HK1163063A1 - Novel pyrazole-3-carboxamide derivate having 5-ht2b receptor antagonist activity 5-ht2b -3- - Google Patents

Novel pyrazole-3-carboxamide derivate having 5-ht2b receptor antagonist activity 5-ht2b -3-

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Publication number
HK1163063A1
HK1163063A1 HK12103083.8A HK12103083A HK1163063A1 HK 1163063 A1 HK1163063 A1 HK 1163063A1 HK 12103083 A HK12103083 A HK 12103083A HK 1163063 A1 HK1163063 A1 HK 1163063A1
Authority
HK
Hong Kong
Prior art keywords
ht2b
derivate
carboxamide
receptor antagonist
antagonist activity
Prior art date
Application number
HK12103083.8A
Other languages
English (en)
Chinese (zh)
Inventor
Tatsuya Yamagishi
Kiyoshi Kawamura
Tadashi Inoue
Yuji Shishido
Hiroaki Ito
Original Assignee
Raqualia Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raqualia Pharma Inc filed Critical Raqualia Pharma Inc
Publication of HK1163063A1 publication Critical patent/HK1163063A1/xx

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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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HK12103083.8A 2008-11-21 2012-03-28 Novel pyrazole-3-carboxamide derivate having 5-ht2b receptor antagonist activity 5-ht2b -3- HK1163063A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008298821 2008-11-21
JP2009112344 2009-05-01
PCT/JP2009/069816 WO2010058858A1 (ja) 2008-11-21 2009-11-24 ５－ｈｔ２ｂ受容体拮抗活性を有する新規ピラゾール－３－カルボキサミド誘導体

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HK1163063A1 true HK1163063A1 (en) 2012-09-07

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US (1) US8252790B2 (pt)
EP (1) EP2386546B1 (pt)
JP (1) JP5621148B2 (pt)
KR (1) KR101637337B1 (pt)
CN (1) CN102224142B (pt)
BR (1) BRPI0921097B8 (pt)
CA (1) CA2741511C (pt)
ES (1) ES2549005T3 (pt)
HK (1) HK1163063A1 (pt)
MX (1) MX2011005221A (pt)
RU (1) RU2528406C2 (pt)
WO (1) WO2010058858A1 (pt)

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KR101582335B1 (ko) * 2008-10-29 2016-01-04 삼성전자주식회사 휴대용 단말기에서 전압 강하 보상 장치 및 방법
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
US9394285B2 (en) 2013-03-15 2016-07-19 Pfizer Inc. Indole and indazole compounds that activate AMPK
EP3089972B1 (de) 2014-01-03 2018-05-16 Bayer Animal Health GmbH Neue pyrazolyl-heteroarylamide als schädlingsbekämpfungsmittel
WO2015116460A1 (en) * 2014-01-28 2015-08-06 Virginia Commonwealth University 2-substituted-5-hydroxy-4h-chromen-4-ones as novel ligands for the serotonin receptor 2b (5-ht2b)
WO2017070320A1 (en) * 2015-10-21 2017-04-27 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Phenyl indole allosteric inhibitors of p97 atpase
AU2016366310C1 (en) * 2015-12-09 2021-09-09 Research Triangle Institute Improved apelin receptor (APJ) agonists and uses thereof
EP3753924A1 (en) 2019-06-18 2020-12-23 AnaMar AB New tricyclic 5-ht2 antagonists
WO2021087181A1 (en) * 2019-11-01 2021-05-06 Bristol-Myers Squibb Company Substituted pyrazole compounds as toll receptor inhibitors
CN116710430A (zh) * 2020-05-12 2023-09-05 皮姆维制药公司 用于恢复突变p53功能的方法和化合物
CN116234552A (zh) 2020-07-29 2023-06-06 (株)倍宝尊 mGluR5和5-HT2A受体的双重调节剂及其用途
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WO2010058858A1 (ja) 2010-05-27
CN102224142B (zh) 2015-07-22
JPWO2010058858A1 (ja) 2012-04-19
RU2528406C2 (ru) 2014-09-20
US20110275628A1 (en) 2011-11-10
KR20110091550A (ko) 2011-08-11
KR101637337B1 (ko) 2016-07-07
CA2741511A1 (en) 2010-05-27
RU2011125314A (ru) 2012-12-27
EP2386546A4 (en) 2012-08-15
US8252790B2 (en) 2012-08-28
MX2011005221A (es) 2011-08-03
JP5621148B2 (ja) 2014-11-05
BRPI0921097A2 (pt) 2016-09-06
BRPI0921097B1 (pt) 2021-03-02
EP2386546B1 (en) 2015-08-19
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CN102224142A (zh) 2011-10-19

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