HK65886A - Enzyme derivatives,and their preparation - Google Patents

Enzyme derivatives,and their preparation

Info

Publication number
HK65886A
HK65886A HK658/86A HK65886A HK65886A HK 65886 A HK65886 A HK 65886A HK 658/86 A HK658/86 A HK 658/86A HK 65886 A HK65886 A HK 65886A HK 65886 A HK65886 A HK 65886A
Authority
HK
Hong Kong
Prior art keywords
preparation
enzyme derivatives
enzyme
derivatives
Prior art date
Application number
HK658/86A
Other languages
English (en)
Inventor
Richard Anthony Godwin Smith
John Gordon Winchester
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of HK65886A publication Critical patent/HK65886A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3153—Streptokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK658/86A 1979-11-05 1986-09-04 Enzyme derivatives,and their preparation HK65886A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7938279 1979-11-05

Publications (1)

Publication Number Publication Date
HK65886A true HK65886A (en) 1986-09-12

Family

ID=10508982

Family Applications (1)

Application Number Title Priority Date Filing Date
HK658/86A HK65886A (en) 1979-11-05 1986-09-04 Enzyme derivatives,and their preparation

Country Status (18)

Country Link
US (1) US4808405A (da)
EP (1) EP0028489B1 (da)
JP (1) JPS5678590A (da)
AR (1) AR224786A1 (da)
CA (1) CA1174621A (da)
CS (2) CS391991A3 (da)
DE (1) DE3065190D1 (da)
DK (1) DK158994C (da)
ES (1) ES496586A0 (da)
GR (1) GR72121B (da)
HK (1) HK65886A (da)
HU (1) HU185223B (da)
IE (1) IE50174B1 (da)
IL (1) IL61408A (da)
NL (1) NL930029I2 (da)
NO (1) NO163867C (da)
NZ (1) NZ195469A (da)
ZA (1) ZA806641B (da)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
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EP0091240B1 (en) * 1982-04-07 1985-12-27 Beecham Group Plc Enzyme derivatives, process for preparing them and pharmaceutical compositions containing them
WO1984001960A1 (en) * 1982-11-11 1984-05-24 Beecham Group Plc Pharmaceutically active compounds
GB8400653D0 (en) * 1984-01-11 1984-02-15 Beecham Group Plc Conjugates
GB8430253D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
US5231006A (en) * 1986-10-16 1993-07-27 Behringwerke Aktiengesellschaft Method for the determination of plasminogen
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
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EP0467987A4 (en) * 1989-05-01 1992-07-08 The University Of Notre Dame Du Lac Methods and materials for expression of human plasminogen in a eukaryotic cell system
EP0397366A1 (en) * 1989-05-09 1990-11-14 The Board Of Regents Of The University Of Oklahoma Hybrid streptokinases with fibrin binding domains and methods for the synthesis of same
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US5190756A (en) * 1989-12-01 1993-03-02 Genentech, Inc. Methods and materials for expression of human plasminogen variant
US5087572A (en) * 1989-12-01 1992-02-11 Genentech, Inc. Dna encoding human plasminogen modified at the cleavage site
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US6458360B1 (en) 1990-04-25 2002-10-01 The Johns Hopkins University Soluble complement regulatory molecules
US5187069A (en) * 1990-08-06 1993-02-16 Henry Ford Health System Active site labelling of plasminogen
AU1873092A (en) * 1991-04-09 1992-11-17 Brigham And Women's Hospital Chimeric molecule with plasminogen activator activity and affinity for atherosclerotic plaques
US5520912A (en) * 1993-07-02 1996-05-28 Immuno Aktiengesellschaft Prevention and treatment of ischemic events and reperfusion injury resulting therefrom using lys-plasminogen
DE4411143C2 (de) * 1994-03-30 1996-08-01 Immuno Ag Thrombosemittel
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US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
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JPS5325775A (en) * 1976-08-24 1978-03-09 Miller Fluid Power Corp Module type fluid flow control element
US4082612A (en) * 1976-09-24 1978-04-04 Michael Reese Research Foundation Plasminogen activator complex
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions

Also Published As

Publication number Publication date
DE3065190D1 (en) 1983-11-10
US4808405A (en) 1989-02-28
AU6401180A (en) 1981-05-14
ES8204467A1 (es) 1982-05-01
AU534017B2 (en) 1983-12-22
NO163867B (no) 1990-04-23
JPS5678590A (en) 1981-06-27
IL61408A0 (en) 1980-12-31
NO163867C (no) 1990-08-01
JPH0316114B2 (da) 1991-03-04
DK158994B (da) 1990-08-13
NL930029I2 (nl) 1993-12-01
IE50174B1 (en) 1986-02-19
IE802277L (en) 1981-05-05
NZ195469A (en) 1984-05-31
EP0028489B1 (en) 1983-10-05
ES496586A0 (es) 1982-05-01
GR72121B (da) 1983-09-16
CS391191A3 (en) 1992-08-12
CS391991A3 (en) 1992-06-17
HU185223B (en) 1984-12-28
DK158994C (da) 1991-01-07
ZA806641B (en) 1981-10-28
CA1174621A (en) 1984-09-18
EP0028489A1 (en) 1981-05-13
AR224786A1 (es) 1982-01-15
NL930029I1 (nl) 1993-06-01
DK468880A (da) 1981-05-06
NO803304L (no) 1981-05-06
IL61408A (en) 1983-10-31

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