MX367420B - Metodos y composiciones para inhibicion de proteinas que contienen bromodominio. - Google Patents

Metodos y composiciones para inhibicion de proteinas que contienen bromodominio.

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Publication number
MX367420B
MX367420B MX2015012478A MX2015012478A MX367420B MX 367420 B MX367420 B MX 367420B MX 2015012478 A MX2015012478 A MX 2015012478A MX 2015012478 A MX2015012478 A MX 2015012478A MX 367420 B MX367420 B MX 367420B
Authority
MX
Mexico
Prior art keywords
bromodomain
methods
inhibition
containing proteins
compositions
Prior art date
Application number
MX2015012478A
Other languages
English (en)
Other versions
MX2015012478A (es
Inventor
Vankayalapati Hariprasad
Yoshioka Makoto
William Strovel Jeffrey
Khimchand Padia Janak
Original Assignee
Convergene Llc
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Filing date
Publication date
Application filed by Convergene Llc filed Critical Convergene Llc
Publication of MX2015012478A publication Critical patent/MX2015012478A/es
Publication of MX367420B publication Critical patent/MX367420B/es

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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

La presente invención se refiere a compuestos que se unen a, y de otro modo modulan la actividad de proteínas que contienen bromodominio, a procesos para preparar estos compuestos, a composiciones farmacéuticas que contienen estos compuestos, y a métodos para usar estos compuestos para tratar una amplia variedad de condiciones y trastornos.
MX2015012478A 2013-03-14 2014-03-13 Metodos y composiciones para inhibicion de proteinas que contienen bromodominio. MX367420B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361781988P 2013-03-14 2013-03-14
PCT/US2014/025289 WO2014159837A1 (en) 2013-03-14 2014-03-13 Methods and compositions for inhibition of bromodomain-containing proteins

Publications (2)

Publication Number Publication Date
MX2015012478A MX2015012478A (es) 2016-08-08
MX367420B true MX367420B (es) 2019-08-21

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MX2015012478A MX367420B (es) 2013-03-14 2014-03-13 Metodos y composiciones para inhibicion de proteinas que contienen bromodominio.

Country Status (12)

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US (3) US9695179B2 (es)
EP (1) EP2968360B1 (es)
JP (1) JP6464139B2 (es)
KR (1) KR20150135359A (es)
CN (1) CN105407894A (es)
AU (1) AU2014244426B2 (es)
BR (1) BR112015022417A2 (es)
CA (1) CA2905451A1 (es)
EA (1) EA201591746A1 (es)
HK (1) HK1222793A1 (es)
MX (1) MX367420B (es)
WO (1) WO2014159837A1 (es)

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