DE3863857D1 - Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung. - Google Patents
Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung.Info
- Publication number
- DE3863857D1 DE3863857D1 DE8888305654T DE3863857T DE3863857D1 DE 3863857 D1 DE3863857 D1 DE 3863857D1 DE 8888305654 T DE8888305654 T DE 8888305654T DE 3863857 T DE3863857 T DE 3863857T DE 3863857 D1 DE3863857 D1 DE 3863857D1
- Authority
- DE
- Germany
- Prior art keywords
- chem
- arylthioalkylphenylcarbonic
- acids
- compositions
- arylthioalkylphenylcarboxylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/067,199 US4752616A (en) | 1987-06-29 | 1987-06-29 | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3863857D1 true DE3863857D1 (de) | 1991-08-29 |
Family
ID=22074375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888305654T Expired - Fee Related DE3863857D1 (de) | 1987-06-29 | 1988-06-20 | Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4752616A (de) |
EP (1) | EP0297768B1 (de) |
JP (1) | JPS6426548A (de) |
AT (1) | ATE65500T1 (de) |
DE (1) | DE3863857D1 (de) |
ES (1) | ES2029885T3 (de) |
GR (1) | GR3003015T3 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3724923A1 (de) * | 1987-07-28 | 1989-02-09 | Boehringer Mannheim Gmbh | Neue schwefelverbindungen, verfahren zu ihrer herstellung sowie arzneimittel |
US4931460A (en) * | 1987-09-17 | 1990-06-05 | E. R. Squibb & Sons, Inc. | Post-ischemic myocardial dysfunction using thromboxane A2 antagonists |
US4925873A (en) * | 1988-09-01 | 1990-05-15 | E. R. Squibb & Sons, Inc. | Method of treating skin injuries using thromboxane A2 receptor antagonists |
US4959383A (en) * | 1988-10-31 | 1990-09-25 | E. R. Squibb & Sons, Inc. | Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use |
US5070099A (en) * | 1988-10-31 | 1991-12-03 | E. R. Squibb & Sons, Inc. | Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use |
US5106991A (en) * | 1989-06-02 | 1992-04-21 | E. R. Squibb & Sons, Inc. | Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof |
US4975452A (en) * | 1989-06-02 | 1990-12-04 | E. R. Squibb & Sons, Inc. | Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof |
US5177069A (en) * | 1989-12-13 | 1993-01-05 | Kissei Pharmaceutical Co., Ltd. | Naphthysulfonylalkanoic acid compounds and pharmaceutical compositions thereof |
JPH06506469A (ja) * | 1991-04-05 | 1994-07-21 | スミスクライン・ビーチャム・コーポレイション | 二置換ナフタレン |
US5280034A (en) * | 1991-08-23 | 1994-01-18 | E. R. Squibb & Sons, Inc. | Bis-heterocyclic prostaglandin analogs |
US5827868A (en) * | 1991-10-07 | 1998-10-27 | E. R. Squibb & Sons, Inc. | Prostaglandin analogs |
US6670398B2 (en) * | 1997-05-14 | 2003-12-30 | Atherogenics, Inc. | Compounds and methods for treating transplant rejection |
DK0981343T3 (da) * | 1997-05-14 | 2006-01-30 | Atherogenics Inc | Probucolmonoestere til behandling af kardiovaskulær og inflammatorisk sygdom |
US6852878B2 (en) * | 1998-05-14 | 2005-02-08 | Atherogenics, Inc. | Thioketals and thioethers for inhibiting the expression of VCAM-1 |
EP1019034A2 (de) * | 1997-07-01 | 2000-07-19 | Atherogenics, Inc. | Verbesserung antioxidativer therapie für hyperproliferative zustanden |
JP4334233B2 (ja) * | 2001-04-11 | 2009-09-30 | アセロジエニクス・インコーポレイテツド | プロブコールモノエステルによって血漿hdlコレステロールレベルを上昇させ、hdlの機能性を改善するための方法 |
EP2147679B1 (de) | 2001-07-25 | 2014-06-25 | Raptor Pharmaceutical, Inc. | Zusammensetzungen für den Blut-Hirn-Schrankentransport |
US20040110803A1 (en) * | 2002-09-13 | 2004-06-10 | Hossein Dovlatabadi | Methods and compositions for the use of D-malic acid to decrease serum triglyceride, cholesterol and lipoprotein levels |
BRPI0406738A (pt) * | 2003-01-13 | 2005-12-20 | Atherogenics Inc | Processo de preparação de ésteres e éteres de probucol e derivados desse |
WO2005102323A2 (en) | 2004-04-20 | 2005-11-03 | Atherogenics, Inc. | Process of preparing esters and ethers of probucol and derivatives thereof |
US7271274B2 (en) | 2004-04-20 | 2007-09-18 | Ahterogenics, Inc. | Phenolic antioxidants for the treatment of disorders including arthritis, asthma and coronary artery disease |
DK1889198T3 (da) | 2005-04-28 | 2015-02-09 | Proteus Digital Health Inc | Farma-informatiksystem |
WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
US8252840B2 (en) * | 2007-03-26 | 2012-08-28 | Salutria Pharmaceuticals Llc | Methods of derivatives of probucol for the treatment of type II diabetes |
US20080280985A1 (en) * | 2007-03-27 | 2008-11-13 | Scott Robert A D | Methods and Compositions Using Certain Phenolic Derivatives for the Treatment of Diabetes |
DK2398500T3 (da) | 2009-02-20 | 2019-05-13 | 2 Bbb Medicines B V | Glutathion-baseret lægemiddelafgivelsessystem |
IL255113B (en) | 2009-05-06 | 2022-09-01 | Laboratory Skin Care Inc | Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
EP3142655B1 (de) | 2014-05-16 | 2020-12-02 | Cumberland Pharmaceuticals Inc. | Zusammensetzungen und verfahren zur behandlung von herzfibrose mit ifetroban |
WO2017004040A1 (en) | 2015-06-30 | 2017-01-05 | Cumberland Pharmaceuticals, Inc. | Thromboxane receptor antagonists in aerd/asthma |
US10064845B2 (en) | 2016-05-11 | 2018-09-04 | Cumberland Pharmaceuticals, Inc. | Compositions and methods of treating muscular dystrophy with thromboxane-A2 receptor antagonists |
CN113754570A (zh) * | 2020-06-02 | 2021-12-07 | 石家庄圣泰化工有限公司 | 一种2-丙腈磺酰基乙腈的合成方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
US3600437A (en) * | 1969-05-28 | 1971-08-17 | Lilly Co Eli | Substituted phenylalkanoic acids and derivatives thereof |
US3880916A (en) * | 1969-09-17 | 1975-04-29 | Ciba Geigy Corp | Cycloaliphatic acids |
US3825587A (en) * | 1970-05-05 | 1974-07-23 | Rorer Inc William H | Substituted phenylacetic acid compounds |
SE377113B (de) * | 1971-05-15 | 1975-06-23 | Ciba Geigy Ag | |
US3845089A (en) * | 1972-07-27 | 1974-10-29 | Zoecon Corp | Phenylheptadienoates |
US4074057A (en) * | 1973-12-12 | 1978-02-14 | Takeda Chemical Co., Ltd. | 2-Halopropionic acid and its derivatives |
DE2809377A1 (de) * | 1978-03-04 | 1979-09-13 | Boehringer Mannheim Gmbh | Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
DE3000377A1 (de) * | 1980-01-07 | 1981-07-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
DE3169761D1 (en) * | 1981-01-09 | 1985-05-09 | Fisons Plc | Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them |
US4780558A (en) * | 1985-02-15 | 1988-10-25 | Ciba-Geigy Corporation | Sulfone compounds |
-
1987
- 1987-06-29 US US07/067,199 patent/US4752616A/en not_active Expired - Lifetime
-
1988
- 1988-06-20 ES ES198888305654T patent/ES2029885T3/es not_active Expired - Lifetime
- 1988-06-20 EP EP88305654A patent/EP0297768B1/de not_active Expired - Lifetime
- 1988-06-20 DE DE8888305654T patent/DE3863857D1/de not_active Expired - Fee Related
- 1988-06-20 AT AT88305654T patent/ATE65500T1/de not_active IP Right Cessation
- 1988-06-28 JP JP63162371A patent/JPS6426548A/ja active Pending
-
1991
- 1991-10-24 GR GR91401623T patent/GR3003015T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE65500T1 (de) | 1991-08-15 |
ES2029885T3 (es) | 1992-10-01 |
EP0297768A1 (de) | 1989-01-04 |
EP0297768B1 (de) | 1991-07-24 |
GR3003015T3 (en) | 1993-02-17 |
US4752616A (en) | 1988-06-21 |
JPS6426548A (en) | 1989-01-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |