ZA806641B - Enzyme derivatives - Google Patents

Enzyme derivatives

Info

Publication number
ZA806641B
ZA806641B ZA00806641A ZA806641A ZA806641B ZA 806641 B ZA806641 B ZA 806641B ZA 00806641 A ZA00806641 A ZA 00806641A ZA 806641 A ZA806641 A ZA 806641A ZA 806641 B ZA806641 B ZA 806641B
Authority
ZA
South Africa
Prior art keywords
enzyme derivatives
enzyme
derivatives
Prior art date
Application number
ZA00806641A
Other languages
English (en)
Inventor
R Smith
J Winchester
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of ZA806641B publication Critical patent/ZA806641B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3153—Streptokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00806641A 1979-11-05 1980-10-29 Enzyme derivatives ZA806641B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7938279 1979-11-05

Publications (1)

Publication Number Publication Date
ZA806641B true ZA806641B (en) 1981-10-28

Family

ID=10508982

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00806641A ZA806641B (en) 1979-11-05 1980-10-29 Enzyme derivatives

Country Status (18)

Country Link
US (1) US4808405A (xx)
EP (1) EP0028489B1 (xx)
JP (1) JPS5678590A (xx)
AR (1) AR224786A1 (xx)
CA (1) CA1174621A (xx)
CS (2) CS391191A3 (xx)
DE (1) DE3065190D1 (xx)
DK (1) DK158994C (xx)
ES (1) ES8204467A1 (xx)
GR (1) GR72121B (xx)
HK (1) HK65886A (xx)
HU (1) HU185223B (xx)
IE (1) IE50174B1 (xx)
IL (1) IL61408A (xx)
NL (1) NL930029I2 (xx)
NO (1) NO163867C (xx)
NZ (1) NZ195469A (xx)
ZA (1) ZA806641B (xx)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
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DE3361610D1 (en) * 1982-04-07 1986-02-06 Beecham Group Plc Enzyme derivatives, process for preparing them and pharmaceutical compositions containing them
EP0125269A1 (en) * 1982-11-11 1984-11-21 Beecham Group Plc Pharmaceutically active compounds
GB8400653D0 (en) * 1984-01-11 1984-02-15 Beecham Group Plc Conjugates
GB8430253D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
US5231006A (en) * 1986-10-16 1993-07-27 Behringwerke Aktiengesellschaft Method for the determination of plasminogen
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
JPH0296536A (ja) * 1988-09-29 1990-04-09 Green Cross Corp:The プラスミノゲン乾燥製剤
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EP0397366A1 (en) * 1989-05-09 1990-11-14 The Board Of Regents Of The University Of Oklahoma Hybrid streptokinases with fibrin binding domains and methods for the synthesis of same
ATE135200T1 (de) * 1989-05-17 1996-03-15 Res Corp Technologies Inc Verfahren und zusammensetzung zur thrombosebehandlung beim säugetier
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US5190756A (en) * 1989-12-01 1993-03-02 Genentech, Inc. Methods and materials for expression of human plasminogen variant
US5087572A (en) * 1989-12-01 1992-02-11 Genentech, Inc. Dna encoding human plasminogen modified at the cleavage site
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US5520912A (en) * 1993-07-02 1996-05-28 Immuno Aktiengesellschaft Prevention and treatment of ischemic events and reperfusion injury resulting therefrom using lys-plasminogen
DE4411143C2 (de) * 1994-03-30 1996-08-01 Immuno Ag Thrombosemittel
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US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
US7910597B2 (en) * 2006-11-28 2011-03-22 Shire Llc Substituted quinazolines
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US20090130017A1 (en) * 2007-11-19 2009-05-21 Searete Llc Targeted short-lived drug delivery
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AP2014007621A0 (en) 2011-11-11 2014-05-31 Pfizer 2-Thiopyrimidinones
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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178368A (en) * 1971-09-30 1979-12-11 Behringwerke Aktiengesellschaft Method for the treatment of thromboembolism
JPS5325775A (en) * 1976-08-24 1978-03-09 Miller Fluid Power Corp Module type fluid flow control element
US4082612A (en) * 1976-09-24 1978-04-04 Michael Reese Research Foundation Plasminogen activator complex
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions

Also Published As

Publication number Publication date
EP0028489A1 (en) 1981-05-13
IE50174B1 (en) 1986-02-19
EP0028489B1 (en) 1983-10-05
IE802277L (en) 1981-05-05
NO163867C (no) 1990-08-01
NO163867B (no) 1990-04-23
NL930029I2 (nl) 1993-12-01
IL61408A0 (en) 1980-12-31
JPS5678590A (en) 1981-06-27
HU185223B (en) 1984-12-28
NO803304L (no) 1981-05-06
NL930029I1 (nl) 1993-06-01
GR72121B (xx) 1983-09-16
DE3065190D1 (en) 1983-11-10
DK468880A (da) 1981-05-06
CS391991A3 (en) 1992-06-17
JPH0316114B2 (xx) 1991-03-04
CA1174621A (en) 1984-09-18
IL61408A (en) 1983-10-31
ES496586A0 (es) 1982-05-01
AR224786A1 (es) 1982-01-15
NZ195469A (en) 1984-05-31
AU534017B2 (en) 1983-12-22
DK158994C (da) 1991-01-07
US4808405A (en) 1989-02-28
ES8204467A1 (es) 1982-05-01
CS391191A3 (en) 1992-08-12
AU6401180A (en) 1981-05-14
HK65886A (en) 1986-09-12
DK158994B (da) 1990-08-13

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