HK1182694A1 - Peripheral opioid receptor and antagonists and uses thereof - Google Patents

Peripheral opioid receptor and antagonists and uses thereof

Info

Publication number
HK1182694A1
HK1182694A1 HK13109877.4A HK13109877A HK1182694A1 HK 1182694 A1 HK1182694 A1 HK 1182694A1 HK 13109877 A HK13109877 A HK 13109877A HK 1182694 A1 HK1182694 A1 HK 1182694A1
Authority
HK
Hong Kong
Prior art keywords
antagonists
opioid receptor
peripheral opioid
peripheral
receptor
Prior art date
Application number
HK13109877.4A
Other languages
English (en)
Chinese (zh)
Inventor
Charles K Melucci
John Lokhnauth
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of HK1182694A1 publication Critical patent/HK1182694A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
HK13109877.4A 2007-03-29 2013-08-23 Peripheral opioid receptor and antagonists and uses thereof HK1182694A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92072207P 2007-03-29 2007-03-29

Publications (1)

Publication Number Publication Date
HK1182694A1 true HK1182694A1 (en) 2013-12-06

Family

ID=39577863

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13109877.4A HK1182694A1 (en) 2007-03-29 2013-08-23 Peripheral opioid receptor and antagonists and uses thereof

Country Status (14)

Country Link
US (2) US8338446B2 (xx)
EP (2) EP2565195B1 (xx)
JP (1) JP5469593B2 (xx)
CA (1) CA2682550C (xx)
DK (2) DK2565195T3 (xx)
ES (2) ES2493590T3 (xx)
HK (1) HK1182694A1 (xx)
HR (2) HRP20140768T1 (xx)
HU (1) HUE025662T2 (xx)
MX (2) MX2009010515A (xx)
PL (2) PL2565195T3 (xx)
PT (2) PT2139890E (xx)
SI (2) SI2565195T1 (xx)
WO (1) WO2008121860A1 (xx)

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AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
TW200815451A (en) 2006-08-04 2008-04-01 Wyeth Corp 6-carboxy-normorphinan derivatives, synthesis and uses thereof
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
TWI466671B (zh) 2007-03-29 2015-01-01 Progenics Pharm Inc 末梢性類鴉片受體拮抗劑及其用途
EP3263571B2 (en) 2007-03-29 2023-08-23 Progenics Pharmaceuticals, Inc. Crystal form of (r)-n-methylnaltrexone bromide and uses thereof
MX2009010515A (es) 2007-03-29 2009-10-19 Wyeth Corp Antagonistas del receptor opioide periferico y usos de los mismos.
CN101959892B (zh) 2008-02-06 2014-01-08 普罗热尼奇制药公司 (r),(r)-2,2’-二-甲基纳曲酮的制备和用途
CA2676881C (en) * 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
AU2016201221B2 (en) * 2008-09-30 2017-08-10 Wyeth Llc Peripheral opioid receptor antagonists and uses thereof
AU2013203119B2 (en) * 2008-09-30 2015-12-03 Wyeth Llc Peripheral opioid receptor antagonists and uses thereof
WO2011112816A1 (en) 2010-03-11 2011-09-15 Wyeth, Llc Oral formulations and lipophilic salts of methylnaltrexone

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