HK1205202A1 - Target detection and signal amplification - Google Patents

Target detection and signal amplification

Info

Publication number
HK1205202A1
HK1205202A1 HK15105637.1A HK15105637A HK1205202A1 HK 1205202 A1 HK1205202 A1 HK 1205202A1 HK 15105637 A HK15105637 A HK 15105637A HK 1205202 A1 HK1205202 A1 HK 1205202A1
Authority
HK
Hong Kong
Prior art keywords
target detection
signal amplification
amplification
target
signal
Prior art date
Application number
HK15105637.1A
Other languages
English (en)
Chinese (zh)
Inventor
Simon Mark Bone
Alison Velyian Todd
Timothy Daniel Meehan
Original Assignee
Speedx Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012902551A external-priority patent/AU2012902551A0/en
Application filed by Speedx Pty Ltd filed Critical Speedx Pty Ltd
Publication of HK1205202A1 publication Critical patent/HK1205202A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6823Release of bound markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/9005Enzymes with nucleic acid structure; e.g. ribozymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
HK15105637.1A 2012-06-18 2015-06-15 Target detection and signal amplification HK1205202A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2012902551A AU2012902551A0 (en) 2012-06-18 Target detection and signal amplification
AU2012903462A AU2012903462A0 (en) 2012-08-10 Target detection and signal amplification
AU2013202354A AU2013202354A1 (en) 2012-06-18 2013-04-03 Target detection and signal amplification
PCT/AU2013/000651 WO2013188912A1 (en) 2012-06-18 2013-06-18 Target detection and signal amplification

Publications (1)

Publication Number Publication Date
HK1205202A1 true HK1205202A1 (en) 2015-12-11

Family

ID=49767935

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15105637.1A HK1205202A1 (en) 2012-06-18 2015-06-15 Target detection and signal amplification

Country Status (12)

Country Link
US (1) US9725757B2 (es)
EP (1) EP2861770B1 (es)
JP (1) JP6336443B2 (es)
CN (1) CN104540965B (es)
AU (2) AU2013202354A1 (es)
CA (1) CA2876919C (es)
HK (1) HK1205202A1 (es)
IL (1) IL236363A0 (es)
IN (1) IN2015DN00194A (es)
NZ (1) NZ629701A (es)
SG (1) SG11201408489PA (es)
WO (1) WO2013188912A1 (es)

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EP3250716B1 (en) 2015-01-30 2021-07-07 President and Fellows of Harvard College Microscope-free imaging
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US11359229B2 (en) 2016-09-20 2022-06-14 President And Fellows Of Harvard College Molecular verification systems
US10934162B2 (en) * 2016-11-15 2021-03-02 The Governors Of The University Of Alberta MicroRNA initiated DNAzyme motor operating in living cells
JP7116062B2 (ja) 2017-01-10 2022-08-09 プレジデント アンド フェローズ オブ ハーバード カレッジ 多重化シグナル増幅
AU2018252339A1 (en) * 2017-04-11 2019-07-11 Speedx Pty Ltd Detection cascades
US20200048691A1 (en) * 2017-04-17 2020-02-13 Montana State University Switch-like isothermal dna amplification demonstrating a non-linear amplification rate
CN107870242B (zh) * 2017-10-12 2020-02-21 广东省生态环境技术研究所 一种基于核酸适体的荧光检测试剂盒
CN107663530B (zh) * 2017-11-10 2020-07-03 中国海洋大学 一种单链核酸检测试剂盒、方法及其应用
US11981956B2 (en) 2018-01-26 2024-05-14 President And Fellows Of Harvard College Proximity detection methods and compositions
CN108642137B (zh) * 2018-05-21 2021-11-30 福州大学 一种利用回文锁式探针检测肿瘤生物标志物的方法
CN109055609B (zh) * 2018-08-08 2021-10-15 临沂大学 基于t4 dna聚合酶的西瓜花叶病毒检测传感器及其组装方法
CN109097468A (zh) * 2018-08-14 2018-12-28 南通市第人民医院 Opcml基因启动子甲基化水平的检测试剂盒及其应用
CN109283147B (zh) * 2018-09-20 2021-03-16 湖北师范大学 一种检测卡那霉素的均相生物传感方法及其应用
WO2020177059A1 (en) * 2019-03-04 2020-09-10 Nano And Advanced Materials Institute Limited System and method for detecting heavy metals and bacteria in an analyte
CN110607351B (zh) * 2019-09-20 2022-11-01 济南大学 一种检测尿嘧啶糖基化酶的化学发光生物传感器及其制备方法与应用
EP4085154A4 (en) * 2019-12-30 2024-02-21 Ultivue, Inc. METHODS FOR REDUCING NON-SPECIFIC INTERACTIONS IN BIOLOGICAL SAMPLES
CN112029827A (zh) * 2020-09-04 2020-12-04 重庆工商大学 一种高效率转换率dna纳米探针结构的设计方法
WO2022061166A1 (en) * 2020-09-17 2022-03-24 Mammoth Biosciences, Inc. Compositions and methods for detection of a nucleic acid
CN113234800B (zh) * 2021-05-13 2023-01-10 中山大学 一种黄曲霉毒素m1的检测方法及其应用
WO2022271873A2 (en) * 2021-06-22 2022-12-29 Mammoth Biosciences, Inc. Programmable nuclease diagnostic device
US20230167487A2 (en) 2021-07-12 2023-06-01 Labsimply, Inc. Crispr cascade assay
WO2023114090A2 (en) * 2021-12-13 2023-06-22 Labsimply, Inc. Signal boost cascade assay
US11820983B2 (en) 2021-12-13 2023-11-21 Labsimply, Inc. Tuning cascade assay kinetics via molecular design
WO2023225651A2 (en) * 2022-05-19 2023-11-23 Logicink Corporation Pre-amplification-free target sequence detection with colormetric readout
US11982677B2 (en) 2022-10-02 2024-05-14 Vedabio, Inc. Dimerization screening assays
US11965205B1 (en) 2022-10-14 2024-04-23 Vedabio, Inc. Detection of nucleic acid and non-nucleic acid target molecules
CN116286806A (zh) * 2023-03-21 2023-06-23 华中科技大学 具有催化功能的寡核苷酸、核酸电子器件、逻辑门复合物及电路
CN116732211B (zh) * 2023-08-09 2023-10-27 湖南工程学院 基于8-17脱氧核酶与CRISPR-Cas13a反式切割检测牛结核分枝杆菌的探针组及方法

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SG11201400464QA (en) * 2011-09-09 2014-06-27 Speedx Pty Ltd Nucleic acid enzyme substrates
BR112014020422B1 (pt) * 2012-02-20 2021-12-28 Speedx Pty Ltd Método para determinar a presença ou ausência de um polinucleotídeo alvo em uma amostra
US9476090B2 (en) * 2013-05-21 2016-10-25 Stc.Unm Signal propagation biomolecules, devices and methods

Also Published As

Publication number Publication date
IN2015DN00194A (es) 2015-06-12
JP2015523864A (ja) 2015-08-20
EP2861770A1 (en) 2015-04-22
US9725757B2 (en) 2017-08-08
NZ629701A (en) 2016-03-31
WO2013188912A1 (en) 2013-12-27
AU2013277929B2 (en) 2015-07-16
JP6336443B2 (ja) 2018-06-06
EP2861770A4 (en) 2015-12-23
CN104540965A (zh) 2015-04-22
AU2013277929A1 (en) 2015-01-22
IL236363A0 (en) 2015-02-26
AU2013202354A1 (en) 2014-01-16
CA2876919A1 (en) 2013-12-27
EP2861770B1 (en) 2018-01-31
SG11201408489PA (en) 2015-01-29
US20160083785A1 (en) 2016-03-24
CN104540965B (zh) 2019-06-04
CA2876919C (en) 2021-09-14

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