DE69226798D1 - Sialsäurederivate - Google Patents

Sialsäurederivate

Info

Publication number
DE69226798D1
DE69226798D1 DE69226798T DE69226798T DE69226798D1 DE 69226798 D1 DE69226798 D1 DE 69226798D1 DE 69226798 T DE69226798 T DE 69226798T DE 69226798 T DE69226798 T DE 69226798T DE 69226798 D1 DE69226798 D1 DE 69226798D1
Authority
DE
Germany
Prior art keywords
acid derivatives
sialic acid
anomer
acetyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69226798T
Other languages
English (en)
Other versions
DE69226798T2 (de
Inventor
Kaoru Okamoto
Shinji Morita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Zoki Pharmaceutical Co Ltd
Original Assignee
Nippon Zoki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Zoki Pharmaceutical Co Ltd filed Critical Nippon Zoki Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69226798D1 publication Critical patent/DE69226798D1/de
Publication of DE69226798T2 publication Critical patent/DE69226798T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE69226798T 1991-03-06 1992-03-06 Sialsäurederivate Expired - Fee Related DE69226798T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6801791 1991-03-06

Publications (2)

Publication Number Publication Date
DE69226798D1 true DE69226798D1 (de) 1998-10-08
DE69226798T2 DE69226798T2 (de) 1999-04-15

Family

ID=13361639

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69226798T Expired - Fee Related DE69226798T2 (de) 1991-03-06 1992-03-06 Sialsäurederivate

Country Status (4)

Country Link
US (1) US5438125A (de)
EP (1) EP0502827B1 (de)
AT (1) ATE170528T1 (de)
DE (1) DE69226798T2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5489675A (en) * 1992-06-25 1996-02-06 E. I. Du Pont De Nemours And Company Disaccharide sialidase substrates and inhibitors
US5783564A (en) * 1993-12-24 1998-07-21 Mitsubishi Chemical Corporation Sialic acid derivatives
TW479061B (en) * 1993-12-24 2002-03-11 Mitsubishi Chem Corp Sialic acid derivatives
US6066323A (en) * 1994-02-02 2000-05-23 The United States Of America As Represented By The Secretary Of The Army Use of antibodies to sialidase as anti-infectious agents and anti-inflammatory agents
KR19980703698A (ko) * 1996-02-08 1998-12-05 모리따 겐조 암 전이 억제 항암제 물질
JP4005115B1 (ja) * 2007-02-08 2007-11-07 日本臓器製薬株式会社 疼痛疾患治療剤
US9119866B2 (en) 2008-04-08 2015-09-01 Huiru Wang Glycan-based drugs, therapies and biomarkers
WO2010131712A1 (ja) * 2009-05-15 2010-11-18 財団法人ヒューマンサイエンス振興財団 Ｇｎｅタンパク質の機能低下に起因する疾患の治療用医薬剤、食品組成物、食品添加物
CN112175103B (zh) * 2020-10-29 2022-07-15 绍兴文理学院 一种含有聚唾液酸基团的聚甘油脂肪酸酯衍生物及其合成方法和其在药物制剂中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3219209A1 (de) * 1981-05-22 1982-12-09 Kanto Ishi Pharmaceutical Co., Ltd., Tokyo N-acetylneuraminsaeure-derivate
JPS60190791A (ja) * 1984-03-09 1985-09-28 Kanto Ishi Pharma Co Ltd シアル酸誘導体およびその製造法
JPS62221694A (ja) * 1986-03-20 1987-09-29 Kazuo Achinami シアロ−ホスホリル−グルコサミン誘導体及びその製造方法
HU198216B (en) * 1986-05-12 1989-08-28 Kanto Ishi Pharma Co Ltd Process for producing sialosyl-cholesterin and pharmaceutical compositions containing them as active components
JPH07100709B2 (ja) * 1986-06-11 1995-11-01 日本臓器製薬株式会社 新規グリコシル化法
US5037969A (en) * 1986-07-03 1991-08-06 Takeda Chemical Industries, Ltd. Glycosyl derivatives and use thereof
US4990603A (en) * 1986-07-04 1991-02-05 Mect Corporation Sialic acid derivatives and process therefor
JPS6344590A (ja) * 1986-08-12 1988-02-25 Mect Corp シアル酸誘導体の製造方法
US5034516A (en) * 1987-08-04 1991-07-23 University Of Ottawa Synthetic antigens of sialic acid and derivatives thereof
JPS6461493A (en) * 1987-08-28 1989-03-08 Kanto Ishi Pharma Co Ltd Production of sialosylceramides
JPH01125394A (ja) * 1987-11-10 1989-05-17 Mect Corp シアロシルグリセロリピッド類及びその製造方法
JPH01228997A (ja) * 1988-03-10 1989-09-12 Mect Corp シアロシルグリセライド類及びその製造方法
JPH02145596A (ja) * 1988-11-29 1990-06-05 Mect Corp 活性エステル基を持つシタル酸誘導体
JPH02202895A (ja) * 1989-02-01 1990-08-10 Mect Corp 非天然型シアロシルセラミド類及びその製造方法
JPH02209885A (ja) * 1989-02-08 1990-08-21 Mect Corp アミド結合したシアロシルグリセロリピッド

Also Published As

Publication number Publication date
EP0502827A1 (de) 1992-09-09
EP0502827B1 (de) 1998-09-02
DE69226798T2 (de) 1999-04-15
US5438125A (en) 1995-08-01
ATE170528T1 (de) 1998-09-15

Similar Documents

Publication Publication Date Title
HK1011967A1 (en) Amide derivatives having anti-hyper cholesteremic activity their preparation and their therapeutic uses
ATE157346T1 (de) Hexahydronapththalinesterderivate, ihre herstellung und ihre therapeutischen verwendungen
MX9302300A (es) Derivados esteroides para el tratamiento de hipertrofia prostatica, su preparacion y sus usos.
NO934536D0 (no) Fenoksy- og fenoksyalkyl-pepiridiner som antivirale midler
NZ214156A (en) Quindone derivatives and pharmaceutical compositions
DE69226798D1 (de) Sialsäurederivate
IE890177L (en) Piperidinyl derivatives
HUT54362A (en) Process for producing cumarin derivatives and pharmaceutical compositions containing them
DK0570850T3 (da) Benzo(b)thiophen-3-yl-piperaziner, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
ATE174324T1 (de) Hexahydronaphthalenesterderivate, ihre herstellung und ihre therapeutischen anwendungen
GR3006108T3 (de)
FI883507A0 (fi) Naftotiazepinderivat och deras framstaellning.
ATE160567T1 (de) Psoralen-derivate, deren herstellung und verwendung als arzneimittel

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee