PL2387566T3 - Sposób przygotowania rosuwastatyny - Google Patents

Sposób przygotowania rosuwastatyny

Info

Publication number
PL2387566T3
PL2387566T3 PL10700989T PL10700989T PL2387566T3 PL 2387566 T3 PL2387566 T3 PL 2387566T3 PL 10700989 T PL10700989 T PL 10700989T PL 10700989 T PL10700989 T PL 10700989T PL 2387566 T3 PL2387566 T3 PL 2387566T3
Authority
PL
Poland
Prior art keywords
rosuvastatin
preparation
Prior art date
Application number
PL10700989T
Other languages
English (en)
Inventor
Primoz Benkic
David Bevk
Roman Lenarsic
Silvo Zupancic
Anamarija Vajs
David Jakse
Original Assignee
Krka Tovarna Zdravil D D Novo Mesto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka Tovarna Zdravil D D Novo Mesto filed Critical Krka Tovarna Zdravil D D Novo Mesto
Publication of PL2387566T3 publication Critical patent/PL2387566T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL10700989T 2009-01-14 2010-01-14 Sposób przygotowania rosuwastatyny PL2387566T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SI200900012 2009-01-14
SI200900217 2009-07-31
PCT/EP2010/050425 WO2010081861A1 (en) 2009-01-14 2010-01-14 Process for the preparation of rosuvastatin
EP10700989.6A EP2387566B1 (en) 2009-01-14 2010-01-14 Process for the preparation of rosuvastatin

Publications (1)

Publication Number Publication Date
PL2387566T3 true PL2387566T3 (pl) 2014-10-31

Family

ID=42026244

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10700989T PL2387566T3 (pl) 2009-01-14 2010-01-14 Sposób przygotowania rosuwastatyny

Country Status (7)

Country Link
EP (2) EP2387566B1 (pl)
CN (1) CN102282136B (pl)
EA (1) EA019995B1 (pl)
HR (1) HRP20140723T1 (pl)
PL (1) PL2387566T3 (pl)
SI (2) SI2752407T1 (pl)
WO (1) WO2010081861A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA021942B1 (ru) * 2009-01-15 2015-10-30 Эгиш Дьёдьсердьяр Зрт. Способ изготовления солей розувастатина
US8470805B2 (en) * 2009-04-30 2013-06-25 Kaohsiung Medical University Processes for preparing piperazinium salts of KMUP and use thereof
WO2012063115A2 (en) * 2010-11-11 2012-05-18 Jubilant Life Sciences Ltd. Process for the preparation of rosuvastatin calcium via novel amine intermediate
HU230987B1 (hu) * 2010-11-29 2019-08-28 Egis Gyógyszergyár Nyrt. Eljárás nagy tisztaságú gyógyszeripari intermedierek előállítására
WO2012073256A1 (en) 2010-11-29 2012-06-07 Cadila Healthcare Limited Salts of rosuvastatin
HU229260B1 (en) * 2010-11-29 2013-10-28 Egis Gyogyszergyar Nyrt Process for preparation of rosuvastatin salts
EP2602249B1 (en) * 2011-12-06 2015-08-12 F.I.S. Fabbrica Italiana Sintetici S.p.A. Synthesis of rosuvastatin by means of co-crystals
WO2014050874A1 (ja) * 2012-09-27 2014-04-03 東和薬品株式会社 ロスバスタチンカルシウムの新規結晶形態およびその製造方法
CN103387560B (zh) * 2013-07-04 2015-01-07 复旦大学 2-[(4r,6s)-6-取代甲基-2,2-二甲基-1,3-二氧六环]-乙酸酯的制备方法
US9850213B2 (en) * 2013-11-25 2017-12-26 Jiangxi Boya Seehot Pharmaceutical Co., Ltd. Method for preparing rosuvastatin sodium
CN111454216B (zh) * 2019-10-21 2021-06-29 山东理工职业学院 HMG-CoA还原酶抑制剂及其中间体的制备方法
WO2023152754A1 (en) * 2022-02-08 2023-08-17 Sawant, Mohit Manikrao Crystalline form of rosuvastatin allyl ester
CN115417824A (zh) * 2022-09-21 2022-12-02 安徽美诺华药物化学有限公司 一种瑞舒伐他汀中间体的高纯度制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5093363A (en) 1989-08-22 1992-03-03 Shionogi & Co., Ltd. 2,4,6-substituted phenol derivatives
US5214197A (en) 1990-07-06 1993-05-25 Kanegafuchi Chemical Industry Co., Ltd. 2,4-dihydroxyadipic acid derivative
EP0469480A3 (en) 1990-08-01 1993-03-10 Hoechst Aktiengesellschaft Process for stereoselective preparation of 5-substituted delta-lactones and their use
JP2648897B2 (ja) 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
US5278313A (en) 1992-03-27 1994-01-11 E. R. Squibb & Sons, Inc. Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors
GB9903472D0 (en) 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
GB0003305D0 (en) * 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
EP1585736A2 (en) 2002-05-21 2005-10-19 Ranbaxy Laboratories, Ltd. Process for the preparation of rosuvastatin
UY28501A1 (es) * 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
TW200526596A (en) * 2003-11-24 2005-08-16 Teva Pharma Crystalline ammonium salts of rosuvastatin
CN1906175A (zh) * 2003-11-24 2007-01-31 特瓦制药工业有限公司 罗苏伐他汀的结晶铵盐
WO2005054207A1 (en) 2003-12-04 2005-06-16 Glenmark Pharmaceuticals Limited Process for the preparation of pyrimidine derivatives
EP1709008A1 (en) * 2004-01-19 2006-10-11 Ranbaxy Laboratories Limited Salts of hmg-coa reductase inhibitors and use thereof
US7179916B2 (en) 2004-07-13 2007-02-20 Teva Pharmaceutical Industries Ltd. Process for the preparation of rosuvastatin
JP2008528542A (ja) * 2005-01-31 2008-07-31 チバ ホールディング インコーポレーテッド ロスバスタチンカルシウム塩の結晶形
EP1893585A1 (en) 2005-06-01 2008-03-05 Fermion Oy Process for the preparation of n-[4-(4-fluorophenyl)-5-formyl-6-isopropyl-pyrimidin-2-yl]-n-methylmethanesulfonamide
WO2006136407A1 (en) * 2005-06-24 2006-12-28 Lek Pharmaceuticals D.D. Process for preparing amorphous rosuvastatin calcium free of impurities
WO2006136408A2 (en) * 2005-06-24 2006-12-28 Lek Pharmaceuticals D.D. Process for preparing pure amorphous rosuvastatin calcium
WO2007074391A2 (en) 2005-12-28 2007-07-05 Bakulesh Mafatlal Khamar Preparation of a key intermediate in the synthesis of rosuvastatin
CN1821242B (zh) 2006-02-16 2012-03-07 亚邦化工集团有限公司 制备二羟基酸HMG-CoA还原酶抑制剂的新方法
WO2007125547A2 (en) * 2006-05-03 2007-11-08 Manne Satyanarayana Reddy Novel process for statins and its pharmaceutically acceptable salts thereof
US8404841B2 (en) * 2006-10-09 2013-03-26 Msn Laboratories Limited Process for the preparation of statins and their pharmaceutically acceptable salts thereof
HUE035402T2 (en) 2008-06-27 2018-05-02 Krka Tovarna Zdravil D D Novo Mesto Pharmaceutical composition containing statin

Also Published As

Publication number Publication date
EA201190067A1 (ru) 2012-02-28
EP2752407A1 (en) 2014-07-09
WO2010081861A1 (en) 2010-07-22
SI2752407T1 (sl) 2016-07-29
EP2387566A1 (en) 2011-11-23
EP2387566B1 (en) 2014-05-07
CN102282136A (zh) 2011-12-14
EA019995B1 (ru) 2014-07-30
CN102282136B (zh) 2014-12-17
EP2752407B1 (en) 2015-09-23
SI2387566T1 (sl) 2014-07-31
HRP20140723T1 (hr) 2014-10-24

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