HK1205202A1 - Target detection and signal amplification - Google Patents

Target detection and signal amplification

Info

Publication number
HK1205202A1
HK1205202A1 HK15105637.1A HK15105637A HK1205202A1 HK 1205202 A1 HK1205202 A1 HK 1205202A1 HK 15105637 A HK15105637 A HK 15105637A HK 1205202 A1 HK1205202 A1 HK 1205202A1
Authority
HK
Hong Kong
Prior art keywords
target detection
signal amplification
amplification
target
signal
Prior art date
Application number
HK15105637.1A
Other languages
English (en)
Chinese (zh)
Inventor
Simon Mark Bone
Alison Velyian Todd
Timothy Daniel Meehan
Original Assignee
Speedx Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012902551A external-priority patent/AU2012902551A0/en
Application filed by Speedx Pty Ltd filed Critical Speedx Pty Ltd
Publication of HK1205202A1 publication Critical patent/HK1205202A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/9005—Enzymes with nucleic acid structure; e.g. ribozymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
HK15105637.1A 2012-06-18 2015-06-15 Target detection and signal amplification HK1205202A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2012902551A AU2012902551A0 (en) 2012-06-18 Target detection and signal amplification
AU2012903462A AU2012903462A0 (en) 2012-08-10 Target detection and signal amplification
AU2013202354A AU2013202354A1 (en) 2012-06-18 2013-04-03 Target detection and signal amplification
PCT/AU2013/000651 WO2013188912A1 (fr) 2012-06-18 2013-06-18 Détection de cible et amplification de signal

Publications (1)

Publication Number Publication Date
HK1205202A1 true HK1205202A1 (en) 2015-12-11

Family

ID=49767935

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15105637.1A HK1205202A1 (en) 2012-06-18 2015-06-15 Target detection and signal amplification

Country Status (12)

Country Link
US (1) US9725757B2 (fr)
EP (1) EP2861770B1 (fr)
JP (1) JP6336443B2 (fr)
CN (1) CN104540965B (fr)
AU (2) AU2013202354A1 (fr)
CA (1) CA2876919C (fr)
HK (1) HK1205202A1 (fr)
IL (1) IL236363A0 (fr)
IN (1) IN2015DN00194A (fr)
NZ (1) NZ629701A (fr)
SG (1) SG11201408489PA (fr)
WO (1) WO2013188912A1 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103328654B (zh) 2010-10-27 2017-07-11 哈佛学院院长等 立足点引物双链体的组合物及其使用方法
JP2014531203A (ja) * 2011-09-09 2014-11-27 スピーデクス ピーティーワイ リミテッド 核酸酵素基質
US9476090B2 (en) 2013-05-21 2016-10-25 Stc.Unm Signal propagation biomolecules, devices and methods
AU2015229406C1 (en) 2014-03-11 2021-01-07 President And Fellows Of Harvard College High-throughput and highly multiplexed imaging with programmable nucleic acid probes
GB201415674D0 (en) * 2014-09-04 2014-10-22 Moorlodge Biotech Ventures Ltd Nucleic acid analysis
CN107208160B (zh) 2015-01-30 2023-02-17 哈佛学院院长及董事 无显微镜成像
CN116949140A (zh) * 2016-02-17 2023-10-27 哈佛学院院长及董事 分子编程工具
CN109923213B (zh) 2016-09-20 2023-02-28 哈佛学院院长及董事 分子验证系统
US10934162B2 (en) * 2016-11-15 2021-03-02 The Governors Of The University Of Alberta MicroRNA initiated DNAzyme motor operating in living cells
EP3568492A4 (fr) 2017-01-10 2021-03-17 President and Fellows of Harvard College Amplification de signal multiplexée
JP7486951B2 (ja) * 2017-04-11 2024-05-20 スピーディックス プロプライアタリー リミティド 検出カスケード
CA3058202A1 (fr) * 2017-04-17 2018-10-25 Montana State University Amplification d'adn isotherme de type commutateur presentant un taux d'amplification non lineaire
CN107870242B (zh) * 2017-10-12 2020-02-21 广东省生态环境技术研究所 一种基于核酸适体的荧光检测试剂盒
CN107663530B (zh) * 2017-11-10 2020-07-03 中国海洋大学 一种单链核酸检测试剂盒、方法及其应用
US11981956B2 (en) 2018-01-26 2024-05-14 President And Fellows Of Harvard College Proximity detection methods and compositions
CN108642137B (zh) * 2018-05-21 2021-11-30 福州大学 一种利用回文锁式探针检测肿瘤生物标志物的方法
CN109055609B (zh) * 2018-08-08 2021-10-15 临沂大学 基于t4 dna聚合酶的西瓜花叶病毒检测传感器及其组装方法
CN109097468A (zh) * 2018-08-14 2018-12-28 南通市第人民医院 Opcml基因启动子甲基化水平的检测试剂盒及其应用
CN109283147B (zh) * 2018-09-20 2021-03-16 湖北师范大学 一种检测卡那霉素的均相生物传感方法及其应用
WO2020177059A1 (fr) * 2019-03-04 2020-09-10 Nano And Advanced Materials Institute Limited Système et procédé de détection de métaux lourds et de bactéries dans un analyte
CN110607351B (zh) * 2019-09-20 2022-11-01 济南大学 一种检测尿嘧啶糖基化酶的化学发光生物传感器及其制备方法与应用
WO2021138312A1 (fr) * 2019-12-30 2021-07-08 Ultivue, Inc. Procédés de réduction d'interactions non spécifiques sur des échantillons biologiques
CN112029827A (zh) * 2020-09-04 2020-12-04 重庆工商大学 一种高效率转换率dna纳米探针结构的设计方法
WO2022061166A1 (fr) * 2020-09-17 2022-03-24 Mammoth Biosciences, Inc. Compositions et procédés de détection d'un acide nucléique
CN113234800B (zh) * 2021-05-13 2023-01-10 中山大学 一种黄曲霉毒素m1的检测方法及其应用
WO2022271873A2 (fr) * 2021-06-22 2022-12-29 Mammoth Biosciences, Inc. Dispositif de diagnostic à nucléase programmable
US20230167487A2 (en) 2021-07-12 2023-06-01 Labsimply, Inc. Crispr cascade assay
US11820983B2 (en) 2021-12-13 2023-11-21 Labsimply, Inc. Tuning cascade assay kinetics via molecular design
US20230279375A1 (en) 2021-12-13 2023-09-07 Labsimply, Inc. Signal boost cascade assay
WO2023225651A2 (fr) * 2022-05-19 2023-11-23 Logicink Corporation Détection de séquence cible sans pré-amplification avec lecture colorimétrique
US12091689B2 (en) 2022-09-30 2024-09-17 Vedabio, Inc. Delivery of therapeutics in vivo via a CRISPR-based cascade system
WO2024076473A1 (fr) 2022-10-02 2024-04-11 Vedabio, Inc. Dosages de criblage de dimérisation
US11965205B1 (en) 2022-10-14 2024-04-23 Vedabio, Inc. Detection of nucleic acid and non-nucleic acid target molecules
US12091690B2 (en) 2023-01-07 2024-09-17 Vedabio, Inc. Engineered nucleic acid-guided nucleases
WO2024151493A1 (fr) 2023-01-10 2024-07-18 Vedabio, Inc. Division d'échantillon pour la détection multiplexée d'acides nucléiques sans amplification
CN116286806A (zh) * 2023-03-21 2023-06-23 华中科技大学 具有催化功能的寡核苷酸、核酸电子器件、逻辑门复合物及电路
CN116732211B (zh) * 2023-08-09 2023-10-27 湖南工程学院 基于8-17脱氧核酶与CRISPR-Cas13a反式切割检测牛结核分枝杆菌的探针组及方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5424413A (en) * 1992-01-22 1995-06-13 Gen-Probe Incorporated Branched nucleic acid probes
IL138126A0 (en) * 1998-03-05 2001-10-31 Johnson & Johnson Res Pty Ltd Zymogenic nucleic acid detection methods and related molecules and kits
WO2001096541A2 (fr) * 2000-06-15 2001-12-20 Board Of Regents Ribozymes regules de maniere allosterique
CN1451051A (zh) 2000-06-21 2003-10-22 维珍实验室公司 检测病毒逆转录酶活性
US20040106109A1 (en) * 2001-10-02 2004-06-03 Belly Robert T Detection of ras mutations
EP1814896A4 (fr) * 2004-07-06 2008-07-30 Commercialisation Des Produits Adaptateur d'acide nucleique dependant de la cible
US20060240462A1 (en) * 2005-04-21 2006-10-26 Johnson & Johnson Research Pty Limited Methods for amplification and detection of nucleic acids
US20120101267A1 (en) * 2005-10-07 2012-04-26 Alison Velyian Todd Multicomponent nucleic acid enzymes with cleavage, ligase or other activity and methods for their use
DK2385141T3 (da) * 2005-10-07 2013-10-28 Speedx Pty Ltd Flerkomponentnukleinsyreenzymer og fremgangsmåder til anvendelse heraf
AU2006323930B2 (en) * 2005-12-07 2012-06-21 Janssen Sciences Ireland Uc Methods, plasmid vectors and primers for assessing HIV viral fitness
ZA200901742B (en) * 2006-10-06 2010-06-30 Johnson & Johnson Res Pty Ltd Moleculor switches and methods for their use
WO2008122084A1 (fr) * 2007-04-05 2008-10-16 Johnson & Johnson Research Pty Limited Enzymes et complexes d'acides nucléiques et leurs procédés d'utilisation
CA2950685A1 (fr) * 2007-04-06 2008-10-16 Virco Bvba Dosage permettant la detection de la charge virale du virus respiratoire syncytial (vrs)
JP2010535528A (ja) * 2007-08-13 2010-11-25 ユニバーシティ オブ ストラスクライド 核酸配列の同定
US20110207132A1 (en) * 2008-08-04 2011-08-25 University Of Maryland Probes and methods for detecting analytes
CN102186997B (zh) * 2008-08-15 2014-12-24 卡斯凯德生物体系股份有限公司 检测核酸
WO2012065231A1 (fr) * 2010-11-19 2012-05-24 Speedx Pty Ltd Amplification de signaux
KR101249493B1 (ko) * 2010-11-23 2013-04-01 한국과학기술원 핵산효소-분자비콘을 이용한 핵산의 검출방법
JP2014531203A (ja) * 2011-09-09 2014-11-27 スピーデクス ピーティーワイ リミテッド 核酸酵素基質
US9963738B2 (en) * 2012-02-20 2018-05-08 Speedx Pty Ltd Detection of nucleic acids
US9476090B2 (en) * 2013-05-21 2016-10-25 Stc.Unm Signal propagation biomolecules, devices and methods

Also Published As

Publication number Publication date
NZ629701A (en) 2016-03-31
US20160083785A1 (en) 2016-03-24
US9725757B2 (en) 2017-08-08
AU2013277929A1 (en) 2015-01-22
IN2015DN00194A (fr) 2015-06-12
JP2015523864A (ja) 2015-08-20
EP2861770A1 (fr) 2015-04-22
CN104540965A (zh) 2015-04-22
EP2861770A4 (fr) 2015-12-23
EP2861770B1 (fr) 2018-01-31
WO2013188912A1 (fr) 2013-12-27
CA2876919A1 (fr) 2013-12-27
AU2013277929B2 (en) 2015-07-16
SG11201408489PA (en) 2015-01-29
CA2876919C (fr) 2021-09-14
IL236363A0 (en) 2015-02-26
AU2013202354A1 (en) 2014-01-16
CN104540965B (zh) 2019-06-04
JP6336443B2 (ja) 2018-06-06

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