HK1204261A1 - Immunogenic wt-1 peptides and methods of use thereof wt-1 - Google Patents
Immunogenic wt-1 peptides and methods of use thereof wt-1Info
- Publication number
- HK1204261A1 HK1204261A1 HK15104710.4A HK15104710A HK1204261A1 HK 1204261 A1 HK1204261 A1 HK 1204261A1 HK 15104710 A HK15104710 A HK 15104710A HK 1204261 A1 HK1204261 A1 HK 1204261A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- immunogenic
- peptides
- methods
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/59—Reproductive system, e.g. uterus, ovaries, cervix or testes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
- A61K39/001153—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464452—Transcription factors, e.g. SOX or c-MYC
- A61K39/464453—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Hospice & Palliative Care (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261586177P | 2012-01-13 | 2012-01-13 | |
US201261647207P | 2012-05-15 | 2012-05-15 | |
PCT/US2013/021448 WO2013106834A2 (fr) | 2012-01-13 | 2013-01-14 | Peptides wt-1 immunogènes et leurs procédés d'utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1204261A1 true HK1204261A1 (en) | 2015-11-13 |
Family
ID=48782099
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15104710.4A HK1204261A1 (en) | 2012-01-13 | 2015-05-18 | Immunogenic wt-1 peptides and methods of use thereof wt-1 |
Country Status (8)
Country | Link |
---|---|
US (3) | US20150104413A1 (fr) |
EP (2) | EP3520810A3 (fr) |
JP (2) | JP6282598B2 (fr) |
CN (2) | CN104684577B (fr) |
AU (2) | AU2013207669C1 (fr) |
CA (1) | CA2861206C (fr) |
HK (1) | HK1204261A1 (fr) |
WO (1) | WO2013106834A2 (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104684577B (zh) | 2012-01-13 | 2018-05-08 | 纪念斯隆凯特林癌症中心 | 免疫原性wt-1肽及其使用方法 |
KR102208505B1 (ko) | 2012-12-11 | 2021-01-27 | 앨버트 아인슈타인 컬리지 오브 메디신 | 고처리량 수용체:리간드 확인을 위한 방법 |
WO2015164826A2 (fr) | 2014-04-24 | 2015-10-29 | Rhode Island Hospital | Induction par l'aspartate-ss-hydroxylase d'une réponse des cellules t spécifique des épitopes dans les tumeurs |
US10695385B2 (en) | 2015-06-25 | 2020-06-30 | National University Corporation Kobe University | Oral cancer vaccine |
CA2997757A1 (fr) * | 2015-09-10 | 2017-03-16 | Memorial Sloan Kettering Cancer Center | Procedes de traitement du myelome multiple et de la leucemie a plasmocytes par therapie par cellules t |
CN108604257B (zh) | 2015-10-12 | 2022-12-13 | 南托米克斯有限责任公司 | 产生特异性免疫治疗组合物及其相关核酸构建体的方法 |
MA43283B1 (fr) | 2015-11-20 | 2022-08-31 | Memorial Sloan Kettering Cancer Center | Composition pour le traitement du cancer |
WO2017201210A1 (fr) | 2016-05-18 | 2017-11-23 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs des lymphocytes t et leurs procédé d'utilisation |
US11339201B2 (en) | 2016-05-18 | 2022-05-24 | Albert Einstein College Of Medicine | Variant PD-L1 polypeptides, T-cell modulatory multimeric polypeptides, and methods of use thereof |
JP7197481B2 (ja) | 2016-11-30 | 2022-12-27 | アドバクシス, インコーポレイテッド | 反復性がん突然変異を標的とする免疫原性組成物およびその使用の方法 |
AU2017379900A1 (en) | 2016-12-22 | 2019-06-13 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
SG10201914064QA (en) | 2017-01-06 | 2020-03-30 | Eutilex Co Ltd | Anti-human 4-1 bb antibodies and use thereof |
EP3565829A4 (fr) | 2017-01-09 | 2021-01-27 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs de lymphocytes t et leurs procédés d'utilisation |
EP3596118B1 (fr) | 2017-03-15 | 2024-08-21 | Cue Biopharma, Inc. | Procédés pour moduler une réponse immunitaire |
CA3074839A1 (fr) | 2017-09-07 | 2019-03-14 | Cue Biopharma, Inc. | Polypeptide multimere modulateur de lymphocyte t ayant des sites de conjugaison et procedes d'utilisation associes |
EP3707152A4 (fr) * | 2017-11-08 | 2021-12-01 | Advaxis, Inc. | Peptides hétéroclitiques immunogènes issus de protéines associées au cancer et procédés d'utilisation de ces peptides |
WO2019139896A1 (fr) | 2018-01-09 | 2019-07-18 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs de lymphocytes t et leurs procédés d'utilisation |
WO2019227106A1 (fr) * | 2018-05-25 | 2019-11-28 | The Wistar Institute | Néo-antigènes spécifiques d'une tumeur et leurs méthodes d'utilisation |
WO2020132366A2 (fr) * | 2018-12-19 | 2020-06-25 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs des lymphocytes t ayant des sites de conjugaison et procédés d'utilisation associés |
CN110423723A (zh) * | 2019-07-18 | 2019-11-08 | 南方医科大学南方医院 | 一种外周血b细胞系的构建方法及其应用 |
CA3162690A1 (fr) | 2019-12-31 | 2021-07-08 | Minoru S. H. Ko | Administration transitoire basee sur la temperature d'acides nucleiques et de proteines a des cellules et des tissus |
IL296209A (en) | 2020-05-12 | 2022-11-01 | Cue Biopharma Inc | Multimeric t-cell modulatory polypeptides and methods of using them |
JP2023541366A (ja) | 2020-09-09 | 2023-10-02 | キュー バイオファーマ, インコーポレイテッド | 1型真性糖尿病(t1d)を治療するためのmhcクラスii t細胞調節多量体ポリペプチド及びその使用方法 |
Family Cites Families (118)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA8748A (fr) | 1878-05-04 | George W. Ainsworth | Perfectionnements aux sechoirs a linge | |
CA23766A (fr) | 1886-04-06 | Albert M. Todd | Procede de traitement des huiles volatiles pour en extraire le cristallin de la partie liquide | |
CA59350A (fr) | 1898-02-26 | 1898-03-19 | Thomas Henry Simmonds | Frein pour velocipedes, tricycles, etc. |
US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
US5837249A (en) | 1985-04-19 | 1998-11-17 | The Wistar Institute | Method for generating an immunogenic T cell response protective against a virus |
US5726288A (en) * | 1989-11-13 | 1998-03-10 | Massachusetts Institute Of Technology | Localization and characterization of the Wilms' tumor gene |
US5229115A (en) | 1990-07-26 | 1993-07-20 | Immunex Corporation | Adoptive immunotherapy with interleukin-7 |
EP0573608A1 (fr) | 1991-02-07 | 1993-12-15 | Molecumetics, Ltd. | Produits mimetiques de conformation restreinte de tours beta et bombements beta, et peptides les contenant |
CA2158281A1 (fr) | 1993-03-15 | 1994-09-29 | Jay A. Berzofsky | Cellules dentritiques revetues de peptide, agents immunogenes |
AU2392795A (en) | 1994-04-22 | 1995-11-16 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Isolation and characterization of a novel primate t-cell lymphotropic virus and the use of this virus or components thereof in diagnostics assays and vaccines |
US5622835A (en) | 1994-04-28 | 1997-04-22 | The Wistar Institute Of Anatomy & Biology | WT1 monoclonal antibodies |
US5643786A (en) | 1995-01-27 | 1997-07-01 | The United States Of America As Represented By The Department Of Health And Human Services | Method for isolating dendritic cells |
US6156316A (en) | 1995-05-08 | 2000-12-05 | Sloan-Kettering Institute For Cancer Research | Oncogene fusion protein peptide vaccines |
JPH11171896A (ja) | 1995-09-19 | 1999-06-29 | Kirin Brewery Co Ltd | 新規ペプチド化合物およびその医薬組成物 |
US5981217A (en) | 1995-12-11 | 1999-11-09 | Mayo Foundation For Medical Education And Research | DNA encoding TGF-β inducible early factor-1 (TIEF-1), a gene expressed by osteoblasts |
PT879282E (pt) | 1996-01-17 | 2003-11-28 | Imp College Innovations Ltd | Imunoterapia utilizando linfocitos t citotoxicos (ctl) |
US5853719A (en) | 1996-04-30 | 1998-12-29 | Duke University | Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA |
US6207375B1 (en) | 1996-12-11 | 2001-03-27 | Mayo Foundation For Medical Educational & Research | TGF-β inducible early factor-1 (TIEF-1) and a method to detect breast cancer |
ID27813A (id) | 1998-01-28 | 2001-04-26 | Corixa Corp | Senyawa-senyawa untuk terapi dan diagnosa kanker paru-paru dan metoda untuk penggunaannya |
BRPI9912663B8 (pt) | 1998-07-31 | 2021-07-06 | Int Inst Cancer Immunology Inc | vacina contra cáncer e polipeptìdeo. |
US20030072767A1 (en) | 1998-09-30 | 2003-04-17 | Alexander Gaiger | Compositions and methods for WT1 specific immunotherapy |
US7144581B2 (en) | 2000-10-09 | 2006-12-05 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7115272B1 (en) | 1998-09-30 | 2006-10-03 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US20030235557A1 (en) | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7655249B2 (en) | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7329410B1 (en) | 1998-09-30 | 2008-02-12 | Corixa Corporation | Compositions and method for WT1 specific immunotherapy |
US7063854B1 (en) * | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US20120301492A1 (en) | 1998-09-30 | 2012-11-29 | Corixa Corporation | Compositions and methods for wt1 specific immunotherapy |
GB9823897D0 (en) | 1998-11-02 | 1998-12-30 | Imp College Innovations Ltd | Immunotherapeutic methods and molecules |
EP1144444A3 (fr) | 1998-12-22 | 2002-01-02 | Genset | Adn complementaires codant pour des proteines secretees avec des peptides signaux |
AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
CA2367692A1 (fr) | 1999-03-15 | 2000-09-21 | Introgen Therapeutics, Inc. | Cellules dendritiques transduites avec un gene du soi de type sauvage suscitant des reponses immunitaires antitumorales puissantes |
US6593299B1 (en) * | 1999-04-21 | 2003-07-15 | University Of Florida Research Foundation, Inc. | Compositions and methods for controlling pests |
AU7859900A (en) | 1999-10-04 | 2001-05-10 | Corixa Corporation | Compositions and methods for wt1 specific immunotherapy |
US20030082194A1 (en) | 2000-02-22 | 2003-05-01 | Alexander Gaiger | Compositions and methods for diagnosis and therapy of malignant mesothelioma |
AU2001247220A1 (en) * | 2000-02-22 | 2001-09-03 | Corixa Corporation | Compositions and methods for diagnosis and therapy of malignant mesothelioma |
US20040002068A1 (en) | 2000-03-01 | 2004-01-01 | Corixa Corporation | Compositions and methods for the detection, diagnosis and therapy of hematological malignancies |
US6861234B1 (en) | 2000-04-28 | 2005-03-01 | Mannkind Corporation | Method of epitope discovery |
EP1209226A3 (fr) | 2000-11-07 | 2002-06-05 | GSF-Forschungszentrum für Umwelt und Gesundheit GmbH | Maturation de cellules dendritiques grâce à la protéine de choc thermique 70 (hsp70) recombinante |
TWI318630B (en) | 2001-03-22 | 2009-12-21 | Int Inst Cancer Immunology Inc | Wt1 modified peptide |
US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
DE60238958D1 (de) | 2001-06-29 | 2011-02-24 | Chugai Pharmaceutical Co Ltd | Krebsimpfstoff mit einem Krebs-Antigen auf Grundlage des Produkts aus dem Tumorunterdrückungsgen WT1 und einem kationischen Liposom |
US7553494B2 (en) | 2001-08-24 | 2009-06-30 | Corixa Corporation | WT1 fusion proteins |
US20050002951A1 (en) | 2001-09-28 | 2005-01-06 | Haruo Sugiyama | Novel method of inducing antigen-specific t cells |
EP1447091A4 (fr) | 2001-09-28 | 2008-02-13 | Institute Of Can International | Nouvelle methode pour induire des lymphocytes t specifiques d'antigenes |
US20030072761A1 (en) | 2001-10-16 | 2003-04-17 | Lebowitz Jonathan | Methods and compositions for targeting proteins across the blood brain barrier |
US20030175272A1 (en) | 2002-03-07 | 2003-09-18 | Medcell Biologics, Inc. | Re-activated T-cells for adoptive immunotherapy |
CN101113163B (zh) | 2002-06-12 | 2010-10-06 | 株式会社国际癌症免疫研究所 | Hla-a24限制性癌抗原肽 |
KR101173871B1 (ko) | 2003-02-06 | 2012-08-16 | 앤저 테라퓨틱스 인코퍼레이티드 | 변형된 독립생존 미생물, 백신 조성물 및 그것의 사용방법 |
US20050008618A1 (en) | 2003-02-27 | 2005-01-13 | Howard Kaufman | Composition for delivering an agent to a target cell and uses thereof |
WO2004111075A2 (fr) * | 2003-03-05 | 2004-12-23 | Dendreon Corporation | Compositions et procedes utilisant des polypeptides a cadre de lecture differents dans le traitement du cancer et de maladies infectieuses |
KR101431312B1 (ko) | 2003-06-27 | 2014-08-20 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | Wt1 백신 적응 환자의 선택 방법 |
US20050147621A1 (en) | 2003-10-10 | 2005-07-07 | Higgins Darren E. | Use of bacterial 5' untranslated regions for nucleic acid expression |
ES2378264T3 (es) | 2003-11-05 | 2012-04-10 | International Institute Of Cancer Immunology, Inc. | Péptido antigénico de unión a HLA-DR derivado de WT1 |
US7488718B2 (en) | 2003-12-01 | 2009-02-10 | Sloan Kettering Institue For Cancer Research | Synthetic HLA binding peptide analogues and uses thereof |
ATE426617T1 (de) | 2003-12-05 | 2009-04-15 | Multimmune Gmbh | Therapeutische und diagnostische anti-hsp 70- antikírper |
EP1550458A1 (fr) | 2003-12-23 | 2005-07-06 | Vectron Therapeutics AG | Adjuvants liposomals synergiques |
EP1720565A1 (fr) | 2004-03-04 | 2006-11-15 | Corixa Corporation | Formulations d'immunostimulants en microspheres et de polypeptide wt1 en co-encapsulation, et procedes correspondants |
US20050214268A1 (en) | 2004-03-25 | 2005-09-29 | Cavanagh William A Iii | Methods for treating tumors and cancerous tissues |
US20050221481A1 (en) | 2004-03-30 | 2005-10-06 | Istituto Superiore Di Sanita' | Amplification of T cells from human cord blood in serum-deprived culture stimulated with stem cell factor, interleukin-7 and interleukin-2 |
ATE462003T1 (de) | 2004-03-31 | 2010-04-15 | Int Inst Cancer Immunology Inc | Aus wt1 stammende krebsantigenpeptide |
US9629927B2 (en) | 2005-07-29 | 2017-04-25 | Sloan-Kettering Institute For Cancer Research | Single wall nanotube constructs and uses thereof |
EP1951281B1 (fr) | 2005-10-17 | 2015-04-15 | Sloan Kettering Institute For Cancer Research | Peptides de liaison wt1 hla de classe ii, compositions et methodes associees comprenant ces peptides |
KR101385805B1 (ko) * | 2005-11-30 | 2014-04-16 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 신규 펩티드 화합물 |
PL1988163T3 (pl) | 2006-02-22 | 2012-11-30 | Int Inst Cancer Immunology Inc | Ograniczony do hla-a*3303 peptyd wt1 i zawierająca go kompozycja farmaceutyczna |
WO2007119564A1 (fr) | 2006-03-29 | 2007-10-25 | International Institute Of Cancer Immunology, Inc. | ARNsi SPÉCIFIQUE DE L'ISOFORME WT1 17AA(-) ET SON UTILISATION |
EP3117836A1 (fr) | 2006-04-10 | 2017-01-18 | Sloan Kettering Institute For Cancer Research | Peptides wt-1 immunogènes et leurs utilisations |
WO2007120603A2 (fr) | 2006-04-10 | 2007-10-25 | Sloan Kettering Institute For Cancer Research | Peptides bcr-abl immunogènes et leurs méthodes d'utilisation |
CN101663323A (zh) | 2006-12-27 | 2010-03-03 | 埃默里大学 | 用于治疗传染病和肿瘤的组合物和方法 |
DK2341142T3 (en) | 2006-12-28 | 2014-12-08 | Int Inst Cancer Immunology Inc | HLA-A * 1101-restricted WT1 peptide or pharmaceutical composition comprising this |
WO2008096831A1 (fr) | 2007-02-07 | 2008-08-14 | The Research Foundation For Microbial Diseases Of Osaka University | Agent thérapeutique contre le cancer |
CN103103246B (zh) | 2007-02-27 | 2018-05-01 | 株式会社癌免疫研究所 | 活化辅助t细胞的方法以及用于该方法的组合物 |
KR20110091817A (ko) | 2007-05-24 | 2011-08-12 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 동결건조 항원 조성물 |
KR100995340B1 (ko) | 2007-11-19 | 2010-11-19 | 재단법인서울대학교산학협력재단 | 자연 살해 t 세포의 리간드와 항원을 적재한 단핵구 또는미분화 골수성 세포를 포함하는 백신 |
KR101592855B1 (ko) | 2007-12-05 | 2016-02-12 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 암 백신 조성물 |
KR100900837B1 (ko) | 2007-12-07 | 2009-06-04 | (주)두비엘 | 리포펩타이드와 폴리(i:c)를 아쥬반트로 포함하는 강력한백신 조성물 |
CA2724649A1 (fr) | 2008-05-19 | 2009-11-26 | Anza Therapeutics, Inc. | Compositions comportant un mutant prfa de listeria, et leurs procedes d'utilisation |
EP2337795A2 (fr) * | 2008-10-01 | 2011-06-29 | Dako Denmark A/S | Multimères de mhc dans des vaccins et la surveillance immunitaire contre le cancer |
AR076349A1 (es) | 2009-04-23 | 2011-06-01 | Int Inst Cancer Immunology Inc | Peptido auxiliar del antigeno del cancer |
WO2011059835A2 (fr) | 2009-11-11 | 2011-05-19 | Quest Diagnostics Investments Incorporated | Mutations wt1 pour le pronostic de troubles myéloprolifératifs |
US20110136141A1 (en) | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Peptide reagents and method for inhibiting autoantibody antigen binding |
US20110223187A1 (en) | 2010-02-15 | 2011-09-15 | Vafa Shahabi | Live listeria-based vaccines for central nervous system therapy |
MX353165B (es) | 2010-08-24 | 2017-12-20 | Univ Of Pittsburgh Of The Commonwealth System Of Higher Education Star | Vacunas contra el cancer cerebral basadas en peptido alfa 2 del receptor de interleucina 13. |
WO2012046730A1 (fr) | 2010-10-05 | 2012-04-12 | 国立大学法人大阪大学 | Procédé d'activation d'une cellule t auxiliaire |
AP2013007158A0 (en) | 2011-03-11 | 2013-10-31 | Gilead Calistoga Llc | Combination therapies for hematologic malignancies |
CA2839663A1 (fr) | 2011-06-28 | 2013-01-03 | International Institute Of Cancer Immunology, Inc. | Gene recepteur pour un lymphocyte t specifique d'un antigene cancereux peptidique |
EP2738253A4 (fr) | 2011-07-29 | 2015-04-22 | Riken | Cellule utilisable en immunothérapie qui contient un produit de recombinaison de type acide nucléique modifié codant pour un produit du gène de la tumeur de wilms ou pour un fragment de celui-ci, procédé de production de ladite cellule et dudit produit de recombinaison de type acide nucléique |
US9539299B2 (en) | 2011-10-27 | 2017-01-10 | International Institute Of Cancer Immunology, Inc. | Combination therapy with WT1 peptide vaccine and temozolomide |
CN104136609B (zh) | 2011-12-14 | 2016-12-07 | 国立大学法人高知大学 | 辅助性t细胞诱导多肽的修饰 |
CN104684577B (zh) | 2012-01-13 | 2018-05-08 | 纪念斯隆凯特林癌症中心 | 免疫原性wt-1肽及其使用方法 |
US9303079B2 (en) | 2012-04-02 | 2016-04-05 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9751928B2 (en) | 2012-05-03 | 2017-09-05 | Fred Hutchinson Cancer Research Center | Enhanced affinity T cell receptors and methods for making the same |
JP6163486B2 (ja) | 2012-07-02 | 2017-07-12 | 大日本住友製薬株式会社 | 癌抗原ペプチド経皮剤 |
EP2911683B1 (fr) | 2012-10-23 | 2019-09-25 | Ubivac, LLC | Composition enrichie en autophagosome allogénique pour le traitement de maladies |
EP2933261B1 (fr) | 2012-12-17 | 2020-06-10 | Otsuka Pharmaceutical Co., Ltd. | Procédé pour activer des lymphocytes t auxiliaires |
WO2014103310A1 (fr) | 2012-12-26 | 2014-07-03 | バイオコモ株式会社 | Vaccin préparé à l'aide d'un vecteur du virus parainfluenza humain de type 2 |
PT2945647T (pt) | 2013-01-15 | 2020-11-26 | Memorial Sloan Kettering Cancer Center | Péptidos imunogénicos wt-1 e métodos de uso dos mesmos |
KR20140100419A (ko) | 2013-02-05 | 2014-08-14 | 닛토덴코 가부시키가이샤 | 경피 투여용 wt1 펩티드 암 백신 조성물 |
CA2840988A1 (fr) | 2013-02-05 | 2014-08-05 | Nitto Denko Corporation | Composition de vaccin contre le cancer avec peptide wt1 pour administration muqueuse |
RU2685933C2 (ru) | 2013-02-05 | 2019-04-23 | Нитто Денко Корпорейшн | Композиция противораковой вакцины, содержащая пептид wt1, для трансдермального введения |
JP6512569B2 (ja) | 2013-02-05 | 2019-05-15 | 日東電工株式会社 | 経皮投与用wt1ペプチド癌ワクチンテープ剤 |
EP2956544B1 (fr) | 2013-02-14 | 2017-11-01 | Immunocellular Therapeutics Ltd. | Vaccins contre le cancer et méthodes de vaccination |
ES2694328T3 (es) | 2013-03-12 | 2018-12-19 | Sumitomo Dainippon Pharma Co., Ltd. | Composición acuosa líquida |
US11419925B2 (en) | 2013-03-15 | 2022-08-23 | The Trustees Of The University Of Pennsylvania | Cancer vaccines and methods of treatment using the same |
MX364459B (es) | 2013-03-29 | 2019-04-26 | Sumitomo Dainippon Pharma Co Ltd | Vacuna de conjugado de péptido-antígeno de wt1. |
MX364922B (es) | 2013-04-25 | 2019-05-14 | Vaximm Ag | Vacuna de adn que dirige wt-1 novedosa para inmunoterapia contra cáncer. |
KR20160007579A (ko) | 2013-05-13 | 2016-01-20 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 면역요법의 임상 효과의 예측법 |
US10898555B2 (en) | 2013-07-02 | 2021-01-26 | Japanese Foundation For Cancer Research | Cellular immunity inducing vaccine |
PL3071593T3 (pl) | 2013-11-22 | 2019-11-29 | Univ Illinois | Konstruowane ludzkie receptory komórek T o wysokim powinowactwie |
RU2016129044A (ru) | 2013-12-18 | 2018-01-23 | Факсимм Гмбх | Новая вакцина днк, нацеленная на мезотелин, для иммунотерапии рака |
CA2935375C (fr) | 2014-01-06 | 2023-08-08 | The Trustees Of The University Of Pennsylvania | Anticorps pd1 et pdl1 et combinaisons de vaccin et utilisation de celles-ci pour l'immunotherapie |
EP3104878B1 (fr) | 2014-02-14 | 2019-05-22 | Immune Design Corp. | Immunothérapie du cancer par combinaison de stimulation immunitaire locale et systémique |
WO2015129790A1 (fr) | 2014-02-26 | 2015-09-03 | 株式会社バイオイミュランス | Polypeptide antigénique wt1, et agent antitumoral contenant ledit polypeptide |
US10023841B2 (en) | 2014-05-23 | 2018-07-17 | Baylor Research Institute | Methods and compositions for treating breast cancer with dendritic cell vaccines |
US10525096B2 (en) | 2014-12-11 | 2020-01-07 | International Institute Of Cancer Immunology, Inc. | Immunotherapy for angiogenic disease |
US10695385B2 (en) | 2015-06-25 | 2020-06-30 | National University Corporation Kobe University | Oral cancer vaccine |
US20190054112A1 (en) | 2015-09-18 | 2019-02-21 | Moderna Therapeutics, Inc. | Polynucleotide formulations for use in the treatment of renal diseases |
-
2013
- 2013-01-14 CN CN201380014022.7A patent/CN104684577B/zh active Active
- 2013-01-14 CN CN201810342393.2A patent/CN108676069A/zh active Pending
- 2013-01-14 US US14/372,174 patent/US20150104413A1/en not_active Abandoned
- 2013-01-14 WO PCT/US2013/021448 patent/WO2013106834A2/fr active Application Filing
- 2013-01-14 EP EP18215878.2A patent/EP3520810A3/fr active Pending
- 2013-01-14 EP EP13736176.2A patent/EP2802347B1/fr active Active
- 2013-01-14 AU AU2013207669A patent/AU2013207669C1/en active Active
- 2013-01-14 JP JP2014552368A patent/JP6282598B2/ja active Active
- 2013-01-14 CA CA2861206A patent/CA2861206C/fr active Active
-
2015
- 2015-05-18 HK HK15104710.4A patent/HK1204261A1/xx unknown
-
2017
- 2017-05-30 US US15/608,964 patent/US10100087B2/en active Active
-
2018
- 2018-01-24 JP JP2018009786A patent/JP6995645B2/ja active Active
- 2018-02-20 AU AU2018201210A patent/AU2018201210B2/en active Active
- 2018-09-07 US US16/125,213 patent/US10815274B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2802347A2 (fr) | 2014-11-19 |
AU2018201210A1 (en) | 2018-03-08 |
JP2015512866A (ja) | 2015-04-30 |
WO2013106834A3 (fr) | 2015-01-22 |
US10815274B2 (en) | 2020-10-27 |
CN104684577A (zh) | 2015-06-03 |
EP2802347A4 (fr) | 2016-06-01 |
WO2013106834A2 (fr) | 2013-07-18 |
AU2018201210B2 (en) | 2020-04-09 |
AU2013207669A1 (en) | 2014-08-07 |
EP2802347B1 (fr) | 2019-01-09 |
CA2861206A1 (fr) | 2013-07-18 |
US20190092813A1 (en) | 2019-03-28 |
JP6995645B2 (ja) | 2022-01-14 |
EP3520810A2 (fr) | 2019-08-07 |
US10100087B2 (en) | 2018-10-16 |
EP3520810A3 (fr) | 2019-11-06 |
CN104684577B (zh) | 2018-05-08 |
JP2018104438A (ja) | 2018-07-05 |
CN108676069A (zh) | 2018-10-19 |
CA2861206C (fr) | 2021-07-06 |
AU2013207669B2 (en) | 2017-11-23 |
AU2013207669C1 (en) | 2018-05-31 |
US20170334951A1 (en) | 2017-11-23 |
JP6282598B2 (ja) | 2018-02-21 |
AU2013207669B9 (en) | 2017-12-14 |
US20150104413A1 (en) | 2015-04-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1204261A1 (en) | Immunogenic wt-1 peptides and methods of use thereof wt-1 | |
PT2945647T (pt) | Péptidos imunogénicos wt-1 e métodos de uso dos mesmos | |
EP2912178A4 (fr) | Super-activateurs et procédés d'utilisation de ceux-ci | |
HK1208439A1 (en) | 5-azaindazole compounds and methods of use 5- | |
HK1199892A1 (en) | Modified mini-hepcidin peptides and methods of using thereof | |
ZA201501858B (en) | Anti-mcam antibodies and associated methods of use | |
PT2925782T (pt) | Anticorpos anti-cd47 e métodos de utilização destes | |
ZA201405858B (en) | Recombinant microorganisms and methods of use thereof | |
EP2895083A4 (fr) | Ligateur et procédé d'utilisation | |
EP2870170A4 (fr) | Nouveaux peptides et leur utilisation | |
HK1206037A1 (en) | Human antibodies to gfr3 and methods of use thereof gfr3 | |
IL238227A0 (en) | Antibodies against c16orf54 and uses thereof | |
HK1197187A1 (en) | Anti-lrp5 antibodies and methods of use lrp5 | |
EP2782589A4 (fr) | Peptides antimicrobiens et procédés d'utilisation de ces derniers | |
HK1225645A1 (zh) | Pcv2b趨異株疫苗組合物以及使用方法 | |
EP2863858A4 (fr) | Systèmes de soutien pour patient et leurs procédés d'utilisation | |
EP2806811A4 (fr) | Construction vertébrale | |
HK1203161A1 (en) | Peptides and methods of using same | |
EP2938632A4 (fr) | Anticorps anti-granulysine et leurs procédés d'utilisation | |
EP2897639A4 (fr) | Compositions de vaccins perfectionnées et méthodes d'utilisation | |
EP2852397A4 (fr) | Variants d'huwentoxine iv et procédés d'utilisation | |
HK1209432A1 (en) | Anti-jagged antibodies and methods of use | |
SG11201504805PA (en) | Porcine parvovirus 5a, methods of use and vaccine | |
EP2897680A4 (fr) | Dispositifs de gonflage et leurs procédés d'utilisation | |
EP2925341A4 (fr) | Composés peptidiques et leurs procédés de production et d'utilisation |