HK8280A - 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity - Google Patents

5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity

Info

Publication number
HK8280A
HK8280A HK82/80A HK8280A HK8280A HK 8280 A HK8280 A HK 8280A HK 82/80 A HK82/80 A HK 82/80A HK 8280 A HK8280 A HK 8280A HK 8280 A HK8280 A HK 8280A
Authority
HK
Hong Kong
Prior art keywords
benzene ring
ring substituted
substituted benzimidazole
carbamate derivatives
anthelmintic activity
Prior art date
Application number
HK82/80A
Other languages
English (en)
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26981949&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK8280(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of HK8280A publication Critical patent/HK8280A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK82/80A 1972-12-29 1980-03-06 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity HK8280A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31929972A 1972-12-29 1972-12-29
US417963A US3929821A (en) 1972-12-29 1973-11-21 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives

Publications (1)

Publication Number Publication Date
HK8280A true HK8280A (en) 1980-03-14

Family

ID=26981949

Family Applications (1)

Application Number Title Priority Date Filing Date
HK82/80A HK8280A (en) 1972-12-29 1980-03-06 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity

Country Status (25)

Country Link
US (1) US3929821A (de)
JP (1) JPS5939428B2 (de)
AR (2) AR216037A1 (de)
AT (1) AT332883B (de)
BR (1) BR7310296D0 (de)
CH (2) CH613955A5 (de)
CS (1) CS187390B2 (de)
DE (3) DE2366070C2 (de)
DK (1) DK137329B (de)
ES (2) ES421927A1 (de)
FR (1) FR2212150B1 (de)
GB (2) GB1455728A (de)
HK (1) HK8280A (de)
HU (1) HU169272B (de)
IE (1) IE40046B1 (de)
IL (1) IL43860A (de)
IN (1) IN138644B (de)
IT (1) IT1046097B (de)
MY (1) MY8000273A (de)
NL (1) NL169738C (de)
PL (1) PL95987B1 (de)
RO (1) RO67150A (de)
SE (1) SE414402B (de)
SU (1) SU727143A3 (de)
YU (2) YU36706B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002640A (en) * 1972-12-29 1977-01-11 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4258198A (en) * 1973-05-29 1981-03-24 Smithkline Corporation 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles
DE2441201C2 (de) * 1974-08-28 1986-08-07 Hoechst Ag, 6230 Frankfurt Anthelminthisch wirksame 2-Carbalkoxyamino-5(6)-phenyl-sulfonyloxy-benzimidazole und Verfahren zu ihrer Herstellung
DE2441202C2 (de) * 1974-08-28 1986-05-28 Hoechst Ag, 6230 Frankfurt 2-Carbalkoxyamino-benzimidazolyl-5(6)-sulfonsäure-phenylester, Verfahren zu ihrer Herstellung und diese enthaltende anthelmintische Mittel
US4086235A (en) * 1976-04-12 1978-04-25 Syntex (U.S.A.) Inc. 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4046908A (en) * 1976-07-16 1977-09-06 E. R. Squibb & Sons, Inc. Benzimidazole derivatives, compositions thereof and method of use as anthelmintics
USRE30990E (en) * 1976-07-16 1982-07-06 E. R. Squibb & Sons, Inc. Benzimidazole derivatives, compositions thereof and method of use as anthelmintics
US4166858A (en) * 1976-08-13 1979-09-04 Burroughs Wellcome Co. Method and composition for treating fluke infections
IE45741B1 (en) * 1976-08-13 1982-11-17 Wellcome Found An anthelmintic ether combination
FR2362116A1 (fr) * 1976-08-20 1978-03-17 Oreal Metaphenylenediamines et compositions tinctoriales les contenant
US4093732A (en) * 1977-02-17 1978-06-06 E. R. Squibb & Sons, Inc. Sulfoxide derivatives of benzimidazoles
IT1076022B (it) * 1977-04-20 1985-04-22 Montedison Spa Benzimidazolcarbammati antielmintici
IT1107749B (it) * 1977-10-06 1985-11-25 Montedison Spa Benzimidazolcarbammato particolarmente attivo contro i parassiti gastroenterici e polmonari
US4152522A (en) * 1978-01-03 1979-05-01 Ethyl Corporation Process for the preparation of 2-benzimidazole carbamates
US4156006A (en) * 1978-01-09 1979-05-22 E. R. Squibb & Sons, Inc. Vinyl sulfide derivatives of benzimidazoles
US4136174A (en) * 1978-01-18 1979-01-23 E. R. Squibb & Sons, Inc. Benzimidazolecarbamates and method
JPS54104837A (en) * 1978-02-03 1979-08-17 Nippon Denso Co Ltd Controller of copying machines
US4145431A (en) * 1978-02-16 1979-03-20 E. R. Squibb & Sons, Inc. Method of treating helminthiasis by parenteral administration of sulfide- and sulfoxide-derivatives of benzimidazoles
US4154846A (en) * 1978-06-16 1979-05-15 E. R. Squibb & Sons, Inc. Substituted thio-, sulfinyl-, and sulfonyl-alkyl benzimidazole carbamates
US4174400A (en) * 1978-09-13 1979-11-13 Merck & Co., Inc. Anthelmintic benzimidazoles
DE2845537A1 (de) * 1978-10-19 1980-04-30 Bayer Ag Benzimidazolylcarbamidsaeureester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
IT1100788B (it) * 1978-12-06 1985-09-28 Montedison Spa Benzimidazol-carbammati
DD147539A5 (de) * 1978-12-06 1981-04-08 Montedison Spa Herstellung von in 5(6)-stellung substituierten benzimidazol-carbamaten
US4198422A (en) * 1979-05-17 1980-04-15 E. R. Squibb & Sons, Inc. Substituted 2,3-naphthimidazole carbamates and method
EP0028455A1 (de) * 1979-10-12 1981-05-13 Imperial Chemical Industries Plc 5-Phenylselenobenzimidazolderivate, ihre Herstellung und sie enthaltende anthelminthische oder fasziolizide Zusammensetzungen
HU182763B (hu) * 1979-10-19 1984-03-28 Chinoin Gyogyszer Es Vegyeszet Eljárás 5(6)-alkiltio-benzimidazolil-alkil-karbamátok előállítására
IL61232A (en) * 1979-10-19 1985-09-29 Chinoin Gyogyszer Es Vegyeszet Process for the preparation of 2-amino(or alkoxycarbonylamino)-5(6)-thiocyanato(or thiol)benzimidazole derivatives
US4599428A (en) * 1979-10-19 1986-07-08 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt Process for the preparation of 5(6)-thio substituted benzimidazoles
US4299837A (en) 1979-12-05 1981-11-10 Montedison S.P.A. Anthelmintic benzimidazole-carbamates
DE3719783A1 (de) * 1987-06-13 1988-12-22 Hoechst Ag Verfahren zur herstellung von 5-phenylsulfinyl-1h-2-(methoxycarbonylamino)- benzimidazol
GB9205368D0 (en) * 1992-03-12 1992-04-22 Pfizer Ltd Benzimidozole anthelmintic agents
US6593466B1 (en) 1999-07-07 2003-07-15 Isis Pharmaceuticals, Inc. Guanidinium functionalized nucleotides and precursors thereof
ATE467637T1 (de) * 2005-07-28 2010-05-15 Intervet Int Bv Neue benzimidazol(thio)carbamate mit antiparasitischer wirkung und ihre synthese
JP5406022B2 (ja) * 2006-06-12 2014-02-05 スミス アンド ネフュー インコーポレーテッド 脛骨切除システム、方法、及び装置
KR101403135B1 (ko) 2006-06-14 2014-06-19 인터벳 인터내셔널 비.브이. 벤지미다졸 카르바메이트 및 폴리솔베이트를 포함하는 현탁물
CN102241635A (zh) * 2011-04-28 2011-11-16 江苏宝众宝达药业有限公司 一种苯并咪唑类驱虫药苯硫咪唑的制备方法
CN102863392A (zh) * 2012-10-18 2013-01-09 江苏宝众宝达药业有限公司 一种奥芬达唑生产过程中大幅减少溶剂使用量的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2933502A (en) * 1958-02-12 1960-04-19 Du Pont Benzimidazolone derivatives
US2933504A (en) * 1959-08-10 1960-04-19 Du Pont Derivatives of polyalkoxycarbonyl imine
US3010968A (en) * 1959-11-25 1961-11-28 Du Pont Process for manufacture of certain alkyl esters of benzimidazole carbamic acids
BE666795A (de) * 1964-08-04 1966-01-13
US3506767A (en) * 1965-08-06 1970-04-14 Geigy Chem Corp Benzimidazole compositions and methods of use
US3401171A (en) * 1966-03-11 1968-09-10 Smithkline Corp 2-amidobenzimidazoles
CH456236A (de) * 1966-05-06 1968-07-15 Agripat Sa Verfahren zum Schützen textiler Keratinfasermaterialien vor Insektenfrass und Mittel zur Durchführung dieses Verfahrens
US3480642A (en) * 1967-03-22 1969-11-25 Smithkline Corp Process for producing 2-carbalkoxyaminobenzimidazoles
CH490010A (de) * 1967-10-26 1970-05-15 Ciba Geigy Schädlingsbekämpfungsmittel
US3562290A (en) * 1967-11-07 1971-02-09 Du Pont Process for making 2-benzimidazolecarbamic acid alkyl esters
FR2059938A1 (en) * 1969-03-14 1971-06-11 Aries Robert 1-haloalk(en)yl sulphenyl-2-aryloxycarbon-yl -
US3657267A (en) * 1969-06-20 1972-04-18 Janssen Pharmaceutica Nv Benzimidazole carbamates
US3714180A (en) * 1970-08-12 1973-01-30 Squibb & Sons Inc Sulfonyl benzimidazoles
US3694455A (en) * 1970-11-19 1972-09-26 Smith Kline French Lab Acyloxyalkyl amidobenzimidazoles
US3720686A (en) * 1971-04-01 1973-03-13 Squibb & Sons Inc Mercaptobenzimidazole derivatives

Also Published As

Publication number Publication date
CH613955A5 (de) 1979-10-31
DK137329B (da) 1978-02-20
BR7310296D0 (pt) 1974-09-24
IN138644B (de) 1976-03-06
US3929821A (en) 1975-12-30
YU64180A (en) 1983-04-30
GB1455728A (en) 1976-11-17
IL43860A0 (en) 1974-03-14
IL43860A (en) 1977-05-31
ATA1075173A (de) 1976-02-15
CS187390B2 (en) 1979-01-31
ES421927A1 (es) 1977-01-01
IE40046B1 (en) 1979-02-28
AT332883B (de) 1976-10-25
DE2363351C2 (de) 1987-03-12
IE40046L (en) 1974-06-29
DE2366069C2 (de) 1987-06-11
DK137329C (de) 1978-07-24
DE2363351A1 (de) 1974-07-11
YU337173A (en) 1981-11-13
AR221816A1 (es) 1981-03-31
ES445257A1 (es) 1977-10-01
GB1456497A (en) 1976-11-24
JPS5939428B2 (ja) 1984-09-22
SE414402B (sv) 1980-07-28
IT1046097B (it) 1980-06-30
FR2212150B1 (de) 1977-01-28
AU6367473A (en) 1975-06-19
PL95987B1 (pl) 1977-11-30
DE2366070C2 (de) 1987-06-11
NL169738C (nl) 1982-08-16
RO67150A (ro) 1980-12-30
MY8000273A (en) 1980-12-31
YU36706B (en) 1984-08-31
AR216037A1 (es) 1979-11-30
FR2212150A1 (de) 1974-07-26
NL7317797A (de) 1974-07-02
SU727143A3 (ru) 1980-04-05
DE2366069A1 (de) 1977-11-10
JPS505518A (de) 1975-01-21
CH608006A5 (de) 1978-12-15
NL169738B (nl) 1982-03-16
YU40868B (en) 1986-06-30
HU169272B (de) 1976-10-28

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