HK1222793A1 - 用於抑制含布羅莫結構域的蛋白質的方法和組合物 - Google Patents

用於抑制含布羅莫結構域的蛋白質的方法和組合物

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Publication number
HK1222793A1
HK1222793A1 HK16110964.3A HK16110964A HK1222793A1 HK 1222793 A1 HK1222793 A1 HK 1222793A1 HK 16110964 A HK16110964 A HK 16110964A HK 1222793 A1 HK1222793 A1 HK 1222793A1
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HK
Hong Kong
Prior art keywords
bromodomain
inhibition
compositions
methods
containing proteins
Prior art date
Application number
HK16110964.3A
Other languages
English (en)
Inventor
‧凡卡亞拉帕提
‧吉岡
‧斯特羅唯爾
‧帕迪亞
Original Assignee
Convergene Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Convergene Llc filed Critical Convergene Llc
Publication of HK1222793A1 publication Critical patent/HK1222793A1/zh

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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
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HK16110964.3A 2013-03-14 2016-09-19 用於抑制含布羅莫結構域的蛋白質的方法和組合物 HK1222793A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361781988P 2013-03-14 2013-03-14
PCT/US2014/025289 WO2014159837A1 (en) 2013-03-14 2014-03-13 Methods and compositions for inhibition of bromodomain-containing proteins

Publications (1)

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HK1222793A1 true HK1222793A1 (zh) 2017-07-14

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HK16110964.3A HK1222793A1 (zh) 2013-03-14 2016-09-19 用於抑制含布羅莫結構域的蛋白質的方法和組合物

Country Status (12)

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US (3) US9695179B2 (zh)
EP (1) EP2968360B1 (zh)
JP (1) JP6464139B2 (zh)
KR (1) KR20150135359A (zh)
CN (1) CN105407894A (zh)
AU (1) AU2014244426B2 (zh)
BR (1) BR112015022417A2 (zh)
CA (1) CA2905451A1 (zh)
EA (1) EA201591746A1 (zh)
HK (1) HK1222793A1 (zh)
MX (1) MX367420B (zh)
WO (1) WO2014159837A1 (zh)

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JP5992049B2 (ja) 2011-11-01 2016-09-14 レスバーロジックス コーポレイション 置換されたキナゾリノンのための経口速放性製剤
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