HK1212943A1 - 以沉澱過程產生藥物顆粒的反應器 - Google Patents

以沉澱過程產生藥物顆粒的反應器

Info

Publication number
HK1212943A1
HK1212943A1 HK16100923.4A HK16100923A HK1212943A1 HK 1212943 A1 HK1212943 A1 HK 1212943A1 HK 16100923 A HK16100923 A HK 16100923A HK 1212943 A1 HK1212943 A1 HK 1212943A1
Authority
HK
Hong Kong
Prior art keywords
reactor
precipitation process
producing pharmaceutical
pharmaceutical particles
particles
Prior art date
Application number
HK16100923.4A
Other languages
English (en)
Inventor
桑凱特‧甘迪
卡倫‧莫拉萊達
雅德維加‧雅霍維奇
邁克爾‧祖蓬
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mannkind Corp filed Critical Mannkind Corp
Publication of HK1212943A1 publication Critical patent/HK1212943A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0053—Details of the reactor
    • B01J19/0066—Stirrers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D43/00—Separating particles from liquids, or liquids from solids, otherwise than by sedimentation or filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/27—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices
    • B01F27/271—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator
    • B01F27/2711—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator provided with intermeshing elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18—Stationary reactors having moving elements inside

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Accessories For Mixers (AREA)
HK16100923.4A 2009-11-02 2016-01-28 以沉澱過程產生藥物顆粒的反應器 HK1212943A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25731109P 2009-11-02 2009-11-02
US38466210P 2010-09-20 2010-09-20

Publications (1)

Publication Number Publication Date
HK1212943A1 true HK1212943A1 (zh) 2016-06-24

Family

ID=43922631

Family Applications (2)

Application Number Title Priority Date Filing Date
HK13100309.1A HK1173695A1 (zh) 2009-11-02 2013-01-09 以沉澱過程產生藥物顆粒的反應器
HK16100923.4A HK1212943A1 (zh) 2009-11-02 2016-01-28 以沉澱過程產生藥物顆粒的反應器

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK13100309.1A HK1173695A1 (zh) 2009-11-02 2013-01-09 以沉澱過程產生藥物顆粒的反應器

Country Status (14)

Country Link
US (4) US8491848B2 (zh)
EP (1) EP2496339B1 (zh)
JP (2) JP5981343B2 (zh)
KR (1) KR101907699B1 (zh)
CN (2) CN102596379B (zh)
AU (1) AU2010313177B2 (zh)
BR (1) BR112012011591B1 (zh)
CA (2) CA2979182C (zh)
HK (2) HK1173695A1 (zh)
IL (1) IL219305B (zh)
MX (1) MX2012005091A (zh)
RU (2) RU2553881C2 (zh)
SG (1) SG10201406836SA (zh)
WO (1) WO2011053963A1 (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010125558A1 (en) * 2009-04-28 2010-11-04 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), The Volcani Center Emulsions, emulsifier, method of use and production process
CN102596379B (zh) 2009-11-02 2015-04-01 曼康公司 以沉淀过程产生药物颗粒的反应器
EP2529829B1 (de) * 2011-06-01 2013-10-16 Vakumix Rühr- und Homogenisiertechnik Aktiengesellschaft Dispergierrotor zum Homogenisieren fließfähiger Medien
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US8884050B2 (en) * 2012-04-11 2014-11-11 The Procter & Gamble Company Process for production of acrylic acid or its derivatives from hydroxypropionic acid or its derivatives
EP2868369B1 (en) 2013-11-01 2016-05-25 Umicore AG & Co. KG In-line rotor-stator disperser and method
DE102016102728A1 (de) * 2015-08-13 2017-02-16 Netzsch-Feinmahltechnik Gmbh Vorrichtung und Verfahren zum Dispergieren mindestens einer Substanz in einem Fluid
JP2019504684A (ja) * 2016-01-29 2019-02-21 マンカインド コーポレイション 乾燥粉末吸入器
JP7065580B2 (ja) * 2017-09-29 2022-05-12 株式会社明治 微粒化装置
JP7049798B2 (ja) * 2017-09-29 2022-04-07 株式会社明治 微粒化装置
CN107661705A (zh) * 2017-10-16 2018-02-06 江浩 一种管线式流体物料处理机
FR3077011B1 (fr) * 2018-01-24 2020-02-14 Capsum Dispositif de production d'une dispersion, ensemble et procede associes
KR102054426B1 (ko) * 2019-02-26 2019-12-10 캐비트론 주식회사 가스입구를 구비한 균질기
KR102181672B1 (ko) * 2019-03-14 2020-11-23 캐비트론 주식회사 균질기를 이용한 폴리머 분산 시스템
KR102226886B1 (ko) * 2019-03-14 2021-03-11 캐비트론 주식회사 균질기를 이용한 파우더 분산 시스템
RU2765953C1 (ru) * 2020-12-28 2022-02-07 Общество с ограниченной ответственностью "АГРО ЛЭНД" Растворный узел для приготовления жидких комплексных удобрений
CN114887569B (zh) * 2022-05-23 2023-10-03 南通富莱克流体装备有限公司 气液固超重力强化反应器

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH517515A (de) * 1970-01-30 1972-01-15 Bayer Ag Vorrichtung zur Herstellung von Emulsionen bzw. Suspensionen
DE3009233C2 (de) * 1980-03-11 1984-10-25 Supraton F.J. Zucker GmbH, 4040 Neuss Mischvorrichtung
DE3611048C2 (de) * 1986-04-02 1997-10-23 Gyproc Gmbh Baustoffproduktion Mischer
JPH02144136A (ja) * 1988-11-25 1990-06-01 Ebara Corp 乳化分散機
DE4004477A1 (de) * 1990-02-14 1991-08-22 Schering Ag Verfahren zur herstellung von loesungen oligomerer methylaluminoxane
US6331318B1 (en) * 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
RU2021006C1 (ru) * 1991-06-21 1994-10-15 Хабаровский станкостроительный завод Роторный гидроударный диспергатор
US5352461A (en) 1992-03-11 1994-10-04 Pharmaceutical Discovery Corporation Self assembling diketopiperazine drug delivery system
DK150692A (da) * 1992-12-16 1994-06-17 Niro Holding As Fremgangsmåde ved injektion af et første fluidum i et andet fluidum og apparat til udøvelse af fremgangsmåden
SE503898C2 (sv) * 1994-10-25 1996-09-30 Tetra Laval Holdings & Finance Blandare för blandning av vätskor eller suspensioner samt förfarande för blandning
JPH08141378A (ja) * 1994-11-25 1996-06-04 Nittetsu Mining Co Ltd 乳化分散装置
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
JP3255072B2 (ja) * 1997-02-17 2002-02-12 日本ピー・エム・シー株式会社 ロジン系物質の水性エマルションの製造方法、その水性エマルション組成物及びサイズ剤
GB2308076B (en) * 1997-04-11 1998-04-22 Tecexec Limited A mixing apparatus
GB9818021D0 (en) * 1998-08-18 1998-10-14 Nycomed Imaging As Apparatus
RU2144423C1 (ru) * 1998-09-01 2000-01-20 Фомин Владимир Михайлович Способ обработки жидкотекучих сред в роторно-пульсационном акустическом аппарате
ATE545652T1 (de) * 1999-06-29 2012-03-15 Mannkind Corp Reinigung und stabilisierung von proteinen und peptiden in pharmaceutischen agentien
US6471392B1 (en) * 2001-03-07 2002-10-29 Holl Technologies Company Methods and apparatus for materials processing
RU2166987C1 (ru) * 2000-01-10 2001-05-20 ООО "Альфа-Компани" Кавитационный аппарат
EP1436057B1 (en) * 2001-10-17 2006-04-19 E.I. du Pont de Nemours and Company Rotor-stator apparatus and process for the formation of particles
TW538817U (en) * 2002-09-25 2003-06-21 Ind Tech Res Inst Reactor for producing ultra fine particles
UA64606C2 (en) * 2003-07-15 2006-07-17 Inst Technical Thermal Physics Rotary pulsating apparatus
US7052172B2 (en) * 2003-09-15 2006-05-30 Omni International, Inc. Combination low-shear mixer and high-shear homogenizer
CA2575692C (en) * 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
KR20130066695A (ko) * 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
CN104324362B (zh) 2005-09-14 2018-04-24 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
EP1790615A1 (en) * 2005-11-29 2007-05-30 Trading engineering technologies LLC Device for the preparation of precipitated calcium carbonate
ES2357009T3 (es) * 2005-12-05 2011-04-15 Buss-Sms-Canzler Gmbh Reactor de gran volumen o evaporador de película delgada con un equipo de premezcla.
US8283393B2 (en) * 2006-12-19 2012-10-09 Dow Global Technologies Llc Device for producing dispersions and method of producing dispersions
RU2467741C2 (ru) * 2007-10-24 2012-11-27 Маннкайнд Корпорейшн Доставка активных веществ
KR101736535B1 (ko) * 2007-10-24 2017-05-16 맨카인드 코포레이션 Ｇｌｐ-1에 의한 유해 효과의 예방 방법
RU2357791C1 (ru) * 2007-11-22 2009-06-10 Александр Дмитриевич Петраков Роторный гидродинамический кавитационный аппарат
CN102596379B (zh) 2009-11-02 2015-04-01 曼康公司 以沉淀过程产生药物颗粒的反应器

Also Published As

Publication number Publication date
RU2012120395A (ru) 2013-12-10
US11103847B2 (en) 2021-08-31
IL219305B (en) 2018-04-30
MX2012005091A (es) 2012-06-19
CA2779614C (en) 2017-10-31
US20110105719A1 (en) 2011-05-05
CA2979182C (en) 2021-03-02
CN102596379A (zh) 2012-07-18
JP5981343B2 (ja) 2016-08-31
JP6097858B2 (ja) 2017-03-15
EP2496339B1 (en) 2019-06-26
RU2553881C2 (ru) 2015-06-20
CA2979182A1 (en) 2011-05-05
BR112012011591A2 (pt) 2018-09-11
IL219305A0 (en) 2012-06-28
BR112012011591B1 (pt) 2020-02-27
CA2779614A1 (en) 2011-05-05
CN104801215A (zh) 2015-07-29
US20130296566A1 (en) 2013-11-07
JP2016166199A (ja) 2016-09-15
RU2673525C2 (ru) 2018-11-27
EP2496339A4 (en) 2015-12-16
EP2496339A1 (en) 2012-09-12
US8491848B2 (en) 2013-07-23
KR101907699B1 (ko) 2018-10-12
RU2015113474A3 (zh) 2018-09-28
SG10201406836SA (en) 2014-12-30
JP2013509299A (ja) 2013-03-14
RU2015113474A (ru) 2015-11-10
WO2011053963A1 (en) 2011-05-05
AU2010313177A1 (en) 2012-05-10
HK1173695A1 (zh) 2013-05-24
KR20120091277A (ko) 2012-08-17
CN102596379B (zh) 2015-04-01
CN104801215B (zh) 2017-11-17
US20180193813A1 (en) 2018-07-12
US20210362122A1 (en) 2021-11-25
AU2010313177B2 (en) 2015-04-30

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