HK14094A - Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same - Google Patents

Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same

Info

Publication number
HK14094A
HK14094A HK140/94A HK14094A HK14094A HK 14094 A HK14094 A HK 14094A HK 140/94 A HK140/94 A HK 140/94A HK 14094 A HK14094 A HK 14094A HK 14094 A HK14094 A HK 14094A
Authority
HK
Hong Kong
Prior art keywords
pyrazoles
diaryl
synthesizing
substituted
same
Prior art date
Application number
HK140/94A
Other languages
English (en)
Inventor
Michael Paul Wachter
Michael Paul Ferro
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of HK14094A publication Critical patent/HK14094A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/84Unsaturated compounds containing keto groups containing six membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/88Unsaturated compounds containing keto groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK140/94A 1986-05-29 1994-02-24 Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same HK14094A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86799686A 1986-05-29 1986-05-29
US07/042,661 US4826868A (en) 1986-05-29 1987-04-29 1,5-Diaryl-3-substituted pyrazoles pharmaceutical compositions and use

Publications (1)

Publication Number Publication Date
HK14094A true HK14094A (en) 1994-03-04

Family

ID=26719497

Family Applications (1)

Application Number Title Priority Date Filing Date
HK140/94A HK14094A (en) 1986-05-29 1994-02-24 Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same

Country Status (21)

Country Link
US (1) US4826868A (de)
EP (1) EP0248594B1 (de)
JP (1) JP2512751B2 (de)
KR (1) KR960007163B1 (de)
CN (1) CN1028227C (de)
AU (1) AU596844B2 (de)
CA (1) CA1337122C (de)
DE (2) DE3788244T2 (de)
DK (1) DK170202B1 (de)
ES (1) ES2059377T3 (de)
FI (1) FI94340C (de)
HK (1) HK14094A (de)
HU (1) HU221300B1 (de)
IE (1) IE63856B1 (de)
IL (1) IL82671A0 (de)
LU (1) LU90829I2 (de)
NL (1) NL300057I2 (de)
NO (2) NO172236C (de)
NZ (1) NZ220353A (de)
PH (1) PH25126A (de)
PT (1) PT84964B (de)

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US5117054A (en) * 1991-09-26 1992-05-26 Ortho Pharmaceutical Corporation N-hydroxy, N-methyl propanamides
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US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
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Also Published As

Publication number Publication date
NL300057I1 (nl) 2001-12-01
NO172236B (no) 1993-03-15
HU221300B1 (en) 2002-09-28
PT84964A (en) 1987-06-01
EP0248594A2 (de) 1987-12-09
DE3788244D1 (de) 1994-01-05
FI872379A (fi) 1987-11-30
DK273587A (da) 1987-11-30
CN1028227C (zh) 1995-04-19
NZ220353A (en) 1989-05-29
FI94340C (fi) 1995-08-25
IE63856B1 (en) 1995-06-14
EP0248594B1 (de) 1993-11-24
HUT68247A (en) 1995-06-28
JPS6322080A (ja) 1988-01-29
NO2001016I1 (no) 2001-10-01
DE10199049I1 (de) 2002-01-10
ES2059377T3 (es) 1994-11-16
IE871403L (en) 1987-11-29
PH25126A (en) 1991-02-19
FI94340B (fi) 1995-05-15
DE3788244T2 (de) 1994-04-14
NO872228L (no) 1987-11-30
AU7360887A (en) 1987-12-10
IL82671A0 (en) 1987-11-30
PT84964B (pt) 1990-02-08
US4826868A (en) 1989-05-02
CN87103953A (zh) 1987-12-09
DK273587D0 (da) 1987-05-27
DE10199049I2 (de) 2003-01-09
NL300057I2 (nl) 2002-01-02
DK170202B1 (da) 1995-06-12
NO172236C (no) 1993-06-23
JP2512751B2 (ja) 1996-07-03
LU90829I2 (fr) 2001-11-12
KR960007163B1 (ko) 1996-05-29
FI872379A0 (fi) 1987-05-28
NO872228D0 (no) 1987-05-27
KR870011100A (ko) 1987-12-21
EP0248594A3 (en) 1988-11-17
AU596844B2 (en) 1990-05-17
CA1337122C (en) 1995-09-26

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Effective date: 20070527