HK1221718A1 - 具有快速皮膚和生物膜穿透速度的非甾體抗炎藥的前藥及其新的醫藥用途 - Google Patents

具有快速皮膚和生物膜穿透速度的非甾體抗炎藥的前藥及其新的醫藥用途

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Publication number
HK1221718A1
HK1221718A1 HK16109927.1A HK16109927A HK1221718A1 HK 1221718 A1 HK1221718 A1 HK 1221718A1 HK 16109927 A HK16109927 A HK 16109927A HK 1221718 A1 HK1221718 A1 HK 1221718A1
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HK
Hong Kong
Prior art keywords
nsaias
pro
drugs
high skin
penetration rates
Prior art date
Application number
HK16109927.1A
Other languages
English (en)
Inventor
于崇曦
徐麗娜
Original Assignee
Yu Chongxi
Techfields Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yu Chongxi, Techfields Inc filed Critical Yu Chongxi
Publication of HK1221718A1 publication Critical patent/HK1221718A1/zh

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    • C07—ORGANIC CHEMISTRY
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    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
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    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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HK16109927.1A 2007-06-04 2016-08-18 具有快速皮膚和生物膜穿透速度的非甾體抗炎藥的前藥及其新的醫藥用途 HK1221718A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200780053229.XA CN101687792B (zh) 2007-06-04 2007-06-04 具有快速皮肤和生物膜穿透速度的非甾体抗炎药的前药及其医药用途
PCT/IB2007/052090 WO2008149181A1 (en) 2007-06-04 2007-06-04 Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
CN201610082079.6A CN105820107B (zh) 2007-06-04 2007-06-04 具有快速皮肤和生物膜穿透速度的非甾体抗炎药的前药及其新的医药用途

Publications (1)

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HK1221718A1 true HK1221718A1 (zh) 2017-06-09

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HK16109927.1A HK1221718A1 (zh) 2007-06-04 2016-08-18 具有快速皮膚和生物膜穿透速度的非甾體抗炎藥的前藥及其新的醫藥用途

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US (3) US9371284B2 (zh)
EP (2) EP2170826B1 (zh)
JP (1) JP2010529101A (zh)
KR (6) KR20210103586A (zh)
CN (2) CN101687792B (zh)
AU (4) AU2007354632B2 (zh)
BR (1) BRPI0721709B1 (zh)
CA (1) CA2691446C (zh)
DK (1) DK2170826T3 (zh)
ES (1) ES2922425T3 (zh)
HK (1) HK1221718A1 (zh)
MX (1) MX2009013136A (zh)
PL (1) PL2170826T3 (zh)
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