|
JPH05236966A
(ja)
*
|
1991-04-25 |
1993-09-17 |
Chugai Pharmaceut Co Ltd |
ヒトインターロイキン−６レセプターに対するマウスモノクローナル抗体の可変領域をコードするｄｎａ
|
|
ES2134212T3
(es)
*
|
1991-04-25 |
1999-10-01 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo humano reconstituido contra el receptor de la interleuquina 6 humano.
|
|
FR2694767B1
(fr)
*
|
1992-08-13 |
1994-10-21 |
Innotherapie Lab Sa |
Anticorps monoclonaux anti-IL6R, et leurs applications.
|
|
AU7967294A
(en)
*
|
1993-10-06 |
1995-05-01 |
Board Of Regents, The University Of Texas System |
A monoclonal anti-human il-6 receptor antibody
|
|
US8017121B2
(en)
|
1994-06-30 |
2011-09-13 |
Chugai Seiyaku Kabushika Kaisha |
Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
|
|
US5763211A
(en)
*
|
1994-09-14 |
1998-06-09 |
Progenitor, Inc. |
Isolated nucleic acid encoding Hu-B1.219, a novel human hematopoietin
|
|
US5856098A
(en)
*
|
1994-09-14 |
1999-01-05 |
Progenitor, Inc. |
Detection of a leptin receptor variant
|
|
US6355237B1
(en)
|
1994-09-14 |
2002-03-12 |
Progenitor, Inc. |
Methods for using the obese gene and its gene product to stimulate hematopoietic development
|
|
US6451523B1
(en)
|
1994-09-14 |
2002-09-17 |
Interneuron Pharmaceuticals, Inc. |
Detection of a leptin receptor variant and methods for regulating obesity
|
|
US5912123A
(en)
*
|
1994-09-14 |
1999-06-15 |
Progenitor, Inc. |
Detection of the leptin receptor in reproductive organs and methods for regulating reproductive biology
|
|
US5643748A
(en)
|
1994-09-14 |
1997-07-01 |
Progenitor, Inc. |
HU-B1.219, a novel human hematopoietin receptor
|
|
CN101601861A
(zh)
*
|
1994-10-07 |
2009-12-16 |
中外制药株式会社 |
以il-6拮抗剂作为有效成分治疗慢性类风湿性关节炎
|
|
WO1996012503A1
(fr)
*
|
1994-10-21 |
1996-05-02 |
Chugai Seiyaku Kabushiki Kaisha |
Remede contre des maladies provoquees par la production d'il-6
|
|
JP3458512B2
(ja)
|
1995-02-23 |
2003-10-20 |
東ソー株式会社 |
骨密度の変動推定方法又は骨そしょう症の診断方法及びこれに用いる試薬キット
|
|
AU1833197A
(en)
*
|
1996-01-18 |
1997-08-11 |
Progenitor, Inc. |
Detection of a leptin receptor variant and methods for regulating obesity
|
|
AU3276297A
(en)
|
1996-06-27 |
1998-01-14 |
Chugai Seiyaku Kabushiki Kaisha |
Remedies for myeloma to be used together with nitrogen mustard antitumor agents
|
|
ES2477996T3
(es)
|
2000-08-11 |
2014-07-18 |
Chugai Seiyaku Kabushiki Kaisha |
Preparaciones estabilizadas que contienen un anticuerpo
|
|
DK1334731T3
(da)
|
2000-10-25 |
2008-05-26 |
Chugai Pharmaceutical Co Ltd |
Forebyggende eller terapeutisk middel mod psoriasis omfattende anti-IL-6-receptorantistof som aktiv bestanddel
|
|
UA80091C2
(en)
|
2001-04-02 |
2007-08-27 |
Chugai Pharmaceutical Co Ltd |
Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
|
|
GB2401040A
(en)
|
2003-04-28 |
2004-11-03 |
Chugai Pharmaceutical Co Ltd |
Method for treating interleukin-6 related diseases
|
|
AR046290A1
(es)
|
2003-10-17 |
2005-11-30 |
Chugai Pharmaceutical Co Ltd |
Agente terapeutico para el mesotelioma
|
|
CN101330930B
(zh)
|
2005-10-21 |
2011-11-23 |
中外制药株式会社 |
心脏病治疗剂
|
|
AR057582A1
(es)
|
2005-11-15 |
2007-12-05 |
Nat Hospital Organization |
Agentes para suprimir la induccion de linfocitos t citotoxicos
|
|
KR20080084818A
(ko)
|
2005-11-25 |
2008-09-19 |
각고호우징 게이오기주크 |
전립선암 치료제
|
|
AU2007208678B2
(en)
|
2006-01-27 |
2013-01-10 |
Chugai Seiyaku Kabushiki Kaisha |
Therapeutic agents for diseases involving choroidal neovascularization
|
|
JP5754875B2
(ja)
|
2006-04-07 |
2015-07-29 |
国立大学法人大阪大学 |
筋再生促進剤
|
|
US8080248B2
(en)
|
2006-06-02 |
2011-12-20 |
Regeneron Pharmaceuticals, Inc. |
Method of treating rheumatoid arthritis with an IL-6R antibody
|
|
SI2041177T1
(sl)
*
|
2006-06-02 |
2012-03-30 |
Regeneron Pharma |
Visoko afinitetna protitelesa za humani IL receptor
|
|
CN101528778A
(zh)
*
|
2006-08-18 |
2009-09-09 |
埃博灵克斯股份有限公司 |
用于治疗与il-6-介导的信号传导相关的疾病和病症的针对il-6r的氨基酸序列以及包括其的多肽
|
|
CA2666599A1
(en)
*
|
2006-08-18 |
2008-02-21 |
Ablynx N.V. |
Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of diseases and disorders associated with il-6-mediated signalling
|
|
WO2008071685A1
(en)
*
|
2006-12-13 |
2008-06-19 |
Ablynx N.V. |
Polypeptides specific for complexes involved in receptor-mediated signaling, such as the il-6/il-6 receptor complex
|
|
EP3246045A1
(de)
|
2007-07-26 |
2017-11-22 |
Osaka University |
Therapeutische mittel für entzündliche augenerkrankung mit interleukin-6-rezeptor-inhibitor als wirkstoff
|
|
KR101601986B1
(ko)
|
2007-10-02 |
2016-03-17 |
추가이 세이야쿠 가부시키가이샤 |
인터류킨 6 수용체 저해제를 유효 성분으로 하는 이식편대숙주병 치료제
|
|
US8034344B2
(en)
|
2008-05-13 |
2011-10-11 |
Novimmune S.A. |
Anti-IL-6/IL-6R antibodies and methods of use thereof
|
|
US10717781B2
(en)
|
2008-06-05 |
2020-07-21 |
National Cancer Center |
Neuroinvasion inhibitor
|
|
SG174862A1
(en)
|
2009-04-10 |
2011-11-28 |
Ablynx Nv |
Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorder
|
|
EP2417162A2
(de)
|
2009-04-10 |
2012-02-15 |
Ablynx N.V. |
Verbesserte, gegen il-6r gerichtete amiinosäuresequenzen und polypeptide, die diese enthalten, zur behandlung von krankheiten und erkrankungen, die mit il-6r in zusammenhang stehen
|
|
TWI523661B
(zh)
|
2009-07-31 |
2016-03-01 |
Shin Maeda |
Anti-IL-6 receptor antibody in the manufacture of inhibitors of metastatic inhibition of lung cancer metastasis to the liver
|
|
CN102596995B
(zh)
|
2009-10-26 |
2015-08-12 |
弗·哈夫曼-拉罗切有限公司 |
用于生产糖基化免疫球蛋白的方法
|
|
JO3417B1
(ar)
|
2010-01-08 |
2019-10-20 |
Regeneron Pharma |
الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r
|
|
SI2578231T1
(sl)
|
2010-05-28 |
2023-01-31 |
Chugai Seiyaku Kabushiki Kaisha |
Okrepljen protitumorski T celični odzivnik
|
|
EP2747782B1
(de)
|
2011-09-23 |
2018-01-17 |
Ablynx NV |
Verlängerte inhibition der interleukin-6-vermittelten signalisierung
|
|
TWI589299B
(zh)
|
2011-10-11 |
2017-07-01 |
再生元醫藥公司 |
用於治療類風濕性關節炎之組成物及其使用方法
|
|
US10782290B2
(en)
|
2013-06-11 |
2020-09-22 |
National Center Of Neurology And Psychiatry |
Method for predicting post-therapy prognosis of relapsing-remitting multiple sclerosis (RRMS) patient, and method for determining applicability of novel therapy
|
|
KR102248581B1
(ko)
|
2013-07-04 |
2021-05-06 |
에프. 호프만-라 로슈 아게 |
혈청 샘플 중 항-약물 항체를 검출하기 위한 간섭-억제된 면역분석
|
|
DE202014010499U1
(de)
|
2013-12-17 |
2015-10-20 |
Kymab Limited |
Targeting von humaner PCSK9 zur Cholesterinbehandlung
|
|
US9017678B1
(en)
|
2014-07-15 |
2015-04-28 |
Kymab Limited |
Method of treating rheumatoid arthritis using antibody to IL6R
|
|
EP3209327A1
(de)
|
2014-10-21 |
2017-08-30 |
Ablynx N.V. |
Behandlung von il-6r-bedingten erkrankungen
|
|
US11851486B2
(en)
|
2017-05-02 |
2023-12-26 |
National Center Of Neurology And Psychiatry |
Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils
|
|
WO2019151418A1
(ja)
|
2018-01-31 |
2019-08-08 |
元一 加藤 |
Ｉｌ－６阻害剤を含有する喘息の治療剤
|
|
WO2020160465A1
(en)
|
2019-01-31 |
2020-08-06 |
Sanofi Biotechnology |
Anti-il-6 receptor antibody for treating juvenile idiopathic arthritis
|
|
EP4263602A1
(de)
|
2020-12-18 |
2023-10-25 |
Ablynx N.V. |
Polypeptide mit variablen immunglobulin-einzeldomänen zum targeting von il-6 und tnf-alpha
|