HRP20030748B1 - Derivati n-arilsulfonilbeta-aminokiselina sa supstituiranom aminometilnom skupinom, metode priređivanja i farmaceutski pripravci koji ih sadržavaju - Google Patents
Derivati n-arilsulfonilbeta-aminokiselina sa supstituiranom aminometilnom skupinom, metode priređivanja i farmaceutski pripravci koji ih sadržavajuInfo
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- HRP20030748B1 HRP20030748B1 HR20030748A HRP20030748A HRP20030748B1 HR P20030748 B1 HRP20030748 B1 HR P20030748B1 HR 20030748 A HR20030748 A HR 20030748A HR P20030748 A HRP20030748 A HR P20030748A HR P20030748 B1 HRP20030748 B1 HR P20030748B1
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- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
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- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
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- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
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- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
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- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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FR0104315A FR2822827B1 (fr) | 2001-03-28 | 2001-03-28 | Nouveaux derives de n-(arylsulfonyl) beta-aminoacides comportant un groupe aminomethyle substitue, leur procede de preparation et les compositions pharmaceutiques en contenant |
PCT/FR2002/001059 WO2002076964A1 (fr) | 2001-03-28 | 2002-03-27 | Derives de n-(arylsulfonyl)beta-aminoacides comportant un groupe aminomethyle substitue, leur procede de preparation et les compositions pharmaceutiques en contenant |
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HRP20030748A2 HRP20030748A2 (en) | 2004-12-31 |
HRP20030748B1 true HRP20030748B1 (hr) | 2011-11-30 |
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HR20030748A HRP20030748B1 (hr) | 2001-03-28 | 2002-03-27 | Derivati n-arilsulfonilbeta-aminokiselina sa supstituiranom aminometilnom skupinom, metode priređivanja i farmaceutski pripravci koji ih sadržavaju |
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EP (1) | EP1373233B1 (cs) |
JP (1) | JP4188695B2 (cs) |
KR (1) | KR100887038B1 (cs) |
CN (1) | CN1297546C (cs) |
AR (1) | AR033686A1 (cs) |
AT (1) | ATE372329T1 (cs) |
AU (1) | AU2002255077B2 (cs) |
BG (1) | BG108201A (cs) |
BR (1) | BR0208489A (cs) |
CA (1) | CA2436225C (cs) |
CY (1) | CY1106980T1 (cs) |
CZ (1) | CZ301337B6 (cs) |
DE (1) | DE60222248T2 (cs) |
DK (1) | DK1373233T3 (cs) |
EA (1) | EA006430B1 (cs) |
EE (1) | EE05198B1 (cs) |
ES (1) | ES2291464T3 (cs) |
FR (1) | FR2822827B1 (cs) |
HR (1) | HRP20030748B1 (cs) |
HU (1) | HUP0401538A3 (cs) |
IL (3) | IL157215A0 (cs) |
IS (1) | IS2582B (cs) |
MA (1) | MA26995A1 (cs) |
ME (1) | MEP25408A (cs) |
MX (1) | MXPA03008756A (cs) |
NO (1) | NO326519B1 (cs) |
NZ (1) | NZ527429A (cs) |
PL (1) | PL207553B1 (cs) |
PT (1) | PT1373233E (cs) |
RS (1) | RS52138B (cs) |
SK (1) | SK286753B6 (cs) |
TN (1) | TNSN03058A1 (cs) |
TW (1) | TWI233923B (cs) |
UA (1) | UA75906C2 (cs) |
WO (1) | WO2002076964A1 (cs) |
ZA (1) | ZA200306037B (cs) |
Families Citing this family (37)
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ATE286049T1 (de) * | 2001-03-30 | 2005-01-15 | Pfizer Prod Inc | Pyridazinonaldose reductase inhibitoren |
FR2840897B1 (fr) * | 2002-06-14 | 2004-09-10 | Fournier Lab Sa | Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique |
AU2004231070B2 (en) * | 2003-04-10 | 2008-02-14 | Amgen, Inc. | Bicyclic compounds having bradykinin receptors affinity and pharmaceutical compositions thereof |
JP2006525361A (ja) * | 2003-05-02 | 2006-11-09 | エラン ファーマシューティカルズ,インコーポレイテッド | ブラジキニンb1受容体アンタゴニストとしての選択された置換ピラゾール誘導体および関連化合物 |
JP4629037B2 (ja) * | 2003-05-02 | 2011-02-09 | エラン ファーマシューティカルズ,インコーポレイテッド | 炎症疾患治療のためのブラジキニンb1受容体アンタゴニストとしての4−ブロモ−5−(2−クロロ−ベンゾイルアミノ)−1h−ピラゾール−3−カルボン酸(1−(アミノカルボニル)エト−1−イル)アミド誘導体および関連化合物 |
WO2004098589A1 (en) * | 2003-05-02 | 2004-11-18 | Elan Pharmaceuticals, Inc. | 4- bromo - 5 - (2- chloro - benzoylamino) - 1h - pyrazole - 3 - carboxylic acid amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases |
EP1654232A4 (en) * | 2003-08-07 | 2008-11-12 | Merck & Co Inc | N- (BIARYLMETHYL) AMINOCYCLOPROPANECARBOXAMIDES WITH SULFONYL SUBSTITUTION |
US7790754B2 (en) * | 2003-12-22 | 2010-09-07 | Merck Sharp & Dohme Corp. | Alpha-hydroxy amides as bradykinin antagonists or inverse agonists |
EP1799637A1 (en) * | 2004-09-23 | 2007-06-27 | Amgen, Inc | Substituted sulfonamidopropionamides and methods of use |
CA2582459A1 (en) * | 2004-10-06 | 2006-04-20 | Amgen Inc. | Substituted sulfones and methods of use |
AU2005295818A1 (en) * | 2004-10-12 | 2006-04-27 | Amgen Inc. | Novel B1 bradykinin receptor antagonists |
US7612060B2 (en) | 2004-10-13 | 2009-11-03 | Amgen Inc. | Triazoles and methods of use |
US20060217362A1 (en) * | 2004-12-29 | 2006-09-28 | Tung Jay S | Novel compounds useful for bradykinin B1 receptor antagonism |
EP1741444A1 (en) * | 2005-07-05 | 2007-01-10 | Jerini AG | Kinin antagonists for treating bladder dysfunction |
ATE428702T1 (de) * | 2005-09-21 | 2009-05-15 | Reddy S Lab Eu Ltd Dr | Verfahren zur herstellung von aminosäurederivaten |
HU230518B1 (hu) | 2005-12-20 | 2016-10-28 | Richter Gedeon Nyrt. | Bradykinin B1 receptor szelektív antagonista hatással rendelkező új fenatridin származékok, eljárás előállításukra, és az ezeket tartalmazó gyógyszerkészítmények |
WO2008046573A1 (de) | 2006-10-16 | 2008-04-24 | Grünenthal GmbH | Substituierte sulfonamid-derivate als bradykinin 1 rezeptor modulatoren |
HUP0600810A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New sulfonamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
HUP0600809A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
HUP0600808A3 (en) | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New benzamide derivatives as bradykinin antagonists, process for their preparation and pharmaceutical compositions containing them |
FR2916352B1 (fr) * | 2007-05-23 | 2009-07-31 | Sanofi Aventis Sa | Utilisation d'un antagoniste non peptidique du recepteur b1 de la bradykinine pour la preparation de medicaments utiles pour la prevention ou le traitement de l'hypertension arterielle. |
WO2008153967A1 (en) * | 2007-06-08 | 2008-12-18 | Contec Therapeutics, Inc. | Bk1 antagonist conjugates |
FR2919803B1 (fr) * | 2007-08-07 | 2011-07-22 | Sanofi Aventis | Utilisation d'un antagoniste non peptidique du recepteur b1 pour la preparation de medicaments utiles pour le traitement de l'obesite et des pathologies liees a l'obesite ou au diabete |
BRPI0722156A2 (pt) * | 2007-10-27 | 2014-03-18 | Richter Gedeon Nyrt | Derivados não-peptidicos como antagonistas de bradicinina b1 |
CL2009000851A1 (es) * | 2008-04-08 | 2009-07-17 | Gruenenthal Gmbh | Compuestos derivados de sulfonamida; proceso de preparacion de estos; composicion farmaceutica que los comprende; uso en el tratamiento de dolores agudos, viscerales, neuropaticos o cronicos provocados por inflamacion, migraña, diabetes, problemas respiratorios, entre otros. |
CA2734651A1 (en) * | 2008-08-21 | 2010-02-25 | Richter Gedeon Nyrt. | Methods for treating neuropathic pain |
CA2734859A1 (en) * | 2008-08-21 | 2010-02-25 | Richter Gedeon Nyrt. | Methods for treating cns disorders |
HUP1000598A2 (en) | 2010-11-05 | 2012-09-28 | Richter Gedeon Nyrt | Indole derivatives |
AR097279A1 (es) | 2013-08-09 | 2016-03-02 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazolil-metil urea como agonistas del receptor de alx |
JP6448498B2 (ja) * | 2015-08-04 | 2019-01-09 | 日本ゴア株式会社 | 回路基板製造プロセス液用精密フィルタ |
EP3672938B1 (en) | 2017-08-25 | 2023-11-01 | The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College | Compounds for ameliorating pain |
WO2019058393A1 (en) | 2017-09-22 | 2019-03-28 | Jubilant Biosys Limited | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PAD |
IL272667B (en) | 2017-10-18 | 2022-09-01 | Jubilant Epipad LLC | Imidazo-pyridine compounds as pad inhibitors |
KR20200085836A (ko) | 2017-11-06 | 2020-07-15 | 주빌런트 프로델 엘엘씨 | Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체 |
RS65576B1 (sr) | 2017-11-24 | 2024-06-28 | Jubilant Episcribe Llc | Heterociklična jedinjenja kao inhibitori prmt5 |
CN112105610B (zh) | 2018-03-13 | 2024-01-26 | 朱比连特普罗德尔有限责任公司 | 作为pd1/pd-l1相互作用/活化的抑制剂的双环化合物 |
CN114075274B (zh) * | 2022-01-18 | 2022-04-12 | 浙江湃肽生物有限公司深圳分公司 | 一种索玛鲁肽类似物及其制备方法和用途 |
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EP0614911A1 (fr) * | 1993-02-15 | 1994-09-14 | Sanofi | Composés à groupe sulfamoyle et amidino, leur procédé de préparation et les compositions pharmaceutiques les contenant |
WO1996040639A1 (fr) * | 1995-06-07 | 1996-12-19 | Fournier Industrie Et Sante | Derives de benzenesulfonamide comme antagonistes de la bradykinine |
WO1997025315A1 (fr) * | 1996-01-11 | 1997-07-17 | Sanofi | Nouveaux derives de n-(arylsulfonyl)aminoacides ayant une affinite pour les recepteurs de la bradykinine |
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US5714497A (en) * | 1993-02-15 | 1998-02-03 | Sanofi | Compounds bearing sulphamoyl and amidino radicals, their preparation process and pharmaceutical compositions containing them |
DE19548709A1 (de) * | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosinderivate |
KR100338857B1 (ko) * | 1996-01-23 | 2002-05-30 | 시오노 요시히코 | 술폰화 아미노산 유도체 및 이를 함유한메탈로프로테이나제 저해제 |
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2003
- 2003-08-03 IL IL157215A patent/IL157215A/en not_active IP Right Cessation
- 2003-08-07 IS IS6906A patent/IS2582B/is unknown
- 2003-08-13 MA MA27279A patent/MA26995A1/fr unknown
- 2003-09-24 NO NO20034267A patent/NO326519B1/no not_active IP Right Cessation
- 2003-09-25 BG BG108201A patent/BG108201A/bg unknown
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2007
- 2007-11-07 CY CY20071101426T patent/CY1106980T1/el unknown
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2008
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0614911A1 (fr) * | 1993-02-15 | 1994-09-14 | Sanofi | Composés à groupe sulfamoyle et amidino, leur procédé de préparation et les compositions pharmaceutiques les contenant |
WO1996040639A1 (fr) * | 1995-06-07 | 1996-12-19 | Fournier Industrie Et Sante | Derives de benzenesulfonamide comme antagonistes de la bradykinine |
WO1997025315A1 (fr) * | 1996-01-11 | 1997-07-17 | Sanofi | Nouveaux derives de n-(arylsulfonyl)aminoacides ayant une affinite pour les recepteurs de la bradykinine |
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