1 (de) 2008-03-19
ME00359B (me) 2011-10-10
PE20030970A1 (es) 2004-01-13
TWI344851B (en) 2011-07-11
CN1646108A (zh) 2005-07-27
EA007228B1 (ru) 2006-08-25
CA2473815C (en) 2011-06-14
EP1949892A1 (de) 2008-07-30
CO5611150A2 (es) 2006-02-28
MY137249A (en) 2009-01-30
CY1108133T1 (el) 2014-02-12
SA03240192B1 (ar) 2008-01-09
EP1496876A2 (de) 2005-01-19
WO2003084519A3 (de) 2003-12-24
HRP20040932A2 (en) 2005-02-28
ZA200405721B (en) 2006-05-31
HK1078793A1 (en) 2006-03-24
EA200401305A1 (ru) 2005-06-30
JP2005531528A (ja) 2005-10-20
TW200401653A (en) 2004-02-01
AU2003222791B2 (en) 2008-09-25
MXPA04009818A (es) 2004-12-13
DE50309414D1 (de) 2008-04-30
DK1496876T3 (da) 2008-06-02
ECSP045358A (es) 2004-11-26
SI1496876T1 (sl) 2008-08-31
NO334915B1 (no) 2014-07-14
AU2003222791A1 (en) 2003-10-20
PL371204A1 (en) 2005-06-13
UA78994C2 (uk) 2007-05-10
RS50923B (sr) 2010-08-31
KR100997219B1 (ko) 2010-11-29
NO20044001L (no) 2004-10-27
UY27754A1 (es) 2003-11-28
CN1309378C (zh) 2007-04-11

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