HK1162611A1 - 用於生成及擴增 庫以供 甲基化的靈敏檢測及分析用的方法 - Google Patents

用於生成及擴增 庫以供 甲基化的靈敏檢測及分析用的方法

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Publication number
HK1162611A1
HK1162611A1 HK12102762.8A HK12102762A HK1162611A1 HK 1162611 A1 HK1162611 A1 HK 1162611A1 HK 12102762 A HK12102762 A HK 12102762A HK 1162611 A1 HK1162611 A1 HK 1162611A1
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HK
Hong Kong
Prior art keywords
dna
analysis
generating
amplifying
sensitive detection
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Application number
HK12102762.8A
Other languages
English (en)
Inventor
Vladimir L Makarov
Emmanuel Kamberov
Tong Sun
Jonathon H Pinter
Brendan J Tarrier
Eric E Bruening
Takao Kurihara
Tim Tesmer
Joseph M Mmwirichia
Original Assignee
Rubicon Genomics Inc
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Publication date
Application filed by Rubicon Genomics Inc filed Critical Rubicon Genomics Inc
Publication of HK1162611A1 publication Critical patent/HK1162611A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK12102762.8A 2004-03-08 2007-05-18 用於生成及擴增 庫以供 甲基化的靈敏檢測及分析用的方法 HK1162611A1 (zh)

Applications Claiming Priority (1)

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US55194104P 2004-03-08 2004-03-08

Publications (1)

Publication Number Publication Date
HK1162611A1 true HK1162611A1 (zh) 2012-08-31

Family

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HK12102762.8A HK1162611A1 (zh) 2004-03-08 2007-05-18 用於生成及擴增 庫以供 甲基化的靈敏檢測及分析用的方法
HK07105296.3A HK1100960A1 (zh) 2004-03-08 2007-05-18 用於產生和擴增用於靈敏檢測和分析 甲基化的 文庫的方法和組合物

Family Applications After (1)

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HK07105296.3A HK1100960A1 (zh) 2004-03-08 2007-05-18 用於產生和擴增用於靈敏檢測和分析 甲基化的 文庫的方法和組合物

Country Status (5)

Country Link
US (3) US8440404B2 (zh)
EP (3) EP1725682B1 (zh)
CA (2) CA2559209C (zh)
HK (2) HK1162611A1 (zh)
WO (1) WO2005090607A1 (zh)

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EP2290106B1 (en) 2018-01-03
US9708652B2 (en) 2017-07-18
US8440404B2 (en) 2013-05-14
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EP1725682B1 (en) 2015-09-09
HK1100960A1 (zh) 2007-10-05
EP2290106A1 (en) 2011-03-02
CA2559209C (en) 2016-06-07
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US20180030527A1 (en) 2018-02-01

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