HK1100960A1 - 用於產生和擴增用於靈敏檢測和分析 甲基化的 文庫的方法和組合物 - Google Patents

用於產生和擴增用於靈敏檢測和分析 甲基化的 文庫的方法和組合物

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Publication number
HK1100960A1
HK1100960A1 HK07105296.3A HK07105296A HK1100960A1 HK 1100960 A1 HK1100960 A1 HK 1100960A1 HK 07105296 A HK07105296 A HK 07105296A HK 1100960 A1 HK1100960 A1 HK 1100960A1
Authority
HK
Hong Kong
Prior art keywords
dna
compositions
analysis
generating
methods
Prior art date
Application number
HK07105296.3A
Other languages
English (en)
Inventor
Vladimir L Makarov
Emmanuel Kamberov
Tong Sun
Jonathon H Pinter
Brendan J Tarrier
Eric E Bruening
Takao Kurihara
Tim Tesmer
Joseph M Mmwirichia
Original Assignee
Rubicon Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rubicon Genomics Inc filed Critical Rubicon Genomics Inc
Publication of HK1100960A1 publication Critical patent/HK1100960A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK07105296.3A 2004-03-08 2007-05-18 用於產生和擴增用於靈敏檢測和分析 甲基化的 文庫的方法和組合物 HK1100960A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55194104P 2004-03-08 2004-03-08
PCT/US2005/006979 WO2005090607A1 (en) 2004-03-08 2005-03-03 Methods and compositions for generating and amplifying dna libraries for sensitive detection and analysis of dna methylation

Publications (1)

Publication Number Publication Date
HK1100960A1 true HK1100960A1 (zh) 2007-10-05

Family

ID=34962131

Family Applications (2)

Application Number Title Priority Date Filing Date
HK12102762.8A HK1162611A1 (zh) 2004-03-08 2007-05-18 用於生成及擴增 庫以供 甲基化的靈敏檢測及分析用的方法
HK07105296.3A HK1100960A1 (zh) 2004-03-08 2007-05-18 用於產生和擴增用於靈敏檢測和分析 甲基化的 文庫的方法和組合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK12102762.8A HK1162611A1 (zh) 2004-03-08 2007-05-18 用於生成及擴增 庫以供 甲基化的靈敏檢測及分析用的方法

Country Status (5)

Country Link
US (3) US8440404B2 (zh)
EP (3) EP2380993B1 (zh)
CA (2) CA2902980A1 (zh)
HK (2) HK1162611A1 (zh)
WO (1) WO2005090607A1 (zh)

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US8440404B2 (en) 2013-05-14
US20050202490A1 (en) 2005-09-15
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CA2559209C (en) 2016-06-07
CA2902980A1 (en) 2005-09-29
US9708652B2 (en) 2017-07-18
WO2005090607A1 (en) 2005-09-29
US20130309668A1 (en) 2013-11-21
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