HRP20030050B1 - Sustained-release preparations of quinolone antibiotics and method for preparation thereof - Google Patents

Sustained-release preparations of quinolone antibiotics and method for preparation thereof

Info

Publication number
HRP20030050B1
HRP20030050B1 HR20030050A HRP20030050A HRP20030050B1 HR P20030050 B1 HRP20030050 B1 HR P20030050B1 HR 20030050 A HR20030050 A HR 20030050A HR P20030050 A HRP20030050 A HR P20030050A HR P20030050 B1 HRP20030050 B1 HR P20030050B1
Authority
HR
Croatia
Prior art keywords
sustained
preparation
release preparations
quinolone antibiotics
mixture
Prior art date
Application number
HR20030050A
Other languages
English (en)
Croatian (hr)
Inventor
Kanikanti Venkata-Rangarao
Rupp Roland
Weber Wolfgang
Deuringer Peter
Henck Jan-Olav
Stass Heino
Takaaki Nishioka
Katakawa Yoshifumi
Taniguchi Chika
Ichihashi Hitoshi
Original Assignee
Bayer Schering Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Aktiengesellschaft filed Critical Bayer Schering Pharma Aktiengesellschaft
Publication of HRP20030050A2 publication Critical patent/HRP20030050A2/hr
Publication of HRP20030050B1 publication Critical patent/HRP20030050B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HR20030050A 2000-06-26 2003-01-24 Sustained-release preparations of quinolone antibiotics and method for preparation thereof HRP20030050B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10031043A DE10031043A1 (de) 2000-06-26 2000-06-26 Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
PCT/EP2001/006695 WO2002000219A1 (fr) 2000-06-26 2001-06-13 Preparations a liberation prolongee a base d'antibiotiques de type quinolones et procede d'elaboration desdites preparations

Publications (2)

Publication Number Publication Date
HRP20030050A2 HRP20030050A2 (en) 2004-06-30
HRP20030050B1 true HRP20030050B1 (en) 2011-07-31

Family

ID=7646816

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030050A HRP20030050B1 (en) 2000-06-26 2003-01-24 Sustained-release preparations of quinolone antibiotics and method for preparation thereof

Country Status (41)

Country Link
US (3) US7709022B2 (fr)
EP (1) EP1296685B1 (fr)
JP (1) JP4958373B2 (fr)
KR (1) KR100939617B1 (fr)
CN (1) CN1273138C (fr)
AR (1) AR029688A1 (fr)
AT (1) ATE355062T1 (fr)
AU (1) AU2001270573A1 (fr)
BG (1) BG65914B1 (fr)
BR (1) BRPI0111911B8 (fr)
CA (1) CA2414271C (fr)
CU (1) CU23264B7 (fr)
CY (1) CY1107574T1 (fr)
CZ (1) CZ301812B6 (fr)
DE (2) DE10031043A1 (fr)
DK (1) DK1296685T3 (fr)
DO (1) DOP2001000199A (fr)
EE (1) EE04992B1 (fr)
ES (1) ES2282270T3 (fr)
GT (1) GT200100126A (fr)
HK (1) HK1058479A1 (fr)
HN (1) HN2001000132A (fr)
HR (1) HRP20030050B1 (fr)
HU (1) HU229806B1 (fr)
IL (2) IL153333A0 (fr)
MA (1) MA25761A1 (fr)
MX (1) MXPA02012727A (fr)
MY (1) MY140994A (fr)
NO (1) NO325415B1 (fr)
NZ (1) NZ523352A (fr)
PE (1) PE20020207A1 (fr)
PL (1) PL203710B1 (fr)
PT (1) PT1296685E (fr)
RU (1) RU2332204C2 (fr)
SI (1) SI1296685T1 (fr)
SK (1) SK287384B6 (fr)
SV (1) SV2002000505A (fr)
TW (1) TWI279232B (fr)
UA (1) UA83616C2 (fr)
WO (1) WO2002000219A1 (fr)
ZA (1) ZA200210350B (fr)

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DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
AU2003237056A1 (en) * 2002-06-25 2004-01-06 Micro Science Tech Co., Ltd. Polymer resin formulation having anti-microbial or anti-cogulability and preparation method thereof
AU2004210399B2 (en) * 2003-02-10 2010-02-18 Bayer Intellectual Property Gmbh Treatment of bacterial diseases of the respiratory organs by locally applying fluoroquinolones
WO2004073729A1 (fr) 2003-02-21 2004-09-02 Translational Research Ltd. Compositions destinees a l'administration nasale d'un medicament
CN1758930B (zh) 2003-03-27 2010-06-09 株式会社新日本科学 鼻腔用粉末药剂喷药装置
WO2005011682A1 (fr) * 2003-08-04 2005-02-10 Kyorin Pharmaceutical Co., Ltd. Comprime a liberation prolongee pour l'administration par voie orale
US7943585B2 (en) * 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
WO2006007323A2 (fr) * 2004-06-28 2006-01-19 Alza Corporation Formes posologiques pour agents pharmaceutiques exempts d'acides a taux de dissolution et/ou de solubilite bas
WO2006060672A2 (fr) * 2004-12-03 2006-06-08 Dr. Reddy's Laboratories Ltd. Compositions de ciprofloxacine a liberation modifiee
ME02003B (fr) * 2005-04-11 2012-12-31 Abbott Lab Compositions pharmaceutiques presentant des profils de dissolution ameliores pour des medicaments peu solubles
EP1880722B1 (fr) * 2006-07-19 2010-03-17 Tabuk Pharmaceutical Manufacturing Co. Préparations pharmaceutiques des Ciprofloxacin
EP2116264B1 (fr) 2006-12-26 2017-09-27 Shin Nippon Biomedical Laboratories, Ltd. Préparation pour administration transnasale
EP2276465B1 (fr) * 2008-03-21 2014-10-22 Mylan Pharmaceuticals, Inc. Formulation à libération prolongée contenant une cire
EA029018B1 (ru) * 2009-02-13 2018-01-31 Ромарк Лабораториз Л.С. Фармацевтические составы нитазоксанида с контролируемым высвобождением
EP2429495A4 (fr) * 2009-05-15 2014-01-22 Shin Nippon Biomedical Lab Ltd Compositions pharmaceutiques intranasales avec pharmacocinétique améliorée
US11033624B2 (en) * 2010-06-02 2021-06-15 Novaflux Inc. Medical item for prevention and treatment of ear infection
CN102247313A (zh) * 2010-06-11 2011-11-23 北京润德康医药技术有限公司 一种以莫西沙星为活性成分的口服缓释固体制剂
US10285865B2 (en) 2014-05-02 2019-05-14 Novaflux Inc. Drug-releasing device usable in mucosal body cavities
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices

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US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
US5286754A (en) * 1986-01-21 1994-02-15 Bayer Aktiengesellschaft Pharmaceutical formulations of ciprofloxacin
US6261601B1 (en) * 1997-09-19 2001-07-17 Ranbaxy Laboratories Limited Orally administered controlled drug delivery system providing temporal and spatial control
WO1999015172A1 (fr) * 1997-09-25 1999-04-01 Bayer Aktiengesellschaft Formulation medicamenteuse a liberation controlee du principe actif

Also Published As

Publication number Publication date
CZ301812B6 (cs) 2010-06-30
IL153333A (en) 2010-05-31
IL153333A0 (en) 2003-07-06
UA83616C2 (uk) 2008-08-11
AR029688A1 (es) 2003-07-10
WO2002000219A1 (fr) 2002-01-03
US20070065509A1 (en) 2007-03-22
DOP2001000199A (es) 2002-05-15
ATE355062T1 (de) 2006-03-15
EE04992B1 (et) 2008-04-15
SK18212002A3 (sk) 2003-04-01
CA2414271C (fr) 2005-09-27
AU2001270573A1 (en) 2002-01-08
BG107372A (bg) 2003-09-30
CA2414271A1 (fr) 2002-12-23
EE200200707A (et) 2004-08-16
ES2282270T3 (es) 2007-10-16
NZ523352A (en) 2004-08-27
PL360632A1 (en) 2004-09-20
US20040024018A1 (en) 2004-02-05
MA25761A1 (fr) 2003-04-01
KR100939617B1 (ko) 2010-02-01
JP2004504278A (ja) 2004-02-12
NO325415B1 (no) 2008-04-21
US20070237824A1 (en) 2007-10-11
SI1296685T1 (sl) 2007-06-30
PE20020207A1 (es) 2002-04-27
US7780986B2 (en) 2010-08-24
SV2002000505A (es) 2002-12-02
BR0111911A (pt) 2003-05-13
HU229806B1 (en) 2014-07-28
HK1058479A1 (en) 2004-05-21
JP4958373B2 (ja) 2012-06-20
CN1273138C (zh) 2006-09-06
HN2001000132A (es) 2001-09-11
SK287384B6 (sk) 2010-08-09
MXPA02012727A (es) 2003-05-14
NO20026160L (no) 2002-12-20
BRPI0111911B1 (pt) 2015-08-25
NO20026160D0 (no) 2002-12-20
HUP0300953A3 (en) 2009-04-28
DE10031043A1 (de) 2002-02-14
HUP0300953A2 (hu) 2003-08-28
PL203710B1 (pl) 2009-11-30
DE50112123D1 (de) 2007-04-12
CU23264B7 (es) 2008-03-14
DK1296685T3 (da) 2007-05-07
HRP20030050A2 (en) 2004-06-30
RU2332204C2 (ru) 2008-08-27
ZA200210350B (en) 2004-02-10
GT200100126A (es) 2002-01-31
CN1438889A (zh) 2003-08-27
US7709022B2 (en) 2010-05-04
TWI279232B (en) 2007-04-21
EP1296685A1 (fr) 2003-04-02
US8187632B2 (en) 2012-05-29
KR20030023883A (ko) 2003-03-20
BG65914B1 (bg) 2010-05-31
CY1107574T1 (el) 2013-03-13
MY140994A (en) 2010-02-12
PT1296685E (pt) 2007-05-31
EP1296685B1 (fr) 2007-02-28
CZ20024216A3 (cs) 2003-04-16
BRPI0111911B8 (pt) 2021-05-25

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