ATE170528T1 - Sialsäurederivate - Google Patents

Sialsäurederivate

Info

Publication number
ATE170528T1
ATE170528T1 AT92810176T AT92810176T ATE170528T1 AT E170528 T1 ATE170528 T1 AT E170528T1 AT 92810176 T AT92810176 T AT 92810176T AT 92810176 T AT92810176 T AT 92810176T AT E170528 T1 ATE170528 T1 AT E170528T1
Authority
AT
Austria
Prior art keywords
acid derivatives
sialic acid
anomer
acetyl
hydrogen
Prior art date
Application number
AT92810176T
Other languages
English (en)
Inventor
Kaoru Okamoto
Shinji Morita
Original Assignee
Nippon Zoki Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Zoki Pharmaceutical Co filed Critical Nippon Zoki Pharmaceutical Co
Application granted granted Critical
Publication of ATE170528T1 publication Critical patent/ATE170528T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AT92810176T 1991-03-06 1992-03-06 Sialsäurederivate ATE170528T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6801791 1991-03-06

Publications (1)

Publication Number Publication Date
ATE170528T1 true ATE170528T1 (de) 1998-09-15

Family

ID=13361639

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92810176T ATE170528T1 (de) 1991-03-06 1992-03-06 Sialsäurederivate

Country Status (4)

Country Link
US (1) US5438125A (de)
EP (1) EP0502827B1 (de)
AT (1) ATE170528T1 (de)
DE (1) DE69226798T2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5489675A (en) * 1992-06-25 1996-02-06 E. I. Du Pont De Nemours And Company Disaccharide sialidase substrates and inhibitors
US5783564A (en) * 1993-12-24 1998-07-21 Mitsubishi Chemical Corporation Sialic acid derivatives
TW479061B (en) * 1993-12-24 2002-03-11 Mitsubishi Chem Corp Sialic acid derivatives
US6066323A (en) * 1994-02-02 2000-05-23 The United States Of America As Represented By The Secretary Of The Army Use of antibodies to sialidase as anti-infectious agents and anti-inflammatory agents
KR19980703698A (ko) * 1996-02-08 1998-12-05 모리따 겐조 암 전이 억제 항암제 물질
JP4005115B1 (ja) * 2007-02-08 2007-11-07 日本臓器製薬株式会社 疼痛疾患治療剤
US9119866B2 (en) 2008-04-08 2015-09-01 Huiru Wang Glycan-based drugs, therapies and biomarkers
CN102427817B (zh) * 2009-05-15 2015-02-11 财团法人日本健康科学振兴财团 起因于gne蛋白质功能降低的疾病的治疗用药物、食品组合物、食品添加剂
CN112175103B (zh) * 2020-10-29 2022-07-15 绍兴文理学院 一种含有聚唾液酸基团的聚甘油脂肪酸酯衍生物及其合成方法和其在药物制剂中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3249916C2 (de) * 1981-05-22 1992-04-02 Mect Corp., Tokio/Tokyo, Jp
JPS60190791A (ja) * 1984-03-09 1985-09-28 Kanto Ishi Pharma Co Ltd シアル酸誘導体およびその製造法
JPS62221694A (ja) * 1986-03-20 1987-09-29 Kazuo Achinami シアロ−ホスホリル−グルコサミン誘導体及びその製造方法
HU198216B (en) * 1986-05-12 1989-08-28 Kanto Ishi Pharma Co Ltd Process for producing sialosyl-cholesterin and pharmaceutical compositions containing them as active components
JPH07100709B2 (ja) * 1986-06-11 1995-11-01 日本臓器製薬株式会社 新規グリコシル化法
US5037969A (en) * 1986-07-03 1991-08-06 Takeda Chemical Industries, Ltd. Glycosyl derivatives and use thereof
US4990603A (en) * 1986-07-04 1991-02-05 Mect Corporation Sialic acid derivatives and process therefor
JPS6344590A (ja) * 1986-08-12 1988-02-25 Mect Corp シアル酸誘導体の製造方法
US5034516A (en) * 1987-08-04 1991-07-23 University Of Ottawa Synthetic antigens of sialic acid and derivatives thereof
JPS6461493A (en) * 1987-08-28 1989-03-08 Kanto Ishi Pharma Co Ltd Production of sialosylceramides
JPH01125394A (ja) * 1987-11-10 1989-05-17 Mect Corp シアロシルグリセロリピッド類及びその製造方法
JPH01228997A (ja) * 1988-03-10 1989-09-12 Mect Corp シアロシルグリセライド類及びその製造方法
JPH02145596A (ja) * 1988-11-29 1990-06-05 Mect Corp 活性エステル基を持つシタル酸誘導体
JPH02202895A (ja) * 1989-02-01 1990-08-10 Mect Corp 非天然型シアロシルセラミド類及びその製造方法
JPH02209885A (ja) * 1989-02-08 1990-08-21 Mect Corp アミド結合したシアロシルグリセロリピッド

Also Published As

Publication number Publication date
EP0502827A1 (de) 1992-09-09
EP0502827B1 (de) 1998-09-02
US5438125A (en) 1995-08-01
DE69226798D1 (de) 1998-10-08
DE69226798T2 (de) 1999-04-15

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties