HK1175781A1 - Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h- pyrrole-3-carbox-amides 5-(2---4-)-2--1h--3- - Google Patents

Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h- pyrrole-3-carbox-amides 5-(2---4-)-2--1h--3-

Info

Publication number
HK1175781A1
HK1175781A1 HK13103041.8A HK13103041A HK1175781A1 HK 1175781 A1 HK1175781 A1 HK 1175781A1 HK 13103041 A HK13103041 A HK 13103041A HK 1175781 A1 HK1175781 A1 HK 1175781A1
Authority
HK
Hong Kong
Prior art keywords
carbox
pyrimidin
pyrrole
amides
aryl
Prior art date
Application number
HK13103041.8A
Other languages
English (en)
Chinese (zh)
Inventor
.丹納羅
.雷
Original Assignee
內爾維阿諾醫學科學有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 內爾維阿諾醫學科學有限公司 filed Critical 內爾維阿諾醫學科學有限公司
Publication of HK1175781A1 publication Critical patent/HK1175781A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK13103041.8A 2009-11-04 2013-03-12 Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h- pyrrole-3-carbox-amides 5-(2---4-)-2--1h--3- HK1175781A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09175063 2009-11-04
PCT/EP2010/066241 WO2011054714A1 (en) 2009-11-04 2010-10-27 Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h-pyrrole-3-carboxamides

Publications (1)

Publication Number Publication Date
HK1175781A1 true HK1175781A1 (en) 2013-07-12

Family

ID=43431011

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13103041.8A HK1175781A1 (en) 2009-11-04 2013-03-12 Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h- pyrrole-3-carbox-amides 5-(2---4-)-2--1h--3-

Country Status (15)

Country Link
US (1) US8592583B2 (pt)
EP (1) EP2496570B1 (pt)
JP (1) JP5715146B2 (pt)
CN (1) CN102666527B (pt)
AR (1) AR078883A1 (pt)
AU (1) AU2010314204B2 (pt)
BR (1) BR112012010445B1 (pt)
CA (1) CA2779785C (pt)
CL (1) CL2012001140A1 (pt)
EA (1) EA021299B1 (pt)
ES (1) ES2593630T3 (pt)
HK (1) HK1175781A1 (pt)
MX (1) MX339634B (pt)
TW (1) TWI478914B (pt)
WO (1) WO2011054714A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013026137B1 (pt) * 2011-04-19 2020-12-01 Nerviano Medical Sciences S.R.L pirimidinil-pirróis substituídos ativos como inibidores da quinase
CN107915720B (zh) * 2016-10-08 2020-09-11 常州市第四制药厂有限公司 沃诺拉赞的新制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09295967A (ja) * 1996-05-02 1997-11-18 Sumitomo Metal Ind Ltd 新規ピロールアルカン酸誘導体
SE0202463D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab Novel compounds
JP2007519754A (ja) * 2004-01-30 2007-07-19 スミスクライン ビーチャム コーポレーション 化合物
JP5212101B2 (ja) * 2005-09-02 2013-06-19 アステラス製薬株式会社 新規化合物
KR20090008286A (ko) 2006-03-27 2009-01-21 네르비아노 메디칼 사이언시스 에스.알.엘. 키나제 억제제로서의 피리딜- 및 피리미디닐-치환된 피롤-,티오펜- 및 푸란- 유도체
TWI426074B (zh) * 2008-04-30 2014-02-11 Nerviano Medical Sciences Srl 5-(2-胺基-嘧啶-4-基)-2-芳基-1h-吡咯-3-羧醯胺之製造方法

Also Published As

Publication number Publication date
US8592583B2 (en) 2013-11-26
ES2593630T3 (es) 2016-12-12
MX339634B (es) 2016-06-02
US20120220771A1 (en) 2012-08-30
EA201290276A1 (ru) 2012-12-28
CN102666527B (zh) 2014-10-01
JP2013510110A (ja) 2013-03-21
CL2012001140A1 (es) 2012-08-31
WO2011054714A1 (en) 2011-05-12
EP2496570B1 (en) 2016-06-29
EA021299B1 (ru) 2015-05-29
AU2010314204A1 (en) 2012-06-21
BR112012010445A2 (pt) 2015-09-29
AU2010314204B2 (en) 2015-03-26
TWI478914B (zh) 2015-04-01
JP5715146B2 (ja) 2015-05-07
MX2012004844A (es) 2012-06-12
EP2496570A1 (en) 2012-09-12
AR078883A1 (es) 2011-12-07
BR112012010445B1 (pt) 2021-09-21
CA2779785A1 (en) 2011-05-12
CA2779785C (en) 2017-09-12
TW201121954A (en) 2011-07-01
CN102666527A (zh) 2012-09-12

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20231029