HN2003000080A - Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos y procedimientos para su uso - Google Patents

Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos y procedimientos para su uso

Info

Publication number
HN2003000080A
HN2003000080A HN2003000080A HN2003000080A HN2003000080A HN 2003000080 A HN2003000080 A HN 2003000080A HN 2003000080 A HN2003000080 A HN 2003000080A HN 2003000080 A HN2003000080 A HN 2003000080A HN 2003000080 A HN2003000080 A HN 2003000080A
Authority
HN
Honduras
Prior art keywords
useful
tienopiridins
antiangiogen
indolil
procedures
Prior art date
Application number
HN2003000080A
Other languages
English (en)
Spanish (es)
Inventor
Robert Steven Kania
William Henry Romines Iii
Stephan James Cripps
Mingying He
Jihong Lou
Ru Zhou
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HN2003000080A publication Critical patent/HN2003000080A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HN2003000080A 2002-03-01 2003-02-27 Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos y procedimientos para su uso HN2003000080A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36095202P 2002-03-01 2002-03-01

Publications (1)

Publication Number Publication Date
HN2003000080A true HN2003000080A (es) 2004-05-05

Family

ID=27789048

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2003000080A HN2003000080A (es) 2002-03-01 2003-02-27 Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos y procedimientos para su uso

Country Status (15)

Country Link
US (1) US6833456B2 (https=)
EP (1) EP1483268A2 (https=)
JP (1) JP2005527511A (https=)
AR (1) AR040398A1 (https=)
AU (1) AU2003206068A1 (https=)
BR (1) BR0308162A (https=)
CA (1) CA2478050A1 (https=)
GT (1) GT200300046A (https=)
HN (1) HN2003000080A (https=)
MX (1) MXPA04008403A (https=)
PA (1) PA8568101A1 (https=)
PE (1) PE20030944A1 (https=)
TW (1) TW200306193A (https=)
UY (1) UY27685A1 (https=)
WO (1) WO2003074529A2 (https=)

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TW200503994A (en) * 2003-01-24 2005-02-01 Novartis Ag Organic compounds
EA009994B1 (ru) * 2003-12-23 2008-06-30 Пфайзер Инк. Новые хинолиновые производные
AU2008202205B2 (en) * 2003-12-23 2009-09-10 Pfizer Inc. Novel quinoline derivatives
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GB0412467D0 (en) * 2004-06-04 2004-07-07 Astrazeneca Ab Chemical compounds
KR101257343B1 (ko) 2004-07-30 2013-04-23 메틸진 인코포레이티드 Ｖｅｇｆ 수용체 및 ｈｇｆ 수용체 신호전달 억제제
AU2006313456B2 (en) * 2005-05-20 2011-06-23 Methylgene Inc. Inhibitors of VEGF receptor and HGF receptor signaling
CN101796055B (zh) 2005-05-20 2013-09-04 梅特希尔基因公司 Vegf受体和hgf受体信号的抑制剂
MX2008001838A (es) 2005-08-08 2008-04-09 Pfizer Sales y polimorfos de un inhibidor de vegf-r.
JP2009526761A (ja) * 2006-01-30 2009-07-23 アレイ バイオファーマ、インコーポレイテッド ヘテロ二環式チオフェン化合物および使用の方法
WO2007107005A1 (en) * 2006-03-22 2007-09-27 Methylgene, Inc. Inhibitors of protein tyrosine kinase activity
JP2009539878A (ja) * 2006-06-08 2009-11-19 アレイ バイオファーマ、インコーポレイテッド キノリン化合物および使用方法
BRPI0908573A2 (pt) 2008-03-05 2012-12-25 Methylgene Inc inibidores da atividade de proteÍna tirosina quinase
KR101126736B1 (ko) * 2008-11-27 2012-04-12 주식회사 레고켐 바이오사이언스 티로신 키나아제 저해 화합물, 이의 이성질체 또는 이의 약학적으로 허용가능한 염 및 이를 포함하는 약학적 조성물
CA2806701A1 (en) 2010-07-29 2012-02-02 Bial - Portela & Ca, S.A. Process for the synthesis of substituted urea compounds
MX2014000648A (es) 2011-07-19 2014-09-25 Infinity Pharmaceuticals Inc Compuestos heterociclicos y sus usos.
CA2929742C (en) 2013-12-04 2022-09-20 Evotec International Gmbh Sulfoximine substituted quinazolines for pharmaceutical compositions
EA201691831A1 (ru) 2014-04-25 2017-02-28 Пфайзер Инк. Гетероароматические соединения и их применение в качестве допаминовых d1 лигандов
CN115746017B (zh) * 2022-11-30 2024-06-07 英维沃化工科技(广州)有限公司 一种噻吩并嘧啶类化合物及其制备方法和应用
CN116082214A (zh) * 2023-02-24 2023-05-09 常州大学 一种2-芳基-3-叔丁基吲哚类化合物、制备方法及其应用

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Also Published As

Publication number Publication date
CA2478050A1 (en) 2003-09-12
EP1483268A2 (en) 2004-12-08
WO2003074529A2 (en) 2003-09-12
MXPA04008403A (es) 2004-11-26
JP2005527511A (ja) 2005-09-15
PE20030944A1 (es) 2003-11-08
BR0308162A (pt) 2004-12-07
PA8568101A1 (es) 2003-11-12
TW200306193A (en) 2003-11-16
AU2003206068A1 (en) 2003-09-16
AU2003206068A8 (en) 2003-09-16
WO2003074529A3 (en) 2003-12-24
GT200300046A (es) 2003-10-10
UY27685A1 (es) 2003-10-31
AR040398A1 (es) 2005-04-06
US20040019065A1 (en) 2004-01-29
US6833456B2 (en) 2004-12-21

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