IT1208736B - Alogenuri dell'estere del 2-n,n,n,dimetil-alchil-amminoetanolo con acido acetico variamente sostituito e composizioni farmaceutiche che licontengono ad attivita' antiinfiammatoria e antisettica - Google Patents

Alogenuri dell'estere del 2-n,n,n,dimetil-alchil-amminoetanolo con acido acetico variamente sostituito e composizioni farmaceutiche che licontengono ad attivita' antiinfiammatoria e antisettica

Info

Publication number
IT1208736B
IT1208736B IT8647711A IT4771186A IT1208736B IT 1208736 B IT1208736 B IT 1208736B IT 8647711 A IT8647711 A IT 8647711A IT 4771186 A IT4771186 A IT 4771186A IT 1208736 B IT1208736 B IT 1208736B
Authority
IT
Italy
Prior art keywords
dimethyl
acetic acid
alchyl
aminoethanol
inflammatory
Prior art date
Application number
IT8647711A
Other languages
English (en)
Other versions
IT8647711A0 (it
Inventor
Reiner Alberto
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to IT8647711A priority Critical patent/IT1208736B/it
Publication of IT8647711A0 publication Critical patent/IT8647711A0/it
Priority to DE8787830068T priority patent/DE3765142D1/de
Priority to AT87830068T priority patent/ATE56945T1/de
Priority to EP87830068A priority patent/EP0237495B1/en
Priority to ES87830068T priority patent/ES2017529B3/es
Application granted granted Critical
Publication of IT1208736B publication Critical patent/IT1208736B/it
Priority to GR90400682T priority patent/GR3000878T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Indole Compounds (AREA)
IT8647711A 1986-03-04 1986-03-04 Alogenuri dell'estere del 2-n,n,n,dimetil-alchil-amminoetanolo con acido acetico variamente sostituito e composizioni farmaceutiche che licontengono ad attivita' antiinfiammatoria e antisettica IT1208736B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT8647711A IT1208736B (it) 1986-03-04 1986-03-04 Alogenuri dell'estere del 2-n,n,n,dimetil-alchil-amminoetanolo con acido acetico variamente sostituito e composizioni farmaceutiche che licontengono ad attivita' antiinfiammatoria e antisettica
DE8787830068T DE3765142D1 (de) 1986-03-04 1987-02-27 Halogenide des esters aus 2-n,n,n-dimethyl-alkyl-amino-aethanol mit substituierter essigsaeure, sowie diese enthaltende arzneimittel mit entzuendungshemmender und antiseptischer wirkung.
AT87830068T ATE56945T1 (de) 1986-03-04 1987-02-27 Halogenide des esters aus 2-n,n,n-dimethyl-alkyl- amino-aethanol mit substituierter essigsaeure, sowie diese enthaltende arzneimittel mit entzuendungshemmender und antiseptischer wirkung.
EP87830068A EP0237495B1 (en) 1986-03-04 1987-02-27 Halogenides of the ester of 2,n,n,n-dimethyl-alkyl-amino-ethanol with substituted acetic acid and pharmaceutical compositions having antiinflammatory and antiseptic activities containing same
ES87830068T ES2017529B3 (es) 1986-03-04 1987-02-27 Halogenuros del ester de 2 n,n,n-dimetilo-alquilamino-etanol con acido acetico sustituido y composiciones farmaceuticas que tienen actividades antiinflamatorias y antisepticas que contienen dichos compuestos.
GR90400682T GR3000878T3 (en) 1986-03-04 1990-09-27 Halogenides of the ester of 2,n,n,n-dimethyl-alkyl-amino-ethanol with substituted acetic acid and pharmaceutical compositions having antiinflammatory and antiseptic activities containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8647711A IT1208736B (it) 1986-03-04 1986-03-04 Alogenuri dell'estere del 2-n,n,n,dimetil-alchil-amminoetanolo con acido acetico variamente sostituito e composizioni farmaceutiche che licontengono ad attivita' antiinfiammatoria e antisettica

Publications (2)

Publication Number Publication Date
IT8647711A0 IT8647711A0 (it) 1986-03-04
IT1208736B true IT1208736B (it) 1989-07-10

Family

ID=11262040

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8647711A IT1208736B (it) 1986-03-04 1986-03-04 Alogenuri dell'estere del 2-n,n,n,dimetil-alchil-amminoetanolo con acido acetico variamente sostituito e composizioni farmaceutiche che licontengono ad attivita' antiinfiammatoria e antisettica

Country Status (6)

Country Link
EP (1) EP0237495B1 (it)
AT (1) ATE56945T1 (it)
DE (1) DE3765142D1 (it)
ES (1) ES2017529B3 (it)
GR (1) GR3000878T3 (it)
IT (1) IT1208736B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA882957B (en) * 1987-04-27 1989-12-27 Syntex Pharma Int Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal anti-inflammatory drugs
US5196568A (en) * 1988-04-07 1993-03-23 Sepracor, Inc. Compounds useful in enzymatic resolution systems and their preparation
IL89848A (en) * 1988-04-07 1997-08-14 Sepracor Chiral ester derivatives
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
CA2657636C (en) * 2006-07-18 2021-11-09 Techfields Biochem Co. Ltd Positively charged water soluble prodrugs of ibuprofen with very fast skin penetration rate
CN103772259B (zh) * 2006-08-08 2016-08-31 于崇曦 具有快速皮肤穿透速度的带正电荷的芳基和杂芳基乙酸类前药
CN103772258B (zh) * 2006-08-08 2016-09-28 于崇曦 具有快速皮肤穿透速度的带正电荷的芳基和杂芳基乙酸类前药
KR20150058566A (ko) 2007-06-04 2015-05-28 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 ｎｓａｉａ 약물전구체 및 이들의 새로운 의약적 용도
KR20210123406A (ko) 2008-12-04 2021-10-13 충시 위 고투과력을 가진 조성물 및 이의 적용

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150137A (en) * 1975-12-24 1979-04-17 Hisamitsu Pharmaceutical Co. Inc. Pyridylalkyl esters of 2-(p-isobutylphenyl)acetic acid and propionic acids and use
DE3023206A1 (de) * 1979-11-02 1982-01-14 Efeka Friedrich & Kaufmann GmbH & Co KG, 3000 Hannover Indometacin-ester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
ES2017529B3 (es) 1991-02-16
EP0237495A3 (en) 1988-06-22
ATE56945T1 (de) 1990-10-15
EP0237495B1 (en) 1990-09-26
DE3765142D1 (de) 1990-10-31
IT8647711A0 (it) 1986-03-04
EP0237495A2 (en) 1987-09-16
GR3000878T3 (en) 1991-11-15

Similar Documents

Publication Publication Date Title
DE19575041I2 (de) Substituierte Acyl-Derivate von 1, 2, 3, 4-Tetrahydro-6, 7-dimethoxy-3-isoquinolin-Carbonsaeure
FI892787A0 (fi) Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-indolyylialkyyli-4-(substituoitu pyridinyyli)piperatsiinien valmistamiseksi
IT1208736B (it) Alogenuri dell'estere del 2-n,n,n,dimetil-alchil-amminoetanolo con acido acetico variamente sostituito e composizioni farmaceutiche che licontengono ad attivita' antiinfiammatoria e antisettica
DE3863857D1 (de) Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung.
FI862757A (fi) Pyridonkarbonsyraderivat och foerfarande foer framstaellning av dessa.
ES2172580T3 (es) 1,3-oxatiolanos sustituidos con propiedades antiviricas.
AU5706986A (en) N-acyl-alpha-amino-alpha-hydroxy acetic acid ester
FI792281A (fi) Nya kemiska foereningar
FR2355822A1 (fr) Derives d'esters de l'acide indolacetique. utiles comme anti-inflammatoires et analgesiques
ES2051674T3 (es) Derivados de benzoxazinona y benzotiazinona dotados de actividad cardiovascular.
DE68905406D1 (de) Chinolin-verbindung.
MY104238A (en) Prodrugs of antiinflammatory 3-acyl-2-oxindole-1 -carboxamides.
IE882107L (en) Pyrimidones
IT1205640B (it) Nuovi composti ad attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1238679B (it) Derivato otticamente attivo dell'acido d-2-(6-metossi-2-naftil)- propionico e composizioni farmaceutiche che lo contengono
DE69415050D1 (de) Hexahydronaphthalenesterderivate, ihre Herstellung und ihre therapeutischen Anwendungen
ES531480A0 (es) Derivados del acido d-2-(6-metoxi-2-naftil)-propionico
ES2062340T3 (es) Derivados de 2-carbapenemo antibacterianos.
IT1190662B (it) Composto ad attivita' analgesica,antiinfiammatoria e mucoregolatrice procedimento per la sua prepatazione e relative composizioni farmaceutiche
DE68903188D1 (de) Acylsulfonamid-derivate von alpha-carbocyclyltoluylsaeuren und ihre verwendung als leukotrienantagonisten.
EP0284069A3 (en) Benzopyranopyridineacetic acid ester compounds and their pharmaceutical uses
IT1194209B (it) Composti fluorurati ad attivita' analgesica e antiinfiammatoria

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940208