HN1996000065A - Procedimiento e intermedios para preparar 1 bencil - 4 - (5, 6 demetoxi - indanon) 2 - il) metilpiperidina. - Google Patents

Procedimiento e intermedios para preparar 1 bencil - 4 - (5, 6 demetoxi - indanon) 2 - il) metilpiperidina.

Info

Publication number
HN1996000065A
HN1996000065A HN1996000065A HN1996000065A HN1996000065A HN 1996000065 A HN1996000065 A HN 1996000065A HN 1996000065 A HN1996000065 A HN 1996000065A HN 1996000065 A HN1996000065 A HN 1996000065A HN 1996000065 A HN1996000065 A HN 1996000065A
Authority
HN
Honduras
Prior art keywords
demetoxi
indanon
methylpiperidine
intermediates
benzyl
Prior art date
Application number
HN1996000065A
Other languages
English (en)
Spanish (es)
Original Assignee
Inc Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inc Pfizer filed Critical Inc Pfizer
Publication of HN1996000065A publication Critical patent/HN1996000065A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
HN1996000065A 1995-12-15 1996-10-15 Procedimiento e intermedios para preparar 1 bencil - 4 - (5, 6 demetoxi - indanon) 2 - il) metilpiperidina. HN1996000065A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US875395P 1995-12-15 1995-12-15

Publications (1)

Publication Number Publication Date
HN1996000065A true HN1996000065A (es) 1997-06-26

Family

ID=21733469

Family Applications (1)

Application Number Title Priority Date Filing Date
HN1996000065A HN1996000065A (es) 1995-12-15 1996-10-15 Procedimiento e intermedios para preparar 1 bencil - 4 - (5, 6 demetoxi - indanon) 2 - il) metilpiperidina.

Country Status (33)

Country Link
EP (1) EP0883607A1 (ro)
JP (1) JP3066083B2 (ro)
KR (1) KR20000064387A (ro)
AP (1) AP708A (ro)
AR (1) AR004368A1 (ro)
AU (1) AU716462B2 (ro)
BG (1) BG102525A (ro)
BR (1) BR9612018A (ro)
CA (1) CA2237647A1 (ro)
CO (1) CO4750831A1 (ro)
CZ (1) CZ180898A3 (ro)
DZ (1) DZ2141A1 (ro)
GT (1) GT199600092A (ro)
HN (1) HN1996000065A (ro)
HR (1) HRP960592A2 (ro)
HU (1) HUP9904275A3 (ro)
IL (3) IL136421A0 (ro)
IS (1) IS4752A (ro)
MA (1) MA24032A1 (ro)
NO (1) NO982712L (ro)
NZ (1) NZ318843A (ro)
OA (1) OA10694A (ro)
PE (1) PE25698A1 (ro)
PL (1) PL197306B1 (ro)
RO (1) RO121382B1 (ro)
RU (1) RU2160731C2 (ro)
SK (1) SK75498A3 (ro)
TN (1) TNSN96153A1 (ro)
TW (1) TW414787B (ro)
UY (1) UY24401A1 (ro)
WO (1) WO1997022584A1 (ro)
YU (1) YU49486B (ro)
ZA (1) ZA9610533B (ro)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999036405A1 (en) 1998-01-16 1999-07-22 Eisai Co., Ltd. Process for production of donepezil derivative
IL125809A (en) * 1998-08-17 2005-08-31 Finetech Lab Ltd Process and intermediates for production of donepezil and related compounds
US7148354B2 (en) * 2002-07-24 2006-12-12 Dr. Reddy's Laboratories Limited Process for preparation of donepezil
IL150982A (en) 2002-07-30 2007-02-11 Ori Lerman Process for making Donafzil
IL151253A0 (en) * 2002-08-14 2003-04-10 Finetech Lab Ltd Process for production of highly pure donepezil hydrochloride
US6953856B2 (en) 2003-02-12 2005-10-11 Usv, Limited Process for the preparation of 1-benzyl-4-(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCI)
US6649765B1 (en) 2003-02-12 2003-11-18 Usv Limited, Bsd Marg. Process for the preparation of 1-benzyl-4(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCL)
US20070129549A1 (en) * 2003-03-21 2007-06-07 Yatendra Kumar Stable lamotrigine pharmaceutical compositions and processes for their preparation
WO2004099142A1 (en) * 2003-05-05 2004-11-18 Ranbaxy Laboratories Limited Hydrobromide salt of benzyl-piperidylmethyl-indanone and its polymorphs
AU2003247158A1 (en) 2003-07-01 2005-01-21 Hetero Drugs Limited Preparation of intermediates for acetyl cholinesterase inhibitors
CN1280273C (zh) * 2003-11-05 2006-10-18 天津和美生物技术有限公司 合成多奈哌齐及其衍生物的方法
WO2006035433A2 (en) 2004-09-29 2006-04-06 Chemagis Ltd. Use of purified donepezil maleate for preparing pharmaceutically pure amorphous donepezil hydrochloride
CN100436416C (zh) * 2005-07-29 2008-11-26 西南合成制药股份有限公司 盐酸多奈哌齐合成工艺
GB0515803D0 (en) 2005-07-30 2005-09-07 Pliva Hrvatska D O O Intermediate compounds
AR057910A1 (es) 2005-11-18 2007-12-26 Synthon Bv Proceso para preparar donepezilo
ES2354737T3 (es) * 2006-01-04 2011-03-17 Cipla Limited Procedimiento y producto intermedio para la preparación de donepezylo.
CN101626688A (zh) 2006-12-11 2010-01-13 雷维瓦药品公司 茚满酮基胆碱酯酶抑制剂的组合物、合成和使用方法
WO2013078608A1 (en) 2011-11-29 2013-06-06 Ziqiang Gu Donepezil pamoate and methods of making and using the same
US10357486B2 (en) 2013-08-16 2019-07-23 Universiteit Maastricht Treatment of cognitive impairment with PDE4 inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
FR2642069B1 (fr) * 1989-01-20 1991-04-12 Rhone Poulenc Sante Nouveaux derives du benzopyranne, leur preparation et les compositions pharmaceutiques qui les contiennent
DE4439822A1 (de) * 1994-11-08 1996-08-29 Bayer Ag Verfahren zur Herstellung von Benzyl-piperidylmethyl-indanonen

Also Published As

Publication number Publication date
IS4752A (is) 1998-05-22
TNSN96153A1 (fr) 2005-03-15
IL124452A0 (en) 1998-12-06
JP3066083B2 (ja) 2000-07-17
CZ180898A3 (cs) 1999-05-12
IL136420A0 (en) 2001-06-14
AR004368A1 (es) 1998-11-04
NO982712D0 (no) 1998-06-12
AP9600892A0 (en) 1997-01-31
MX9804820A (es) 1998-10-31
MA24032A1 (fr) 1997-07-01
CA2237647A1 (en) 1997-06-26
HRP960592A2 (en) 1998-06-30
CO4750831A1 (es) 1999-03-31
NZ318843A (en) 2000-01-28
IL136421A0 (en) 2001-06-14
ZA9610533B (en) 1998-06-15
PL197306B1 (pl) 2008-03-31
PL327512A1 (en) 1998-12-21
KR20000064387A (ko) 2000-11-06
HUP9904275A3 (en) 2001-05-28
HUP9904275A2 (hu) 2000-05-28
YU49486B (sh) 2006-08-17
AP708A (en) 1998-12-04
AU7092596A (en) 1997-07-14
PE25698A1 (es) 1998-05-21
RU2160731C2 (ru) 2000-12-20
NO982712L (no) 1998-06-12
RO121382B1 (ro) 2007-04-30
WO1997022584A1 (en) 1997-06-26
GT199600092A (es) 1998-05-12
DZ2141A1 (fr) 2002-07-23
BG102525A (en) 1999-05-31
UY24401A1 (es) 1997-06-09
TW414787B (en) 2000-12-11
BR9612018A (pt) 1999-02-17
YU66096A (en) 1999-11-22
EP0883607A1 (en) 1998-12-16
SK75498A3 (en) 1999-08-06
JPH11500756A (ja) 1999-01-19
OA10694A (en) 2001-05-04
AU716462B2 (en) 2000-02-24

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