EP1613959A4 - Verfahren zum nachweis von krebszellen in biologischen proben - Google Patents

Verfahren zum nachweis von krebszellen in biologischen proben

Info

Publication number
EP1613959A4
EP1613959A4 EP04725136A EP04725136A EP1613959A4 EP 1613959 A4 EP1613959 A4 EP 1613959A4 EP 04725136 A EP04725136 A EP 04725136A EP 04725136 A EP04725136 A EP 04725136A EP 1613959 A4 EP1613959 A4 EP 1613959A4
Authority
EP
European Patent Office
Prior art keywords
methods
cancer cells
biological samples
detecting cancer
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04725136A
Other languages
English (en)
French (fr)
Other versions
EP1613959A2 (de
Inventor
Michal Daniely
Tal Kaplan
Eran Kaplan
Avner Freiberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioview Ltd
Original Assignee
Bioview Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioview Ltd filed Critical Bioview Ltd
Publication of EP1613959A2 publication Critical patent/EP1613959A2/de
Publication of EP1613959A4 publication Critical patent/EP1613959A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
EP04725136A 2003-04-04 2004-04-01 Verfahren zum nachweis von krebszellen in biologischen proben Withdrawn EP1613959A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45999203P 2003-04-04 2003-04-04
US10/771,440 US20040197839A1 (en) 2003-04-04 2004-02-05 Methods of detecting cancer cells in biological samples
PCT/IL2004/000305 WO2004086937A2 (en) 2003-04-04 2004-04-01 Methods of detecting cancer cells in biological samples

Publications (2)

Publication Number Publication Date
EP1613959A2 EP1613959A2 (de) 2006-01-11
EP1613959A4 true EP1613959A4 (de) 2007-08-29

Family

ID=33101396

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04725136A Withdrawn EP1613959A4 (de) 2003-04-04 2004-04-01 Verfahren zum nachweis von krebszellen in biologischen proben

Country Status (3)

Country Link
US (1) US20040197839A1 (de)
EP (1) EP1613959A4 (de)
WO (1) WO2004086937A2 (de)

Families Citing this family (25)

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CA2350692A1 (en) * 1998-10-29 2000-05-11 Cell Works Inc. Multiple marker characterization of single cells
WO2007080583A2 (en) * 2006-01-10 2007-07-19 Applied Spectral Imaging Ltd. Methods and systems for analyzing biological samples
ES2553637T3 (es) 2006-03-06 2015-12-10 Zetiq Technologies Ltd. Métodos para identificar un fenotipo celular
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
US8372584B2 (en) 2006-06-14 2013-02-12 The General Hospital Corporation Rare cell analysis using sample splitting and DNA tags
CN104849228B (zh) * 2006-06-29 2018-04-13 皇家飞利浦电子股份有限公司 使用基于uv 光的dna 成像细胞术来检测和/或诊断癌症的体外方法
US8060348B2 (en) * 2006-08-07 2011-11-15 General Electric Company Systems for analyzing tissue samples
US8131476B2 (en) * 2006-08-07 2012-03-06 General Electric Company System and method for co-registering multi-channel images of a tissue micro array
US20090208965A1 (en) * 2006-10-25 2009-08-20 Ikonisys, Inc. Automated method for detecting cancers and high grade hyperplasias
WO2009047756A2 (en) * 2007-10-11 2009-04-16 Bioview Ltd. Methods and kits for diagnosing lung cancer
US7787112B2 (en) 2007-10-22 2010-08-31 Visiongate, Inc. Depth of field extension for optical tomography
US8090183B2 (en) 2009-03-12 2012-01-03 Visiongate, Inc. Pattern noise correction for pseudo projections
US8254023B2 (en) 2009-02-23 2012-08-28 Visiongate, Inc. Optical tomography system with high-speed scanner
CN102576024B (zh) 2009-05-19 2016-10-26 泽蒂克科技有限公司 宫颈癌细胞和/或组织的鉴别染色的试剂盒和方法
CN102183395B (zh) * 2011-03-11 2013-08-21 大连医科大学 利用组织封固剂转移石蜡切片、冰冻切片的方法
WO2012152747A2 (en) 2011-05-09 2012-11-15 Ventana Medical Systems, Inc. Spectral imaging for measurement of nuclear pathology features in cancer cells prepared for in situ analysis
JP5372068B2 (ja) * 2011-05-20 2013-12-18 キヤノン株式会社 撮像システム、画像処理装置
JP5812095B2 (ja) * 2011-09-09 2015-11-11 コニカミノルタ株式会社 生体物質検出方法
CN103529037B (zh) * 2013-10-09 2016-03-16 中国科学院合肥物质科学研究院 一种黄连木植株性别鉴定方法
CN105987838A (zh) * 2015-02-06 2016-10-05 中国科学院上海生命科学研究院 一种组织切片可视化处理的方法
US11069054B2 (en) 2015-12-30 2021-07-20 Visiongate, Inc. System and method for automated detection and monitoring of dysplasia and administration of immunotherapy and chemotherapy
WO2018078448A1 (en) * 2016-10-27 2018-05-03 Scopio Labs Ltd. Methods and systems for diagnostic platform
CN107576551B (zh) * 2017-06-30 2020-08-04 曾峰 脱落细胞在冰冻切片中的制备方法
EP3884259A1 (de) * 2018-11-20 2021-09-29 Ventana Medical Systems, Inc. Verfahren und systeme zur herstellung und analyse von zellulären proben für morphologische merkmale und biomarkerexpression
US20230204582A1 (en) * 2020-05-28 2023-06-29 Cytobay Inc. Cytopathological staining

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003040064A2 (en) * 2001-11-07 2003-05-15 Bioview Ltd. Kits and methods for preparing cell samples optimized for dual staining

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US6418236B1 (en) * 1999-06-24 2002-07-09 Chromavision Medical Systems, Inc. Histological reconstruction and automated image analysis
DE19613691A1 (de) * 1996-04-05 1997-10-09 Boehringer Ingelheim Int Arzneimittel für die Behandlung von Tumorerkrankungen
US6174681B1 (en) * 1999-03-05 2001-01-16 Mayo Foundation For Medical Education And Research Method and probe set for detecting cancer
DE10063179A1 (de) * 2000-12-18 2002-06-20 Bayer Ag Verfahren zur spezifischen Detektion von Tumorzellen und ihren Vorstufen in Gebärmutterhalsabstrichen durch simultane Messung von mindestens zwei verschiedenen molekularen Markern

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003040064A2 (en) * 2001-11-07 2003-05-15 Bioview Ltd. Kits and methods for preparing cell samples optimized for dual staining

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BIELORAI BELLA ET AL: "Combined analysis of morphology and fluorescence in situ hybridization in follow-up of minimal residual disease in a child with Philadelphia-positive acute lymphoblastic leukemia", CANCER GENETICS AND CYTOGENETICS, vol. 138, no. 1, 1 October 2002 (2002-10-01), pages 64 - 68, XP002436533, ISSN: 0165-4608 *
DANIELY M ET AL: "Combined analysis of morphology and FISH for the monitoring of bladder cancer.", ANNALES DE GENETIQUE, vol. 46, no. 2-3, September 2003 (2003-09-01), & FOURTH EUROPEAN CYTOGENETICS CONFERENCE; BOLOGNA, ITALY; SEPTEMBER 06-09, 2003, pages 153, XP009084847, ISSN: 0003-3995 *
HARDAN IZHAR ET AL: "Detection of 13q Deletion in the Bone Marrow Cells of Patients with Multiple Myeloma Using Combined Morphological and FISH Analysis.", BLOOD, vol. 100, no. 11, 16 November 2002 (2002-11-16), & 44TH ANNUAL MEETING OF THE AMERICAN SOCIETY OF HEMATOLOGY; PHILADELPHIA, PA, USA; DECEMBER 06-10, 2002, pages Abstract No. 1522, XP009084849, ISSN: 0006-4971 *
INOUE T ET AL: "Chromosomal numerical aberrations of exfoliated cells in the urine detected by fluorescence in situ hybridization: Clinical implication for the detection of bladder cancer", UROLOGICAL RESEARCH, vol. 28, no. 1, January 2000 (2000-01-01), pages 57 - 61, XP002436532, ISSN: 0300-5623 *
KAPLINSKI C ET AL: "Increased accuracy of leukemia diagnosis by combined analysis of morphology and FISH using the Duet automatic cell scanning system.", EUROPEAN JOURNAL OF HUMAN GENETICS, vol. 10, no. Supplement 1, 2002, & EUROPEAN HUMAN GENETICS CONFERENCE 2002 IN CONJUNCTION WITH THE EUROPEAN MEETING ON PSYCHOSOCIAL ASP; STRASBOURG, FRANCE; MAY 25-28, 2002, pages 90, XP009084857, ISSN: 1018-4813 *

Also Published As

Publication number Publication date
EP1613959A2 (de) 2006-01-11
WO2004086937A2 (en) 2004-10-14
WO2004086937A3 (en) 2005-03-10
US20040197839A1 (en) 2004-10-07

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