BR0309080A - Formulação de aerossol para a inalação, que contém um sal de tiotrópio - Google Patents

Formulação de aerossol para a inalação, que contém um sal de tiotrópio

Info

Publication number
BR0309080A
BR0309080A BR0309080-9A BR0309080A BR0309080A BR 0309080 A BR0309080 A BR 0309080A BR 0309080 A BR0309080 A BR 0309080A BR 0309080 A BR0309080 A BR 0309080A
Authority
BR
Brazil
Prior art keywords
aerosol formulation
formulation containing
inhalation aerosol
tiotropium salt
active substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
BR0309080-9A
Other languages
English (en)
Inventor
Karin Drechsel
Barbara Niklaus-Humke
Christel Schmelzer
Petra Barth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28458728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0309080(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of BR0309080A publication Critical patent/BR0309080A/pt
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nozzles (AREA)

Abstract

"FORMULAçãO DE AEROSSOL PARA A INALAçãO, QUE CONTéM UM SAL DE TIOTRóPIO". A presente invenção refere-se a uma formulação de aerossol isenta de gás propulsor, de um sal de tiotrópio farmaceuticamente aceitável, dissolvido em água. A formulação de acordo com a invenção é particularmente apropriada para nebulização da substância ativa por meio de um pulverizador, para aplicar de modo inalativo a substância ativa, preferivelmente na existência das indicações Asma e COPD.
BR0309080-9A 2002-04-11 2003-04-02 Formulação de aerossol para a inalação, que contém um sal de tiotrópio Pending BR0309080A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10216036A DE10216036A1 (de) 2002-04-11 2002-04-11 Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz
PCT/EP2003/003438 WO2003084519A2 (de) 2002-04-11 2003-04-02 Aerosolformulierung für die inhalation enthaltend ein tiotropiumsalz

Publications (1)

Publication Number Publication Date
BR0309080A true BR0309080A (pt) 2005-02-22

Family

ID=28458728

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0309080-9A Pending BR0309080A (pt) 2002-04-11 2003-04-02 Formulação de aerossol para a inalação, que contém um sal de tiotrópio

Country Status (33)

Country Link
EP (2) EP1496876B1 (pt)
JP (1) JP2005531528A (pt)
KR (1) KR100997219B1 (pt)
CN (1) CN1309378C (pt)
AR (1) AR039286A1 (pt)
AT (1) ATE389391T1 (pt)
AU (1) AU2003222791B2 (pt)
BR (1) BR0309080A (pt)
CA (1) CA2473815C (pt)
CO (1) CO5611150A2 (pt)
CY (1) CY1108133T1 (pt)
DE (2) DE10216036A1 (pt)
DK (1) DK1496876T3 (pt)
EA (1) EA007228B1 (pt)
EC (1) ECSP045358A (pt)
ES (1) ES2303897T3 (pt)
HK (1) HK1078793A1 (pt)
HR (1) HRP20040932B1 (pt)
ME (1) ME00359B (pt)
MX (1) MXPA04009818A (pt)
MY (1) MY137249A (pt)
NO (1) NO334915B1 (pt)
PE (1) PE20030970A1 (pt)
PL (1) PL371204A1 (pt)
PT (1) PT1496876E (pt)
RS (1) RS50923B (pt)
SA (1) SA03240192B1 (pt)
SI (1) SI1496876T1 (pt)
TW (1) TWI344851B (pt)
UA (1) UA78994C2 (pt)
UY (1) UY27754A1 (pt)
WO (1) WO2003084519A2 (pt)
ZA (1) ZA200405721B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG137859A1 (en) 2003-11-03 2007-12-28 Boehringer Ingelheim Int Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
NZ566399A (en) * 2005-08-06 2011-07-29 Boehringer Ingelheim Int Use of tiotropium salts in the treatment of severe persistant asthma
US20070088030A1 (en) 2005-10-10 2007-04-19 Barbara Niklaus-Humke Aerosol formulations for the inhalation of beta-agonists
EP1905440A1 (de) * 2006-09-06 2008-04-02 Boehringer Ingelheim Pharma GmbH & Co. KG Verwendung einer pharmazeutischen Zusammensetzung enthaltend ein Anticholinergikum zur Abtötung von Mikroorganismen und zur Behandlung von Atemwegsinfektionen
EP2044967A1 (de) * 2007-10-01 2009-04-08 Boehringer Ingelheim Pharma GmbH & Co. KG Zerstäuber
WO2013127738A1 (de) 2012-02-28 2013-09-06 Boehringer Ingelheim International Gmbh Neue treibgashaltige tiotropium-formulierung
RU2493827C1 (ru) * 2012-10-03 2013-09-27 Шолекс Девелопмент Гмбх Стабильный комбинированный раствор фенотерола гидробромида и ипратропия бромида
WO2015065219A1 (ru) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Раствор ипратропия бромида
WO2015065223A1 (ru) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Стабильный раствор фенотерола гидробромида
GB201507686D0 (en) * 2015-05-05 2015-06-17 Norton Healthcare Ltd A stable tiotropium nebuliser solution
AU2017363041A1 (en) * 2016-11-16 2019-04-11 Glenmark Specialty S.A. Nebulized tiotropium
US20210290568A1 (en) * 2020-03-19 2021-09-23 Cai Gu Huang Inhalable formulation of a solution containing levalbuterol tartrate
CN114259481A (zh) * 2021-11-26 2022-04-01 南京华盖制药有限公司 一种奥达特罗复方吸入溶液

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (de) 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SG45171A1 (en) 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
IL107120A (en) 1992-09-29 1997-09-30 Boehringer Ingelheim Int Atomising nozzle and filter and spray generating device
DE19536903C2 (de) 1995-10-04 1998-09-10 Boehringer Ingelheim Int Vorrichtung zum Haltern eines fluidischen Bauteils
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
DE19545226C1 (de) 1995-12-05 1997-06-19 Boehringer Ingelheim Int Sperrspannwerk für einen federbetätigten Abtrieb
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
DE19742439C1 (de) 1997-09-26 1998-10-22 Boehringer Ingelheim Int Mikrostrukturiertes Filter
DE19847968A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen
EP1837021A3 (de) * 2000-10-31 2008-03-19 Boehringer Ingelheim Pharma GmbH & Co. KG Inhalative Lösungsformulierung mit einem Tiotropiumsalz

Also Published As

Publication number Publication date
AU2003222791A1 (en) 2003-10-20
PL371204A1 (en) 2005-06-13
CA2473815A1 (en) 2003-10-16
CO5611150A2 (es) 2006-02-28
SI1496876T1 (sl) 2008-08-31
ZA200405721B (en) 2006-05-31
EP1949892A1 (de) 2008-07-30
PT1496876E (pt) 2008-04-15
RS87904A (en) 2006-12-15
SA03240192B1 (ar) 2008-01-09
ES2303897T3 (es) 2008-09-01
WO2003084519A3 (de) 2003-12-24
HRP20040932A2 (en) 2005-02-28
KR100997219B1 (ko) 2010-11-29
DE50309414D1 (de) 2008-04-30
DK1496876T3 (da) 2008-06-02
AR039286A1 (es) 2005-02-16
DE10216036A1 (de) 2003-10-23
MY137249A (en) 2009-01-30
EP1496876A2 (de) 2005-01-19
HRP20040932B1 (hr) 2013-04-30
ECSP045358A (es) 2004-11-26
UA78994C2 (uk) 2007-05-10
ATE389391T1 (de) 2008-04-15
TW200401653A (en) 2004-02-01
NO20044001L (no) 2004-10-27
EA200401305A1 (ru) 2005-06-30
UY27754A1 (es) 2003-11-28
MXPA04009818A (es) 2004-12-13
NO334915B1 (no) 2014-07-14
CN1309378C (zh) 2007-04-11
EP1496876B1 (de) 2008-03-19
ME00359B (me) 2011-10-10
CA2473815C (en) 2011-06-14
HK1078793A1 (en) 2006-03-24
CY1108133T1 (el) 2014-02-12
MEP54308A (en) 2011-05-10
KR20040097322A (ko) 2004-11-17
EA007228B1 (ru) 2006-08-25
RS50923B (sr) 2010-08-31
WO2003084519A2 (de) 2003-10-16
AU2003222791B2 (en) 2008-09-25
JP2005531528A (ja) 2005-10-20
CN1646108A (zh) 2005-07-27
PE20030970A1 (es) 2004-01-13
TWI344851B (en) 2011-07-11

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI.A61K 31/46, A61K 31/536, A61K 31/5386, A61K 47/04, A61K 47/18, A61K 9/00, A61K 9/08, A61K 9/12, A61K 9/72, A61P 11/00, A61P 11/06, B05B 9/04

Ipc: A61K 31/46 (2011.01), A61K 31/536 (2011.01), A61K

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.