HK1199469A1 - 幹細胞的產生和保持 - Google Patents
幹細胞的產生和保持Info
- Publication number
- HK1199469A1 HK1199469A1 HK14112897.3A HK14112897A HK1199469A1 HK 1199469 A1 HK1199469 A1 HK 1199469A1 HK 14112897 A HK14112897 A HK 14112897A HK 1199469 A1 HK1199469 A1 HK 1199469A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- maintenance
- generation
- stem cells
- stem
- cells
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
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- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2306—Interleukin-6 (IL-6)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Transplantation (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13840708P | 2008-12-17 | 2008-12-17 |
Publications (1)
Publication Number | Publication Date |
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HK1199469A1 true HK1199469A1 (zh) | 2015-07-03 |
Family
ID=42310146
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK14112897.3A HK1199469A1 (zh) | 2008-12-17 | 2012-03-28 | 幹細胞的產生和保持 |
Country Status (14)
Country | Link |
---|---|
US (4) | US8906677B2 (zh) |
EP (2) | EP3312269A1 (zh) |
JP (5) | JP6093110B2 (zh) |
KR (2) | KR101909847B1 (zh) |
CN (2) | CN104130976A (zh) |
AU (3) | AU2009333259B2 (zh) |
BR (1) | BRPI0922572A2 (zh) |
CA (1) | CA2747398C (zh) |
ES (1) | ES2645869T3 (zh) |
HK (1) | HK1199469A1 (zh) |
IL (1) | IL213582A0 (zh) |
NO (1) | NO2373784T3 (zh) |
SG (1) | SG172160A1 (zh) |
WO (1) | WO2010077955A1 (zh) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2009225665B9 (en) | 2008-03-17 | 2015-01-15 | The Scripps Research Institute | Combined chemical and genetic approaches for generation of induced pluripotent stem cells |
EP3312269A1 (en) | 2008-12-17 | 2018-04-25 | The Scripps Research Institute | Generation and maintenance of stem cells |
US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
EP3441458B9 (en) | 2009-02-03 | 2023-08-23 | Koninklijke Nederlandse Akademie van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising said stem cells |
CA2762369C (en) * | 2009-05-18 | 2021-12-28 | Joseph Collard | Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor |
EP3235901B1 (en) | 2009-10-16 | 2022-12-21 | The Scripps Research Institute | Induction of pluripotent cells |
KR101775926B1 (ko) | 2009-11-04 | 2017-09-07 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 화학 물질을 이용한 에피솜 재프로그래밍 |
JP5909482B2 (ja) | 2010-03-31 | 2016-04-26 | ザ スクリプス リサーチ インスティテュート | 細胞の再プログラム |
EP2580320B1 (en) | 2010-06-14 | 2018-08-01 | The Scripps Research Institute | Reprogramming of cells to a new fate |
US20130130387A1 (en) * | 2010-07-27 | 2013-05-23 | Technion Research & Development Foundation Limited | Method for generating induced pluripotent stem cells from keratinocytes derived from plucked hair follicles |
US9144585B2 (en) | 2010-07-27 | 2015-09-29 | Technion Research & Development Foundation Limited | Isolated mesenchymal progenitor cells and extracellular matrix produced thereby |
WO2012036299A1 (en) | 2010-09-14 | 2012-03-22 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
US20130267029A1 (en) | 2010-10-01 | 2013-10-10 | Fundacion Centro Nacional de Ivestigaciones Oncologicas, Carlos | Manipulation of stem cell function by p53 isoforms |
AU2011349446C1 (en) | 2010-12-22 | 2016-01-21 | Fate Therapauetics, Inc. | Cell culture platform for single cell sorting and enhanced reprogramming of iPSCs |
US10428309B2 (en) | 2011-12-01 | 2019-10-01 | New York Stem Cell Foundation, Inc. | Systems and methods for producing stem cells and differentiated cells |
BR112014013152B1 (pt) | 2011-12-01 | 2021-08-31 | New York Stem Cell Foundation, Inc | Sistema automatizado para geração de células-tronco pluripotentes induzidas (ipscs) |
EP2872619B1 (en) * | 2012-07-11 | 2018-02-14 | Imstem Biotechnology Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
ES2904803T3 (es) * | 2013-02-20 | 2022-04-06 | Regeneron Pharma | Modificación genética de ratas |
US20150037883A1 (en) * | 2013-03-03 | 2015-02-05 | Royan Institute | Method for derivation and long-term establishment of ground state pluripotent embryonic stem cells |
PT3456831T (pt) | 2013-04-16 | 2021-09-10 | Regeneron Pharma | Modificação alvejada do genoma de rato |
JP2016521971A (ja) * | 2013-04-23 | 2016-07-28 | イェダ リサーチ アンド ディベロップメント カンパニー リミテッド | 単離ナイーブ型多能性幹細胞およびそれを発生させる方法関連出願本出願は、米国特許法119条第(e)項に基づき、2014年1月29日出願の米国特許仮出願第61/932,935号、2013年9月17日出願の米国特許仮出願第61/878,769号、および2013年4月23日出願の米国特許仮出願第61/814,920号の優先権を主張する。また、本出願は、同時に提出された同出願人による同時係属出願である、YaqubHANNA、NoaNOVERSHTERN、およびYoachRAISによる米国特許出願(発明の名称「単離ナイーブ型多能性幹細胞およびそれを発生させる方法(ISOLATEDNAIVEPLURIPOTENTSTEMCELLSANDMETHODSOFGENERATINGSAME)」)(代理人事件記録簿第58870号)にも関する。上記出願の内容はその全体を参考として本明細書に組み込む。 |
NZ715302A (en) | 2013-06-14 | 2021-12-24 | Univ Queensland | Renal progenitor cells |
KR101655383B1 (ko) | 2013-07-27 | 2016-09-08 | 고려대학교 산학협력단 | 소분자 화합물을 포함하는 만능성 줄기세포의 염색체 안정성 유지용 조성물 |
US9512406B2 (en) | 2013-12-20 | 2016-12-06 | The J. David Gladstone Institute, a testamentary trust established under the Will of J. David Gladstone | Generating hepatocytes |
EP3805369A1 (en) | 2014-03-04 | 2021-04-14 | Fate Therapeutics, Inc. | Improved reprogramming methods and cell culture platforms |
US11203739B2 (en) | 2014-04-07 | 2021-12-21 | Memorial Sloan-Kettering Cancer Center | Modulating cell proliferation and pluripotency |
EP3194572B1 (en) * | 2014-07-30 | 2023-10-25 | Yeda Research and Development Co. Ltd. | Media for culturing pluripotent stem cells |
WO2016027099A2 (en) | 2014-08-22 | 2016-02-25 | Cambridge Enterprise Limited | Resetting pluripotent stem cells |
CN105441384B (zh) * | 2014-09-26 | 2021-01-05 | 北京大学 | 一种制备动物和人类原始多潜能干细胞的方法,试剂盒及用途 |
EP3770252A1 (en) | 2015-01-26 | 2021-01-27 | Fate Therapeutics, Inc. | Cells with increased immuno-regulatory properties and methods for their use and manufacture |
WO2016210292A1 (en) * | 2015-06-25 | 2016-12-29 | Children's Medical Center Corporation | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance |
WO2017015320A1 (en) | 2015-07-21 | 2017-01-26 | Children's Medical Center Corporation | Pd-l1 expressing hematopoietic stem cells and uses |
AU2016338680B2 (en) | 2015-10-16 | 2022-11-17 | Fate Therapeutics, Inc. | Platform for the induction and maintenance of ground state pluripotency |
EP3365428A4 (en) * | 2015-10-21 | 2019-03-20 | Indiana University Research&Technology Corporation | METHODS FOR PRODUCING SENSORY EPITHELIAL CELLS AND SENSORY NEURONS OF THE INTERNAL EAR IN MAN |
JP6937036B2 (ja) | 2016-03-08 | 2021-09-22 | 公立大学法人名古屋市立大学 | 人工多能性幹細胞の腸管上皮細胞への分化誘導 |
AU2017235461B2 (en) | 2016-03-15 | 2023-02-23 | Children's Medical Center Corporation | Methods and compositions relating to hematopoietic stem cell expansion |
EP3455346A1 (en) | 2016-05-12 | 2019-03-20 | Erasmus University Medical Center Rotterdam | A method for culturing myogenic cells, cultures obtained therefrom, screening methods, and cell culture medium |
DK3519558T3 (da) | 2016-09-28 | 2023-11-13 | Organovo Inc | Anvendelse af modificeret nyrevæv i assays |
CN109890956A (zh) * | 2016-10-28 | 2019-06-14 | 国立研究开发法人国立癌研究中心 | 人肝前体细胞的制备方法 |
JP2018091790A (ja) * | 2016-12-06 | 2018-06-14 | 東ソー株式会社 | 細胞の染色方法 |
WO2018208836A1 (en) * | 2017-05-08 | 2018-11-15 | Regents Of The University Of Minnesota | Acceleration of stem cell differentiation |
NL2019517B1 (en) | 2017-09-08 | 2019-03-19 | Univ Erasmus Med Ct Rotterdam | New therapy for Pompe disease |
WO2019060708A1 (en) | 2017-09-22 | 2019-03-28 | The Children's Medical Center Corporation | TREATMENT OF TYPE 1 DIABETES AND AUTOIMMUNE DISEASES OR DISORDERS |
TW201940693A (zh) | 2017-11-30 | 2019-10-16 | 國立大學法人京都大學 | 細胞之培養方法 |
JPWO2019151386A1 (ja) * | 2018-01-31 | 2021-01-07 | 富士フイルム株式会社 | 細胞の製造方法 |
CN111684058B (zh) | 2018-02-09 | 2023-07-28 | 公立大学法人名古屋市立大学 | 从多能干细胞向肠上皮细胞的分化诱导方法 |
US11901045B2 (en) | 2019-01-15 | 2024-02-13 | International Business Machines Corporation | Machine learning framework for finding materials with desired properties |
KR102224273B1 (ko) * | 2019-10-10 | 2021-03-08 | 고려대학교 산학협력단 | 줄기세포 유래 성숙 심근세포 및 이를 이용한 심혈관 질환 모델 |
EP3922431A1 (en) | 2020-06-08 | 2021-12-15 | Erasmus University Medical Center Rotterdam | Method of manufacturing microdevices for lab-on-chip applications |
CN112063656A (zh) * | 2020-08-28 | 2020-12-11 | 中国科学院广州生物医药与健康研究院 | Map2k3或Map2k6在提高诱导成体细胞生成多能性干细胞效率中的用途 |
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