HRP20030823B1 - Mercaptoacetylamide derivatives, a process for their preparation and their use - Google Patents

Mercaptoacetylamide derivatives, a process for their preparation and their use

Info

Publication number
HRP20030823B1
HRP20030823B1 HR20030823A HRP20030823A HRP20030823B1 HR P20030823 B1 HRP20030823 B1 HR P20030823B1 HR 20030823 A HR20030823 A HR 20030823A HR P20030823 A HRP20030823 A HR P20030823A HR P20030823 B1 HRP20030823 B1 HR P20030823B1
Authority
HR
Croatia
Prior art keywords
aryl
alkyl
hydrogen
hydroxy
carbon atoms
Prior art date
Application number
HR20030823A
Other languages
English (en)
Croatian (hr)
Inventor
A. Flynn Gary
Mehdi Shujaath
Roger Koehl Jack
Ann Anderson Barbara
Gerken Manfred
Jablonka Bernd
Kleemann Heinz-Werner
Linz Wolfgang
Werner Seiz
Seuring Bernhard
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0119305.1A external-priority patent/GB0119305D0/en
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of HRP20030823A2 publication Critical patent/HRP20030823A2/hr
Publication of HRP20030823B1 publication Critical patent/HRP20030823B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Cephalosporin Compounds (AREA)
HR20030823A 2001-04-12 2002-04-03 Mercaptoacetylamide derivatives, a process for their preparation and their use HRP20030823B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28330501P 2001-04-12 2001-04-12
GBGB0119305.1A GB0119305D0 (en) 2001-04-12 2001-08-08 Mercaptoacetylamide derivatives,a process for their preparation and their use
PCT/EP2002/003668 WO2002083671A1 (en) 2001-04-12 2002-04-03 Mercaptoacetylamide derivatives, a process for their preparation and their use

Publications (2)

Publication Number Publication Date
HRP20030823A2 HRP20030823A2 (en) 2005-08-31
HRP20030823B1 true HRP20030823B1 (en) 2011-10-31

Family

ID=26246410

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030823A HRP20030823B1 (en) 2001-04-12 2002-04-03 Mercaptoacetylamide derivatives, a process for their preparation and their use

Country Status (26)

Country Link
EP (1) EP1381605B1 (cs)
JP (1) JP4392167B2 (cs)
CN (1) CN1245404C (cs)
AT (1) ATE286898T1 (cs)
AU (1) AU2002304804B2 (cs)
BG (1) BG66387B1 (cs)
BR (1) BR0208889A (cs)
CA (1) CA2443488C (cs)
CZ (1) CZ299708B6 (cs)
DE (1) DE60202602T2 (cs)
EE (1) EE05272B1 (cs)
ES (1) ES2232752T3 (cs)
HR (1) HRP20030823B1 (cs)
HU (1) HU229612B1 (cs)
IL (1) IL158289A0 (cs)
MA (1) MA26098A1 (cs)
MX (1) MXPA03008613A (cs)
NO (1) NO325655B1 (cs)
NZ (1) NZ528825A (cs)
OA (1) OA12502A (cs)
PL (1) PL209338B1 (cs)
PT (1) PT1381605E (cs)
RU (1) RU2286346C2 (cs)
SI (1) SI1381605T1 (cs)
SK (1) SK287616B6 (cs)
WO (1) WO2002083671A1 (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10229180A1 (de) * 2002-06-28 2004-01-29 Aventis Pharma Deutschland Gmbh Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen
US8993631B2 (en) 2010-11-16 2015-03-31 Novartis Ag Method of treating contrast-induced nephropathy

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0534363A2 (en) * 1991-09-27 1993-03-31 Merrell Pharmaceuticals Inc. Novel 2-substituted indane-2-mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5430145A (en) * 1990-10-18 1995-07-04 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
EP0671172A1 (en) * 1993-06-11 1995-09-13 Eisai Co., Ltd. Amino acid derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2053340C (en) * 1990-10-18 2002-04-02 Timothy P. Burkholder Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
RU2127261C1 (ru) * 1993-06-11 1999-03-10 Эйсаи Ко., ЛТД Производные аминокислоты

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430145A (en) * 1990-10-18 1995-07-04 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
EP0534363A2 (en) * 1991-09-27 1993-03-31 Merrell Pharmaceuticals Inc. Novel 2-substituted indane-2-mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
EP0671172A1 (en) * 1993-06-11 1995-09-13 Eisai Co., Ltd. Amino acid derivative

Also Published As

Publication number Publication date
ES2232752T3 (es) 2005-06-01
SK287616B6 (sk) 2011-04-05
NO325655B1 (no) 2008-06-30
CA2443488C (en) 2011-05-31
JP4392167B2 (ja) 2009-12-24
EE05272B1 (et) 2010-02-15
RU2003132875A (ru) 2005-03-20
DE60202602T2 (de) 2006-03-23
PL209338B1 (pl) 2011-08-31
DE60202602D1 (de) 2005-02-17
WO2002083671A1 (en) 2002-10-24
SI1381605T1 (en) 2005-06-30
HU229612B1 (en) 2014-03-28
MXPA03008613A (es) 2003-12-08
NO20034412L (no) 2003-10-02
HRP20030823A2 (en) 2005-08-31
AU2002304804B2 (en) 2007-05-10
EP1381605B1 (en) 2005-01-12
EE200300500A (et) 2003-12-15
CZ299708B6 (cs) 2008-10-29
PL363034A1 (en) 2004-11-15
HK1061690A1 (en) 2004-09-30
MA26098A1 (fr) 2004-04-01
IL158289A0 (en) 2004-05-12
HUP0303482A3 (en) 2012-12-28
BR0208889A (pt) 2004-06-29
CZ20032722A3 (cs) 2004-01-14
PT1381605E (pt) 2005-03-31
NO20034412D0 (no) 2003-10-02
ATE286898T1 (de) 2005-01-15
BG108203A (bg) 2004-12-30
SK12552003A3 (sk) 2004-03-02
BG66387B1 (bg) 2013-11-29
EP1381605A1 (en) 2004-01-21
CN1245404C (zh) 2006-03-15
RU2286346C2 (ru) 2006-10-27
CN1501926A (zh) 2004-06-02
OA12502A (fr) 2006-05-29
CA2443488A1 (en) 2002-10-24
JP2004525966A (ja) 2004-08-26
NZ528825A (en) 2005-04-29
HUP0303482A2 (hu) 2004-01-28

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
PNAN Change of the applicant name, address/residence

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, DE

ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20150306

Year of fee payment: 14

PBON Lapse due to non-payment of renewal fee

Effective date: 20160403