HRP20020187A2 - Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-ones and their use as lipase inhibitors - Google Patents

Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-ones and their use as lipase inhibitors Download PDF

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Publication number
HRP20020187A2
HRP20020187A2 HR20020187A HRP20020187A HRP20020187A2 HR P20020187 A2 HRP20020187 A2 HR P20020187A2 HR 20020187 A HR20020187 A HR 20020187A HR P20020187 A HRP20020187 A HR P20020187A HR P20020187 A2 HRP20020187 A2 HR P20020187A2
Authority
HR
Croatia
Prior art keywords
alkyl
substituted
phenyl
oxdiazol
aryl
Prior art date
Application number
HR20020187A
Other languages
English (en)
Croatian (hr)
Inventor
Stefan Petry
Karl Schoenafinger
Guenter Mueller
Karl-Heinz Baringhaus
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of HRP20020187A2 publication Critical patent/HRP20020187A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HR20020187A 1999-09-04 2000-08-22 Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-ones and their use as lipase inhibitors HRP20020187A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19942354A DE19942354A1 (de) 1999-09-04 1999-09-04 Substituierte 3-Phenyl-5-alkoxi-1,3,4-oxdiazol-2-one, ihre Herstellung und Verwendung in Arzneimitteln
PCT/EP2000/008150 WO2001017981A1 (de) 1999-09-04 2000-08-22 Substituierte 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-one und ihre verwendung als lipase-hemmer

Publications (1)

Publication Number Publication Date
HRP20020187A2 true HRP20020187A2 (en) 2004-02-29

Family

ID=7920884

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020187A HRP20020187A2 (en) 1999-09-04 2000-08-22 Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-ones and their use as lipase inhibitors

Country Status (30)

Country Link
US (1) US6596742B1 (enExample)
EP (1) EP1214302B1 (enExample)
JP (1) JP2003508522A (enExample)
KR (1) KR100723817B1 (enExample)
CN (1) CN1152024C (enExample)
AR (1) AR032430A1 (enExample)
AT (1) ATE253059T1 (enExample)
AU (1) AU781330B2 (enExample)
BR (1) BR0013765A (enExample)
CA (1) CA2383731A1 (enExample)
CZ (1) CZ2002772A3 (enExample)
DE (2) DE19942354A1 (enExample)
DK (1) DK1214302T3 (enExample)
EE (1) EE04811B1 (enExample)
ES (1) ES2204685T3 (enExample)
HK (1) HK1048318B (enExample)
HR (1) HRP20020187A2 (enExample)
HU (1) HUP0202988A3 (enExample)
IL (2) IL148275A0 (enExample)
MX (1) MXPA02001834A (enExample)
NO (1) NO323129B1 (enExample)
NZ (1) NZ517551A (enExample)
PL (1) PL197314B1 (enExample)
PT (1) PT1214302E (enExample)
RU (1) RU2265600C2 (enExample)
SK (1) SK285924B6 (enExample)
TR (1) TR200200553T2 (enExample)
WO (1) WO2001017981A1 (enExample)
YU (1) YU10402A (enExample)
ZA (1) ZA200201594B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10102265C1 (de) * 2001-01-18 2002-08-08 Aventis Pharma Gmbh Substituierte 3-Phenyl-5-alkoxi-1,3,4-oxdiazol-2-one, ihre Herstellung und Verwendung in Arzneistoffen
DE10208987A1 (de) * 2002-02-28 2003-09-11 Aventis Pharma Gmbh Substituierte 3-Phenyl-5-alkoxi-1,3,4-oxidiazol-2-one, ihre Herstellung und Verwendung in Arzneistoffen
DE10208986A1 (de) * 2002-02-28 2003-09-11 Aventis Pharma Gmbh Verwendung substituierter 3-Phenyl-5-alkoxi-1,3,4-oxdiazol-2-one zur Herstellung von Arzneimitteln mit hemmender Wirkung an der pankreatischen Lipase
US6900233B2 (en) 2002-02-28 2005-05-31 Aventis Pharma Deutschland Gmbh Substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadiazol-2-ones, pharmaceutical composition and method for treating obesity thereof
DE10247680B4 (de) * 2002-10-12 2005-09-01 Aventis Pharma Deutschland Gmbh Neue bicyclische Inhibitoren der Hormon Sensitiven Lipase
US7208504B2 (en) 2002-10-12 2007-04-24 Sanofi-Aventis Deutschland Gmbh Bicyclic inhibitors of hormone sensitive lipase
US7799915B2 (en) * 2004-10-13 2010-09-21 Wyeth Llc Anilino-pyrimidine analogs
WO2009009287A2 (en) * 2007-07-12 2009-01-15 Deviris Inc. Hormone sensitive lipase modulators and methods of use
BRPI0821482A2 (pt) * 2007-12-27 2015-07-14 Bial Portela & Ca Sa 3-n-fenil-1,3,4-oxadiazolona 5-o-substituída, seu uso, sua composição e seu processo de preparação
AR074978A1 (es) 2008-12-23 2011-03-02 Bial Portela & Ca Sa 3-n-aril-1,3,4-oxadiazolonas 5-o-sustituidas para uso en el tratamiento del dolor y procedimiento de obtencion
US8501768B2 (en) * 2011-05-17 2013-08-06 Hoffmann-La Roche Inc. Hexahydrocyclopentapyrrolone, hexahydropyrrolopyrrolone, octahydropyrrolopyridinone and octahydropyridinone compounds
CN114163351B (zh) * 2020-09-11 2024-01-23 江苏优嘉植物保护有限公司 噁虫酮中间体2-(2-甲氧基)苯肼甲酸甲酯合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB518042A (en) 1937-09-15 1940-02-15 Ljungstroms Angturbin Ab Improvements in elastic fluid turbines of the double rotation type
FR2299328A1 (fr) 1975-02-03 1976-08-27 Rhone Poulenc Ind Derives de l'alcoyloxy-5 phenyl-3 oxyde azo
US4076824A (en) 1975-02-03 1978-02-28 Rhone-Poulenc Industries Anthelmintic oxadiazolinone derivatives
FR2299028A1 (fr) 1975-02-03 1976-08-27 Rhone Poulenc Ind Nouvea
DK156439C (da) 1980-09-15 1990-01-22 Shell Int Research 7-substituerede 2,3-dihydrobenzofuranderivater samt pesticidpraeparater indeholdende disse og en fremgangsmaade til bekaempelse af skadelige organismer
EP0067471B1 (en) 1981-06-15 1985-11-06 Shell Internationale Researchmaatschappij B.V. 7-substituted 2,3-dihydrobenzofurans, their preparation and their use as pesticides or as chemical intermediates
JPS60115502A (ja) * 1983-11-28 1985-06-22 Mitsubishi Chem Ind Ltd 殺虫剤
DE3931843A1 (de) 1989-09-23 1991-04-04 Bayer Ag Substituierte 1,3,4-oxa(thia)diazolinone verfahren zu ihrer herstellung und ihre verwendung der bekaempfung von endoparasiten
US5236939A (en) 1989-09-23 1993-08-17 Bayer Aktiengesellschaft Substituted 1,3,4-oxa(thia)diazolinones process for their preparation and their use of combating endoparasites
US5641796A (en) * 1994-11-01 1997-06-24 Eli Lilly And Company Oral hypoglycemic agents

Also Published As

Publication number Publication date
SK285924B6 (sk) 2007-11-02
YU10402A (sh) 2004-11-25
DE50004274D1 (de) 2003-12-04
PT1214302E (pt) 2004-03-31
EP1214302B1 (de) 2003-10-29
HK1048318A1 (en) 2003-03-28
JP2003508522A (ja) 2003-03-04
AR032430A1 (es) 2003-11-12
IL148275A0 (en) 2002-09-12
PL353214A1 (en) 2003-11-03
EE200200109A (et) 2003-06-16
ES2204685T3 (es) 2004-05-01
ATE253059T1 (de) 2003-11-15
EE04811B1 (et) 2007-04-16
NZ517551A (en) 2003-10-31
NO323129B1 (no) 2007-01-08
HUP0202988A3 (en) 2004-12-28
KR100723817B1 (ko) 2007-06-04
HUP0202988A2 (hu) 2002-12-28
TR200200553T2 (tr) 2002-06-21
IL148275A (en) 2008-08-07
NO20021007D0 (no) 2002-02-28
NO20021007L (no) 2002-02-28
CN1152024C (zh) 2004-06-02
MXPA02001834A (es) 2002-08-12
DE19942354A1 (de) 2001-03-08
AU781330B2 (en) 2005-05-19
EP1214302A1 (de) 2002-06-19
WO2001017981A1 (de) 2001-03-15
DK1214302T3 (da) 2004-02-16
BR0013765A (pt) 2002-04-30
HK1048318B (zh) 2004-12-10
RU2265600C2 (ru) 2005-12-10
CZ2002772A3 (cs) 2002-05-15
PL197314B1 (pl) 2008-03-31
SK3012002A3 (en) 2002-06-04
CN1371369A (zh) 2002-09-25
KR20020024336A (ko) 2002-03-29
CA2383731A1 (en) 2001-03-15
AU7411200A (en) 2001-04-10
US6596742B1 (en) 2003-07-22
ZA200201594B (en) 2003-04-30

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A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
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Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, DE

ODRP Renewal fee for the maintenance of a patent

Payment date: 20080808

Year of fee payment: 9

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