CN105074461A - 用于检测抗生物制品治疗的中和性自身抗体的测定 - Google Patents
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- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G—PHYSICS
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- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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| US13/802,117 | 2013-03-13 | ||
| PCT/IB2013/060458 WO2014083520A2 (en) | 2012-11-30 | 2013-11-27 | Assays for detecting neutralizing autoantibodies to biologic therapy |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109791142A (zh) * | 2016-07-08 | 2019-05-21 | W 健康公司 | 用于确定样品中治疗性单克隆抗体及其相应抗药物抗体的量的通用测定 |
| CN110546506A (zh) * | 2017-03-31 | 2019-12-06 | 埃博灵克斯股份有限公司 | 改进的免疫原性测定法 |
| CN111024958A (zh) * | 2020-03-11 | 2020-04-17 | 同昕生物技术（北京）有限公司 | 用于检测单抗药物和抗单抗药物抗体的试剂及其应用 |
| CN114902052A (zh) * | 2020-01-02 | 2022-08-12 | 豪夫迈·罗氏有限公司 | Ada应答特异性化测定 |
| CN117871856A (zh) * | 2023-12-15 | 2024-04-12 | 首都医科大学附属北京地坛医院 | 可溶性因子在无症状神经梅毒检测中的应用 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2012004877A (es) | 2009-10-26 | 2012-05-23 | Prometheus Lab Inc | Analisis para la deteccion de farmacos anti-tnf y autoanticuerpos. |
| SG189391A1 (en) | 2010-10-18 | 2013-05-31 | Nestec Sa | Methods for determining anti-drug antibody isotypes |
| AU2012278802B2 (en) | 2011-07-06 | 2015-11-26 | Société des Produits Nestlé S.A. | Assays for detecting neutralizing autoantibodies to biologic therapy with TNF alpha |
| JP2018500553A (ja) | 2014-12-05 | 2018-01-11 | ネステク ソシエテ アノニム | 患者試料における生物製剤の検出のための間接的均一移動度シフトアッセイ |
| CN107110853A (zh) | 2015-01-09 | 2017-08-29 | 阿通诺米斯公司 | 确定TNFα抑制药及其相应抗药抗体的量的通用测定法 |
| CN112730846B (zh) * | 2020-12-18 | 2023-12-15 | 安渡生物医药(杭州)有限公司 | 一种用于小鼠血样检测免疫复合物的方法 |
| CN114047343B (zh) * | 2022-01-13 | 2022-05-31 | 美迪西普亚医药科技(上海)有限公司 | 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011056590A1 (en) * | 2009-10-26 | 2011-05-12 | Prometheus Laboratories Inc. | Assays for the detection of anti-tnf drugs and autoantibodies |
| WO2011135024A1 (en) * | 2010-04-29 | 2011-11-03 | Biomedical Diagnostics Sa | Methods for detecting antibodies |
| CN103782172A (zh) * | 2011-07-06 | 2014-05-07 | 雀巢产品技术援助有限公司 | 检测针对使用TNFα的生物疗法的中和性自体抗体的测定法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG189391A1 (en) * | 2010-10-18 | 2013-05-31 | Nestec Sa | Methods for determining anti-drug antibody isotypes |
| WO2012154253A1 (en) * | 2011-02-17 | 2012-11-15 | Prometheus Laboratories Inc. | ASSAYS FOR DETECTING AUTOANTIBODIES TO ANTI-TNFα DRUGS |
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- 2013-11-27 EP EP13820955.6A patent/EP2926136A2/en not_active Withdrawn
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- 2013-11-27 HK HK16103834.6A patent/HK1215969A1/zh unknown
- 2013-11-27 MX MX2015006852A patent/MX2015006852A/es unknown
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2015
- 2015-05-25 IL IL238995A patent/IL238995A0/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011056590A1 (en) * | 2009-10-26 | 2011-05-12 | Prometheus Laboratories Inc. | Assays for the detection of anti-tnf drugs and autoantibodies |
| WO2011135024A1 (en) * | 2010-04-29 | 2011-11-03 | Biomedical Diagnostics Sa | Methods for detecting antibodies |
| CN103782172A (zh) * | 2011-07-06 | 2014-05-07 | 雀巢产品技术援助有限公司 | 检测针对使用TNFα的生物疗法的中和性自体抗体的测定法 |
Non-Patent Citations (1)
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| KLAUS BENDTZEN 等: "Individualized Monitoring of Drug Bioavailability and Immunogenicity in Rheumatoid Arthritis Patients Treated With the Tumor Necrosis Factor α Inhibitor Infliximab", 《ARTHRITIS & RHEUMATISM》 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109791142A (zh) * | 2016-07-08 | 2019-05-21 | W 健康公司 | 用于确定样品中治疗性单克隆抗体及其相应抗药物抗体的量的通用测定 |
| CN109791142B (zh) * | 2016-07-08 | 2022-11-29 | W 健康公司 | 用于确定样品中治疗性单克隆抗体及其相应抗药物抗体的量的通用测定 |
| CN110546506A (zh) * | 2017-03-31 | 2019-12-06 | 埃博灵克斯股份有限公司 | 改进的免疫原性测定法 |
| CN110546506B (zh) * | 2017-03-31 | 2023-04-04 | 埃博灵克斯股份有限公司 | 改进的免疫原性测定法 |
| US12480957B2 (en) | 2017-03-31 | 2025-11-25 | Ablynx N.V. | Method of screening for anti-drug antibodies against immunoglobulin single variable domain-based drugs |
| CN114902052A (zh) * | 2020-01-02 | 2022-08-12 | 豪夫迈·罗氏有限公司 | Ada应答特异性化测定 |
| CN111024958A (zh) * | 2020-03-11 | 2020-04-17 | 同昕生物技术（北京）有限公司 | 用于检测单抗药物和抗单抗药物抗体的试剂及其应用 |
| CN117871856A (zh) * | 2023-12-15 | 2024-04-12 | 首都医科大学附属北京地坛医院 | 可溶性因子在无症状神经梅毒检测中的应用 |
Also Published As
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| CA2892766A1 (en) | 2014-06-05 |
| WO2014083520A3 (en) | 2014-07-31 |
| EP2926136A2 (en) | 2015-10-07 |
| MX2015006852A (es) | 2015-09-16 |
| SG11201504097PA (en) | 2015-06-29 |
| HK1215969A1 (zh) | 2016-09-30 |
| BR112015012482A2 (pt) | 2017-07-11 |
| KR20150088890A (ko) | 2015-08-03 |
| WO2014083520A2 (en) | 2014-06-05 |
| IL238995A0 (en) | 2015-07-30 |
| SG10201703210XA (en) | 2017-06-29 |
| RU2015125739A (ru) | 2017-01-13 |
| JP2016502091A (ja) | 2016-01-21 |
| AU2013350817A1 (en) | 2015-06-11 |
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