HK1209778A1 - Blood test prototypes and methods for the detection of circulating tumor and endothelial cells - Google Patents

Blood test prototypes and methods for the detection of circulating tumor and endothelial cells

Info

Publication number
HK1209778A1
HK1209778A1 HK15110407.9A HK15110407A HK1209778A1 HK 1209778 A1 HK1209778 A1 HK 1209778A1 HK 15110407 A HK15110407 A HK 15110407A HK 1209778 A1 HK1209778 A1 HK 1209778A1
Authority
HK
Hong Kong
Prior art keywords
detection
methods
endothelial cells
blood test
circulating tumor
Prior art date
Application number
HK15110407.9A
Other languages
English (en)
Chinese (zh)
Inventor
Wen-Tien Chen
Lee Chen
Che Chen
Original Assignee
Vitatex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitatex Inc filed Critical Vitatex Inc
Publication of HK1209778A1 publication Critical patent/HK1209778A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0093—Purging against cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sustainable Development (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK15110407.9A 2003-10-31 2015-10-22 Blood test prototypes and methods for the detection of circulating tumor and endothelial cells HK1209778A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51657103P 2003-10-31 2003-10-31

Publications (1)

Publication Number Publication Date
HK1209778A1 true HK1209778A1 (en) 2016-04-08

Family

ID=34549552

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110407.9A HK1209778A1 (en) 2003-10-31 2015-10-22 Blood test prototypes and methods for the detection of circulating tumor and endothelial cells

Country Status (7)

Country Link
EP (1) EP1706720A4 (de)
JP (1) JP2007526761A (de)
CN (2) CN104531529A (de)
AU (1) AU2004286307A1 (de)
CA (1) CA2544373A1 (de)
HK (1) HK1209778A1 (de)
WO (1) WO2005043121A2 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6913697B2 (en) 2001-02-14 2005-07-05 Science & Technology Corporation @ Unm Nanostructured separation and analysis devices for biological membranes
EP1569510B1 (de) 2002-09-27 2011-11-02 The General Hospital Corporation Mikrofluidische vorrichtung zur zelltrennung und verwendungen davon
WO2006031524A2 (en) 2004-09-10 2006-03-23 The Regents Of The Unversity Of Colorado Early detection of hemangiosarcoma and angiosarcoma
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US7769547B2 (en) * 2005-11-01 2010-08-03 David S. Alberts Karyometry-based method for prediction of cancer event recurrence
ATE475884T1 (de) * 2006-04-18 2010-08-15 Wellstat Biologics Corp Detektion von zirkulierenden endothelzellen
US20080070792A1 (en) 2006-06-14 2008-03-20 Roland Stoughton Use of highly parallel snp genotyping for fetal diagnosis
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
US8372584B2 (en) 2006-06-14 2013-02-12 The General Hospital Corporation Rare cell analysis using sample splitting and DNA tags
EP1867995A1 (de) * 2006-06-15 2007-12-19 Cézanne S.A.S. In-vitro-Verfahren zur Diagnose und Überwachung von metastasiertem Blasenkrebs durch Verwendung der MMP-7-Bestimmung im Blutkreislauf von Patienten
CN101896818B (zh) * 2007-12-10 2016-01-20 霍夫曼-拉罗奇有限公司 作为癌症的标记物的Seprase
EP2334812B1 (de) 2008-09-20 2016-12-21 The Board of Trustees of The Leland Stanford Junior University Nichtinvasive diagnose von fötaler aneuploidie mittels sequenzieren
ITCZ20090001A1 (it) * 2009-01-13 2010-07-14 Natalia Malara Isolamento e messa in coltura di cellule epiteliali tumorali dal sangue e dai suoi derivati in pazienti affetti da cancro epiteliale solido
EP2363501A1 (de) * 2010-03-02 2011-09-07 Universitätsklinikum Hamburg-Eppendorf Verfahren zur Isolierung von Zielzellen
CN102213722B (zh) * 2010-04-06 2014-03-12 北京蛋白质组研究中心 一种检测蛋白表达水平的试剂盒在制备诊断肝细胞癌的试剂盒中的应用
BR112013001136B1 (pt) 2010-07-16 2020-12-15 Stichting Vumc Processos de análise para a presença de um marcador de câncer, do estágio da doença ou da eficácia de um tratamento de câncer, e dispositivo para diagnóstico de câncer
US10174365B2 (en) 2011-03-18 2019-01-08 Stichting Vu-Vumc Method of analysing a blood sample of a subject for the presence of a disease marker
EP2720039B1 (de) * 2011-06-13 2017-07-26 Hitachi Chemical Company, Ltd. Mittel zur verbesserung einer krebszellanhaftung
MX2014000095A (es) * 2011-07-07 2014-05-28 Janssen Diagnostics Llc Método de análisis de trastornos cardiovasculares y usos del mismo.
US9555137B2 (en) 2011-07-08 2017-01-31 Sloan-Kettering Institute For Cancer Research Uses of labeled HSP90 inhibitors
JP5834559B2 (ja) * 2011-07-12 2015-12-24 コニカミノルタ株式会社 目的細胞の検査方法
JP6208473B2 (ja) 2012-06-20 2017-10-04 アークレイ株式会社 血液成分を含む試料の処理方法
EP2919910B1 (de) * 2012-11-09 2017-12-20 Roche Diagnostics GmbH In-vitro-erfassung und -analyse zirkulierender tumorzellen
CA2892222C (en) * 2012-11-20 2021-02-02 The Trustees Of Columbia University In The City Of New York Medical apparatus and method for collecting biological samples
WO2014120265A1 (en) * 2013-02-02 2014-08-07 Duke University Method of isolating circulating tumor cells
KR101922322B1 (ko) * 2014-07-22 2018-11-26 가부시키가이샤 간멘에키켄큐쇼 말초 순환 암세포의 검출 방법 및 검출 장치
KR102421024B1 (ko) * 2015-01-21 2022-07-14 에이전시 포 사이언스, 테크놀로지 앤드 리서치 크기에 기초한 희귀 세포의 회수를 위한 칼럼 기반 장치 및 방법, 및 이의 용도
JP6901253B2 (ja) * 2015-10-21 2021-07-14 株式会社日本触媒 接着性細胞培養用基材、ならびにこれを利用した細胞培養容器および細胞培養方法
CN105420088B (zh) * 2015-11-11 2017-12-29 深圳市达科为生物工程有限公司 一种细胞分离管
ES2871137T3 (es) * 2015-12-14 2021-10-28 Quanta Matrix Co Ltd Método de diferenciación de células particulares a partir de la mezcla de células heterogéneas
JP6518985B2 (ja) * 2016-09-29 2019-05-29 住友ゴム工業株式会社 がん細胞捕捉方法
WO2018085070A1 (en) * 2016-11-02 2018-05-11 Emd Millipore Corporation Container for separating microcarriers from cell culture fluids
AU2017379367B2 (en) 2016-12-20 2023-12-07 Sangui Bio Pty. Ltd Blood profiling with protease inhibitors
CN108220233B (zh) * 2016-12-21 2021-07-09 上海透景诊断科技有限公司 细胞分离器具表面处理方法、相关器具、外周血稀有细胞或循环肿瘤细胞快速高效分离方法
EP3342485B1 (de) * 2017-01-02 2020-07-08 Thinxxs Microtechnology Ag Halterung für reagenzträgerelemente
CN106754650B (zh) * 2017-02-24 2018-10-02 哈尔滨中科赛恩斯生物技术有限公司 一种骨髓来源的内皮祖细胞培养方法
CN106840816A (zh) * 2017-03-14 2017-06-13 骏实生物科技(上海)有限公司 一种全自动循环肿瘤细胞阴性富集装置
JP7278595B2 (ja) * 2017-03-16 2023-05-22 ユニベルシテ リブレ デ ブリュッセル Ｃｄ３２１マーカーの発現に基づく循環腫瘍細胞の検出、定量化、及び／又は単離
US11525829B2 (en) * 2017-08-02 2022-12-13 Hemosmart Medical Technology Ltd. Method for capturing target cells or molecules in solution
EP3662052A4 (de) * 2017-08-02 2021-03-24 Hemosmart MedicalTechnology Ltd. Funktionalisiertes netz und fluidische vorrichtung zum einfangen von zellen oder molekülen in lösung
CN108031614B (zh) * 2017-12-14 2020-04-17 四川福德机器人股份有限公司 一种燃气表的涂胶自动补偿方法及采用该方法的装置
MX2020010275A (es) * 2018-03-30 2020-11-06 Exosomics S P A Uso de fibras huecas para obtener sangre o un derivado sanguineo empobrecido de celulas sanguineas y plaquetas derivadas de vesiculas extracelulares.
CN109294973A (zh) * 2018-10-18 2019-02-01 重庆医科大学 一种基于磁珠法阴性去除血尿白细胞富集上皮细胞的方法
CN109887542A (zh) * 2019-02-12 2019-06-14 嘉兴海云惠智医疗科技有限公司 一种基于云计算的肿瘤个体化基因检测智能解读系统
JP6886667B2 (ja) * 2019-03-27 2021-06-16 住友ゴム工業株式会社 がん細胞捕捉方法
CN111751543A (zh) * 2019-03-27 2020-10-09 南方医科大学南方医院 一种稀有肿瘤细胞富集方法及试剂盒
CN111235021B (zh) * 2020-03-06 2022-09-27 大连海事大学 一种双液相外周血中循环肿瘤细胞分离与检测装置及方法
CN112255408B (zh) * 2020-10-16 2023-04-14 牡丹江医学院 一种肿瘤生物标志物及肿瘤检测试剂盒
CN113117359B (zh) * 2021-03-05 2022-08-26 湘雅生物医药(湖州)有限公司 一种用于胶原蛋白提取用的无菌式蒸馏瓶
CN113049344B (zh) * 2021-04-20 2022-02-01 深圳天烁生物科技有限公司 细胞染色的质控品制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4092246A (en) * 1975-05-16 1978-05-30 Abcor, Inc. Helically wound blood filter
US4829000A (en) * 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US5147797A (en) * 1987-08-25 1992-09-15 Regents Of The University Of Minnesota Polypeptides with fibronectin activity
EP0784499A4 (de) * 1992-09-11 2000-03-29 Xenogenex Inc Kunstlebergerät sowie methode
FI93742C (fi) * 1992-10-23 1995-05-26 Elias Hakalehto Menetelmä ja laite solujen osoittamiseksi
EP0727481B1 (de) * 1995-02-16 2003-04-16 Forschungszentrum Jülich Gmbh Verfahren zur Kultivierung von Organfunktionszellen
US5840514A (en) * 1996-11-21 1998-11-24 The Regents Of The University Of Michigan Methods of testing cancer and anticancer drugs
GB9704444D0 (en) * 1997-03-04 1997-04-23 Isis Innovation Non-invasive prenatal diagnosis
JPH11127843A (ja) * 1997-10-27 1999-05-18 Sumitomo Bakelite Co Ltd 培養用着色容器
US6060317A (en) * 1998-08-11 2000-05-09 The United States Of America As Represented By The Department Of Health And Human Services Method of transducing mammalian cells, and products related thereto
EP1114063A2 (de) * 1998-09-14 2001-07-11 Lars Ostergaard Pedersen Verfahren zur produktion von funktionellen proteinen der immunglobulinsuperfamilie
CN1484709A (zh) * 2000-09-09 2004-03-24 ŦԼ������ѧ�о������ 分离转移性癌细胞的方法与组合物,及其在检测癌转移性上的应用
GB0025245D0 (en) * 2000-10-14 2000-11-29 Lee Helen Multiple target detection
CN1118563C (zh) * 2000-12-08 2003-08-20 中国医学科学院血液学研究所 中空纤维模拟骨髓造血装置
WO2003035888A1 (en) * 2001-08-28 2003-05-01 Wen-Tien Chen Cell separation matrix
WO2003023059A2 (de) * 2001-09-06 2003-03-20 Adnagen Ag Verfahren und kit zur diagnostik oder behandlungskontrolle von darmkrebs

Also Published As

Publication number Publication date
CA2544373A1 (en) 2005-05-12
CN104531529A (zh) 2015-04-22
CN1922304A (zh) 2007-02-28
EP1706720A4 (de) 2007-02-28
WO2005043121A3 (en) 2006-08-24
AU2004286307A1 (en) 2005-05-12
WO2005043121A2 (en) 2005-05-12
EP1706720A2 (de) 2006-10-04
JP2007526761A (ja) 2007-09-20

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