HK1184462A1 - Monobactams - Google Patents

Monobactams

Info

Publication number
HK1184462A1
HK1184462A1 HK13111964.4A HK13111964A HK1184462A1 HK 1184462 A1 HK1184462 A1 HK 1184462A1 HK 13111964 A HK13111964 A HK 13111964A HK 1184462 A1 HK1184462 A1 HK 1184462A1
Authority
HK
Hong Kong
Prior art keywords
monobactams
Prior art date
Application number
HK13111964.4A
Other languages
English (en)
Chinese (zh)
Inventor
.布朗
.米頓-弗賴伊
.韓
.拉爾
.普盧默
.裡斯利
.桑穆加孫達拉姆
.斯塔爾
Original Assignee
輝瑞大藥廠
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 輝瑞大藥廠 filed Critical 輝瑞大藥廠
Publication of HK1184462A1 publication Critical patent/HK1184462A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK13111964.4A 2010-11-29 2013-10-24 Monobactams HK1184462A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41757510P 2010-11-29 2010-11-29
PCT/IB2011/055104 WO2012073138A1 (en) 2010-11-29 2011-11-15 Monobactams

Publications (1)

Publication Number Publication Date
HK1184462A1 true HK1184462A1 (en) 2014-01-24

Family

ID=45315854

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13111964.4A HK1184462A1 (en) 2010-11-29 2013-10-24 Monobactams

Country Status (18)

Country Link
US (3) US20120302542A1 (xx)
EP (1) EP2646436B1 (xx)
JP (1) JP5777725B2 (xx)
KR (1) KR101514587B1 (xx)
CN (1) CN103228652B (xx)
AR (1) AR084001A1 (xx)
AU (1) AU2011336209B2 (xx)
CA (1) CA2815821C (xx)
DK (1) DK2646436T3 (xx)
ES (1) ES2542431T3 (xx)
HK (1) HK1184462A1 (xx)
IL (1) IL226052A0 (xx)
MX (1) MX2013005994A (xx)
SG (1) SG190007A1 (xx)
TW (1) TW201247661A (xx)
UY (1) UY33754A (xx)
WO (1) WO2012073138A1 (xx)
ZA (1) ZA201304479B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015099107A1 (ja) 2013-12-26 2015-07-02 塩野義製薬株式会社 含窒素6員環誘導体およびそれらを含有する医薬組成物
AU2015236369B2 (en) 2014-03-24 2017-02-16 Novartis Ag Monobactam organic compounds for the treatment of bacterial infections
AU2016327264B2 (en) * 2015-09-23 2019-06-27 Novartis Ag Salts and solid forms of monobactam antibiotic
CN105481812B (zh) * 2015-11-30 2020-04-21 重庆天奕恒化科技有限公司 一种5-苄氧基-4-氧代-4h-吡喃-2-羧酸的制备方法
EP3390357B1 (en) 2015-12-15 2021-11-10 Merck Sharp & Dohme Corp. Biaryl monobactam compounds for the treatment of bacterial infections
MX2018010878A (es) 2016-03-07 2018-11-09 Merck Sharp & Dohme Compuestos de aril-monobactam biciclicos y metodos de uso de los mismos para el tratamiento de infecciones bacterianas.
US10047077B2 (en) 2016-04-13 2018-08-14 Skyline Antiinfectives, Inc. Deuterated O-sulfated beta-lactam hydroxamic acids and deuterated N-sulfated beta-lactams
CN107641119B (zh) 2016-07-21 2019-11-08 中国科学院上海药物研究所 单环β-内酰胺-铁载体轭合物及其制备方法和用途
US11414411B2 (en) 2017-08-02 2022-08-16 Novartis Ag Chemical process for manufacturing monobactam antibiotic and intermediates thereof
CA3076022C (en) 2017-10-02 2023-01-17 Merck Sharp & Dohme Corp. Chromane monobactam compounds for the treatment of bacterial infections
US10513504B2 (en) 2018-03-08 2019-12-24 Apotex Inc. Processes for the preparation of apalutamide and intermediates thereof
JP7446424B2 (ja) * 2019-11-22 2024-03-08 スージョウ アーイェ ファーマシューティカル カンパニー リミテッド スルホニル尿素環置換単環式β-ラクタム系抗生物質
AR120680A1 (es) 2019-12-06 2022-03-09 Vertex Pharma Tetrahidrofuranos sustituidos como moduladores de canales de sodio
CN111303144B (zh) * 2019-12-13 2020-11-27 苏州信诺维医药科技有限公司 一种治疗细菌感染的化合物
KR20220152157A (ko) * 2021-05-07 2022-11-15 한국생명공학연구원 신규 사이드로포어 화합물 및 이를 이용한 금속 나노입자 복합체
AR126073A1 (es) 2021-06-04 2023-09-06 Vertex Pharma N-(hidroxialquil(hetero)aril)tetrahidrofuran carboxamidas como moduladores de canales de sodio
KR20240105442A (ko) 2021-11-18 2024-07-05 머크 샤프 앤드 돔 엘엘씨 크로만 아미딘 모노박탐 항생제
CN115304594B (zh) * 2022-10-12 2023-02-14 苏州二叶制药有限公司 磺酰脲环取代的化合物的盐型及其晶型

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7541487A (en) * 1986-05-23 1987-12-22 Upjohn Company, The N-1 substituted sulfonylaminocarbonyl, c-4 substituted monobactams
CN103724330B (zh) * 2005-12-07 2015-08-19 巴斯利尔药物股份公司 单环-内酰胺类抗生素与β-内酰胺酶抑制剂的有效的联合应用
AU2008232262B2 (en) 2007-03-28 2013-02-14 Apotex Inc. Fluorinated derivatives of deferiprone
CN102325769A (zh) 2008-12-19 2012-01-18 美国辉瑞有限公司 单卡波姆

Also Published As

Publication number Publication date
IL226052A0 (en) 2013-06-27
TW201247661A (en) 2012-12-01
JP5777725B2 (ja) 2015-09-09
JP2013544276A (ja) 2013-12-12
KR101514587B1 (ko) 2015-04-22
WO2012073138A1 (en) 2012-06-07
CA2815821A1 (en) 2012-06-07
MX2013005994A (es) 2013-07-15
EP2646436B1 (en) 2015-05-27
DK2646436T3 (en) 2015-06-29
AU2011336209B2 (en) 2015-03-19
ZA201304479B (en) 2014-03-26
CA2815821C (en) 2015-07-07
ES2542431T3 (es) 2015-08-05
KR20130112054A (ko) 2013-10-11
SG190007A1 (en) 2013-06-28
AU2011336209A1 (en) 2013-05-30
UY33754A (es) 2012-06-29
US20150148326A1 (en) 2015-05-28
CN103228652B (zh) 2015-02-18
US20130252935A1 (en) 2013-09-26
EP2646436A1 (en) 2013-10-09
US20120302542A1 (en) 2012-11-29
AR084001A1 (es) 2013-04-17
CN103228652A (zh) 2013-07-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181113