ES2017529B3 - Halogenuros del ester de 2 n,n,n-dimetilo-alquilamino-etanol con acido acetico sustituido y composiciones farmaceuticas que tienen actividades antiinflamatorias y antisepticas que contienen dichos compuestos. - Google Patents

Halogenuros del ester de 2 n,n,n-dimetilo-alquilamino-etanol con acido acetico sustituido y composiciones farmaceuticas que tienen actividades antiinflamatorias y antisepticas que contienen dichos compuestos.

Info

Publication number
ES2017529B3
ES2017529B3 ES87830068T ES87830068T ES2017529B3 ES 2017529 B3 ES2017529 B3 ES 2017529B3 ES 87830068 T ES87830068 T ES 87830068T ES 87830068 T ES87830068 T ES 87830068T ES 2017529 B3 ES2017529 B3 ES 2017529B3
Authority
ES
Spain
Prior art keywords
dimethyl
acetic acid
alkylamino
pharmaceutical
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87830068T
Other languages
English (en)
Inventor
Alberto Reiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Application granted granted Critical
Publication of ES2017529B3 publication Critical patent/ES2017529B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ES87830068T 1986-03-04 1987-02-27 Halogenuros del ester de 2 n,n,n-dimetilo-alquilamino-etanol con acido acetico sustituido y composiciones farmaceuticas que tienen actividades antiinflamatorias y antisepticas que contienen dichos compuestos. Expired - Lifetime ES2017529B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8647711A IT1208736B (it) 1986-03-04 1986-03-04 Alogenuri dell'estere del 2-n,n,n,dimetil-alchil-amminoetanolo con acido acetico variamente sostituito e composizioni farmaceutiche che licontengono ad attivita' antiinfiammatoria e antisettica

Publications (1)

Publication Number Publication Date
ES2017529B3 true ES2017529B3 (es) 1991-02-16

Family

ID=11262040

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87830068T Expired - Lifetime ES2017529B3 (es) 1986-03-04 1987-02-27 Halogenuros del ester de 2 n,n,n-dimetilo-alquilamino-etanol con acido acetico sustituido y composiciones farmaceuticas que tienen actividades antiinflamatorias y antisepticas que contienen dichos compuestos.

Country Status (6)

Country Link
EP (1) EP0237495B1 (es)
AT (1) ATE56945T1 (es)
DE (1) DE3765142D1 (es)
ES (1) ES2017529B3 (es)
GR (1) GR3000878T3 (es)
IT (1) IT1208736B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6452742A (en) * 1987-04-27 1989-02-28 Syntex Pharma Int Omega-quaternary ammonium alkyl ester and thioester of acidic non-steroidal antiinflammatory
US5196568A (en) * 1988-04-07 1993-03-23 Sepracor, Inc. Compounds useful in enzymatic resolution systems and their preparation
IL89848A (en) * 1988-04-07 1997-08-14 Sepracor Chiral ester derivatives
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
WO2008010025A1 (en) * 2006-07-18 2008-01-24 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of ibuprofen with very fast skin penetration rate
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
CN103772259B (zh) * 2006-08-08 2016-08-31 于崇曦 具有快速皮肤穿透速度的带正电荷的芳基和杂芳基乙酸类前药
CN103772258B (zh) * 2006-08-08 2016-09-28 于崇曦 具有快速皮肤穿透速度的带正电荷的芳基和杂芳基乙酸类前药
BRPI0721709B1 (pt) 2007-06-04 2024-03-12 Techfields Inc. PRÓ-FÁRMACOS DE NSAIAs, PROCESSO PARA PREPARAÇÃO DOS MESMOS, SEU USO, SISTEMAS TERAPÊUTICOS DE APLICAÇÃO TRANSDÉRMICA E COMPOSIÇÃO QUE OS COMPREENDE
TWI383802B (zh) 2008-12-04 2013-02-01 Chongxi Yu 高滲透性組合物及其應用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150137A (en) * 1975-12-24 1979-04-17 Hisamitsu Pharmaceutical Co. Inc. Pyridylalkyl esters of 2-(p-isobutylphenyl)acetic acid and propionic acids and use
DE3023206A1 (de) * 1979-11-02 1982-01-14 Efeka Friedrich & Kaufmann GmbH & Co KG, 3000 Hannover Indometacin-ester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
EP0237495A3 (en) 1988-06-22
IT1208736B (it) 1989-07-10
EP0237495B1 (en) 1990-09-26
ATE56945T1 (de) 1990-10-15
GR3000878T3 (en) 1991-11-15
EP0237495A2 (en) 1987-09-16
DE3765142D1 (de) 1990-10-31
IT8647711A0 (it) 1986-03-04

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