HK99795A - Process for preparing 4-acyloxy-3-hydroxyethyl-azetidinones - Google Patents
Process for preparing 4-acyloxy-3-hydroxyethyl-azetidinonesInfo
- Publication number
- HK99795A HK99795A HK99795A HK99795A HK99795A HK 99795 A HK99795 A HK 99795A HK 99795 A HK99795 A HK 99795A HK 99795 A HK99795 A HK 99795A HK 99795 A HK99795 A HK 99795A
- Authority
- HK
- Hong Kong
- Prior art keywords
- azetidinones
- acyloxy
- hydroxyethyl
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
- C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/94—Saccharomyces
- Y10S435/942—Saccharomyces cerevisiae
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH168387 | 1987-05-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK99795A true HK99795A (en) | 1995-06-30 |
Family
ID=4216154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK99795A HK99795A (en) | 1987-05-04 | 1995-06-22 | Process for preparing 4-acyloxy-3-hydroxyethyl-azetidinones |
Country Status (9)
Country | Link |
---|---|
US (2) | US4927507A (fr) |
EP (1) | EP0290385B1 (fr) |
JP (2) | JP2520447B2 (fr) |
CA (1) | CA1335971C (fr) |
DE (1) | DE3875373D1 (fr) |
DK (2) | DK170856B1 (fr) |
ES (1) | ES2045180T3 (fr) |
HK (1) | HK99795A (fr) |
IE (1) | IE62804B1 (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0279781A3 (fr) * | 1987-02-17 | 1989-07-26 | Ciba-Geigy Ag | Procédé pour la préparation de 4-acétoxy-3-hydroxyéthyl-azétidinone |
US5274188A (en) * | 1987-05-04 | 1993-12-28 | Ciba-Geigy Corporation | Process for the manufacture of 4-acyloxy-3-hydroxyethyl-azetidinones |
JPH0623150B2 (ja) * | 1988-11-15 | 1994-03-30 | 高砂香料工業株式会社 | 光学活性3−ヒドロキシブタン酸類の製造方法 |
US5204460A (en) * | 1988-11-29 | 1993-04-20 | Takasago International Corporation | Ruthenium catalyzed process for preparing 4-acetoxyazetidinones |
US5241064A (en) * | 1989-10-02 | 1993-08-31 | Fujisawa Pharmaceutical Co., Ltd. | Enzymatic process for preparing optically active 3-substituted azetidinones |
JP2640986B2 (ja) * | 1990-11-08 | 1997-08-13 | 高砂香料工業株式会社 | (1′r,3s)―3―(1′―ヒドロキシエチル)―アゼチジン―2―オン又はその誘導体の製造法 |
JP2787248B2 (ja) * | 1990-11-30 | 1998-08-13 | 高砂香料工業株式会社 | 4―アセトキシアゼチジノン類の製造方法 |
US5420337A (en) * | 1992-11-12 | 1995-05-30 | E. R. Squibb & Sons, Inc. | Enzymatic reduction method for the preparation of compounds useful for preparing taxanes |
US5631363A (en) * | 1992-11-13 | 1997-05-20 | Tanabe Seiyaku Co., Ltd. | Azetidinone compound and process for preparation thereof |
US5346983A (en) * | 1993-05-28 | 1994-09-13 | Hoechst Celanese Corporation | Substituted phenyl compounds and processes for preparing the same |
US5602272A (en) * | 1994-06-21 | 1997-02-11 | Bristol-Myers Squibb Company | Reduction and resolution methods for the preparation of compounds useful as intemediates for preparing taxanes |
KR19990058545A (ko) * | 1997-12-30 | 1999-07-15 | 유현식 | 메틸(2에스,3알)-2-(엔-벤조일아미노)메티래-3-히드록시부타노에이트의 합성방법 |
JP4854136B2 (ja) * | 2001-06-20 | 2012-01-18 | 和光純薬工業株式会社 | ハロアルキルスルホン化合物及びビニルスルホン化合物の製造方法 |
KR100451413B1 (ko) * | 2001-12-28 | 2004-10-06 | 한국과학기술연구원 | 클루이베로마이시스 마르시아누스의 카르보닐 환원효소를이용한 카르보닐 화합물의 환원반응 |
KR100522133B1 (ko) | 2002-01-26 | 2005-10-18 | 한국과학기술연구원 | 클루이베로마이세스 마르시아누스로부터 분리 및 정제된 카르보닐 환원효소 및 그 제조 방법 |
JP5090910B2 (ja) * | 2005-07-20 | 2012-12-05 | 株式会社カネカ | 光学活性2−(n−置換アミノメチル)−3−ヒドロキシ酪酸エステル類の製造方法 |
CN1940079B (zh) * | 2006-09-08 | 2010-10-13 | 鲁南制药集团股份有限公司 | 利用酵母细胞不对称合成(2s,3s)-2-苯甲酰氨甲基-3-羟基丁酸酯系列化合物 |
WO2009046153A1 (fr) * | 2007-10-01 | 2009-04-09 | Codexis, Inc. | Polypeptides de cétoréductase pour la production d'azétidinone |
US8426178B2 (en) * | 2008-08-27 | 2013-04-23 | Codexis, Inc. | Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
WO2010025287A2 (fr) * | 2008-08-27 | 2010-03-04 | Codexis, Inc. | Polypeptides cétoréductases pour la production de 3-aryl-3-hydroxypropanamine à partir de a 3-aryl-3-cétopropanamine |
SI2329014T1 (sl) | 2008-08-29 | 2015-01-30 | Codexis, Inc. | Polipeptidi ketoreduktaze za stereoselektivno produkcijo (4s)-3(5s)-5(4-fluorofenil)-5-hidroksipentanoil)-4-fenil-1,3-oksazolidin -2-ona |
WO2011022548A2 (fr) | 2009-08-19 | 2011-02-24 | Codexis, Inc. | Polypeptides de kétoréductase pour la préparation de phényléphrine |
EP2566497B1 (fr) | 2010-05-04 | 2015-07-29 | Codexis, Inc. | Biocatalyseurs pour la synthèse d'ézétimibe |
CN103045504B (zh) * | 2012-12-05 | 2014-06-04 | 浙江工业大学 | 微生物催化制备(2s, 3r)-2-苯甲酰氨甲基-3-羟基丁酸酯及菌株 |
CN105624125B (zh) * | 2014-11-26 | 2020-03-17 | 上海弈柯莱生物医药科技有限公司 | 醛酮还原酶及其在合成(2s,3r)-2-苯甲酰氨甲基-3-羟基丁酸酯中的应用 |
CN113528592B (zh) * | 2021-06-08 | 2022-08-19 | 复旦大学 | 酶催化的(2s,3r)-2-取代氨基甲基-3-羟基丁酸酯的合成方法 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3681333A (en) * | 1967-07-24 | 1972-08-01 | Allied Chem | Process for the preparation of cyclic iminoethers |
US4138400A (en) * | 1975-12-20 | 1979-02-06 | Hoechst Aktiengesellschaft | Omega-alkoxy derivatives of lactams |
US4138408A (en) * | 1975-12-20 | 1979-02-06 | Hoechst Aktiengesellschaft | ω-Alkoxy derivatives of lactams and process for their manufacture |
US4400323A (en) * | 1979-07-23 | 1983-08-23 | Merck & Co., Inc. | 3-[1-Hydroxyethyl]-4-carboxymethyl-azetidin-2-one |
US4467107A (en) * | 1981-04-08 | 1984-08-21 | Merck & Co., Inc. | 1-Hydroxyethyl-2-amino pentanedioic acid derivatives |
US4473502A (en) * | 1981-04-08 | 1984-09-25 | Merck & Co., Inc. | Synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid |
CA1190236A (fr) | 1981-10-23 | 1985-07-09 | Edward J.J. Grabowski | Synthese d'un antibiotique |
EP0106652B1 (fr) * | 1982-10-13 | 1988-01-27 | Sumitomo Pharmaceuticals Company, Limited | Dérivés de bêta-lactame et leur production |
GB8321004D0 (en) * | 1983-08-04 | 1983-09-07 | Erba Farmitalia | Azetidinones |
US4656165A (en) | 1983-09-02 | 1987-04-07 | Ciba-Geigy Corporation | Aminomethyl penem compounds |
DE3340006A1 (de) * | 1983-11-04 | 1985-05-23 | Hans Rudolf Prof. Dipl.-Chem. Dr. 8000 München Pfaendler | Verfahren zur herstellung von azetidin-2-onen |
US4596677A (en) * | 1984-04-06 | 1986-06-24 | Bristol-Myers Company | Anhydropenicillin intermediates |
CA1256443A (fr) * | 1984-07-05 | 1989-06-27 | Takehisa Ohashi | Methode de preparation de derives de la 4-acetoxy- 3-hydroxyethylazetidin-2-one |
EP0171064B1 (fr) | 1984-08-06 | 1995-07-12 | Fujisawa Pharmaceutical Co., Ltd. | Dérivés de l'azétidinone et procédé pour leur préparation |
EP0181831B1 (fr) | 1984-10-01 | 1993-08-25 | Ciba-Geigy Ag | Procédé de préparation d'acyloxyazétidinones optiquement actives |
EP0180398A1 (fr) * | 1984-10-26 | 1986-05-07 | The Regents Of The University Of California | Synthèse de bêta-lactame |
US4892961A (en) * | 1985-07-31 | 1990-01-09 | Sumitomo Pharmaceuticals Company, Limited | Amino acid derivatives, and their production |
DE3688960D1 (de) | 1985-09-11 | 1993-10-07 | Ciba Geigy | Synthese von Beta-Lactamverbindungen. |
US4882429A (en) * | 1986-03-03 | 1989-11-21 | Schering Corporation | Stereospecific preparation of (3S,4R,5R)-3-(1-hydroxyethyl)-4-benzoyloxy-azeridinones from L-(-)-theonine |
-
1988
- 1988-04-26 ES ES88810264T patent/ES2045180T3/es not_active Expired - Lifetime
- 1988-04-26 DE DE8888810264T patent/DE3875373D1/de not_active Expired - Lifetime
- 1988-04-26 EP EP88810264A patent/EP0290385B1/fr not_active Expired - Lifetime
- 1988-04-27 US US07/186,547 patent/US4927507A/en not_active Expired - Lifetime
- 1988-05-02 JP JP63107766A patent/JP2520447B2/ja not_active Expired - Lifetime
- 1988-05-02 CA CA000565639A patent/CA1335971C/fr not_active Expired - Fee Related
- 1988-05-03 DK DK238988A patent/DK170856B1/da not_active IP Right Cessation
- 1988-05-03 IE IE132788A patent/IE62804B1/en not_active IP Right Cessation
-
1990
- 1990-03-09 US US07/491,145 patent/US5064761A/en not_active Expired - Lifetime
-
1995
- 1995-01-10 DK DK002795A patent/DK171985B1/da not_active IP Right Cessation
- 1995-06-22 HK HK99795A patent/HK99795A/xx not_active IP Right Cessation
-
1996
- 1996-01-30 JP JP8013813A patent/JP2711244B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK170856B1 (da) | 1996-02-12 |
DK2795A (da) | 1995-01-10 |
US5064761A (en) | 1991-11-12 |
JP2711244B2 (ja) | 1998-02-10 |
IE62804B1 (en) | 1995-03-08 |
JPS63297360A (ja) | 1988-12-05 |
US4927507A (en) | 1990-05-22 |
DK238988A (da) | 1988-11-05 |
ES2045180T3 (es) | 1994-01-16 |
CA1335971C (fr) | 1995-06-20 |
EP0290385B1 (fr) | 1992-10-21 |
DK171985B1 (da) | 1997-09-08 |
IE881327L (en) | 1988-11-04 |
DK238988D0 (da) | 1988-05-03 |
EP0290385A1 (fr) | 1988-11-09 |
JPH09104678A (ja) | 1997-04-22 |
DE3875373D1 (de) | 1992-11-26 |
JP2520447B2 (ja) | 1996-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20080425 |