HK886A - Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid;a mixture of the salts of these d and 1 acids;a pharmaceutical composition containing a salt of the d acid;a salt of the d acid - Google Patents

Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid;a mixture of the salts of these d and 1 acids;a pharmaceutical composition containing a salt of the d acid;a salt of the d acid

Info

Publication number
HK886A
HK886A HK8/86A HK886A HK886A HK 886 A HK886 A HK 886A HK 8/86 A HK8/86 A HK 8/86A HK 886 A HK886 A HK 886A HK 886 A HK886 A HK 886A
Authority
HK
Hong Kong
Prior art keywords
acid
salt
naphthyl
methoxy
resolution
Prior art date
Application number
HK8/86A
Other languages
English (en)
Inventor
Percy George Holton
Original Assignee
Syntex Pharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26734026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK886(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/097,118 external-priority patent/US4246193A/en
Application filed by Syntex Pharma Int filed Critical Syntex Pharma Int
Publication of HK886A publication Critical patent/HK886A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/50—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK8/86A 1979-07-06 1986-01-02 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid;a mixture of the salts of these d and 1 acids;a pharmaceutical composition containing a salt of the d acid;a salt of the d acid HK886A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5525879A 1979-07-06 1979-07-06
US06/097,118 US4246193A (en) 1979-11-26 1979-11-26 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Publications (1)

Publication Number Publication Date
HK886A true HK886A (en) 1986-01-10

Family

ID=26734026

Family Applications (1)

Application Number Title Priority Date Filing Date
HK8/86A HK886A (en) 1979-07-06 1986-01-02 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid;a mixture of the salts of these d and 1 acids;a pharmaceutical composition containing a salt of the d acid;a salt of the d acid

Country Status (27)

Country Link
EP (1) EP0022529B1 (pt)
JP (2) JPS63313749A (pt)
KR (1) KR830000769B1 (pt)
AR (1) AR225927A1 (pt)
AU (1) AU544963B2 (pt)
CA (1) CA1135717A (pt)
CZ (1) CZ277725B6 (pt)
DD (1) DD153367A5 (pt)
DE (3) DE3025448A1 (pt)
DK (2) DK156051C (pt)
ES (1) ES8105691A1 (pt)
FR (2) FR2472557A1 (pt)
GB (1) GB2054579B (pt)
GR (1) GR68796B (pt)
HK (1) HK886A (pt)
IE (1) IE50000B1 (pt)
IL (1) IL60498A (pt)
IN (1) IN152737B (pt)
IT (1) IT1130490B (pt)
MY (1) MY8600452A (pt)
NZ (1) NZ194237A (pt)
PH (4) PH15674A (pt)
PL (1) PL133439B1 (pt)
PT (1) PT71486A (pt)
RO (1) RO80655B (pt)
SK (1) SK278340B6 (pt)
YU (1) YU42673B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168387B (it) * 1981-04-01 1987-05-20 Alfa Farmaceutici Spa Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
ZA828453B (en) * 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
IT1196197B (it) * 1984-07-23 1988-11-10 Ravizza Spa Procedimento per la risoluzione dell'acido (+)(-) 2-(2'-(p-fluorofenil)--5'-benzossazolil)-propionico
GB9121279D0 (en) * 1991-10-08 1991-11-20 Cerestar Holding Bv Process for the production of aminopolyols
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
KR100678287B1 (ko) * 2005-06-23 2007-02-02 한미약품 주식회사 클로피도그렐의 제조방법 및 이에 사용되는 중간체
KR101170537B1 (ko) * 2010-01-11 2012-08-01 김창운 해수의 자연순환이 가능한 내륙 내 바다양식 수조

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
DE1668654B2 (de) * 1967-01-13 1976-11-04 Syntex Corp., Panama 2-(6'-substituierte-2'-naphthyl)- propionsaeuren und -derivate, ihre herstellung und sie enthaltende arzneimittel
ZA70809B (en) * 1969-03-24 1971-09-29 Syntex Corp Amine salts of 2-(6'-methoxy-2'-naphthyl)propionic acids and processes for the preparation thereof
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
US3904683A (en) * 1972-08-10 1975-09-09 Syntex Corp Process for the resolution of d- and 1-2-(6-methoxy-2-naphthyl) propionic acid
CS222255B2 (en) * 1977-03-08 1983-06-24 Boots Co Ltd Method of increasing the portion of the deisred anantiometer in the acid component of the 2-arylpropion acid
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.

Also Published As

Publication number Publication date
RO80655A (ro) 1983-04-29
PH16328A (en) 1983-09-05
CS477480A3 (en) 1992-11-18
NZ194237A (en) 1984-05-31
SK278340B6 (en) 1996-12-04
JPH0454B2 (pt) 1992-01-06
PL225474A1 (pt) 1981-03-27
DK156051B (da) 1989-06-19
FR2472557B1 (pt) 1984-04-20
RO80655B (ro) 1983-04-30
FR2472557A1 (fr) 1981-07-03
PT71486A (en) 1980-08-01
JPS63313749A (ja) 1988-12-21
GR68796B (pt) 1982-02-18
DE3063969D1 (en) 1983-08-04
FR2470108A1 (fr) 1981-05-29
AU544963B2 (en) 1985-06-27
CZ277725B6 (en) 1993-04-14
MY8600452A (en) 1986-12-31
JPH0321535B2 (pt) 1991-03-22
GB2054579B (en) 1983-06-22
ES493126A0 (es) 1981-06-16
YU174380A (en) 1984-04-30
IL60498A (en) 1984-06-29
EP0022529A1 (en) 1981-01-21
DK239988A (da) 1988-05-03
FR2470108B1 (pt) 1984-04-20
CA1135717A (en) 1982-11-16
IT1130490B (it) 1986-06-11
PL133439B1 (en) 1985-06-29
JPH0249749A (ja) 1990-02-20
DK239988D0 (da) 1988-05-03
DE3051036C2 (pt) 1988-03-31
YU42673B (en) 1988-10-31
IE50000B1 (en) 1986-01-22
DE3025448C2 (pt) 1987-05-21
DE3025448A1 (de) 1981-01-15
AR225927A1 (es) 1982-05-14
ES8105691A1 (es) 1981-06-16
DK156051C (da) 1989-11-06
DD153367A5 (de) 1982-01-06
DK289080A (da) 1981-01-07
IT8068053A0 (it) 1980-07-03
PH15674A (en) 1983-03-11
IL60498A0 (en) 1980-09-16
PH16431A (en) 1983-10-03
GB2054579A (en) 1981-02-18
AU6012180A (en) 1981-01-15
EP0022529B1 (en) 1983-06-29
KR830000769B1 (ko) 1983-04-11
IN152737B (pt) 1984-03-24
IE801396L (en) 1981-01-06
PH16432A (en) 1983-10-03

Similar Documents

Publication Publication Date Title
GB2093693B (en) Pharmaceutical preparations for topical application which contain salts of alkanecarboxylic acids novel carboxylic acid salts and the production thereof
HK886A (en) Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid;a mixture of the salts of these d and 1 acids;a pharmaceutical composition containing a salt of the d acid;a salt of the d acid
GB2021583B (en) Process for preparing 2-(6'-methoxy-2'naphthyl propionic acid
GR60385B (en) New propargyl-2-phenylamino-imidazolines-(2),salts thereof by addition of their acids,pharmaceutical mediums containing the above and process for their preparation
DE3071736D1 (en) Process for preparing 2-nitro-5-(substituted-phenoxy) benzoic acids and salts thereof
YU139985A (en) Process for preparation of (d)-2-(6-metoxi-2-naphtile) propionic acid or its pharmaceutically acceptable salts
DE2964790D1 (en) Hypoglycemic phenylpropynylamino benzoic acids, their salts, pharmaceutical compositions containing said compounds and their application
DE3162513D1 (en) Process for the optical resolution of mixtures of d- and l-2-(6-methoxy-2-naphthyl)-propionic acids, the cinchonidine salt of d-2-(6-methoxy-2-naphthyl)-propionic acid and the preparation thereof
GB2019393B (en) Process for the preparation of 2-(3-benzoylphenyl)-propionic acid
YU85378A (en) Process for preparing 2-(3-benzoylphenyl)-propionic acid
IL48465A0 (en) New 6',2-(2'-arylchromonyl)propionic acids and their salts,their preparation and pharmaceutical compositions containing them
ZA803924B (en) Process for the resolution of d, 1 2-(6-methoxy-2-naphthyl) proprionic acid
IL52966A0 (en) Novel 2-(phenylalkylhydrazono)-propionic acid derivatives process for their preparation and pharmaceutical compositions containing the same
YU39370B (en) Process for the preparation of 2-(3-benzoylphenyl)-propionic acid
ZA793541B (en) Substituted 2-phenylamino-imidazoline-(2)derivatives and their acid addition salts,processes for their preparation and pharmaceutical compositions containing these compounds
IL70934A0 (en) Salts of d 2-(6-methoxy-2-naphthyl)propionic acid with n-substituted d-glucamine,their preparation and pharmaceutical compositions containing them
IL70934A (en) Salts of d 2-(6-methoxy-2-naphthyl)propionic acid with n-substituted d-glucamine,their preparation and pharmaceutical compositions containing them
PT67381A (en) A process for preparing a mixture of 2-ketogulonic and 2-ketogluconic acid or salts of these acids
AU491101B2 (en) A process for the preparation of 2-(4-isobutyl-phenyl)-propiohydroxamic acid
HRP950186B1 (en) Process for the preparation of 2-(4-isobutyl-phenyl)-propionic acid
YU283179A (en) Process for preparing 2-(3-benzoylphenyl)propionic acid
PH11631A (en) Process for preparing a pharmaceutical suspension containing as the active ingredient aluminum salt of 2-(3-phenoxyphenyl)propionic acid
YU40755B (en) Process for preparing 2-(4-isobutylphenyl)-propionic acid
AU8563475A (en) A process for the preparation of 2-(4-isobutyl-phenyl)-propiohydroxamic acid

Legal Events

Date Code Title Description
PE Patent expired