HK1215969A1 - 用於检测抗生物制品治疗的中和性自身抗体的测定 - Google Patents

用於检测抗生物制品治疗的中和性自身抗体的测定 Download PDF

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Publication number
HK1215969A1
HK1215969A1 HK16103834.6A HK16103834A HK1215969A1 HK 1215969 A1 HK1215969 A1 HK 1215969A1 HK 16103834 A HK16103834 A HK 16103834A HK 1215969 A1 HK1215969 A1 HK 1215969A1
Authority
HK
Hong Kong
Prior art keywords
neutralizing
therapy
present
biologic
assays
Prior art date
Application number
HK16103834.6A
Other languages
English (en)
Chinese (zh)
Inventor
Scott Hauenstein
Sharat Singh
Original Assignee
Nestec S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/802,117 external-priority patent/US20130266963A1/en
Application filed by Nestec S.A. filed Critical Nestec S.A.
Publication of HK1215969A1 publication Critical patent/HK1215969A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/525—Tumor necrosis factor [TNF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK16103834.6A 2012-11-30 2013-11-27 用於检测抗生物制品治疗的中和性自身抗体的测定 HK1215969A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261732251P 2012-11-30 2012-11-30
US61/732,251 2012-11-30
US13/802,117 US20130266963A1 (en) 2011-07-06 2013-03-13 Assay for detecting neutralizing autoantibodies to biologic therapy
US13/802,117 2013-03-13
PCT/IB2013/060458 WO2014083520A2 (en) 2012-11-30 2013-11-27 Assays for detecting neutralizing autoantibodies to biologic therapy

Publications (1)

Publication Number Publication Date
HK1215969A1 true HK1215969A1 (zh) 2016-09-30

Family

ID=50828561

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16103834.6A HK1215969A1 (zh) 2012-11-30 2013-11-27 用於检测抗生物制品治疗的中和性自身抗体的测定

Country Status (13)

Country Link
EP (1) EP2926136A2 (enExample)
JP (1) JP2016502091A (enExample)
KR (1) KR20150088890A (enExample)
CN (1) CN105074461A (enExample)
AU (1) AU2013350817A1 (enExample)
BR (1) BR112015012482A2 (enExample)
CA (1) CA2892766A1 (enExample)
HK (1) HK1215969A1 (enExample)
IL (1) IL238995A0 (enExample)
MX (1) MX2015006852A (enExample)
RU (1) RU2015125739A (enExample)
SG (2) SG11201504097PA (enExample)
WO (1) WO2014083520A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012004877A (es) 2009-10-26 2012-05-23 Prometheus Lab Inc Analisis para la deteccion de farmacos anti-tnf y autoanticuerpos.
SG189391A1 (en) 2010-10-18 2013-05-31 Nestec Sa Methods for determining anti-drug antibody isotypes
AU2012278802B2 (en) 2011-07-06 2015-11-26 Société des Produits Nestlé S.A. Assays for detecting neutralizing autoantibodies to biologic therapy with TNF alpha
JP2018500553A (ja) 2014-12-05 2018-01-11 ネステク ソシエテ アノニム 患者試料における生物製剤の検出のための間接的均一移動度シフトアッセイ
CN107110853A (zh) 2015-01-09 2017-08-29 阿通诺米斯公司 确定TNFα抑制药及其相应抗药抗体的量的通用测定法
US11119096B2 (en) 2016-07-08 2021-09-14 W. Health L.P. Universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples
CN110546506B (zh) * 2017-03-31 2023-04-04 埃博灵克斯股份有限公司 改进的免疫原性测定法
CN114902052B (zh) * 2020-01-02 2025-07-18 豪夫迈·罗氏有限公司 Ada应答特异性化测定
CN111024958B (zh) * 2020-03-11 2020-06-23 同昕生物技术（北京）有限公司 用于检测单抗药物和抗单抗药物抗体的试剂及其应用
CN112730846B (zh) * 2020-12-18 2023-12-15 安渡生物医药(杭州)有限公司 一种用于小鼠血样检测免疫复合物的方法
CN114047343B (zh) * 2022-01-13 2022-05-31 美迪西普亚医药科技(上海)有限公司 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用
CN117871856A (zh) * 2023-12-15 2024-04-12 首都医科大学附属北京地坛医院 可溶性因子在无症状神经梅毒检测中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012004877A (es) * 2009-10-26 2012-05-23 Prometheus Lab Inc Analisis para la deteccion de farmacos anti-tnf y autoanticuerpos.
JP2013527444A (ja) * 2010-04-29 2013-06-27 テラディアグ・ソシエテ・アノニム 抗体を検出するための方法
SG189391A1 (en) * 2010-10-18 2013-05-31 Nestec Sa Methods for determining anti-drug antibody isotypes
WO2012154253A1 (en) * 2011-02-17 2012-11-15 Prometheus Laboratories Inc. ASSAYS FOR DETECTING AUTOANTIBODIES TO ANTI-TNFα DRUGS
AU2012278802B2 (en) * 2011-07-06 2015-11-26 Société des Produits Nestlé S.A. Assays for detecting neutralizing autoantibodies to biologic therapy with TNF alpha

Also Published As

Publication number Publication date
CN105074461A (zh) 2015-11-18
CA2892766A1 (en) 2014-06-05
WO2014083520A3 (en) 2014-07-31
EP2926136A2 (en) 2015-10-07
MX2015006852A (es) 2015-09-16
SG11201504097PA (en) 2015-06-29
BR112015012482A2 (pt) 2017-07-11
KR20150088890A (ko) 2015-08-03
WO2014083520A2 (en) 2014-06-05
IL238995A0 (en) 2015-07-30
SG10201703210XA (en) 2017-06-29
RU2015125739A (ru) 2017-01-13
JP2016502091A (ja) 2016-01-21
AU2013350817A1 (en) 2015-06-11

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