HK1202921A1 - Method for the detection of a binding partner of a multispecific binder - Google Patents

Method for the detection of a binding partner of a multispecific binder

Info

Publication number
HK1202921A1
HK1202921A1 HK15103324.4A HK15103324A HK1202921A1 HK 1202921 A1 HK1202921 A1 HK 1202921A1 HK 15103324 A HK15103324 A HK 15103324A HK 1202921 A1 HK1202921 A1 HK 1202921A1
Authority
HK
Hong Kong
Prior art keywords
detection
binding partner
multispecific binder
multispecific
binder
Prior art date
Application number
HK15103324.4A
Other languages
English (en)
Chinese (zh)
Inventor
Kay-Gunnar Stubenrauch
Uwe Wessels
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1202921A1 publication Critical patent/HK1202921A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
HK15103324.4A 2012-02-01 2015-04-01 Method for the detection of a binding partner of a multispecific binder HK1202921A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12153457 2012-02-01
EP12182505 2012-08-31
PCT/EP2013/051604 WO2013113663A1 (en) 2012-02-01 2013-01-29 Method for the detection of a binding partner of a multispecific binder

Publications (1)

Publication Number Publication Date
HK1202921A1 true HK1202921A1 (en) 2015-10-09

Family

ID=47624068

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15103324.4A HK1202921A1 (en) 2012-02-01 2015-04-01 Method for the detection of a binding partner of a multispecific binder

Country Status (11)

Country Link
US (3) US9945869B2 (de)
EP (1) EP2810074B1 (de)
JP (3) JP2015507193A (de)
KR (1) KR20140128314A (de)
CN (2) CN104105966B (de)
BR (1) BR112014017630A8 (de)
CA (1) CA2859268A1 (de)
HK (1) HK1202921A1 (de)
MX (1) MX349661B (de)
RU (1) RU2620563C2 (de)
WO (1) WO2013113663A1 (de)

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RU2636822C2 (ru) 2012-07-13 2017-11-28 Ф.Хоффманн-Ля Рош Аг Способ обнаружения мультиспецифического связывающего агента
EP3066469B1 (de) 2013-11-05 2017-10-11 Roche Diagnostics GmbH Verfahren zur bestimmung der gesamtmenge und/oder konzentration eines analyten bei vorhandensein eines bindemoleküls sowie kits, zusammensetzungen und verwendungen
CN104109197B (zh) * 2013-11-13 2017-05-10 叶森 一种双识别抗体片段的制备方法及其应用
UA124925C2 (en) 2015-10-02 2021-12-15 Hoffmann La Roche Bispecific antibodies specific for pd1 and tim3
JP6734919B2 (ja) * 2015-10-02 2020-08-05 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 同時結合を測定するための細胞ベースのｆｒｅｔアッセイ法
PE20191494A1 (es) 2017-04-03 2019-10-21 Hoffmann La Roche Inmunoconjugados de un anticuerpo anti-pd-1 con un il-2 mutante o con il-15
TWI690538B (zh) 2017-04-05 2020-04-11 瑞士商赫孚孟拉羅股份公司 特異性結合至pd1至lag3的雙特異性抗體
US20210231654A1 (en) 2018-06-04 2021-07-29 Chugai Seiyaku Kabushiki Kaisha Method for detecting complex
EP3969907A1 (de) 2019-05-13 2022-03-23 F. Hoffmann-La Roche AG Interferenzunterdrücktes pharmakokinetisches immunoassay
WO2022065052A1 (ja) * 2020-09-24 2022-03-31 株式会社Ｊｖｃケンウッド 捕捉用抗体、固相担体、検出用抗体、固相担体粒子、並びに検出対象物質の測定キット及び測定方法
CN117805397A (zh) * 2024-02-29 2024-04-02 军科正源（北京）药物研究有限责任公司 检测游离vegf的方法

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JP6203747B2 (ja) * 2011-12-19 2017-09-27 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 多特異性結合体の遊離結合パートナーの検出方法
CA2859268A1 (en) 2012-02-01 2013-08-08 F. Hoffmann-La Roche Ag Method for the detection of a binding partner of a multispecific binder
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Also Published As

Publication number Publication date
CA2859268A1 (en) 2013-08-08
EP2810074A1 (de) 2014-12-10
JP2017223710A (ja) 2017-12-21
US20180328942A1 (en) 2018-11-15
WO2013113663A1 (en) 2013-08-08
US20140342382A1 (en) 2014-11-20
BR112014017630A2 (de) 2017-06-20
JP2019113564A (ja) 2019-07-11
JP2015507193A (ja) 2015-03-05
RU2620563C2 (ru) 2017-05-26
BR112014017630A8 (pt) 2017-07-11
CN106443016A (zh) 2017-02-22
MX349661B (es) 2017-08-08
MX2014008762A (es) 2014-08-27
JP6502441B2 (ja) 2019-04-17
EP2810074B1 (de) 2017-08-23
US20210055304A1 (en) 2021-02-25
KR20140128314A (ko) 2014-11-05
JP6678792B2 (ja) 2020-04-08
US9945869B2 (en) 2018-04-17
RU2014133701A (ru) 2016-03-27
CN104105966B (zh) 2016-10-26
CN104105966A (zh) 2014-10-15
CN106443016B (zh) 2019-08-13
US10761097B2 (en) 2020-09-01

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