EA200300557A1 - Комбинированные композиции адъювантов - Google Patents

Комбинированные композиции адъювантов

Info

Publication number
EA200300557A1
EA200300557A1 EA200300557A EA200300557A EA200300557A1 EA 200300557 A1 EA200300557 A1 EA 200300557A1 EA 200300557 A EA200300557 A EA 200300557A EA 200300557 A EA200300557 A EA 200300557A EA 200300557 A1 EA200300557 A1 EA 200300557A1
Authority
EA
Eurasian Patent Office
Prior art keywords
adjustent
compositions
combined
combination
lymphokine
Prior art date
Application number
EA200300557A
Other languages
English (en)
Other versions
EA004744B1 (ru
Inventor
Майкл Хэйджен
Original Assignee
Уайт Холдингз Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Уайт Холдингз Корпорейшн filed Critical Уайт Холдингз Корпорейшн
Publication of EA200300557A1 publication Critical patent/EA200300557A1/ru
Publication of EA004744B1 publication Critical patent/EA004744B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0007—Nervous system antigens; Prions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins
    • A61K2039/55538—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Описано применение аминоалкилглюкозаминфосфатного соединения, или его производного, или аналога в комбинации с цитокином или лимфокином, таким как гранулоцитарно-макрофагальный колониестимулирующий фактор или интерлейкин-12, в качестве комбинации адъювантов в антигенной композиции для усиления иммунной реакции у позвоночного хозяина на выбранный антиген.Отчет о международном поиске был опубликован 2003.01.16.
EA200300557A 2000-11-10 2001-11-08 Комбинированные композиции адъювантов EA004744B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24710000P 2000-11-10 2000-11-10
US33034501P 2001-10-18 2001-10-18
PCT/US2001/046943 WO2002038177A2 (en) 2000-11-10 2001-11-08 Adjuvant combination formulations

Publications (2)

Publication Number Publication Date
EA200300557A1 true EA200300557A1 (ru) 2004-04-29
EA004744B1 EA004744B1 (ru) 2004-08-26

Family

ID=26938452

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200300557A EA004744B1 (ru) 2000-11-10 2001-11-08 Комбинированные композиции адъювантов

Country Status (26)

Country Link
US (2) US20040156820A1 (ru)
EP (1) EP1343527A2 (ru)
JP (2) JP2004523483A (ru)
KR (1) KR100863368B1 (ru)
CN (1) CN1533285A (ru)
AU (2) AU2002225972B2 (ru)
BG (1) BG107798A (ru)
BR (1) BR0115271A (ru)
CA (1) CA2429000A1 (ru)
CZ (1) CZ20031225A3 (ru)
EA (1) EA004744B1 (ru)
EE (1) EE200300172A (ru)
EG (1) EG24378A (ru)
GE (1) GEP20074077B (ru)
HR (1) HRP20030355A2 (ru)
HU (1) HUP0600589A2 (ru)
IL (1) IL155690A0 (ru)
IS (1) IS6809A (ru)
MX (1) MXPA03004071A (ru)
NO (1) NO20032086L (ru)
NZ (1) NZ525887A (ru)
PE (1) PE20020530A1 (ru)
PL (1) PL366031A1 (ru)
SK (1) SK5482003A3 (ru)
TW (1) TWI239848B (ru)
WO (1) WO2002038177A2 (ru)

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MY144532A (en) 2001-08-20 2011-09-30 Lundbeck & Co As H Novel method for down-regulation of amyloid
PL2336147T3 (pl) 2003-12-17 2015-01-30 Janssen Alzheimer Immunotherap Immunogenne koniugaty A beta z nośnikiem peptydowym i sposoby ich otrzymywania
US20060160161A1 (en) * 2004-10-26 2006-07-20 Elan Pharmaceuticals, Inc. Methods for assessing antibodies to neurodegenerative disease-associated antigens
KR100878585B1 (ko) * 2006-06-16 2009-01-15 국립암센터 글루코사민, 글루코사민 유도체 또는 이들의 염을 포함하는항암감작제
US9498522B2 (en) 2008-08-07 2016-11-22 Mercia Pharma Inc. Immunotherapeutic compositions for the treatment of alzheimer'S disease

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US5078996A (en) 1985-08-16 1992-01-07 Immunex Corporation Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
US5939074A (en) 1986-12-30 1999-08-17 The United States Of America As Represented By The Department Of Health And Human Services Multideterminant peptide antigens
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US5019387A (en) 1987-09-08 1991-05-28 Duke University Production of antibodies to HIV
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US5223254A (en) * 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines
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Also Published As

Publication number Publication date
NZ525887A (en) 2005-08-26
BG107798A (en) 2004-07-30
WO2002038177A3 (en) 2003-01-16
MXPA03004071A (es) 2003-09-04
SK5482003A3 (en) 2004-03-02
US20070025959A1 (en) 2007-02-01
JP2010001304A (ja) 2010-01-07
EA004744B1 (ru) 2004-08-26
TWI239848B (en) 2005-09-21
IL155690A0 (en) 2003-11-23
IS6809A (is) 2003-05-07
AU2597202A (en) 2002-05-21
CN1533285A (zh) 2004-09-29
NO20032086D0 (no) 2003-05-09
US20040156820A1 (en) 2004-08-12
JP2004523483A (ja) 2004-08-05
EP1343527A2 (en) 2003-09-17
AU2002225972B2 (en) 2006-06-29
BR0115271A (pt) 2005-12-13
EG24378A (en) 2009-03-26
PL366031A1 (en) 2005-01-24
GEP20074077B (en) 2007-03-26
HUP0600589A2 (en) 2006-11-28
EE200300172A (et) 2003-06-16
NO20032086L (no) 2003-07-07
CA2429000A1 (en) 2002-05-16
WO2002038177A2 (en) 2002-05-16
CZ20031225A3 (cs) 2003-10-15
KR100863368B1 (ko) 2008-10-13
PE20020530A1 (es) 2002-06-18
HRP20030355A2 (en) 2005-04-30
KR20040043098A (ko) 2004-05-22

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU