HK1169117A1 - Compound having detrusor muscle-contracting activity and urethral sphincter muscle-relaxing activity - Google Patents
Compound having detrusor muscle-contracting activity and urethral sphincter muscle-relaxing activityInfo
- Publication number
- HK1169117A1 HK1169117A1 HK12109940.8A HK12109940A HK1169117A1 HK 1169117 A1 HK1169117 A1 HK 1169117A1 HK 12109940 A HK12109940 A HK 12109940A HK 1169117 A1 HK1169117 A1 HK 1169117A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- activity
- muscle
- compound
- urethral sphincter
- contracting
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 210000005070 sphincter Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/26—Radicals substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009139657 | 2009-06-10 | ||
JP2009256008 | 2009-11-09 | ||
PCT/JP2010/059771 WO2010143661A1 (ja) | 2009-06-10 | 2010-06-09 | 膀胱排尿筋収縮および尿道括約筋弛緩作用を有する化合物 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1169117A1 true HK1169117A1 (en) | 2013-01-18 |
Family
ID=43308916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12109940.8A HK1169117A1 (en) | 2009-06-10 | 2012-10-10 | Compound having detrusor muscle-contracting activity and urethral sphincter muscle-relaxing activity |
Country Status (20)
Country | Link |
---|---|
US (3) | US8410281B2 (ru) |
EP (1) | EP2441760B1 (ru) |
JP (1) | JP4807478B2 (ru) |
KR (1) | KR101633149B1 (ru) |
CN (1) | CN102803239B (ru) |
AU (1) | AU2010259585B2 (ru) |
BR (1) | BRPI1013152B1 (ru) |
CA (1) | CA2764782C (ru) |
DK (1) | DK2441760T3 (ru) |
ES (1) | ES2444500T3 (ru) |
HK (1) | HK1169117A1 (ru) |
IL (1) | IL216856A0 (ru) |
MX (1) | MX2011013283A (ru) |
NZ (1) | NZ596960A (ru) |
PL (1) | PL2441760T3 (ru) |
PT (1) | PT2441760E (ru) |
RU (1) | RU2531350C2 (ru) |
TW (1) | TWI437987B (ru) |
WO (1) | WO2010143661A1 (ru) |
ZA (1) | ZA201109103B (ru) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ596960A (en) * | 2009-06-10 | 2013-04-26 | Ono Pharmaceutical Co | Compound having detrusor muscle-contracting activity and urethral sphincter muscle-relaxing activity |
PT2891651T (pt) * | 2012-08-31 | 2017-05-08 | Ono Pharmaceutical Co | Sal de amina e cristais do mesmo |
EP3027199B1 (en) | 2013-08-01 | 2019-06-26 | Dignify Therapeutics, LLC | Compositions and methods for inducing urinary voiding and defecation |
WO2016073294A1 (en) * | 2014-11-03 | 2016-05-12 | William Beaumont Hospital | Method for treating underactive bladder syndrome |
KR20210110792A (ko) | 2018-12-31 | 2021-09-09 | 아다마 마켓심 리미티드 | 1,1,2-트리플루오로-4-(치환 설포닐)-부트-1-엔의 합성 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS503362B1 (ru) | 1970-06-10 | 1975-02-04 | ||
JPS5231404B1 (ru) | 1971-04-28 | 1977-08-15 | ||
JPS57156460A (en) | 1981-03-20 | 1982-09-27 | Ono Pharmaceut Co Ltd | Stabilized composition of prostaglandin and prostaglandin mimic compound, and its preparation |
JPS60197667A (ja) | 1984-03-19 | 1985-10-07 | Ono Pharmaceut Co Ltd | 6―ケト―プロスタグランジン類似化合物及びその製造方法 |
US6288119B1 (en) | 1997-02-10 | 2001-09-11 | Ono Pharmaceuticals Co., Ltd. | 11,15-O-dialkylprostaglandin E derivatives, process for producing the same, and drugs containing the same as the active ingredient |
JPH11130678A (ja) | 1997-08-27 | 1999-05-18 | Kaken Pharmaceut Co Ltd | 神経圧迫による神経障害改善剤 |
TWI313608B (en) | 2001-07-23 | 2009-08-21 | Ono Pharmaceutical Co | Lower bone mass treating agent containing er4 agonist as active ingredient |
JP2005053707A (ja) | 2001-07-30 | 2005-03-03 | Kankyo Device Kenkyusho:Kk | 可視光応答性材料の製造方法 |
MXPA04008596A (es) | 2002-03-05 | 2004-12-06 | Ono Pharmaceutical Co | Compuestos derivados de 8-azaprostaglandina y farmacos que contienen los compuestos como ingrediente activo. |
AU2002345285A1 (en) | 2002-07-11 | 2004-02-02 | Nokia Corporation | Method and device for automatically changing a digital content on a mobile device according to sensor data |
US7256211B1 (en) | 2003-01-21 | 2007-08-14 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivatives and medical use thereof |
US20070167403A1 (en) | 2003-04-03 | 2007-07-19 | Yoshifumi Takenobu | Remedy for spinal canal stenosis |
JP5023492B2 (ja) * | 2003-12-05 | 2012-09-12 | 小野薬品工業株式会社 | 馬尾神経組織血流増加剤 |
JPWO2005061492A1 (ja) | 2003-12-22 | 2007-07-12 | 小野薬品工業株式会社 | 含窒素複素環化合物およびそれらを有効成分とする薬剤 |
EP1782830A4 (en) * | 2004-08-10 | 2009-07-29 | Ono Pharmaceutical Co | PREVENTION AND / OR REMEDY FOR LOWER URINARY TRACT DISEASES CONTAINING AN EP4 AGONIST |
US7858650B2 (en) | 2004-10-22 | 2010-12-28 | Ono Pharmaceutical Co., Ltd. | Medicinal composition for inhalation |
JP2006129788A (ja) | 2004-11-05 | 2006-05-25 | Nippon Starch Chemical Co Ltd | 揚げ物用ミックス |
EP1886693A4 (en) | 2005-06-03 | 2010-03-03 | Ono Pharmaceutical Co | ACTIVE AGENT FOR REGENERATING AND / OR PROTECTING NERVES |
JP5630264B2 (ja) * | 2008-06-06 | 2014-11-26 | 小野薬品工業株式会社 | 膀胱排尿筋収縮および尿道括約筋弛緩剤 |
NZ596960A (en) * | 2009-06-10 | 2013-04-26 | Ono Pharmaceutical Co | Compound having detrusor muscle-contracting activity and urethral sphincter muscle-relaxing activity |
-
2010
- 2010-06-09 NZ NZ596960A patent/NZ596960A/xx not_active IP Right Cessation
- 2010-06-09 CN CN201080035423.7A patent/CN102803239B/zh not_active Expired - Fee Related
- 2010-06-09 KR KR1020117029571A patent/KR101633149B1/ko active IP Right Grant
- 2010-06-09 MX MX2011013283A patent/MX2011013283A/es active IP Right Grant
- 2010-06-09 DK DK10786192.4T patent/DK2441760T3/en active
- 2010-06-09 JP JP2011503274A patent/JP4807478B2/ja active Active
- 2010-06-09 CA CA2764782A patent/CA2764782C/en active Active
- 2010-06-09 WO PCT/JP2010/059771 patent/WO2010143661A1/ja active Application Filing
- 2010-06-09 AU AU2010259585A patent/AU2010259585B2/en not_active Ceased
- 2010-06-09 PL PL10786192T patent/PL2441760T3/pl unknown
- 2010-06-09 RU RU2011152927/04A patent/RU2531350C2/ru active
- 2010-06-09 PT PT107861924T patent/PT2441760E/pt unknown
- 2010-06-09 US US13/377,047 patent/US8410281B2/en active Active
- 2010-06-09 EP EP10786192.4A patent/EP2441760B1/en active Active
- 2010-06-09 TW TW099118684A patent/TWI437987B/zh not_active IP Right Cessation
- 2010-06-09 BR BRPI1013152-3A patent/BRPI1013152B1/pt not_active IP Right Cessation
- 2010-06-09 ES ES10786192.4T patent/ES2444500T3/es active Active
-
2011
- 2011-12-08 IL IL216856A patent/IL216856A0/en active IP Right Grant
- 2011-12-09 ZA ZA2011/09103A patent/ZA201109103B/en unknown
-
2012
- 2012-10-10 HK HK12109940.8A patent/HK1169117A1/xx not_active IP Right Cessation
-
2013
- 2013-03-04 US US13/784,008 patent/US8716490B2/en active Active
-
2014
- 2014-02-12 US US14/178,901 patent/US9150528B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PL2441760T3 (pl) | 2014-05-30 |
TW201103539A (en) | 2011-02-01 |
JP4807478B2 (ja) | 2011-11-02 |
BRPI1013152A2 (pt) | 2016-04-05 |
KR101633149B1 (ko) | 2016-06-23 |
EP2441760A1 (en) | 2012-04-18 |
MX2011013283A (es) | 2012-01-12 |
US8410281B2 (en) | 2013-04-02 |
US20140171387A1 (en) | 2014-06-19 |
PT2441760E (pt) | 2014-01-07 |
US9150528B2 (en) | 2015-10-06 |
AU2010259585A1 (en) | 2012-01-19 |
DK2441760T3 (en) | 2014-02-17 |
JPWO2010143661A1 (ja) | 2012-11-29 |
KR20120026088A (ko) | 2012-03-16 |
CA2764782A1 (en) | 2010-12-16 |
EP2441760B1 (en) | 2013-11-20 |
CN102803239A (zh) | 2012-11-28 |
ZA201109103B (en) | 2012-08-29 |
US8716490B2 (en) | 2014-05-06 |
WO2010143661A1 (ja) | 2010-12-16 |
TWI437987B (zh) | 2014-05-21 |
RU2531350C2 (ru) | 2014-10-20 |
IL216856A0 (en) | 2012-03-01 |
ES2444500T3 (es) | 2014-02-25 |
US20120088805A1 (en) | 2012-04-12 |
CA2764782C (en) | 2017-07-25 |
NZ596960A (en) | 2013-04-26 |
US20130184236A1 (en) | 2013-07-18 |
AU2010259585B2 (en) | 2015-11-19 |
CN102803239B (zh) | 2015-04-15 |
EP2441760A4 (en) | 2012-12-05 |
BRPI1013152B1 (pt) | 2019-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230609 |