HK1202066A1 - Suspensions of cyclosporin a form 2 2 a - Google Patents
Suspensions of cyclosporin a form 2 2 aInfo
- Publication number
- HK1202066A1 HK1202066A1 HK15102628.9A HK15102628A HK1202066A1 HK 1202066 A1 HK1202066 A1 HK 1202066A1 HK 15102628 A HK15102628 A HK 15102628A HK 1202066 A1 HK1202066 A1 HK 1202066A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cyclosporin
- suspensions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161559866P | 2011-11-15 | 2011-11-15 | |
| PCT/US2012/065011 WO2013074625A1 (en) | 2011-11-15 | 2012-11-14 | Suspensions of cyclosporin a form 2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1202066A1 true HK1202066A1 (en) | 2015-09-18 |
Family
ID=47278531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15102628.9A HK1202066A1 (en) | 2011-11-15 | 2015-03-16 | Suspensions of cyclosporin a form 2 2 a |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US8796222B2 (ko) |
| EP (2) | EP3701939A1 (ko) |
| JP (3) | JP6363506B2 (ko) |
| KR (1) | KR102015152B1 (ko) |
| CN (1) | CN104080442B (ko) |
| AU (4) | AU2012339632A1 (ko) |
| BR (1) | BR112014011770B1 (ko) |
| CA (1) | CA2856057C (ko) |
| DK (1) | DK2779994T3 (ko) |
| ES (1) | ES2791751T3 (ko) |
| HK (1) | HK1202066A1 (ko) |
| RU (1) | RU2641963C2 (ko) |
| WO (1) | WO2013074625A1 (ko) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104080442B (zh) * | 2011-11-15 | 2018-01-05 | 阿勒根公司 | 环孢菌素a形式2的悬浮液 |
| EP3263587A1 (en) | 2012-06-01 | 2018-01-03 | Allergan, Inc. | Cyclosporin a analogs |
| US20150352176A1 (en) * | 2014-06-06 | 2015-12-10 | Newport Research, Inc. | Oil-free and fat-free aqueous suspensions of cyclosporin |
| US10780048B2 (en) * | 2014-07-18 | 2020-09-22 | Allergan, Inc. | Suspension compositions of cyclosporin A for subconjunctival and periocular injection |
| IL282504B (en) * | 2014-09-17 | 2022-08-01 | Panoptica Inc | Ocular formulations for drug administration and protection of the front part of the eye |
| CN104511012B (zh) * | 2015-01-07 | 2017-01-18 | 鲁南厚普制药有限公司 | 一种环孢素口服溶液 |
| WO2016112321A1 (en) | 2015-01-08 | 2016-07-14 | Allergan, Inc. | Cyclosporin derivatives wherein the mebmt sidechain has been cyclized |
| US11583496B2 (en) * | 2016-10-12 | 2023-02-21 | PS Therapy Inc. | Drug vehicle compositions and methods of use thereof |
| CN113559059B (zh) * | 2021-07-21 | 2023-04-28 | 上海应用技术大学 | 一种阳离子纳米混悬液及其制备方法和应用 |
| KR102640323B1 (ko) | 2021-11-30 | 2024-02-27 | 대우제약 주식회사 | 사이클로스포린의 안정한 나노 현탁액 |
| WO2024019118A1 (ja) * | 2022-07-20 | 2024-01-25 | 旭化成株式会社 | ヒアルロン酸誘導体医薬品組成物及び医薬品組成物 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE109970T1 (de) * | 1987-09-03 | 1994-09-15 | Univ Georgia Res Found | Cyclosporin-augenmittel. |
| HU203564B (en) * | 1987-12-21 | 1991-08-28 | Sandoz Ag | Process for producing new orthorombos cyclosporin without solvatation |
| US5474979A (en) | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
| PT789580E (pt) * | 1994-11-03 | 2002-09-30 | Novartis Ag | Formulacoes de ciclosporina para administracao oral com composicao simples e alta biodisponibilidade e processo para a sua producao |
| DE19819273A1 (de) * | 1998-04-30 | 1999-11-11 | Pharmatec International S Giul | Pharmazeutische Ciclosporin-Formulierung mit verbesserten biopharmazeutischen Eigenschaften, erhöhter physikalischer Qualität und Stabilität sowie Verfahren zur Herstellung |
| US6254860B1 (en) | 1999-04-13 | 2001-07-03 | Allergan Sales, Inc. | Ocular treatment using cyclosporin-A derivatives |
| US7732404B2 (en) * | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| WO2002087563A2 (en) * | 2001-05-01 | 2002-11-07 | Angiotech Pharmaceuticals Inc. | Compositions comprising an anti-microtubule agent and a polypeptide or a polysaccharide and the use thereof for the preparation of a medicament for the treatment of inflammatory conditions |
| GB2391472B (en) * | 2002-08-02 | 2004-12-08 | Satishchandra Punambhai Patel | Pharmaceutical compositions |
| MXPA05010373A (es) | 2003-04-01 | 2005-12-05 | Applied Research Systems | Inhibidores de fosfodiesterasas en infertilidad. |
| JP2007518804A (ja) | 2004-01-20 | 2007-07-12 | アラーガン、インコーポレイテッド | トリアムシノロンアセトニドおよびヒアルロン酸を好ましく含有する眼局所治療用組成物 |
| ATE412400T1 (de) * | 2004-11-09 | 2008-11-15 | Novagali Pharma Sa | Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential |
| US7288520B2 (en) * | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
| US10137083B2 (en) | 2006-03-07 | 2018-11-27 | SGN Nanopharma Inc | Ophthalmic preparations |
| EP2001439A2 (en) | 2006-03-07 | 2008-12-17 | Novavax, Inc. | Nanoemulsions of poorly soluble pharmaceutical active ingredients and methods of making the same |
| CN101484138A (zh) * | 2006-03-07 | 2009-07-15 | 诺瓦瓦克斯有限公司 | 难溶性药用活性成分的纳米乳液和制备该乳液的方法 |
| EP2234629A4 (en) * | 2008-01-04 | 2011-05-25 | Alcon Pharmaceuticals Ltd | STABLE AQUEOUS CYCLOSPORIN COMPOSITIONS |
| US20100303915A1 (en) * | 2009-06-02 | 2010-12-02 | Abbott Medical Optics Inc. | Therapeutic opthalmic emulsions |
| WO2011049958A2 (en) * | 2009-10-21 | 2011-04-28 | Otonomy, Inc. | Modulation of gel temperature of poloxamer-containing formulations |
| US8772245B2 (en) | 2011-05-27 | 2014-07-08 | Allergan, Inc. | Crystalline form of cyclosporine A, methods of preparation, and methods for use thereof |
| CN108175742B (zh) * | 2011-11-15 | 2021-10-22 | 阿勒根公司 | 环孢菌素形式2的持续作用型制剂 |
| CN104080442B (zh) * | 2011-11-15 | 2018-01-05 | 阿勒根公司 | 环孢菌素a形式2的悬浮液 |
-
2012
- 2012-11-14 CN CN201280066573.3A patent/CN104080442B/zh active Active
- 2012-11-14 CA CA2856057A patent/CA2856057C/en active Active
- 2012-11-14 DK DK12794830.5T patent/DK2779994T3/da active
- 2012-11-14 EP EP20156348.3A patent/EP3701939A1/en not_active Withdrawn
- 2012-11-14 WO PCT/US2012/065011 patent/WO2013074625A1/en active Application Filing
- 2012-11-14 AU AU2012339632A patent/AU2012339632A1/en not_active Abandoned
- 2012-11-14 RU RU2014123470A patent/RU2641963C2/ru active
- 2012-11-14 KR KR1020147016157A patent/KR102015152B1/ko active IP Right Grant
- 2012-11-14 US US13/677,014 patent/US8796222B2/en active Active
- 2012-11-14 EP EP12794830.5A patent/EP2779994B1/en active Active
- 2012-11-14 BR BR112014011770-5A patent/BR112014011770B1/pt active IP Right Grant
- 2012-11-14 ES ES12794830T patent/ES2791751T3/es active Active
- 2012-11-14 JP JP2014542400A patent/JP6363506B2/ja active Active
-
2014
- 2014-07-07 US US14/325,167 patent/US9238002B2/en active Active
-
2015
- 2015-03-16 HK HK15102628.9A patent/HK1202066A1/xx unknown
-
2016
- 2016-01-14 US US14/995,868 patent/US10206971B2/en active Active
-
2017
- 2017-09-27 AU AU2017235927A patent/AU2017235927A1/en not_active Abandoned
-
2018
- 2018-06-28 JP JP2018122767A patent/JP2018162296A/ja active Pending
-
2019
- 2019-02-15 US US16/277,016 patent/US20190343917A1/en not_active Abandoned
- 2019-04-30 AU AU2019203051A patent/AU2019203051A1/en not_active Abandoned
- 2019-11-20 JP JP2019209351A patent/JP2020040968A/ja active Pending
-
2020
- 2020-11-18 AU AU2020270500A patent/AU2020270500B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10206971B2 (en) | 2019-02-19 |
| RU2641963C2 (ru) | 2018-01-23 |
| CN104080442B (zh) | 2018-01-05 |
| US9238002B2 (en) | 2016-01-19 |
| EP2779994A1 (en) | 2014-09-24 |
| DK2779994T3 (da) | 2020-05-18 |
| ES2791751T3 (es) | 2020-11-05 |
| CA2856057C (en) | 2017-01-03 |
| BR112014011770A2 (pt) | 2017-05-09 |
| EP3701939A1 (en) | 2020-09-02 |
| WO2013074625A1 (en) | 2013-05-23 |
| CA2856057A1 (en) | 2013-05-23 |
| KR20140107254A (ko) | 2014-09-04 |
| AU2012339632A1 (en) | 2014-06-05 |
| AU2020270500B2 (en) | 2022-11-24 |
| JP6363506B2 (ja) | 2018-07-25 |
| JP2018162296A (ja) | 2018-10-18 |
| JP2020040968A (ja) | 2020-03-19 |
| EP2779994B1 (en) | 2020-02-19 |
| US8796222B2 (en) | 2014-08-05 |
| JP2014533302A (ja) | 2014-12-11 |
| US20140322335A1 (en) | 2014-10-30 |
| AU2017235927A1 (en) | 2017-10-19 |
| AU2020270500A1 (en) | 2020-12-17 |
| US20130122059A1 (en) | 2013-05-16 |
| US20160129074A1 (en) | 2016-05-12 |
| BR112014011770B1 (pt) | 2022-11-08 |
| KR102015152B1 (ko) | 2019-08-27 |
| US20190343917A1 (en) | 2019-11-14 |
| RU2014123470A (ru) | 2015-12-27 |
| CN104080442A (zh) | 2014-10-01 |
| AU2019203051A1 (en) | 2019-05-23 |
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