HRP20030355A2 - Adjuvant combination formulations - Google Patents
Adjuvant combination formulations Download PDFInfo
- Publication number
- HRP20030355A2 HRP20030355A2 HR20030355A HRP20030355A HRP20030355A2 HR P20030355 A2 HRP20030355 A2 HR P20030355A2 HR 20030355 A HR20030355 A HR 20030355A HR P20030355 A HRP20030355 A HR P20030355A HR P20030355 A2 HRP20030355 A2 HR P20030355A2
- Authority
- HR
- Croatia
- Prior art keywords
- arg
- lys
- asn
- peptide
- ile
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims description 143
- 239000002671 adjuvant Substances 0.000 title claims description 99
- 238000009472 formulation Methods 0.000 title claims description 45
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- A61P31/12—Antivirals
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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- A61K2039/55522—Cytokines; Lymphokines; Interferons
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Hematology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Psychiatry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24710000P | 2000-11-10 | 2000-11-10 | |
| US33034501P | 2001-10-18 | 2001-10-18 | |
| PCT/US2001/046943 WO2002038177A2 (en) | 2000-11-10 | 2001-11-08 | Adjuvant combination formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20030355A2 true HRP20030355A2 (en) | 2005-04-30 |
Family
ID=26938452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20030355A HRP20030355A2 (en) | 2000-11-10 | 2003-05-05 | Adjuvant combination formulations |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US20040156820A1 (bg) |
| EP (1) | EP1343527A2 (bg) |
| JP (2) | JP2004523483A (bg) |
| KR (1) | KR100863368B1 (bg) |
| CN (1) | CN1533285A (bg) |
| AU (2) | AU2597202A (bg) |
| BG (1) | BG107798A (bg) |
| BR (1) | BR0115271A (bg) |
| CA (1) | CA2429000A1 (bg) |
| CZ (1) | CZ20031225A3 (bg) |
| EA (1) | EA004744B1 (bg) |
| EE (1) | EE200300172A (bg) |
| EG (1) | EG24378A (bg) |
| GE (1) | GEP20074077B (bg) |
| HR (1) | HRP20030355A2 (bg) |
| HU (1) | HUP0600589A2 (bg) |
| IL (1) | IL155690A0 (bg) |
| IS (1) | IS6809A (bg) |
| MX (1) | MXPA03004071A (bg) |
| NO (1) | NO20032086L (bg) |
| NZ (1) | NZ525887A (bg) |
| PE (1) | PE20020530A1 (bg) |
| PL (1) | PL366031A1 (bg) |
| SK (1) | SK5482003A3 (bg) |
| TW (1) | TWI239848B (bg) |
| WO (1) | WO2002038177A2 (bg) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9326174D0 (en) * | 1993-12-22 | 1994-02-23 | Biocine Sclavo | Mucosal adjuvant |
| MY144532A (en) | 2001-08-20 | 2011-09-30 | Lundbeck & Co As H | Novel method for down-regulation of amyloid |
| SG182189A1 (en) | 2003-12-17 | 2012-07-30 | Elan Pharma Int Ltd | A(beta) immunogenic peptide carrier conjugates and methods of producing same |
| WO2006047670A2 (en) * | 2004-10-26 | 2006-05-04 | Wyeth | Methods for assessing antibodies to neurodegenerative disease-associated antigens |
| KR100878585B1 (ko) | 2006-06-16 | 2009-01-15 | 국립암센터 | 글루코사민, 글루코사민 유도체 또는 이들의 염을 포함하는항암감작제 |
| CA2739318A1 (en) | 2008-08-07 | 2010-02-11 | Mercia Pharma, Llc | Immunotherapeutic compositions for the treatment of alzheimer's disease |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4666829A (en) | 1985-05-15 | 1987-05-19 | University Of California | Polypeptide marker for Alzheimer's disease and its use for diagnosis |
| US5391485A (en) | 1985-08-06 | 1995-02-21 | Immunex Corporation | DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues |
| US5078996A (en) * | 1985-08-16 | 1992-01-07 | Immunex Corporation | Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor |
| US5939074A (en) | 1986-12-30 | 1999-08-17 | The United States Of America As Represented By The Department Of Health And Human Services | Multideterminant peptide antigens |
| US6294322B1 (en) * | 1988-01-26 | 2001-09-25 | The United States Of America As Represented By The Department Of Health And Human Services | Multideterminant peptides that elicit helper T-lymphocyte cytotoxic T-lymphocyte and neutralizing antibody responses against HIV-1 |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US5993819A (en) | 1987-09-08 | 1999-11-30 | Duke University | Synthetic vaccine for protection against human immunodeficiency virus infection |
| US5019387A (en) * | 1987-09-08 | 1991-05-28 | Duke University | Production of antibodies to HIV |
| US5013548A (en) | 1987-09-08 | 1991-05-07 | Duke University | Production of antibodies to HIV |
| US5223254A (en) * | 1987-09-29 | 1993-06-29 | Praxis Biologics, Inc. | Respiratory syncytial virus: vaccines |
| CA1340506C (en) * | 1987-11-24 | 1999-04-20 | Nicholas H. Carbonetti | Production of gonorrheal pi proteins and vaccines |
| US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| DE68926859T2 (de) | 1988-11-10 | 1997-02-13 | Genetics Inst | Natürlicher killerzellen-stimulationsfaktor |
| US5073627A (en) | 1989-08-22 | 1991-12-17 | Immunex Corporation | Fusion proteins comprising GM-CSF and IL-3 |
| DE3934366A1 (de) | 1989-10-14 | 1991-04-18 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | Vakzine zum schutz vor hiv-virusinfektionen, verfahren zu ihrer herstellung und ihre verwendung als diagnostikum und immuntherapeutikum |
| PT671947E (pt) | 1991-12-02 | 2000-07-31 | Univ Texas | Composicoes para produzir respostas de linfocitos t citotoxicas contra virus |
| US6037135A (en) | 1992-08-07 | 2000-03-14 | Epimmune Inc. | Methods for making HLA binding peptides and their uses |
| CA2139756A1 (en) * | 1992-07-08 | 1994-01-20 | Eric M. Bonnem | Use of gm-csf as a vaccine adjuvant |
| US5593972A (en) | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| SG48309A1 (en) * | 1993-03-23 | 1998-04-17 | Smithkline Beecham Biolog | Vaccine compositions containing 3-0 deacylated monophosphoryl lipid a |
| ATE196737T1 (de) * | 1993-05-25 | 2000-10-15 | American Cyanamid Co | Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus |
| US5830877A (en) | 1993-08-26 | 1998-11-03 | The Regents Of The University Of California | Method, compositions and devices for administration of naked polynucleotides which encode antigens and immunostimulatory |
| US5571515A (en) * | 1994-04-18 | 1996-11-05 | The Wistar Institute Of Anatomy & Biology | Compositions and methods for use of IL-12 as an adjuvant |
| AUPM543894A0 (en) * | 1994-05-04 | 1994-05-26 | Commonwealth Scientific And Industrial Research Organisation | An adjuvant |
| US5679256A (en) * | 1994-06-20 | 1997-10-21 | Rose; Jane Anne | In-situ groundwater clean-up and radionuclide disposal method |
| DE69534922T2 (de) * | 1994-10-05 | 2006-11-23 | Vanderbilt University, Nashville | Interleukin-12 als adjuvans für paramyoxviridae impfstoffe |
| US5939075A (en) * | 1994-11-04 | 1999-08-17 | The United States Of America As Represented By The Secretary Of The Army | Mutants of Brucella melitensis |
| WO1996026277A1 (en) * | 1995-02-24 | 1996-08-29 | Cantab Pharmaceuticals Research Limited | Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation |
| US6613337B1 (en) * | 1997-02-12 | 2003-09-02 | Corixa Corporation | Leishmania antigens for use in the therapy and diagnosis of leishmaniasis |
| JPH09124697A (ja) * | 1995-11-01 | 1997-05-13 | Toagosei Co Ltd | ペプチド及びモノクローナル抗体 |
| US6096313A (en) * | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
| US5762943A (en) * | 1996-05-14 | 1998-06-09 | Ribi Immunochem Research, Inc. | Methods of treating type I hypersensitivity using monophosphoryl lipid A |
| JP3737519B2 (ja) * | 1996-05-31 | 2006-01-18 | ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー | 百日咳菌ワクチン用アジュバントとしてのｉｌ―１２ |
| US6024965A (en) | 1996-10-18 | 2000-02-15 | Erasums University Rotterdam | Induction of REV and TAT specific cytotoxic T-cells for prevention and treatment of human immunodeficiency virus (HIV) infection |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| US6797276B1 (en) * | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
| US6350456B1 (en) * | 1997-03-13 | 2002-02-26 | Corixa Corporation | Compositions and methods for the prevention and treatment of M. tuberculosis infection |
| US6113918A (en) * | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| GB9712347D0 (en) * | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| IS4518A (is) * | 1997-07-09 | 1999-01-10 | Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group | Nýtt lyfjaform fyrir bóluefni |
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| US6488936B1 (en) * | 1998-02-12 | 2002-12-03 | Wyeth | Immunogenic composition of interleukin-12 (IL-12), alum, herpes simplex viral (HSV) antigen, and method thereof |
| CA2323929C (en) | 1998-04-03 | 2004-03-09 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
| GB9907860D0 (en) * | 1999-04-07 | 1999-06-02 | Smithkline Beecham Biolog | Novel compounds |
| WO2000069456A2 (en) | 1999-05-13 | 2000-11-23 | American Cyanamid Company | Adjuvant combination formulations |
| US7396535B2 (en) * | 2003-04-25 | 2008-07-08 | Ackerman Alan H | Therapy for obsessive compulsive head banging |
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2001
- 2001-11-08 HU HU0600589A patent/HUP0600589A2/hu unknown
- 2001-11-08 EA EA200300557A patent/EA004744B1/ru not_active IP Right Cessation
- 2001-11-08 SK SK548-2003A patent/SK5482003A3/sk not_active Application Discontinuation
- 2001-11-08 CA CA002429000A patent/CA2429000A1/en not_active Abandoned
- 2001-11-08 KR KR1020037006366A patent/KR100863368B1/ko not_active IP Right Cessation
- 2001-11-08 EP EP01993474A patent/EP1343527A2/en not_active Withdrawn
- 2001-11-08 EE EEP200300172A patent/EE200300172A/xx unknown
- 2001-11-08 PE PE2001001106A patent/PE20020530A1/es not_active Application Discontinuation
- 2001-11-08 PL PL01366031A patent/PL366031A1/xx not_active Application Discontinuation
- 2001-11-08 JP JP2002540759A patent/JP2004523483A/ja active Pending
- 2001-11-08 BR BR0115271-8A patent/BR0115271A/pt not_active IP Right Cessation
- 2001-11-08 US US10/416,262 patent/US20040156820A1/en not_active Abandoned
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- 2001-11-08 AU AU2597202A patent/AU2597202A/xx active Pending
- 2001-11-08 GE GE5203A patent/GEP20074077B/en unknown
- 2001-11-08 WO PCT/US2001/046943 patent/WO2002038177A2/en active IP Right Grant
- 2001-11-08 AU AU2002225972A patent/AU2002225972B2/en not_active Ceased
- 2001-11-08 MX MXPA03004071A patent/MXPA03004071A/es not_active Application Discontinuation
- 2001-11-08 NZ NZ525887A patent/NZ525887A/en unknown
- 2001-11-08 IL IL15569001A patent/IL155690A0/xx unknown
- 2001-11-08 CN CNA018213863A patent/CN1533285A/zh active Pending
- 2001-11-09 TW TW090127895A patent/TWI239848B/zh active
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2003
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- 2003-05-10 BG BG107798A patent/BG107798A/bg unknown
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2006
- 2006-10-06 US US11/544,056 patent/US20070025959A1/en not_active Abandoned
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2009
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Also Published As
| Publication number | Publication date |
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| HUP0600589A2 (en) | 2006-11-28 |
| NZ525887A (en) | 2005-08-26 |
| IL155690A0 (en) | 2003-11-23 |
| PE20020530A1 (es) | 2002-06-18 |
| WO2002038177A2 (en) | 2002-05-16 |
| US20040156820A1 (en) | 2004-08-12 |
| CZ20031225A3 (cs) | 2003-10-15 |
| BG107798A (en) | 2004-07-30 |
| EA200300557A1 (ru) | 2004-04-29 |
| AU2597202A (en) | 2002-05-21 |
| GEP20074077B (en) | 2007-03-26 |
| MXPA03004071A (es) | 2003-09-04 |
| JP2004523483A (ja) | 2004-08-05 |
| KR20040043098A (ko) | 2004-05-22 |
| NO20032086D0 (no) | 2003-05-09 |
| PL366031A1 (en) | 2005-01-24 |
| SK5482003A3 (en) | 2004-03-02 |
| US20070025959A1 (en) | 2007-02-01 |
| CA2429000A1 (en) | 2002-05-16 |
| NO20032086L (no) | 2003-07-07 |
| EA004744B1 (ru) | 2004-08-26 |
| BR0115271A (pt) | 2005-12-13 |
| WO2002038177A3 (en) | 2003-01-16 |
| IS6809A (is) | 2003-05-07 |
| KR100863368B1 (ko) | 2008-10-13 |
| TWI239848B (en) | 2005-09-21 |
| EG24378A (en) | 2009-03-26 |
| EP1343527A2 (en) | 2003-09-17 |
| CN1533285A (zh) | 2004-09-29 |
| JP2010001304A (ja) | 2010-01-07 |
| AU2002225972B2 (en) | 2006-06-29 |
| EE200300172A (et) | 2003-06-16 |
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