HK1259103A1 - 用於在细菌细胞培养物中生产多糖的培养基和发酵方法 - Google Patents

用於在细菌细胞培养物中生产多糖的培养基和发酵方法

Info

Publication number
HK1259103A1
HK1259103A1 HK19101603.6A HK19101603A HK1259103A1 HK 1259103 A1 HK1259103 A1 HK 1259103A1 HK 19101603 A HK19101603 A HK 19101603A HK 1259103 A1 HK1259103 A1 HK 1259103A1
Authority
HK
Hong Kong
Prior art keywords
culture medium
concentration
total
culture
yeast extract
Prior art date
Application number
HK19101603.6A
Other languages
English (en)
Chinese (zh)
Inventor
Sunil Gururao DESAI
Michael Allen Hanson
Jonathan Patrick KINROSS
Daniel R Lasko
Scott Ellis LOMBERK
Jason Arnold Lotvin
Sujata Kaushikbhai PATEL-BROWN
Weiqiang SUN
Peter Anthony TOMASELLO
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of HK1259103A1 publication Critical patent/HK1259103A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK19101603.6A 2015-11-17 2016-11-10 用於在细菌细胞培养物中生产多糖的培养基和发酵方法 HK1259103A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562256347P 2015-11-17 2015-11-17
US62/256347 2015-11-17
US201662413051P 2016-10-26 2016-10-26
US62/413051 2016-10-26
PCT/IB2016/056780 WO2017085602A1 (en) 2015-11-17 2016-11-10 Media and fermentation methods for producing polysaccharides in bacterial cell culture

Publications (1)

Publication Number Publication Date
HK1259103A1 true HK1259103A1 (zh) 2019-11-22

Family

ID=57394621

Family Applications (1)

Application Number Title Priority Date Filing Date
HK19101603.6A HK1259103A1 (zh) 2015-11-17 2016-11-10 用於在细菌细胞培养物中生产多糖的培养基和发酵方法

Country Status (13)

Country Link
US (3) US10947494B2 (https=)
EP (1) EP3377613A1 (https=)
JP (3) JP7311966B2 (https=)
KR (1) KR102069988B1 (https=)
CN (1) CN108473945A (https=)
AU (1) AU2016357567B2 (https=)
BR (1) BR112018008864A8 (https=)
CA (2) CA3005308C (https=)
HK (1) HK1259103A1 (https=)
IL (2) IL319202A (https=)
MX (2) MX385736B (https=)
RU (2) RU2021135165A (https=)
WO (1) WO2017085602A1 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI815599B (zh) 2011-04-22 2023-09-11 美商惠氏有限責任公司 與難養芽胞梭菌（Ｃｌｏｓｔｒｉｄｉｕｍ ｄｉｆｆｉｃｉｌｅ）之突變毒素有關之組成物及彼之方法
PT2837680T (pt) * 2011-07-01 2020-04-17 Amgen Inc Cultura celular de mamífero
BR122016023101B1 (pt) * 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
BR112019003992A2 (pt) 2016-09-02 2019-05-28 Sanofi Pasteur Inc vacina contra neisseria meningitidis
EP4656208A3 (en) 2017-01-31 2026-03-04 Merck Sharp & Dohme LLC Methods for making polysaccharide-protein conjugates
JP7680185B2 (ja) 2017-02-24 2025-05-20 メルク・シャープ・アンド・ドーム・エルエルシー 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強
MX394767B (es) 2017-09-07 2025-03-24 Merck Sharp & Dohme Llc Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina transportadora.
MX394768B (es) 2017-09-07 2025-03-21 Merck Sharp & Dohme Llc Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina.
ES3058336T3 (es) 2017-12-06 2026-03-10 Merck Sharp & Dohme Llc Composiciones que comprenden conjugados polisacárido-proteína de Streptococcus pneumoniae y métodos de uso de los mismos
EP3787673A4 (en) 2018-04-30 2022-04-27 Merck Sharp & Dohme Corp. Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates
US12144855B2 (en) 2018-04-30 2024-11-19 Merck Sharp & Dohme Llc Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates from lyospheres
EP3788143B1 (en) 2018-04-30 2023-06-28 Merck Sharp & Dohme LLC Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide
CN113423815A (zh) * 2018-12-06 2021-09-21 创赏有限公司 非动物来源培养基上的细菌生长
CA3122085A1 (en) * 2018-12-11 2020-06-18 Erbi Biosystems, Inc. Methods of manufacturing cell based products using small volume perfusion processes
CR20210333A (es) 2018-12-19 2021-08-18 Merck Sharp & Dohme Composiciones que comprenden conjugados de polisacárido de streptococcus pneumoniae con proteína y sus métodos de uso
CN111254103B (zh) * 2019-11-19 2023-06-02 河南省生物工程技术研究中心 一种非洲猪瘟基因工程疫苗高密度发酵补料培养基及发酵工艺
US20230200424A1 (en) * 2020-04-20 2023-06-29 Evonik Operations Gmbh Compositions comprising cys-peptides
WO2021255690A2 (en) 2020-06-19 2021-12-23 Pfizer Inc. Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof
CN114015622A (zh) * 2021-12-14 2022-02-08 塔里木大学 无乳链球菌培养基及其制备方法
WO2023131588A1 (en) * 2022-01-05 2023-07-13 Nordmark Pharma Gmbh Culture medium for cultivating hathewaya histolytica (or clostridium histolyticum) and the production of one or more proteases
CN114181872B (zh) * 2022-01-07 2023-11-24 北京大北农科技集团股份有限公司 一种屎肠球菌高密度发酵培养方法
KR102866798B1 (ko) * 2022-12-27 2025-10-01 (주)진성유니텍 살모넬라균 증균을 위한 최소배지 및 이를 이용한 살모넬라균 증균방법
KR102864280B1 (ko) * 2022-12-27 2025-09-26 (주)진성유니텍 포도상구균 증균을 위한 최소배지 및 이를 이용한 포도상구균 증균방법
CN117821342B (zh) * 2024-02-29 2024-06-04 北京民海生物科技有限公司 一种14型肺炎链球菌的发酵方法
KR102894728B1 (ko) 2024-11-27 2025-12-08 한국콜마주식회사 피지 생성 억제 효능, 모공 개선 효능 및 피부 장벽 강화 효능이 우수한 흑효모 발효물 및 이의 제조방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801054A (en) * 1996-09-19 1998-09-01 The United States Of America As Represented By The Secretary Of The Air Force Cell culture vessel with self-maintained atmosphere
DE69838383T2 (de) 1997-05-28 2008-06-05 Novartis Vaccines And Diagnostics S.R.L. Kulturmedium mit sojabohnenextrakt als aminosäuren-quelle und ohne proteinkomplexe tierischen ursprungs
US7115385B2 (en) * 2001-08-02 2006-10-03 North Carolina State University Media and methods for cultivation of microorganisms
TWI384069B (zh) 2004-08-27 2013-02-01 Pfizer Ireland Pharmaceuticals 多胜肽之製法
US7472101B2 (en) 2005-07-12 2008-12-30 Tibco Software Inc. Inferential state machines
GB0522303D0 (en) * 2005-11-01 2005-12-07 Chiron Srl Culture method
US7491517B2 (en) 2006-07-19 2009-02-17 Jeeri R Reddy Method of producing meningococcal meningitis vaccine for Neisseria meningitidis serotypes A,C,Y, and W-135
SI2078071T1 (sl) * 2006-11-08 2015-05-29 Wyeth Llc Racionalno zasnovana gojišča za celično kulturo
GB0818453D0 (en) * 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
WO2011151841A1 (en) * 2010-05-31 2011-12-08 Panacea Biotec Limited Fermentation process for streptococcus pneumoniae
CN103052717B (zh) * 2011-05-17 2015-01-14 中国食品发酵工业研究院 一种工业化生产玉米降压活性肽的方法
CN104080904B (zh) * 2011-12-15 2017-06-30 血清研究所印度私人有限公司 培养细菌以提高荚膜多糖产率的新方法
EP2647715A1 (en) * 2012-04-03 2013-10-09 Nomad Bioscience GmbH Agrobacterium for transient transfection of whole plants
GB201211256D0 (en) 2012-06-25 2012-08-08 Glaxosmithkline Biolog Sa Fermentation process
WO2014080423A2 (en) * 2012-11-21 2014-05-30 Serum Institute Of India Ltd. Production of high yields of bacterial polysaccharides

Also Published As

Publication number Publication date
JP7814142B2 (ja) 2026-02-16
KR102069988B1 (ko) 2020-01-23
IL259404B1 (en) 2025-04-01
CA3005308C (en) 2022-01-04
IL259404B2 (en) 2025-08-01
MX385736B (es) 2025-03-18
BR112018008864A2 (pt) 2018-11-06
JP2022017529A (ja) 2022-01-25
US20190292513A1 (en) 2019-09-26
MX2018006063A (es) 2018-09-17
US10947494B2 (en) 2021-03-16
RU2018118035A3 (https=) 2019-12-18
RU2018118035A (ru) 2019-12-18
CN108473945A (zh) 2018-08-31
JP7311966B2 (ja) 2023-07-20
AU2016357567A1 (en) 2018-05-17
IL259404A (en) 2018-07-31
JP2018533366A (ja) 2018-11-15
RU2761633C2 (ru) 2021-12-13
JP2024037949A (ja) 2024-03-19
US20210180008A1 (en) 2021-06-17
KR20180073699A (ko) 2018-07-02
RU2021135165A (ru) 2021-12-29
MX2021010518A (es) 2021-10-01
CA3138763A1 (en) 2017-05-26
AU2016357567B2 (en) 2020-05-07
IL319202A (en) 2025-04-01
EP3377613A1 (en) 2018-09-26
WO2017085602A1 (en) 2017-05-26
CA3005308A1 (en) 2017-05-26
BR112018008864A8 (pt) 2019-02-26
US20260008994A1 (en) 2026-01-08

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