HK1199099A1 - 用於治療和診斷癌症的方法和組合物 - Google Patents

用於治療和診斷癌症的方法和組合物

Info

Publication number
HK1199099A1
HK1199099A1 HK14112558.3A HK14112558A HK1199099A1 HK 1199099 A1 HK1199099 A1 HK 1199099A1 HK 14112558 A HK14112558 A HK 14112558A HK 1199099 A1 HK1199099 A1 HK 1199099A1
Authority
HK
Hong Kong
Prior art keywords
diagnosis
cancer
compositions
treatment
methods
Prior art date
Application number
HK14112558.3A
Other languages
English (en)
Inventor
Karen Chapman
Joseph Wagner
Michael West
Jennifer Lorrie Kidd
Maria Prendes
Marcus Lacher
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of HK1199099A1 publication Critical patent/HK1199099A1/zh

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
HK14112558.3A 2011-08-31 2014-12-15 用於治療和診斷癌症的方法和組合物 HK1199099A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161529500P 2011-08-31 2011-08-31
US201161542403P 2011-10-03 2011-10-03
PCT/US2012/053472 WO2013033609A2 (en) 2011-08-31 2012-08-31 Methods and compositions for the treatment and diagnosis of cancer

Publications (1)

Publication Number Publication Date
HK1199099A1 true HK1199099A1 (zh) 2015-06-19

Family

ID=47757190

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14112558.3A HK1199099A1 (zh) 2011-08-31 2014-12-15 用於治療和診斷癌症的方法和組合物

Country Status (9)

Country Link
US (1) US20140206574A1 (zh)
EP (1) EP2751570A4 (zh)
JP (1) JP2014525584A (zh)
KR (1) KR20140057361A (zh)
CN (1) CN103890587A (zh)
AU (1) AU2012301664A1 (zh)
CA (1) CA2844793A1 (zh)
HK (1) HK1199099A1 (zh)
WO (1) WO2013033609A2 (zh)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2294216A4 (en) 2008-05-14 2011-11-23 Dermtech Int DIAGNOSIS OF MELANOMA AND SOLAR LENTIGO BY ANALYSIS OF NUCLEIC ACIDS
WO2014055398A1 (en) 2012-10-05 2014-04-10 Siemens Healthcare Diagnostics Inc. Method for detecting an increased risk or incidence of colorectal cancer
EP2853596A1 (en) * 2013-09-30 2015-04-01 IKBT (Institut für Klinische Biomedizinische Forschung Thurgau) Protein phosphatase inhibitor
GB201320061D0 (en) * 2013-11-13 2013-12-25 Electrophoretics Ltd Materials nad methods for diagnosis and prognosis of liver cancer
EP2876442A1 (en) 2013-11-22 2015-05-27 Institut de Cancérologie de l'Ouest Olfactomedin-4, neudesin and desmoplakin as biomarkers of breast cancer
JP2017509351A (ja) * 2013-12-30 2017-04-06 ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド 前立腺癌遺伝子プロファイル及びその使用方法
KR101779147B1 (ko) * 2014-07-04 2017-09-20 연세대학교 산학협력단 Kiaa1199를 이용한 췌장암의 진단 또는 치료용 조성물
CN105675735B (zh) * 2014-11-19 2018-07-17 上海市第六人民医院 乳腺癌诊断标记物组合、应用及其测定方法
JP6551967B2 (ja) * 2015-01-30 2019-07-31 国立大学法人山口大学 肝細胞がんの転移性再発リスクの予測方法
WO2016143697A1 (ja) * 2015-03-06 2016-09-15 国立大学法人名古屋大学 Syt13、syt8、anos1発現量による胃癌腹膜播種の検査方法、検査キット、分子標的治療薬スクリーニング方法、及び治療薬
GB201504502D0 (en) * 2015-03-17 2015-04-29 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
JP2016214239A (ja) * 2015-05-15 2016-12-22 国立大学法人高知大学 膵がんマーカー
JP6659250B2 (ja) * 2015-06-19 2020-03-04 国立大学法人滋賀医科大学 癌の検査方法、癌細胞増殖阻害剤、抗癌剤及び抗癌剤のスクリーニング方法
CN105463070B (zh) * 2015-07-08 2018-12-28 上海市同仁医院 Uca1基因在制备诊断结直肠癌产品中的应用
US10370647B2 (en) * 2015-07-22 2019-08-06 National University Corporation Tottori University Host regulatory factor that enhances replication and/or propagation of vaccinia virus
US20190316204A1 (en) * 2015-07-24 2019-10-17 Korea University Research And Business Foundation Biomarker for determining aging, determining obesity, and diagnosing cancer and diagnosing kit using same
US20170089905A1 (en) 2015-09-28 2017-03-30 Abbott Japan Co., Ltd. Methods of diagnosing hepatocellular carcinoma and pancreatic cancer
JP2019507582A (ja) * 2015-12-04 2019-03-22 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 免疫療法用のslc45a2ペプチド
WO2017113565A1 (zh) * 2015-12-29 2017-07-06 中国医学科学院肿瘤医院 基于蛋白标志物psg3辅助诊断肝癌或消化道癌症患者的试剂盒
CN105504060B (zh) * 2015-12-31 2018-10-26 陆梅生 一种抗胃癌细胞表面功能性表达的足萼样蛋白前体亚型2的单克隆抗体及其制备方法和用途
US10294297B2 (en) 2016-01-29 2019-05-21 The Board Of Trustees Of The Leland Stanford Junior University Methods for treatment using anti-NMU agents
CN106399306B (zh) * 2016-04-12 2019-11-05 西安交通大学第一附属医院 靶向人lncRNA-UCA1抑制膀胱癌的sgRNA、基因载体及其应用
SE540173C2 (en) * 2016-04-20 2018-04-24 Hiloprobe Ab Marker genes for colorectal cancer classification, method for judging lymph node metastasis for prognosis of colorectal cancer and kit therefor
CN106047874B (zh) * 2016-06-02 2019-01-18 吉林大学 一种靶向sall4基因的脱氧核酶分子及在乳腺癌基因治疗中的应用
EP3468546A4 (en) 2016-06-09 2020-04-01 Cedars-Sinai Medical Center COMPOSITIONS AND METHODS FOR TREATING CANCER
CN108329387B (zh) * 2017-01-17 2021-07-27 复旦大学附属肿瘤医院 癌症相关的肿瘤特异转录本lin28b-tst及其用途
WO2018210275A1 (en) * 2017-05-16 2018-11-22 The Chinese University Of Hong Kong Integrative single-cell and cell-free plasma rna analysis
WO2018218737A1 (zh) * 2017-06-01 2018-12-06 立森印迹诊断技术(无锡)有限公司 一种印记基因在膀胱肿瘤中的分级模型及其组成的系统
CN107312096B (zh) * 2017-07-17 2019-12-20 湖北大学 用于检测组蛋白位点三甲基化修饰的重组蛋白及其应用
CN107449916B (zh) * 2017-07-27 2019-05-21 北京邦菲生物科技有限公司 肺癌和肺部结节蛋白特征谱及其构建方法与应用
CN107807243B (zh) * 2017-11-24 2020-08-07 暨南大学 一种食管癌的生物标志物及其应用
CN108152496B (zh) * 2017-11-24 2020-10-27 暨南大学 Mest蛋白在制备肺癌辅助诊断和/或预后判断的试剂盒中的应用
WO2019118771A1 (en) * 2017-12-13 2019-06-20 Inovio Pharmaceuticals, Inc. Cancer vaccines targeting lemd1 and uses thereof
CA3090785A1 (en) 2018-02-14 2019-08-22 John Daniel Dobak Iii Novel gene classifiers and uses thereof in non-melanoma skin cancers
GB201803750D0 (en) * 2018-03-08 2018-04-25 Immunocore Ltd Method
KR20210016362A (ko) * 2018-05-29 2021-02-15 투룬 일리오피스토 결장암 예측 바이오마커로서의 l1td1
CN108796079B (zh) * 2018-06-06 2021-07-27 天津医科大学肿瘤医院 一种逆转录转座基因l1-fggy及其作为肺鳞癌标志物的用途
CN109116023B (zh) * 2018-06-14 2021-06-04 郑州大学第一附属医院 一种肺癌标志物抗-mmp12自身抗体及其应用
US11746387B2 (en) 2018-06-20 2023-09-05 Pontificia Universidad Catolica De Chile Non-invasive detection of gastric cancer by detecting the methylation of Reprimo-like in the blood
US20210275596A1 (en) * 2018-07-20 2021-09-09 Cell2In, Inc. Application of gene profile for cells isolated using fresh-tracer
CN109082473A (zh) * 2018-10-16 2018-12-25 兰州大学 一种公牛znf280ay基因拷贝数变异的检测方法及应用
JP7216995B2 (ja) * 2018-12-05 2023-02-02 学校法人関西医科大学 胸腺癌バイオマーカー及び胸腺腫瘍の予後予測マーカー
CN109371023A (zh) * 2018-12-11 2019-02-22 宁夏医科大学总医院 一种环状RNA hsa_circKIAA1199_006及其特异性扩增引物和应用
CA3134936A1 (en) 2019-03-26 2020-10-01 Dermtech, Inc. Novel gene classifiers and uses thereof in skin cancers
WO2020223392A2 (en) * 2019-04-30 2020-11-05 Totient, Inc. Cancer associated antibody compositions and methods of use
CN110218796B (zh) * 2019-06-27 2020-01-17 江门市中心医院 用于乳腺癌骨转移诊疗的新靶标pcdhb2
CN112147324A (zh) * 2019-06-28 2020-12-29 欧蒙医学实验诊断股份公司 自身抗体的检测
US20220357329A1 (en) * 2019-07-01 2022-11-10 Accure Health Inc. Predictive liquid markers for cancer immunotherapy
CN110796625B (zh) * 2019-10-30 2023-06-20 重庆邮电大学 一种基于组稀疏表示和加权全变分的图像压缩感知重构方法
CN111218509B (zh) * 2019-12-23 2023-07-04 西南医科大学附属医院 乳腺癌的新诊断标志物ppef1及其应用
WO2021231327A2 (en) * 2020-05-12 2021-11-18 Memorial Sloan Kettering Cancer Center Methods for de-cloaking cancer from the immune system through downregulation of cancer-produced pregnancy specific glycoprotein
CN112626210A (zh) * 2020-12-22 2021-04-09 上海市第一人民医院 诊断标志物gata4在胰腺“炎癌转化”中的应用
CN113504370B (zh) * 2021-06-29 2024-02-09 广州金研生物医药研究院有限公司 Mapk15蛋白在前列腺癌的恶性程度或预后程度预测中的应用
CN115537464B (zh) * 2021-06-30 2023-06-20 武汉艾米森生命科技有限公司 一种结直肠癌或癌前病变的诊断或辅助诊断试剂、核酸组合、试剂盒及应用
CN113980963A (zh) * 2021-09-03 2022-01-28 中山大学 一种寡核苷酸rna双链分子及其在制备治疗恶性肿瘤药物中的应用
CN114807369A (zh) * 2021-11-15 2022-07-29 四川大学华西医院 一种与前列腺癌显著相关的潜在抗原、免疫分型及其构建方法和应用
CN115992229B (zh) * 2022-07-22 2023-07-07 中南大学湘雅三医院 一种胰腺癌预后风险评估的lncRNA标记物、模型及其应用
CN115960253A (zh) * 2022-08-30 2023-04-14 暨南大学 一种肿瘤T细胞抗原表位肽、pMHC及其制备和应用
CN115786518A (zh) * 2022-11-29 2023-03-14 广东医科大学附属医院 嗅素结构域家族蛋白4(olfm4)在结肠癌检测产品中的应用
CN116482365B (zh) * 2023-03-14 2023-10-20 南京芯原生物科技有限公司 用于检测血清抗体的蛋白组合物及其应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ525320A (en) * 2000-10-18 2004-10-29 Glaxosmithkline Biolog S Combinations of immunostimulatory oligonucleotides (CpG), saponin and optionally lipopolysaccharides as potent vaccine adjuvants
AU2002322280A1 (en) * 2001-06-21 2003-01-21 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
WO2003057916A2 (en) * 2002-01-09 2003-07-17 Riken Cancer profiles
US20060188889A1 (en) * 2003-11-04 2006-08-24 Christopher Burgess Use of differentially expressed nucleic acid sequences as biomarkers for cancer
EP3470535B1 (en) * 2003-06-24 2020-04-01 Genomic Health, Inc. Prediction of likelihood of cancer recurrence
US20050208499A1 (en) * 2004-02-04 2005-09-22 Graff Jonathan M Markers for diagnosing and treating breast and ovarian cancer
DK1781814T3 (da) * 2004-08-10 2010-05-03 Cardiff Biolog Ltd Fremgangsmåder og kit til prognose af brystkræft
CN101194027B (zh) * 2005-06-08 2012-10-24 日立化成研究中心公司 用于基于瘤细胞及受刺激的白细胞内mRNA表达谱而预测对肿瘤疾病的免疫应答的方法
US20070218512A1 (en) * 2006-02-28 2007-09-20 Alex Strongin Methods related to mmp26 status as a diagnostic and prognostic tool in cancer management
DE102006024416A1 (de) * 2006-05-24 2008-04-30 Friedrich-Alexander-Universität Erlangen-Nürnberg Prädiktives Genexpressionsmuster für kolorektale Karzinome
ES2444695T3 (es) * 2006-06-23 2014-02-26 Alethia Biotherapeutics Inc. Polinucleótidos y polipéptidos implicados en el cáncer
RU2473555C2 (ru) * 2006-12-19 2013-01-27 ДжинГоу, Инк. Новые способы функционального анализа большого количества экспериментальных данных и групп генов, идентифицированных из указанных данных
AT504702A1 (de) * 2006-12-22 2008-07-15 Arc Austrian Res Centers Gmbh Set von tumormarkern
WO2008089577A1 (en) * 2007-01-26 2008-07-31 Vm Institute Of Resaerch Breast cancer gene array
EP2048242A1 (de) * 2007-10-08 2009-04-15 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Microarray für die Expressionsanalyse der zellulären Glykosylierungsmaschinerie
AU2008316319A1 (en) * 2007-10-23 2009-04-30 Clinical Genomics Pty. Ltd. A method of diagnosing neoplasms
EP2281201B1 (en) * 2008-05-14 2018-03-28 ETH Zurich Method for biomarker and drug-target discovery for prostate cancer diagnosis and treatment as well as biomarker assays determined therewith
US8945849B2 (en) * 2008-05-21 2015-02-03 Toray Industries, Inc. Method for diagnosing esophageal cancer
EP2350316B1 (en) * 2008-10-20 2014-04-16 ValiPharma Methods and uses involving genetic aberrations of nav3 and aberrant expression of multiple genes
CA3153682A1 (en) * 2008-11-17 2010-05-20 Veracyte, Inc. Methods and compositions of molecular profiling for disease diagnostics
KR20120034593A (ko) * 2009-03-09 2012-04-12 유니버시티 오브 조지아 리서치 파운데이션 인코퍼레이티드 위암 진단용 단백질 마커의 동정
EP2464231A4 (en) * 2009-08-10 2013-02-06 Samumed Llc INDAZOLE AS WNT / B-CATENINE SIGNALING PATHWASHER AND THERAPEUTIC APPLICATIONS THEREOF
EP2538981B1 (en) * 2010-02-23 2017-12-20 F. Hoffmann-La Roche AG Compositions and methods for the diagnosis and treatment of tumor

Also Published As

Publication number Publication date
CA2844793A1 (en) 2013-03-07
WO2013033609A2 (en) 2013-03-07
CN103890587A (zh) 2014-06-25
KR20140057361A (ko) 2014-05-12
US20140206574A1 (en) 2014-07-24
JP2014525584A (ja) 2014-09-29
WO2013033609A3 (en) 2013-06-27
EP2751570A2 (en) 2014-07-09
AU2012301664A1 (en) 2014-02-27
EP2751570A4 (en) 2015-08-12

Similar Documents

Publication Publication Date Title
HK1199099A1 (zh) 用於治療和診斷癌症的方法和組合物
HK1199100A1 (zh) 用於治療和診斷結直腸癌的方法和組合物
HK1202313A1 (zh) 治療和診斷膀胱癌的方法和組合物
EP2723924A4 (en) METHOD AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF CANCER
EP2688594A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
HK1178074A1 (zh) 用於腫瘤診斷和治療的組合物和方法
EP2890815A4 (en) METHOD FOR THE DIAGNOSIS AND TREATMENT OF CANCER
EP2714081A4 (en) METHODS, COMPOSITIONS AND KIT FOR CREAM TREATMENT
HK1200739A1 (zh) 用於治療癌症的診斷方法和組合物
IL225471A0 (en) Preparations and methods for the prevention and treatment of cancer
GB201115711D0 (en) Phyto-cannabinoids for use in the treatment of cancer
IL238177A0 (en) Methods and preparations for the treatment of cancer
HK1199290A1 (zh) 用於治療和診斷乳腺癌的方法和組合物
HK1197276A1 (zh) 治療及診斷膀胱癌的方法和組合物
EP2654745A4 (en) COMPOSITION FOR TREATING SKIN CONDITIONS OF THE SKIN
IL251083B (en) Compounds and preparations for the treatment of cancer
HK1201045A1 (zh) 用於腫瘤診斷和治療的組合物和方法
EP2558085A4 (en) COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CANCER
IL225793A0 (en) Methods and preparations for curing insulin-related medical conditions
PL2605764T3 (pl) Kompozycje do leczenia nowotworu
EP2709632A4 (en) COMPOSITIONS AND METHOD FOR THE TREATMENT OF SKIN DISEASES
EP2687231A4 (en) COMPOSITION FOR THE TREATMENT AND DIAGNOSIS OF PANCREATIC CANCER
EP2928456A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
EP2547368A4 (en) METHOD AND COMPOSITIONS FOR CANCER TREATMENT
EP3603631C0 (en) METHODS AND COMPOSITIONS FOR TREATING DIVERTICULOSIS